3OINA

Crystal structure of saccharomyces cerevisiae nep1/emg1 bound to s-adenosylhomocysteine and 1 molecule of cognate rna
Total Genus 66
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
Knots found
sequence length
225
structure length
217
Chain Sequence
PPVLTSKDKITKRMIVVLAMASLETHKIKYVLLNCDDHQGLLKKMGRDISEARPDITHQCLLTLLDSPINKAGKLQVYIQTSRGILIEVNPTVRIPRTFKRFSGLMVQLLHKLSIRSVNSEEKLLKVIKNPITDHLPTKCRKVTLSFDAPVIRVQDYIEKLDDDESICVFVGAMARGKDNFADEYVDEKVGLSNYPLSASVACSKFCHGAEDAWNIL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis.
pubmed doi rcsb
molecule tags Ribosomal protein
source organism Saccharomyces cerevisiae
molecule keywords Essential for mitotic growth 1
total genus 66
structure length 217
sequence length 225
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.260: rRNA small subunit pseudouridine methyltransferase Nep1.
pdb deposition date 2010-08-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03587 EMG1 EMG1/NEP1 methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 3oinA01
3KTYA 4FAKA 1Z85A 4YQ2A 1IPAA 3KW2A 4YQ8A 4YQTA 4YQGA 3OIJA 5GMBA 4YQDA 1TO0A 4IG6A 2HA8A 2QWVA 3ONPA 3L8UA 4PZKA 3IC6A 3OIIA 4YQNA 4KGNA 3NK7A 3BBDA 4JALA 4MCDA 4CNGA 4RG1A 1P9PA 2Z0YA 3O7BA 3N4KA 3IEFA 2V3KA 4YQRA 4H3YA 4YQJA 1UAMA 1K3RA 2EGWA 1VHYA 4CNFA 3OINA 5FAIA 4KDZA 4J3CA 4MCBA 1OY5A 4YVKA 3AXZA 1X7PA 1NS5A 4YQOA 4YQ9A 4YQ6A 2YY8A 4YQIA 3N4JA 4YVGA 1O6DA 4YQ0A 4YQKA 1UAKA 4YPXA 4X3MA 2CX8A 4YQBA 4YVIA 1GZ0A 1V2XA 4YPZA 5GM8A 4YQQA 3BBEA 3ILKA 4YPYA 3KNUA 5GMCA 2QMMA 4YVHA 4CNDA 3GYQA 3DCMX 3BBHA 1MXIA 3NK6A 4YQSA 4CNEA 4YQLA 1ZJRA 2EGVA 1UAJA 4H3ZA 4YQAA 1NXZA 4L69A 4YQ5A 1VH0A 4JAKA 4MCCA 1J85A 4X3LA 1VHKA 1UALA 4XBOA 2O3AA 1X7OA 4YQ7A 3AI9X 3QUVA 5CO4A 4YPWA 4E8BA 2V3JA 1V6ZA 3KY7A 4YQ4A 4YQCA 4YQ1A 3E5YA 4YVJA 2I6DA 4YQPA 5D9FA 3AIAA 4YQ3A
chains in the Genus database with same CATH superfamily
3KTYA 4FAKA 1Z85A 4YQ2A 1IPAA 3KW2A 4YQ8A 4YQTA 4YQGA 3OIJA 5GMBA 4YQDA 1TO0A 4IG6A 2HA8A 2QWVA 3ONPA 3L8UA 4PZKA 3IC6A 3OIIA 4YQNA 4KGNA 3NK7A 3BBDA 4JALA 4MCDA 4CNGA 4RG1A 1P9PA 2Z0YA 3O7BA 3N4KA 3IEFA 2V3KA 4YQRA 4H3YA 4YQJA 1UAMA 1K3RA 2EGWA 1VHYA 4CNFA 3OINA 5FAIA 4KDZA 4J3CA 4FMWA 4MCBA 1OY5A 4YVKA 3AXZA 1X7PA 1NS5A 4YQOA 4JWHA 4YQ9A 4YQ6A 2YY8A 4YQIA 3N4JA 4YVGA 1O6DA 4YQ0A 4YQKA 1UAKA 4YPXA 4X3MA 2CX8A 4YQBA 4YVIA 4JWJA 1GZ0A 1V2XA 4YPZA 5GM8A 4YQQA 3BBEA 3ILKA 4YPYA 3KNUA 5GMCA 2QMMA 4YVHA 4CNDA 3GYQA 3DCMX 3BBHA 1MXIA 3NK6A 4YQSA 4CNEA 4YQLA 1ZJRA 2EGVA 1UAJA 4H3ZA 4YQAA 1NXZA 4L69A 4YQ5A 1VH0A 4JAKA 4MCCA 1J85A 4X3LA 1VHKA 1UALA 4XBOA 2O3AA 1X7OA 4YQ7A 3AI9X 3QUVA 5CO4A 4JWFA 4YPWA 4E8BA 4JWGA 2V3JA 1V6ZA 3KY7A 4YQ4A 4YQCA 4YQ1A 3E5YA 4YVJA 2I6DA 4YQPA 5D9FA 3AIAA 4YQ3A
