4CNE | Genus

Total Genus 56

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	56
Knots found	KnotProt 2.0: K +3₁
sequence length	169
structure length	169
Chain Sequence	DPALRALQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 169 atoms

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169 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates. pubmed doi rcsb
molecule keywords	TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
molecule tags	Transferase
source organism	Escherichia coli
total genus	56
structure length	169
sequence length	169
chains with identical sequence	B
other databases	KnotProt 2.0: K +3₁
ec nomenclature	ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date	2014-01-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00588	SpoU_methylase	SpoU rRNA Methylase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1280.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	4cneA01

1MXIA 3ONPA 2V3JA 2V3KA 3AXZA 2QMMA 4YPXA 4H3YA 2O3AA 3KY7A 4YQNA 3N4JA 3DCMX 1OY5A 4YVHA 1Z85A 3AIAA 2HA8A 3NK6A 4JALA 4YQOA 1V6ZA 1NXZA 3KW2A 4YQ4A 1VHYA 3GYQA 4YQKA 5FAIA 4FAKA 4XBOA 5GMCA 1ZJRA 4YQ8A 4YQJA 4YQ9A 3AI9X 1K3RA 4J3CA 4YVGA 4YQ3A 4CNEA 4YQGA 1IPAA 3BBHA 4CNFA 2QWVA 3IEFA 3ILKA 4YQRA 3IC6A 3QUVA 4YQDA 3O7BA 4IG6A 4YQ7A 1VH0A 4YQ1A 1GZ0A 3N4KA 4X3MA 1X7OA 3OINA 2YY8A 3L8UA 5GMBA 1VHKA 4YQQA 1P9PA 1X7PA 4MCDA 1UALA 4YQPA 4MCBA 4X3LA 3KTYA 2EGVA 3OIJA 5GM8A 4YQ6A 4CNDA 4YVKA 4YQ0A 1V2XA 4YQSA 3BBEA 1UAJA 4L69A 3OIIA 2EGWA 4MCCA 5CO4A 1J85A 4YPZA 1UAMA 4RG1A 4CNGA 1O6DA 4KGNA 1NS5A 4YQCA 4YVJA 1UAKA 2Z0YA 3BBDA 4YQ5A 4YQAA 2I6DA 4YQIA 4YQBA 5D9FA 4YVIA 4YQTA 2CX8A 4YPWA 4JAKA 4H3ZA 1TO0A 4E8BA 3NK7A 3KNUA 4KDZA 3E5YA 4YPYA 4PZKA 4YQLA 4YQ2A
chains in the Genus database with same CATH superfamily

1MXIA 3ONPA 2V3JA 2V3KA 3AXZA 2QMMA 4YPXA 4H3YA 2O3AA 3KY7A 4YQNA 3N4JA 3DCMX 1OY5A 4YVHA 1Z85A 3AIAA 2HA8A 3NK6A 4JALA 4YQOA 1V6ZA 1NXZA 3KW2A 4YQ4A 1VHYA 3GYQA 4YQKA 5FAIA 4FAKA 4XBOA 5GMCA 1ZJRA 4YQ8A 4YQJA 4YQ9A 3AI9X 1K3RA 4J3CA 4YVGA 4YQ3A 4CNEA 4YQGA 1IPAA 3BBHA 4CNFA 2QWVA 3IEFA 3ILKA 4YQRA 3IC6A 3QUVA 4YQDA 3O7BA 4IG6A 4YQ7A 1VH0A 4YQ1A 1GZ0A 3N4KA 4X3MA 1X7OA 4JWJA 3OINA 2YY8A 3L8UA 5GMBA 1VHKA 4YQQA 1P9PA 1X7PA 4MCDA 1UALA 4YQPA 4MCBA 4JWGA 4X3LA 3KTYA 4JWHA 2EGVA 3OIJA 5GM8A 4YQ6A 4CNDA 4YVKA 4YQ0A 1V2XA 4YQSA 3BBEA 1UAJA 4L69A 3OIIA 2EGWA 4MCCA 5CO4A 1J85A 4FMWA 4YPZA 1UAMA 4RG1A 4CNGA 1O6DA 4KGNA 1NS5A 4YQCA 4YVJA 1UAKA 2Z0YA 3BBDA 4YQ5A 4YQAA 2I6DA 4YQIA 4JWFA 4YQBA 5D9FA 4YVIA 4YQTA 2CX8A 4YPWA 4JAKA 4H3ZA 1TO0A 4E8BA 3NK7A 3KNUA 4KDZA 3E5YA 4YPYA 4PZKA 4YQLA 4YQ2A
chains in the Genus database with same CATH topology

