3OINA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 1 molecule of cognate rna
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
225
structure length
217
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 66
structure length 217
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oinA01
4YQ9A 4YVHA 2V3KA 3OIJA 1VHKA 5GM8A 3N4JA 2I6DA 3KY7A 4YQJA 1Z85A 4X3LA 2QMMA 4YQ4A 4YQ6A 1OY5A 3AIAA 2O3AA 4CNEA 1VHYA 3DCMX 3NK6A 5GMBA 4YQ1A 4YQLA 1J85A 4YQNA 4L69A 1X7PA 4YQDA 4YQ7A 3ONPA 5D9FA 4YQ2A 4CNDA 3OIIA 4FAKA 4CNGA 4YQCA 4YQ3A 4YQBA 1X7OA 4H3YA 1K3RA 4PZKA 4YPXA 1MXIA 1UAJA 2EGVA 4MCBA 3KNUA 3N4KA 2EGWA 3IEFA 1V2XA 4J3CA 1ZJRA 4YPZA 3KTYA 1P9PA 1V6ZA 4YQQA 1IPAA 4MCCA 4YQ5A 3L8UA 5GMCA 4YPYA 4YQAA 4KGNA 2HA8A 4RG1A 4YQ0A 3AI9X 2V3JA 4YQIA 2CX8A 3O7BA 2QWVA 3BBHA 5CO4A 4XBOA 1NXZA 3IC6A 3KW2A 1UALA 1UAKA 4YPWA 3E5YA 1O6DA 5FAIA 4JALA 4YVJA 4YQ8A 4YQRA 1TO0A 2Z0YA 4X3MA 2YY8A 4YVIA 3BBDA 4JAKA 3GYQA 4KDZA 4YQOA 1GZ0A 1VH0A 3QUVA 4YVKA 3NK7A 4CNFA 4YQKA 4E8BA 3ILKA 4YQTA 4IG6A 1NS5A 1UAMA 4YQGA 4YVGA 4YQPA 4H3ZA 4MCDA 3BBEA 3AXZA 4YQSA 3OINA
chains in the Genus database with same CATH superfamily
4YQ9A 4YVHA 2V3KA 3OIJA 1VHKA 5GM8A 3N4JA 2I6DA 3KY7A 4YQJA 1Z85A 4X3LA 2QMMA 4YQ4A 4JWFA 4YQ6A 1OY5A 3AIAA 2O3AA 4CNEA 1VHYA 4FMWA 3DCMX 3NK6A 5GMBA 4YQ1A 4YQLA 1J85A 4YQNA 4L69A 1X7PA 4YQDA 4YQ7A 3ONPA 5D9FA 4YQ2A 4CNDA 3OIIA 4FAKA 4CNGA 4YQCA 4YQ3A 4YQBA 1X7OA 4H3YA 1K3RA 4PZKA 4YPXA 1MXIA 1UAJA 2EGVA 4MCBA 3KNUA 3N4KA 2EGWA 3IEFA 1V2XA 4JWHA 4J3CA 1ZJRA 4YPZA 3KTYA 1P9PA 1V6ZA 4JWJA 4YQQA 1IPAA 4MCCA 4YQ5A 3L8UA 5GMCA 4YPYA 4YQAA 4KGNA 2HA8A 4RG1A 4YQ0A 3AI9X 2V3JA 4YQIA 2CX8A 3O7BA 2QWVA 3BBHA 5CO4A 4XBOA 1NXZA 3IC6A 3KW2A 1UALA 1UAKA 4YPWA 3E5YA 1O6DA 5FAIA 4JALA 4YVJA 4YQ8A 4YQRA 1TO0A 2Z0YA 4X3MA 2YY8A 4YVIA 3BBDA 4JAKA 3GYQA 4KDZA 4YQOA 1GZ0A 1VH0A 3QUVA 4YVKA 3NK7A 4CNFA 4YQKA 4E8BA 3ILKA 4YQTA 4IG6A 1NS5A 1UAMA 4YQGA 4JWGA 4YVGA 4YQPA 4H3ZA 4MCDA 3BBEA 3AXZA 4YQSA 3OINA
chains in the Genus database with same CATH topology
