3OIIA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
Knots found
sequence length
225
structure length
216
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule keywords Essential for mitotic growth 1
total genus 67
structure length 216
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oiiA01
2I6DA 1NS5A 4YQDA 4MCDA 4YQ0A 4YPXA 3KNUA 2V3KA 3N4KA 3BBDA 3NK7A 2CX8A 1IPAA 4JAKA 3KTYA 5FAIA 4YVGA 5GMCA 1MXIA 4YQKA 4YQSA 4X3MA 4YQJA 4X3LA 1X7OA 4FAKA 3ILKA 4JALA 4IG6A 5D9FA 2HA8A 2EGWA 4YQ8A 3OIJA 4YQ4A 4YQCA 3L8UA 4YQ9A 2QMMA 3NK6A 4KGNA 4L69A 4YQ2A 4YQQA 3IEFA 4YVIA 3AXZA 4YQIA 1Z85A 1OY5A 4YVHA 1VHKA 1X7PA 4KDZA 4YPZA 3BBHA 1GZ0A 5GMBA 3OIIA 4YQLA 4H3ZA 4YVKA 4E8BA 3KW2A 3N4JA 2YY8A 4YVJA 3OINA 4J3CA 1TO0A 4CNFA 2EGVA 2O3AA 4YQ3A 2V3JA 4YQ7A 5CO4A 1V6ZA 1VHYA 4YQ1A 1VH0A 3GYQA 3QUVA 3ONPA 4YQAA 4CNDA 1P9PA 4CNGA 3AI9X 4YQNA 1UALA 4YPWA 3IC6A 4YQBA 1UAKA 4CNEA 3DCMX 4YPYA 1V2XA 4RG1A 4YQ5A 4YQRA 3BBEA 1UAMA 4MCCA 4MCBA 2QWVA 1ZJRA 3KY7A 1J85A 1K3RA 1UAJA 1NXZA 4YQ6A 4YQGA 2Z0YA 4YQOA 4YQTA 3E5YA 3O7BA 4PZKA 5GM8A 4XBOA 4YQPA 3AIAA 4H3YA 1O6DA
chains in the Genus database with same CATH superfamily
2I6DA 1NS5A 4YQDA 4MCDA 4YQ0A 4YPXA 3KNUA 2V3KA 3N4KA 3BBDA 3NK7A 2CX8A 1IPAA 4JAKA 3KTYA 5FAIA 4YVGA 5GMCA 1MXIA 4YQKA 4YQSA 4X3MA 4YQJA 4X3LA 1X7OA 4JWJA 4FAKA 3ILKA 4JALA 4IG6A 5D9FA 2HA8A 2EGWA 4YQ8A 3OIJA 4YQ4A 4YQCA 3L8UA 4YQ9A 2QMMA 3NK6A 4KGNA 4L69A 4YQ2A 4YQQA 3IEFA 4YVIA 3AXZA 4YQIA 1Z85A 1OY5A 4YVHA 1VHKA 1X7PA 4KDZA 4YPZA 3BBHA 1GZ0A 5GMBA 3OIIA 4YQLA 4H3ZA 4YVKA 4E8BA 3KW2A 3N4JA 2YY8A 4YVJA 3OINA 4J3CA 1TO0A 4CNFA 2EGVA 2O3AA 4YQ3A 2V3JA 4YQ7A 5CO4A 1V6ZA 1VHYA 4YQ1A 1VH0A 3GYQA 3QUVA 3ONPA 4YQAA 4CNDA 1P9PA 4CNGA 3AI9X 4YQNA 1UALA 4YPWA 3IC6A 4YQBA 1UAKA 4CNEA 3DCMX 4YPYA 1V2XA 4FMWA 4JWFA 4RG1A 4YQ5A 4YQRA 3BBEA 1UAMA 4MCCA 4MCBA 4JWGA 2QWVA 1ZJRA 3KY7A 1J85A 1K3RA 4JWHA 1UAJA 1NXZA 4YQ6A 4YQGA 2Z0YA 4YQOA 4YQTA 3E5YA 3O7BA 4PZKA 5GM8A 4XBOA 4YQPA 3AIAA 4H3YA 1O6DA
chains in the Genus database with same CATH topology