1MXIA 3ONPA 2V3JA 2V3KA 3AXZA 2QMMA 4YPXA 4H3YA 2O3AA 3KY7A 4YQNA 3N4JA 3DCMX 1OY5A 4YVHA 1Z85A 3AIAA 2HA8A 3NK6A 4JALA 4YQOA 1V6ZA 1NXZA 3KW2A 4YQ4A 1VHYA 3GYQA 4YQKA 5FAIA 4FAKA 4XBOA 5GMCA 1ZJRA 4YQ8A 4YQJA 4YQ9A 3AI9X 1K3RA 4J3CA 4YVGA 4YQ3A 4CNEA 4YQGA 1IPAA 3BBHA 4CNFA 2QWVA 3IEFA 3ILKA 4YQRA 3IC6A 3QUVA 4YQDA 3O7BA 4IG6A 4YQ7A 1VH0A 4YQ1A 1GZ0A 3N4KA 4X3MA 1X7OA 4JWJA 3OINA 2YY8A 3L8UA 5GMBA 1VHKA 4YQQA 1P9PA 1X7PA 4MCDA 1UALA 4YQPA 4MCBA 4JWGA 4X3LA 3KTYA 4JWHA 2EGVA 3OIJA 5GM8A 4YQ6A 4CNDA 4YVKA 4YQ0A 1V2XA 4YQSA 3BBEA 1UAJA 4L69A 3OIIA 2EGWA 4MCCA 5CO4A 1J85A 4FMWA 4YPZA 1UAMA 4RG1A 4CNGA 1O6DA 4KGNA 1NS5A 4YQCA 4YVJA 1UAKA 2Z0YA 3BBDA 4YQ5A 4YQAA 2I6DA 4YQIA 4JWFA 4YQBA 5D9FA 4YVIA 4YQTA 2CX8A 4YPWA 4JAKA 4H3ZA 1TO0A 4E8BA 3NK7A 3KNUA 4KDZA 3E5YA 4YPYA 4PZKA 4YQLA 4YQ2A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1MXI A;  3ONP A;  2V3J A;  2V3K A;  3AXZ A;  2QMM A;  4YPX A;  4H3Y A;  2O3A A;  3KY7 A;  4YQN A;  3N4J A;  3DCM X;  1OY5 A;  4YVH A;  1Z85 A;  3AIA A;  2HA8 A;  3NK6 A;  4JAL A;  4YQO A;  1V6Z A;  1NXZ A;  3KW2 A;  4YQ4 A;  1VHY A;  3GYQ A;  4YQK A;  5FAI A;  4FAK A;  4XBO A;  5GMC A;  1ZJR A;  4YQ8 A;  4YQJ A;  4YQ9 A;  3AI9 X;  1K3R A;  4J3C A;  4YVG A;  4YQ3 A;  4CNE A;  4YQG A;  1IPA A;  3BBH A;  4CNF A;  2QWV A;  3IEF A;  3ILK A;  4YQR A;  3IC6 A;  3QUV A;  4YQD A;  3O7B A;  4IG6 A;  4YQ7 A;  1VH0 A;  4YQ1 A;  1GZ0 A;  3N4K A;  4X3M A;  1X7O A;  3OIN A;  2YY8 A;  3L8U A;  5GMB A;  1VHK A;  4YQQ A;  1P9P A;  1X7P A;  4MCD A;  1UAL A;  4YQP A;  4MCB A;  4X3L A;  3KTY A;  2EGV A;  3OIJ A;  5GM8 A;  4YQ6 A;  4CND A;  4YVK A;  4YQ0 A;  1V2X A;  4YQS A;  3BBE A;  1UAJ A;  4L69 A;  3OII A;  2EGW A;  4MCC A;  5CO4 A;  1J85 A;  4YPZ A;  1UAM A;  4RG1 A;  4CNG A;  1O6D A;  4KGN A;  1NS5 A;  4YQC A;  4YVJ A;  1UAK A;  2Z0Y A;  3BBD A;  4YQ5 A;  4YQA A;  2I6D A;  4YQI A;  4YQB A;  5D9F A;  4YVI A;  4YQT A;  2CX8 A;  4YPW A;  4JAK A;  4H3Z A;  1TO0 A;  4E8B A;  3NK7 A;  3KNU A;  4KDZ A;  3E5Y A;  4YPY A;  4PZK A;  4YQL A;  4YQ2 A; 
#chains in the Genus database with same CATH topology
