3OIJA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 2 molecules of cognate rna
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
Knots found
sequence length
225
structure length
211
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIYVLLNCDDHQGLLDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 62
structure length 211
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oijA01
4YPYA 4E8BA 4FAKA 1UAJA 4YQBA 4YQ0A 2O3AA 4YVGA 1TO0A 2V3JA 4YQQA 4YQ7A 4H3ZA 4YQAA 1V2XA 1GZ0A 1UALA 1OY5A 1P9PA 1J85A 4MCCA 3N4KA 3OIIA 2QMMA 4IG6A 4YQ9A 4YQ4A 1UAKA 5D9FA 3ONPA 3BBHA 3BBEA 3IEFA 1Z85A 4YQJA 4CNGA 4YVIA 4YVJA 1O6DA 4YQ6A 2QWVA 4CNFA 4YPWA 2CX8A 1NS5A 5GMBA 4YVHA 3AI9X 4YQSA 4YQ1A 4YQPA 3L8UA 3KNUA 3AIAA 4X3MA 3DCMX 4YPZA 4YQDA 2EGWA 4YQIA 4KDZA 3NK7A 3IC6A 4YQ8A 4YVKA 3OINA 3KY7A 5GM8A 3E5YA 4H3YA 3N4JA 1IPAA 2V3KA 4YQCA 4KGNA 4YQTA 4MCDA 1UAMA 1K3RA 2I6DA 4J3CA 4YQLA 2Z0YA 4YQRA 1VHKA 1NXZA 4YQ2A 3KW2A 4YQGA 4CNEA 4RG1A 3ILKA 4CNDA 1VH0A 4L69A 3OIJA 5CO4A 1X7PA 4YQKA 2EGVA 4MCBA 2YY8A 3BBDA 4PZKA 4X3LA 3KTYA 4YQOA 1VHYA 3QUVA 2HA8A 3NK6A 5FAIA 3GYQA 1X7OA 4JAKA 4YQ3A 4XBOA 4YPXA 1ZJRA 5GMCA 1V6ZA 4JALA 1MXIA 3O7BA 3AXZA 4YQ5A 4YQNA
chains in the Genus database with same CATH superfamily
4YPYA 4E8BA 4FAKA 1UAJA 4YQBA 4YQ0A 2O3AA 4YVGA 1TO0A 2V3JA 4YQQA 4YQ7A 4H3ZA 4YQAA 1V2XA 1GZ0A 1UALA 1OY5A 1P9PA 1J85A 4JWHA 4MCCA 3N4KA 3OIIA 2QMMA 4IG6A 4YQ9A 4YQ4A 1UAKA 5D9FA 4FMWA 3ONPA 3BBHA 3BBEA 3IEFA 1Z85A 4YQJA 4CNGA 4YVIA 4YVJA 1O6DA 4YQ6A 2QWVA 4CNFA 4YPWA 2CX8A 1NS5A 5GMBA 4YVHA 3AI9X 4YQSA 4YQ1A 4YQPA 3L8UA 3KNUA 3AIAA 4X3MA 3DCMX 4YPZA 4YQDA 2EGWA 4YQIA 4KDZA 3NK7A 3IC6A 4YQ8A 4JWFA 4YVKA 3OINA 3KY7A 5GM8A 3E5YA 4H3YA 3N4JA 1IPAA 2V3KA 4YQCA 4KGNA 4YQTA 4MCDA 1UAMA 1K3RA 2I6DA 4J3CA 4YQLA 2Z0YA 4YQRA 1VHKA 1NXZA 4YQ2A 3KW2A 4YQGA 4CNEA 4RG1A 3ILKA 4CNDA 1VH0A 4L69A 4JWGA 3OIJA 5CO4A 1X7PA 4YQKA 2EGVA 4MCBA 2YY8A 3BBDA 4PZKA 4X3LA 3KTYA 4YQOA 1VHYA 3QUVA 2HA8A 3NK6A 5FAIA 4JWJA 3GYQA 1X7OA 4JAKA 4YQ3A 4XBOA 4YPXA 1ZJRA 5GMCA 1V6ZA 4JALA 1MXIA 3O7BA 3AXZA 4YQ5A 4YQNA
chains in the Genus database with same CATH topology