chains in the Genus database with same CATH topology
3KTYA 4FAKA 1Z85A 4YQ2A 1IPAA 3KW2A 4YQ8A 4YQTA 4YQGA 3OIJA 5GMBA 4YQDA 1TO0A 4IG6A 2HA8A 2QWVA 3ONPA 3L8UA 4PZKA 3IC6A 3OIIA 4YQNA 4KGNA 3NK7A 3BBDA 4JALA 4MCDA 4CNGA 4RG1A 1P9PA 2Z0YA 3O7BA 3N4KA 3IEFA 2V3KA 4YQRA 4H3YA 4YQJA 1UAMA 1K3RA 2EGWA 1VHYA 4CNFA 3OINA 5FAIA 4KDZA 4J3CA 4FMWA 4MCBA 1OY5A 4YVKA 3AXZA 1X7PA 1NS5A 4YQOA 4JWHA 4YQ9A 4YQ6A 2YY8A 4YQIA 3N4JA 4YVGA 1O6DA 4YQ0A 4YQKA 1UAKA 4YPXA 4X3MA 2CX8A 4YQBA 4YVIA 4JWJA 1GZ0A 1V2XA 4YPZA 5GM8A 4YQQA 3BBEA 3ILKA 4YPYA 3KNUA 5GMCA 2QMMA 4YVHA 4CNDA 3GYQA 3DCMX 3BBHA 1MXIA 3NK6A 4YQSA 4CNEA 4YQLA 1ZJRA 2EGVA 1UAJA 4H3ZA 4YQAA 1NXZA 4L69A 4YQ5A 1VH0A 4JAKA 4MCCA 1J85A 4X3LA 1VHKA 1UALA 4XBOA 2O3AA 1X7OA 4YQ7A 3AI9X 3QUVA 5CO4A 4JWFA 4YPWA 4E8BA 4JWGA 2V3JA 1V6ZA 3KY7A 4YQ4A 4YQCA 4YQ1A 3E5YA 4YVJA 2I6DA 4YQPA 5D9FA 3AIAA 4YQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KTY A;  4FAK A;  1Z85 A;  4YQ2 A;  1IPA A;  3KW2 A;  4YQ8 A;  4YQT A;  4YQG A;  3OIJ A;  5GMB A;  4YQD A;  1TO0 A;  4IG6 A;  2HA8 A;  2QWV A;  3ONP A;  3L8U A;  4PZK A;  3IC6 A;  3OII A;  4YQN A;  4KGN A;  3NK7 A;  3BBD A;  4JAL A;  4MCD A;  4CNG A;  4RG1 A;  1P9P A;  2Z0Y A;  3O7B A;  3N4K A;  3IEF A;  2V3K A;  4YQR A;  4H3Y A;  4YQJ A;  1UAM A;  1K3R A;  2EGW A;  1VHY A;  4CNF A;  3OIN A;  5FAI A;  4KDZ A;  4J3C A;  4MCB A;  1OY5 A;  4YVK A;  3AXZ A;  1X7P A;  1NS5 A;  4YQO A;  4YQ9 A;  4YQ6 A;  2YY8 A;  4YQI A;  3N4J A;  4YVG A;  1O6D A;  4YQ0 A;  4YQK A;  1UAK A;  4YPX A;  4X3M A;  2CX8 A;  4YQB A;  4YVI A;  1GZ0 A;  1V2X A;  4YPZ A;  5GM8 A;  4YQQ A;  3BBE A;  3ILK A;  4YPY A;  3KNU A;  5GMC A;  2QMM A;  4YVH A;  4CND A;  3GYQ A;  3DCM X;  3BBH A;  1MXI A;  3NK6 A;  4YQS A;  4CNE A;  4YQL A;  1ZJR A;  2EGV A;  1UAJ A;  4H3Z A;  4YQA A;  1NXZ A;  4L69 A;  4YQ5 A;  1VH0 A;  4JAK A;  4MCC A;  1J85 A;  4X3L A;  1VHK A;  1UAL A;  4XBO A;  2O3A A;  1X7O A;  4YQ7 A;  3AI9 X;  3QUV A;  5CO4 A;  4YPW A;  4E8B A;  2V3J A;  1V6Z A;  3KY7 A;  4YQ4 A;  4YQC A;  4YQ1 A;  3E5Y A;  4YVJ A;  2I6D A;  4YQP A;  5D9F A;  3AIA A;  4YQ3 A; 
#chains in the Genus database with same CATH topology