 1MXI A;  3ONP A;  2V3J A;  2V3K A;  3AXZ A;  2QMM A;  4YPX A;  4H3Y A;  2O3A A;  3KY7 A;  4YQN A;  3N4J A;  3DCM X;  1OY5 A;  4YVH A;  1Z85 A;  3AIA A;  2HA8 A;  3NK6 A;  4JAL A;  4YQO A;  1V6Z A;  1NXZ A;  3KW2 A;  4YQ4 A;  1VHY A;  3GYQ A;  4YQK A;  5FAI A;  4FAK A;  4XBO A;  5GMC A;  1ZJR A;  4YQ8 A;  4YQJ A;  4YQ9 A;  3AI9 X;  1K3R A;  4J3C A;  4YVG A;  4YQ3 A;  4CNE A;  4YQG A;  1IPA A;  3BBH A;  4CNF A;  2QWV A;  3IEF A;  3ILK A;  4YQR A;  3IC6 A;  3QUV A;  4YQD A;  3O7B A;  4IG6 A;  4YQ7 A;  1VH0 A;  4YQ1 A;  1GZ0 A;  3N4K A;  4X3M A;  1X7O A;  4JWJ A;  3OIN A;  2YY8 A;  3L8U A;  5GMB A;  1VHK A;  4YQQ A;  1P9P A;  1X7P A;  4MCD A;  1UAL A;  4YQP A;  4MCB A;  4JWG A;  4X3L A;  3KTY A;  4JWH A;  2EGV A;  3OIJ A;  5GM8 A;  4YQ6 A;  4CND A;  4YVK A;  4YQ0 A;  1V2X A;  4YQS A;  3BBE A;  1UAJ A;  4L69 A;  3OII A;  2EGW A;  4MCC A;  5CO4 A;  1J85 A;  4FMW A;  4YPZ A;  1UAM A;  4RG1 A;  4CNG A;  1O6D A;  4KGN A;  1NS5 A;  4YQC A;  4YVJ A;  1UAK A;  2Z0Y A;  3BBD A;  4YQ5 A;  4YQA A;  2I6D A;  4YQI A;  4JWF A;  4YQB A;  5D9F A;  4YVI A;  4YQT A;  2CX8 A;  4YPW A;  4JAK A;  4H3Z A;  1TO0 A;  4E8B A;  3NK7 A;  3KNU A;  4KDZ A;  3E5Y A;  4YPY A;  4PZK A;  4YQL A;  4YQ2 A; 
#chains in the Genus database with same CATH homology
 1MXI A;  3ONP A;  2V3J A;  2V3K A;  3AXZ A;  2QMM A;  4YPX A;  4H3Y A;  2O3A A;  3KY7 A;  4YQN A;  3N4J A;  3DCM X;  1OY5 A;  4YVH A;  1Z85 A;  3AIA A;  2HA8 A;  3NK6 A;  4JAL A;  4YQO A;  1V6Z A;  1NXZ A;  3KW2 A;  4YQ4 A;  1VHY A;  3GYQ A;  4YQK A;  5FAI A;  4FAK A;  4XBO A;  5GMC A;  1ZJR A;  4YQ8 A;  4YQJ A;  4YQ9 A;  3AI9 X;  1K3R A;  4J3C A;  4YVG A;  4YQ3 A;  4CNE A;  4YQG A;  1IPA A;  3BBH A;  4CNF A;  2QWV A;  3IEF A;  3ILK A;  4YQR A;  3IC6 A;  3QUV A;  4YQD A;  3O7B A;  4IG6 A;  4YQ7 A;  1VH0 A;  4YQ1 A;  1GZ0 A;  3N4K A;  4X3M A;  1X7O A;  4JWJ A;  3OIN A;  2YY8 A;  3L8U A;  5GMB A;  1VHK A;  4YQQ A;  1P9P A;  1X7P A;  4MCD A;  1UAL A;  4YQP A;  4MCB A;  4JWG A;  4X3L A;  3KTY A;  4JWH A;  2EGV A;  3OIJ A;  5GM8 A;  4YQ6 A;  4CND A;  4YVK A;  4YQ0 A;  1V2X A;  4YQS A;  3BBE A;  1UAJ A;  4L69 A;  3OII A;  2EGW A;  4MCC A;  5CO4 A;  1J85 A;  4FMW A;  4YPZ A;  1UAM A;  4RG1 A;  4CNG A;  1O6D A;  4KGN A;  1NS5 A;  4YQC A;  4YVJ A;  1UAK A;  2Z0Y A;  3BBD A;  4YQ5 A;  4YQA A;  2I6D A;  4YQI A;  4JWF A;  4YQB A;  5D9F A;  4YVI A;  4YQT A;  2CX8 A;  4YPW A;  4JAK A;  4H3Z A;  1TO0 A;  4E8B A;  3NK7 A;  3KNU A;  4KDZ A;  3E5Y A;  4YPY A;  4PZK A;  4YQL A;  4YQ2 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4CNEA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations