4HKNC

Complex structure of human tankyrase 2 with luteolin
Total Genus 1
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
1
sequence length
47
structure length
47
Chain Sequence
MAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords Tankyrase-2
publication title Screening and structural analysis of flavones inhibiting tankyrases.
pubmed doi rcsb
source organism Homo sapiens
total genus 1
structure length 47
sequence length 47
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 4hknC00
4L32C 4L31C 4UI4C 5ADRB 4L0IC 5C5QC 4UVPB 4KZLC 4HKIC 4UI7C 4L09C 4L0TC 5ADQB 4HLGC 4KZQC 5FPFC 4HL5C 4L0VC 4HLHC 4L2KC 4L34C 4HKNC 4UI3C 4UI8C 4L0BC 4L0SC 4UI6C 4L2GC 4L2FC 5ADSB 5C5PC 4L10C 4HLMC 5ADTB 5C5RC 4HLFC 4HMHC 4KZUC 4HLKC 4L33C 4HKKB 4UI5C
chains in the Genus database with same CATH superfamily
4L32C 3OEIE 4L31C 3OEIA 4UI4C 3D55A 5ADRB 4L0IC 5C5QC 3K6QA 4UVPB 4KZLC 4HKIC 4UI7C 3HRYA 3G5OA 4L0TC 4L09C 4L33C 5ADQB 4HKKB 4HLGC 4KZQC 5FPFC 4ZM0A 4HL5C 4HLHC 4L0VC 4L2KC 4L34C 4ZM2A 4HKNC 4UI3C 4UI8C 4L0BC 4L0SC 4UI6C 2ZIXB 2A6QA 4L2GC 4L2FC 5ADSB 5C5PC 4L10C 3K33B 4HLMC 5ADTB 5C5RC 4HLFC 3KH2E 3HJ6A 4HMHC 4KZUC 3CTOA 4HLKC 2ODKA 3HS2A 4ZLXA 4UI5C
chains in the Genus database with same CATH topology
4L32C 4L31C 4UI4C 5ADRB 4L0IC 5C5QC 4UVPB 4KZLC 4HKIC 4UI7C 4L0TC 4L09C 5ADQB 4HLGC 4KZQC 5FPFC 4HL5C 4L0VC 4HLHC 4L2KC 4L34C 4HKNC 4UI3C 4UI8C 4L0BC 4L0SC 4UI6C 2ZIXB 4L2GC 4L2FC 5ADSB 5C5PC 4L10C 4HLMC 5ADTB 5C5RC 4HLFC 3HJ6A 4HMHC 4KZUC 4HLKC 4L33C 4HKKB 4UI5C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L32 C;  4L31 C;  4UI4 C;  5ADR B;  4L0I C;  5C5Q C;  4UVP B;  4KZL C;  4HKI C;  4UI7 C;  4L09 C;  4L0T C;  5ADQ B;  4HLG C;  4KZQ C;  5FPF C;  4HL5 C;  4L0V C;  4HLH C;  4L2K C;  4L34 C;  4HKN C;  4UI3 C;  4UI8 C;  4L0B C;  4L0S C;  4UI6 C;  4L2G C;  4L2F C;  5ADS B;  5C5P C;  4L10 C;  4HLM C;  5ADT B;  5C5R C;  4HLF C;  4HMH C;  4KZU C;  4HLK C;  4L33 C;  4HKK B;  4UI5 C; 
#chains in the Genus database with same CATH topology
 4L32 C;  3OEI E;  4L31 C;  3OEI A;  4UI4 C;  3D55 A;  5ADR B;  4L0I C;  5C5Q C;  3K6Q A;  4UVP B;  4KZL C;  4HKI C;  4UI7 C;  3HRY A;  3G5O A;  4L0T C;  4L09 C;  4L33 C;  5ADQ B;  4HKK B;  4HLG C;  4KZQ C;  5FPF C;  4ZM0 A;  4HL5 C;  4HLH C;  4L0V C;  4L2K C;  4L34 C;  4ZM2 A;  4HKN C;  4UI3 C;  4UI8 C;  4L0B C;  4L0S C;  4UI6 C;  2ZIX B;  2A6Q A;  4L2G C;  4L2F C;  5ADS B;  5C5P C;  4L10 C;  3K33 B;  4HLM C;  5ADT B;  5C5R C;  4HLF C;  3KH2 E;  3HJ6 A;  4HMH C;  4KZU C;  3CTO A;  4HLK C;  2ODK A;  3HS2 A;  4ZLX A;  4UI5 C; 
#chains in the Genus database with same CATH homology
 4L32 C;  4L31 C;  4UI4 C;  5ADR B;  4L0I C;  5C5Q C;  4UVP B;  4KZL C;  4HKI C;  4UI7 C;  4L0T C;  4L09 C;  5ADQ B;  4HLG C;  4KZQ C;  5FPF C;  4HL5 C;  4L0V C;  4HLH C;  4L2K C;  4L34 C;  4HKN C;  4UI3 C;  4UI8 C;  4L0B C;  4L0S C;  4UI6 C;  2ZIX B;  4L2G C;  4L2F C;  5ADS B;  5C5P C;  4L10 C;  4HLM C;  5ADT B;  5C5R C;  4HLF C;  3HJ6 A;  4HMH C;  4KZU C;  4HLK C;  4L33 C;  4HKK B;  4UI5 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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