4YQ9A 4YVHA 2V3KA 3OIJA 1VHKA 5GM8A 3N4JA 2I6DA 3KY7A 4YQJA 1Z85A 4X3LA 2QMMA 4YQ4A 4JWFA 4YQ6A 1OY5A 3AIAA 2O3AA 4CNEA 1VHYA 4FMWA 3DCMX 3NK6A 5GMBA 4YQ1A 4YQLA 1J85A 4YQNA 4L69A 1X7PA 4YQDA 4YQ7A 3ONPA 5D9FA 4YQ2A 4CNDA 3OIIA 4FAKA 4CNGA 4YQCA 4YQ3A 4YQBA 1X7OA 4H3YA 1K3RA 4PZKA 4YPXA 1MXIA 1UAJA 2EGVA 4MCBA 3KNUA 3N4KA 2EGWA 3IEFA 1V2XA 4JWHA 4J3CA 1ZJRA 4YPZA 3KTYA 1P9PA 1V6ZA 4JWJA 4YQQA 1IPAA 4MCCA 4YQ5A 3L8UA 5GMCA 4YPYA 4YQAA 4KGNA 2HA8A 4RG1A 4YQ0A 3AI9X 2V3JA 4YQIA 2CX8A 3O7BA 2QWVA 3BBHA 5CO4A 4XBOA 1NXZA 3IC6A 3KW2A 1UALA 1UAKA 4YPWA 3E5YA 1O6DA 5FAIA 4JALA 4YVJA 4YQ8A 4YQRA 1TO0A 2Z0YA 4X3MA 2YY8A 4YVIA 3BBDA 4JAKA 3GYQA 4KDZA 4YQOA 1GZ0A 1VH0A 3QUVA 4YVKA 3NK7A 4CNFA 4YQKA 4E8BA 3ILKA 4YQTA 4IG6A 1NS5A 1UAMA 4YQGA 4JWGA 4YVGA 4YQPA 4H3ZA 4MCDA 3BBEA 3AXZA 4YQSA 3OINA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQ9 A;  4YVH A;  2V3K A;  3OIJ A;  1VHK A;  5GM8 A;  3N4J A;  2I6D A;  3KY7 A;  4YQJ A;  1Z85 A;  4X3L A;  2QMM A;  4YQ4 A;  4YQ6 A;  1OY5 A;  3AIA A;  2O3A A;  4CNE A;  1VHY A;  3DCM X;  3NK6 A;  5GMB A;  4YQ1 A;  4YQL A;  1J85 A;  4YQN A;  4L69 A;  1X7P A;  4YQD A;  4YQ7 A;  3ONP A;  5D9F A;  4YQ2 A;  4CND A;  3OII A;  4FAK A;  4CNG A;  4YQC A;  4YQ3 A;  4YQB A;  1X7O A;  4H3Y A;  1K3R A;  4PZK A;  4YPX A;  1MXI A;  1UAJ A;  2EGV A;  4MCB A;  3KNU A;  3N4K A;  2EGW A;  3IEF A;  1V2X A;  4J3C A;  1ZJR A;  4YPZ A;  3KTY A;  1P9P A;  1V6Z A;  4YQQ A;  1IPA A;  4MCC A;  4YQ5 A;  3L8U A;  5GMC A;  4YPY A;  4YQA A;  4KGN A;  2HA8 A;  4RG1 A;  4YQ0 A;  3AI9 X;  2V3J A;  4YQI A;  2CX8 A;  3O7B A;  2QWV A;  3BBH A;  5CO4 A;  4XBO A;  1NXZ A;  3IC6 A;  3KW2 A;  1UAL A;  1UAK A;  4YPW A;  3E5Y A;  1O6D A;  5FAI A;  4JAL A;  4YVJ A;  4YQ8 A;  4YQR A;  1TO0 A;  2Z0Y A;  4X3M A;  2YY8 A;  4YVI A;  3BBD A;  4JAK A;  3GYQ A;  4KDZ A;  4YQO A;  1GZ0 A;  1VH0 A;  3QUV A;  4YVK A;  3NK7 A;  4CNF A;  4YQK A;  4E8B A;  3ILK A;  4YQT A;  4IG6 A;  1NS5 A;  1UAM A;  4YQG A;  4YVG A;  4YQP A;  4H3Z A;  4MCD A;  3BBE A;  3AXZ A;  4YQS A;  3OIN A; 
#chains in the Genus database with same CATH topology
 4YQ9 A;  4YVH A;  2V3K A;  3OIJ A;  1VHK A;  5GM8 A;  3N4J A;  2I6D A;  3KY7 A;  4YQJ A;  1Z85 A;  4X3L A;  2QMM A;  4YQ4 A;  4JWF A;  4YQ6 A;  1OY5 A;  3AIA A;  2O3A A;  4CNE A;  1VHY A;  4FMW A;  3DCM X;  3NK6 A;  5GMB A;  4YQ1 A;  4YQL A;  1J85 A;  4YQN A;  4L69 A;  1X7P A;  4YQD A;  4YQ7 A;  3ONP A;  5D9F A;  4YQ2 A;  4CND A;  3OII A;  4FAK A;  