2I6DA 1NS5A 4YQDA 4MCDA 4YQ0A 4YPXA 3KNUA 2V3KA 3N4KA 3BBDA 3NK7A 2CX8A 1IPAA 4JAKA 3KTYA 5FAIA 4YVGA 5GMCA 1MXIA 4YQKA 4YQSA 4X3MA 4YQJA 4X3LA 1X7OA 4JWJA 4FAKA 3ILKA 4JALA 4IG6A 5D9FA 2HA8A 2EGWA 4YQ8A 3OIJA 4YQ4A 4YQCA 3L8UA 4YQ9A 2QMMA 3NK6A 4KGNA 4L69A 4YQ2A 4YQQA 3IEFA 4YVIA 3AXZA 4YQIA 1Z85A 1OY5A 4YVHA 1VHKA 1X7PA 4KDZA 4YPZA 3BBHA 1GZ0A 5GMBA 3OIIA 4YQLA 4H3ZA 4YVKA 4E8BA 3KW2A 3N4JA 2YY8A 4YVJA 3OINA 4J3CA 1TO0A 4CNFA 2EGVA 2O3AA 4YQ3A 2V3JA 4YQ7A 5CO4A 1V6ZA 1VHYA 4YQ1A 1VH0A 3GYQA 3QUVA 3ONPA 4YQAA 4CNDA 1P9PA 4CNGA 3AI9X 4YQNA 1UALA 4YPWA 3IC6A 4YQBA 1UAKA 4CNEA 3DCMX 4YPYA 1V2XA 4FMWA 4JWFA 4RG1A 4YQ5A 4YQRA 3BBEA 1UAMA 4MCCA 4MCBA 4JWGA 2QWVA 1ZJRA 3KY7A 1J85A 1K3RA 4JWHA 1UAJA 1NXZA 4YQ6A 4YQGA 2Z0YA 4YQOA 4YQTA 3E5YA 3O7BA 4PZKA 5GM8A 4XBOA 4YQPA 3AIAA 4H3YA 1O6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2I6D A;  1NS5 A;  4YQD A;  4MCD A;  4YQ0 A;  4YPX A;  3KNU A;  2V3K A;  3N4K A;  3BBD A;  3NK7 A;  2CX8 A;  1IPA A;  4JAK A;  3KTY A;  5FAI A;  4YVG A;  5GMC A;  1MXI A;  4YQK A;  4YQS A;  4X3M A;  4YQJ A;  4X3L A;  1X7O A;  4FAK A;  3ILK A;  4JAL A;  4IG6 A;  5D9F A;  2HA8 A;  2EGW A;  4YQ8 A;  3OIJ A;  4YQ4 A;  4YQC A;  3L8U A;  4YQ9 A;  2QMM A;  3NK6 A;  4KGN A;  4L69 A;  4YQ2 A;  4YQQ A;  3IEF A;  4YVI A;  3AXZ A;  4YQI A;  1Z85 A;  1OY5 A;  4YVH A;  1VHK A;  1X7P A;  4KDZ A;  4YPZ A;  3BBH A;  1GZ0 A;  5GMB A;  3OII A;  4YQL A;  4H3Z A;  4YVK A;  4E8B A;  3KW2 A;  3N4J A;  2YY8 A;  4YVJ A;  3OIN A;  4J3C A;  1TO0 A;  4CNF A;  2EGV A;  2O3A A;  4YQ3 A;  2V3J A;  4YQ7 A;  5CO4 A;  1V6Z A;  1VHY A;  4YQ1 A;  1VH0 A;  3GYQ A;  3QUV A;  3ONP A;  4YQA A;  4CND A;  1P9P A;  4CNG A;  3AI9 X;  4YQN A;  1UAL A;  4YPW A;  3IC6 A;  4YQB A;  1UAK A;  4CNE A;  3DCM X;  4YPY A;  1V2X A;  4RG1 A;  4YQ5 A;  4YQR A;  3BBE A;  1UAM A;  4MCC A;  4MCB A;  2QWV A;  1ZJR A;  3KY7 A;  1J85 A;  1K3R A;  1UAJ A;  1NXZ A;  4YQ6 A;  4YQG A;  2Z0Y A;  4YQO A;  4YQT A;  3E5Y A;  3O7B A;  4PZK A;  5GM8 A;  4XBO A;  4YQP A;  3AIA A;  4H3Y A;  1O6D A; 
#chains in the Genus database with same CATH topology
 2I6D A;  1NS5 A;  4YQD A;  4MCD A;  4YQ0 A;  4YPX A;  3KNU A;  2V3K A;  3N4K A;  3BBD A;  3NK7 A;  2CX8 A;  1IPA A;  4JAK A;  3KTY A;  5FAI A;  4YVG A;  5GMC A;  1MXI A;  4YQK A;  4YQS A;  4X3M A;  4YQJ A;  4X3L A;  1X7O A;  4JWJ A;  4FAK A;  3ILK A;  4JAL A;  4IG6 A;  5D9F A;  2HA8 A;  2EGW A;  4YQ8 A;  3OIJ A;  4YQ4 A;  4YQC A;  3L8U A;  4YQ9 A;  