4YPYA 4E8BA 4FAKA 1UAJA 4YQBA 4YQ0A 2O3AA 4YVGA 1TO0A 2V3JA 4YQQA 4YQ7A 4H3ZA 4YQAA 1V2XA 1GZ0A 1UALA 1OY5A 1P9PA 1J85A 4JWHA 4MCCA 3N4KA 3OIIA 2QMMA 4IG6A 4YQ9A 4YQ4A 1UAKA 5D9FA 4FMWA 3ONPA 3BBHA 3BBEA 3IEFA 1Z85A 4YQJA 4CNGA 4YVIA 4YVJA 1O6DA 4YQ6A 2QWVA 4CNFA 4YPWA 2CX8A 1NS5A 5GMBA 4YVHA 3AI9X 4YQSA 4YQ1A 4YQPA 3L8UA 3KNUA 3AIAA 4X3MA 3DCMX 4YPZA 4YQDA 2EGWA 4YQIA 4KDZA 3NK7A 3IC6A 4YQ8A 4JWFA 4YVKA 3OINA 3KY7A 5GM8A 3E5YA 4H3YA 3N4JA 1IPAA 2V3KA 4YQCA 4KGNA 4YQTA 4MCDA 1UAMA 1K3RA 2I6DA 4J3CA 4YQLA 2Z0YA 4YQRA 1VHKA 1NXZA 4YQ2A 3KW2A 4YQGA 4CNEA 4RG1A 3ILKA 4CNDA 1VH0A 4L69A 4JWGA 3OIJA 5CO4A 1X7PA 4YQKA 2EGVA 4MCBA 2YY8A 3BBDA 4PZKA 4X3LA 3KTYA 4YQOA 1VHYA 3QUVA 2HA8A 3NK6A 5FAIA 4JWJA 3GYQA 1X7OA 4JAKA 4YQ3A 4XBOA 4YPXA 1ZJRA 5GMCA 1V6ZA 4JALA 1MXIA 3O7BA 3AXZA 4YQ5A 4YQNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YPY A;  4E8B A;  4FAK A;  1UAJ A;  4YQB A;  4YQ0 A;  2O3A A;  4YVG A;  1TO0 A;  2V3J A;  4YQQ A;  4YQ7 A;  4H3Z A;  4YQA A;  1V2X A;  1GZ0 A;  1UAL A;  1OY5 A;  1P9P A;  1J85 A;  4MCC A;  3N4K A;  3OII A;  2QMM A;  4IG6 A;  4YQ9 A;  4YQ4 A;  1UAK A;  5D9F A;  3ONP A;  3BBH A;  3BBE A;  3IEF A;  1Z85 A;  4YQJ A;  4CNG A;  4YVI A;  4YVJ A;  1O6D A;  4YQ6 A;  2QWV A;  4CNF A;  4YPW A;  2CX8 A;  1NS5 A;  5GMB A;  4YVH A;  3AI9 X;  4YQS A;  4YQ1 A;  4YQP A;  3L8U A;  3KNU A;  3AIA A;  4X3M A;  3DCM X;  4YPZ A;  4YQD A;  2EGW A;  4YQI A;  4KDZ A;  3NK7 A;  3IC6 A;  4YQ8 A;  4YVK A;  3OIN A;  3KY7 A;  5GM8 A;  3E5Y A;  4H3Y A;  3N4J A;  1IPA A;  2V3K A;  4YQC A;  4KGN A;  4YQT A;  4MCD A;  1UAM A;  1K3R A;  2I6D A;  4J3C A;  4YQL A;  2Z0Y A;  4YQR A;  1VHK A;  1NXZ A;  4YQ2 A;  3KW2 A;  4YQG A;  4CNE A;  4RG1 A;  3ILK A;  4CND A;  1VH0 A;  4L69 A;  3OIJ A;  5CO4 A;  1X7P A;  4YQK A;  2EGV A;  4MCB A;  2YY8 A;  3BBD A;  4PZK A;  4X3L A;  3KTY A;  4YQO A;  1VHY A;  3QUV A;  2HA8 A;  3NK6 A;  5FAI A;  3GYQ A;  1X7O A;  4JAK A;  4YQ3 A;  4XBO A;  4YPX A;  1ZJR A;  5GMC A;  1V6Z A;  4JAL A;  1MXI A;  3O7B A;  3AXZ A;  4YQ5 A;  4YQN A; 
#chains in the Genus database with same CATH topology