4CNG A;  4YQC A;  4YQ3 A;  4YQB A;  1X7O A;  4H3Y A;  1K3R A;  4PZK A;  4YPX A;  1MXI A;  1UAJ A;  2EGV A;  4MCB A;  3KNU A;  3N4K A;  2EGW A;  3IEF A;  1V2X A;  4JWH A;  4J3C A;  1ZJR A;  4YPZ A;  3KTY A;  1P9P A;  1V6Z A;  4JWJ A;  4YQQ A;  1IPA A;  4MCC A;  4YQ5 A;  3L8U A;  5GMC A;  4YPY A;  4YQA A;  4KGN A;  2HA8 A;  4RG1 A;  4YQ0 A;  3AI9 X;  2V3J A;  4YQI A;  2CX8 A;  3O7B A;  2QWV A;  3BBH A;  5CO4 A;  4XBO A;  1NXZ A;  3IC6 A;  3KW2 A;  1UAL A;  1UAK A;  4YPW A;  3E5Y A;  1O6D A;  5FAI A;  4JAL A;  4YVJ A;  4YQ8 A;  4YQR A;  1TO0 A;  2Z0Y A;  4X3M A;  2YY8 A;  4YVI A;  3BBD A;  4JAK A;  3GYQ A;  4KDZ A;  4YQO A;  1GZ0 A;  1VH0 A;  3QUV A;  4YVK A;  3NK7 A;  4CNF A;  4YQK A;  4E8B A;  3ILK A;  4YQT A;  4IG6 A;  1NS5 A;  1UAM A;  4YQG A;  4JWG A;  4YVG A;  4YQP A;  4H3Z A;  4MCD A;  3BBE A;  3AXZ A;  4YQS A;  3OIN A; 
#chains in the Genus database with same CATH homology
 4YQ9 A;  4YVH A;  2V3K A;  3OIJ A;  1VHK A;  5GM8 A;  3N4J A;  2I6D A;  3KY7 A;  4YQJ A;  1Z85 A;  4X3L A;  2QMM A;  4YQ4 A;  4JWF A;  4YQ6 A;  1OY5 A;  3AIA A;  2O3A A;  4CNE A;  1VHY A;  4FMW A;  3DCM X;  3NK6 A;  5GMB A;  4YQ1 A;  4YQL A;  1J85 A;  4YQN A;  4L69 A;  1X7P A;  4YQD A;  4YQ7 A;  3ONP A;  5D9F A;  4YQ2 A;  4CND A;  3OII A;  4FAK A;  4CNG A;  4YQC A;  4YQ3 A;  4YQB A;  1X7O A;  4H3Y A;  1K3R A;  4PZK A;  4YPX A;  1MXI A;  1UAJ A;  2EGV A;  4MCB A;  3KNU A;  3N4K A;  2EGW A;  3IEF A;  1V2X A;  4JWH A;  4J3C A;  1ZJR A;  4YPZ A;  3KTY A;  1P9P A;  1V6Z A;  4JWJ A;  4YQQ A;  1IPA A;  4MCC A;  4YQ5 A;  3L8U A;  5GMC A;  4YPY A;  4YQA A;  4KGN A;  2HA8 A;  4RG1 A;  4YQ0 A;  3AI9 X;  2V3J A;  4YQI A;  2CX8 A;  3O7B A;  2QWV A;  3BBH A;  5CO4 A;  4XBO A;  1NXZ A;  3IC6 A;  3KW2 A;  1UAL A;  1UAK A;  4YPW A;  3E5Y A;  1O6D A;  5FAI A;  4JAL A;  4YVJ A;  4YQ8 A;  4YQR A;  1TO0 A;  2Z0Y A;  4X3M A;  2YY8 A;  4YVI A;  3BBD A;  4JAK A;  3GYQ A;  4KDZ A;  4YQO A;  1GZ0 A;  1VH0 A;  3QUV A;  4YVK A;  3NK7 A;  4CNF A;  4YQK A;  4E8B A;  3ILK A;  4YQT A;  4IG6 A;  1NS5 A;  1UAM A;  4YQG A;  4JWG A;  4YVG A;  4YQP A;  4H3Z A;  4MCD A;  3BBE A;  3AXZ A;  4YQS A;  3OIN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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