2QMM A;  3NK6 A;  4KGN A;  4L69 A;  4YQ2 A;  4YQQ A;  3IEF A;  4YVI A;  3AXZ A;  4YQI A;  1Z85 A;  1OY5 A;  4YVH A;  1VHK A;  1X7P A;  4KDZ A;  4YPZ A;  3BBH A;  1GZ0 A;  5GMB A;  3OII A;  4YQL A;  4H3Z A;  4YVK A;  4E8B A;  3KW2 A;  3N4J A;  2YY8 A;  4YVJ A;  3OIN A;  4J3C A;  1TO0 A;  4CNF A;  2EGV A;  2O3A A;  4YQ3 A;  2V3J A;  4YQ7 A;  5CO4 A;  1V6Z A;  1VHY A;  4YQ1 A;  1VH0 A;  3GYQ A;  3QUV A;  3ONP A;  4YQA A;  4CND A;  1P9P A;  4CNG A;  3AI9 X;  4YQN A;  1UAL A;  4YPW A;  3IC6 A;  4YQB A;  1UAK A;  4CNE A;  3DCM X;  4YPY A;  1V2X A;  4FMW A;  4JWF A;  4RG1 A;  4YQ5 A;  4YQR A;  3BBE A;  1UAM A;  4MCC A;  4MCB A;  4JWG A;  2QWV A;  1ZJR A;  3KY7 A;  1J85 A;  1K3R A;  4JWH A;  1UAJ A;  1NXZ A;  4YQ6 A;  4YQG A;  2Z0Y A;  4YQO A;  4YQT A;  3E5Y A;  3O7B A;  4PZK A;  5GM8 A;  4XBO A;  4YQP A;  3AIA A;  4H3Y A;  1O6D A; 
#chains in the Genus database with same CATH homology
 2I6D A;  1NS5 A;  4YQD A;  4MCD A;  4YQ0 A;  4YPX A;  3KNU A;  2V3K A;  3N4K A;  3BBD A;  3NK7 A;  2CX8 A;  1IPA A;  4JAK A;  3KTY A;  5FAI A;  4YVG A;  5GMC A;  1MXI A;  4YQK A;  4YQS A;  4X3M A;  4YQJ A;  4X3L A;  1X7O A;  4JWJ A;  4FAK A;  3ILK A;  4JAL A;  4IG6 A;  5D9F A;  2HA8 A;  2EGW A;  4YQ8 A;  3OIJ A;  4YQ4 A;  4YQC A;  3L8U A;  4YQ9 A;  2QMM A;  3NK6 A;  4KGN A;  4L69 A;  4YQ2 A;  4YQQ A;  3IEF A;  4YVI A;  3AXZ A;  4YQI A;  1Z85 A;  1OY5 A;  4YVH A;  1VHK A;  1X7P A;  4KDZ A;  4YPZ A;  3BBH A;  1GZ0 A;  5GMB A;  3OII A;  4YQL A;  4H3Z A;  4YVK A;  4E8B A;  3KW2 A;  3N4J A;  2YY8 A;  4YVJ A;  3OIN A;  4J3C A;  1TO0 A;  4CNF A;  2EGV A;  2O3A A;  4YQ3 A;  2V3J A;  4YQ7 A;  5CO4 A;  1V6Z A;  1VHY A;  4YQ1 A;  1VH0 A;  3GYQ A;  3QUV A;  3ONP A;  4YQA A;  4CND A;  1P9P A;  4CNG A;  3AI9 X;  4YQN A;  1UAL A;  4YPW A;  3IC6 A;  4YQB A;  1UAK A;  4CNE A;  3DCM X;  4YPY A;  1V2X A;  4FMW A;  4JWF A;  4RG1 A;  4YQ5 A;  4YQR A;  3BBE A;  1UAM A;  4MCC A;  4MCB A;  4JWG A;  2QWV A;  1ZJR A;  3KY7 A;  1J85 A;  1K3R A;  4JWH A;  1UAJ A;  1NXZ A;  4YQ6 A;  4YQG A;  2Z0Y A;  4YQO A;  4YQT A;  3E5Y A;  3O7B A;  4PZK A;  5GM8 A;  4XBO A;  4YQP A;  3AIA A;  4H3Y A;  1O6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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