 3KTY A;  4FAK A;  1Z85 A;  4YQ2 A;  1IPA A;  3KW2 A;  4YQ8 A;  4YQT A;  4YQG A;  3OIJ A;  5GMB A;  4YQD A;  1TO0 A;  4IG6 A;  2HA8 A;  2QWV A;  3ONP A;  3L8U A;  4PZK A;  3IC6 A;  3OII A;  4YQN A;  4KGN A;  3NK7 A;  3BBD A;  4JAL A;  4MCD A;  4CNG A;  4RG1 A;  1P9P A;  2Z0Y A;  3O7B A;  3N4K A;  3IEF A;  2V3K A;  4YQR A;  4H3Y A;  4YQJ A;  1UAM A;  1K3R A;  2EGW A;  1VHY A;  4CNF A;  3OIN A;  5FAI A;  4KDZ A;  4J3C A;  4FMW A;  4MCB A;  1OY5 A;  4YVK A;  3AXZ A;  1X7P A;  1NS5 A;  4YQO A;  4JWH A;  4YQ9 A;  4YQ6 A;  2YY8 A;  4YQI A;  3N4J A;  4YVG A;  1O6D A;  4YQ0 A;  4YQK A;  1UAK A;  4YPX A;  4X3M A;  2CX8 A;  4YQB A;  4YVI A;  4JWJ A;  1GZ0 A;  1V2X A;  4YPZ A;  5GM8 A;  4YQQ A;  3BBE A;  3ILK A;  4YPY A;  3KNU A;  5GMC A;  2QMM A;  4YVH A;  4CND A;  3GYQ A;  3DCM X;  3BBH A;  1MXI A;  3NK6 A;  4YQS A;  4CNE A;  4YQL A;  1ZJR A;  2EGV A;  1UAJ A;  4H3Z A;  4YQA A;  1NXZ A;  4L69 A;  4YQ5 A;  1VH0 A;  4JAK A;  4MCC A;  1J85 A;  4X3L A;  1VHK A;  1UAL A;  4XBO A;  2O3A A;  1X7O A;  4YQ7 A;  3AI9 X;  3QUV A;  5CO4 A;  4JWF A;  4YPW A;  4E8B A;  4JWG A;  2V3J A;  1V6Z A;  3KY7 A;  4YQ4 A;  4YQC A;  4YQ1 A;  3E5Y A;  4YVJ A;  2I6D A;  4YQP A;  5D9F A;  3AIA A;  4YQ3 A; 
#chains in the Genus database with same CATH homology
 3KTY A;  4FAK A;  1Z85 A;  4YQ2 A;  1IPA A;  3KW2 A;  4YQ8 A;  4YQT A;  4YQG A;  3OIJ A;  5GMB A;  4YQD A;  1TO0 A;  4IG6 A;  2HA8 A;  2QWV A;  3ONP A;  3L8U A;  4PZK A;  3IC6 A;  3OII A;  4YQN A;  4KGN A;  3NK7 A;  3BBD A;  4JAL A;  4MCD A;  4CNG A;  4RG1 A;  1P9P A;  2Z0Y A;  3O7B A;  3N4K A;  3IEF A;  2V3K A;  4YQR A;  4H3Y A;  4YQJ A;  1UAM A;  1K3R A;  2EGW A;  1VHY A;  4CNF A;  3OIN A;  5FAI A;  4KDZ A;  4J3C A;  4FMW A;  4MCB A;  1OY5 A;  4YVK A;  3AXZ A;  1X7P A;  1NS5 A;  4YQO A;  4JWH A;  4YQ9 A;  4YQ6 A;  2YY8 A;  4YQI A;  3N4J A;  4YVG A;  1O6D A;  4YQ0 A;  4YQK A;  1UAK A;  4YPX A;  4X3M A;  2CX8 A;  4YQB A;  4YVI A;  4JWJ A;  1GZ0 A;  1V2X A;  4YPZ A;  5GM8 A;  4YQQ A;  3BBE A;  3ILK A;  4YPY A;  3KNU A;  5GMC A;  2QMM A;  4YVH A;  4CND A;  3GYQ A;  3DCM X;  3BBH A;  1MXI A;  3NK6 A;  4YQS A;  4CNE A;  4YQL A;  1ZJR A;  2EGV A;  1UAJ A;  4H3Z A;  4YQA A;  1NXZ A;  4L69 A;  4YQ5 A;  1VH0 A;  4JAK A;  4MCC A;  1J85 A;  4X3L A;  1VHK A;  1UAL A;  4XBO A;  2O3A A;  1X7O A;  4YQ7 A;  3AI9 X;  3QUV A;  5CO4 A;  4JWF A;  4YPW A;  4E8B A;  4JWG A;  2V3J A;  1V6Z A;  3KY7 A;  4YQ4 A;  4YQC A;  4YQ1 A;  3E5Y A;  4YVJ A;  2I6D A;  4YQP A;  5D9F A;  3AIA A;  4YQ3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...