5FPFC

Crystal structure of human tankyrase 2 in complex with ta-91
Total Genus 0
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
0
sequence length
46
structure length
46
Chain Sequence
AHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
molecule keywords TANKYRASE-2
publication title Design, Synthesis and Evaluation of Novel Dual- Binding Inhibitors of the Tankyrases and Wnt Signalling.
rcsb
source organism Homo sapiens
structure length 46
sequence length 46
chains with identical sequence D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-11-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1620.50 Alpha Beta 3-Layer(aba) Sandwich YefM-like fold YefM-like fold 5fpfC00
5ADTB 4L31C 5FPFC 4L0BC 4HL5C 4UI5C 4L33C 4UI4C 4L32C 4L10C 5ADSB 4HKNC 4L2GC 5C5QC 4KZQC 4L34C 4HLGC 4L2FC 5ADQB 4KZLC 5C5RC 4HLKC 4HKIC 4L0TC 4KZUC 4L0VC 4HLFC 4L09C 4HKKB 4UI8C 5ADRB 4UI7C 4HMHC 5C5PC 4L0SC 4HLMC 4UI6C 4UI3C 4L0IC 4L2KC 4HLHC 4UVPB
chains in the Genus database with same CATH superfamily
5ADTB 4L31C 5FPFC 3K33B 4L0BC 4HL5C 2ODKA 4UI5C 4L33C 4UI4C 4L32C 4L10C 5ADSB 4HKNC 4L2GC 5C5QC 3HJ6A 4KZQC 4L34C 4HLGC 4L2FC 5ADQB 3G5OA 4KZLC 5C5RC 4HLKC 4HKIC 3CTOA 3K6QA 4L0TC 4KZUC 2A6QA 3HS2A 4L0VC 4HLFC 4L09C 4HKKB 4UI8C 5ADRB 4ZM2A 3D55A 3KH2E 4UI7C 4ZM0A 4HMHC 5C5PC 3OEIE 3HRYA 4HLMC 4L0SC 4UI6C 3OEIA 4UI3C 2ZIXB 4L0IC 4L2KC 4ZLXA 4HLHC 4UVPB
chains in the Genus database with same CATH topology
5ADTB 4L31C 5FPFC 4L0BC 4HL5C 4UI5C 4L33C 4UI4C 4L32C 4L10C 5ADSB 4HKNC 4L2GC 5C5QC 3HJ6A 4KZQC 4L34C 4HLGC 4L2FC 5ADQB 4KZLC 5C5RC 4HLKC 4HKIC 4L0TC 4KZUC 4L0VC 4HLFC 4L09C 4HKKB 4UI8C 5ADRB 4UI7C 4HMHC 5C5PC 4L0SC 4HLMC 4UI6C 4UI3C 2ZIXB 4L0IC 4L2KC 4HLHC 4UVPB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ADT B;  4L31 C;  5FPF C;  4L0B C;  4HL5 C;  4UI5 C;  4L33 C;  4UI4 C;  4L32 C;  4L10 C;  5ADS B;  4HKN C;  4L2G C;  5C5Q C;  4KZQ C;  4L34 C;  4HLG C;  4L2F C;  5ADQ B;  4KZL C;  5C5R C;  4HLK C;  4HKI C;  4L0T C;  4KZU C;  4L0V C;  4HLF C;  4L09 C;  4HKK B;  4UI8 C;  5ADR B;  4UI7 C;  4HMH C;  5C5P C;  4L0S C;  4HLM C;  4UI6 C;  4UI3 C;  4L0I C;  4L2K C;  4HLH C;  4UVP B; 
#chains in the Genus database with same CATH topology
 5ADT B;  4L31 C;  5FPF C;  3K33 B;  4L0B C;  4HL5 C;  2ODK A;  4UI5 C;  4L33 C;  4UI4 C;  4L32 C;  4L10 C;  5ADS B;  4HKN C;  4L2G C;  5C5Q C;  3HJ6 A;  4KZQ C;  4L34 C;  4HLG C;  4L2F C;  5ADQ B;  3G5O A;  4KZL C;  5C5R C;  4HLK C;  4HKI C;  3CTO A;  3K6Q A;  4L0T C;  4KZU C;  2A6Q A;  3HS2 A;  4L0V C;  4HLF C;  4L09 C;  4HKK B;  4UI8 C;  5ADR B;  4ZM2 A;  3D55 A;  3KH2 E;  4UI7 C;  4ZM0 A;  4HMH C;  5C5P C;  3OEI E;  3HRY A;  4HLM C;  4L0S C;  4UI6 C;  3OEI A;  4UI3 C;  2ZIX B;  4L0I C;  4L2K C;  4ZLX A;  4HLH C;  4UVP B; 
#chains in the Genus database with same CATH homology
 5ADT B;  4L31 C;  5FPF C;  4L0B C;  4HL5 C;  4UI5 C;  4L33 C;  4UI4 C;  4L32 C;  4L10 C;  5ADS B;  4HKN C;  4L2G C;  5C5Q C;  3HJ6 A;  4KZQ C;  4L34 C;  4HLG C;  4L2F C;  5ADQ B;  4KZL C;  5C5R C;  4HLK C;  4HKI C;  4L0T C;  4KZU C;  4L0V C;  4HLF C;  4L09 C;  4HKK B;  4UI8 C;  5ADR B;  4UI7 C;  4HMH C;  5C5P C;  4L0S C;  4HLM C;  4UI6 C;  4UI3 C;  2ZIX B;  4L0I C;  4L2K C;  4HLH C;  4UVP B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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