 4YPY A;  4E8B A;  4FAK A;  1UAJ A;  4YQB A;  4YQ0 A;  2O3A A;  4YVG A;  1TO0 A;  2V3J A;  4YQQ A;  4YQ7 A;  4H3Z A;  4YQA A;  1V2X A;  1GZ0 A;  1UAL A;  1OY5 A;  1P9P A;  1J85 A;  4JWH A;  4MCC A;  3N4K A;  3OII A;  2QMM A;  4IG6 A;  4YQ9 A;  4YQ4 A;  1UAK A;  5D9F A;  4FMW A;  3ONP A;  3BBH A;  3BBE A;  3IEF A;  1Z85 A;  4YQJ A;  4CNG A;  4YVI A;  4YVJ A;  1O6D A;  4YQ6 A;  2QWV A;  4CNF A;  4YPW A;  2CX8 A;  1NS5 A;  5GMB A;  4YVH A;  3AI9 X;  4YQS A;  4YQ1 A;  4YQP A;  3L8U A;  3KNU A;  3AIA A;  4X3M A;  3DCM X;  4YPZ A;  4YQD A;  2EGW A;  4YQI A;  4KDZ A;  3NK7 A;  3IC6 A;  4YQ8 A;  4JWF A;  4YVK A;  3OIN A;  3KY7 A;  5GM8 A;  3E5Y A;  4H3Y A;  3N4J A;  1IPA A;  2V3K A;  4YQC A;  4KGN A;  4YQT A;  4MCD A;  1UAM A;  1K3R A;  2I6D A;  4J3C A;  4YQL A;  2Z0Y A;  4YQR A;  1VHK A;  1NXZ A;  4YQ2 A;  3KW2 A;  4YQG A;  4CNE A;  4RG1 A;  3ILK A;  4CND A;  1VH0 A;  4L69 A;  4JWG A;  3OIJ A;  5CO4 A;  1X7P A;  4YQK A;  2EGV A;  4MCB A;  2YY8 A;  3BBD A;  4PZK A;  4X3L A;  3KTY A;  4YQO A;  1VHY A;  3QUV A;  2HA8 A;  3NK6 A;  5FAI A;  4JWJ A;  3GYQ A;  1X7O A;  4JAK A;  4YQ3 A;  4XBO A;  4YPX A;  1ZJR A;  5GMC A;  1V6Z A;  4JAL A;  1MXI A;  3O7B A;  3AXZ A;  4YQ5 A;  4YQN A; 
#chains in the Genus database with same CATH homology
 4YPY A;  4E8B A;  4FAK A;  1UAJ A;  4YQB A;  4YQ0 A;  2O3A A;  4YVG A;  1TO0 A;  2V3J A;  4YQQ A;  4YQ7 A;  4H3Z A;  4YQA A;  1V2X A;  1GZ0 A;  1UAL A;  1OY5 A;  1P9P A;  1J85 A;  4JWH A;  4MCC A;  3N4K A;  3OII A;  2QMM A;  4IG6 A;  4YQ9 A;  4YQ4 A;  1UAK A;  5D9F A;  4FMW A;  3ONP A;  3BBH A;  3BBE A;  3IEF A;  1Z85 A;  4YQJ A;  4CNG A;  4YVI A;  4YVJ A;  1O6D A;  4YQ6 A;  2QWV A;  4CNF A;  4YPW A;  2CX8 A;  1NS5 A;  5GMB A;  4YVH A;  3AI9 X;  4YQS A;  4YQ1 A;  4YQP A;  3L8U A;  3KNU A;  3AIA A;  4X3M A;  3DCM X;  4YPZ A;  4YQD A;  2EGW A;  4YQI A;  4KDZ A;  3NK7 A;  3IC6 A;  4YQ8 A;  4JWF A;  4YVK A;  3OIN A;  3KY7 A;  5GM8 A;  3E5Y A;  4H3Y A;  3N4J A;  1IPA A;  2V3K A;  4YQC A;  4KGN A;  4YQT A;  4MCD A;  1UAM A;  1K3R A;  2I6D A;  4J3C A;  4YQL A;  2Z0Y A;  4YQR A;  1VHK A;  1NXZ A;  4YQ2 A;  3KW2 A;  4YQG A;  4CNE A;  4RG1 A;  3ILK A;  4CND A;  1VH0 A;  4L69 A;  4JWG A;  3OIJ A;  5CO4 A;  1X7P A;  4YQK A;  2EGV A;  4MCB A;  2YY8 A;  3BBD A;  4PZK A;  4X3L A;  3KTY A;  4YQO A;  1VHY A;  3QUV A;  2HA8 A;  3NK6 A;  5FAI A;  4JWJ A;  3GYQ A;  1X7O A;  4JAK A;  4YQ3 A;  4XBO A;  4YPX A;  1ZJR A;  5GMC A;  1V6Z A;  4JAL A;  1MXI A;  3O7B A;  3AXZ A;  4YQ5 A;  4YQN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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