4CNEA

Crystal structure of e.coli trmj in complex with s-adenosyl-l- homocysteine
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
Knots found
sequence length
169
structure length
169
Chain Sequence
DPALRALQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLATQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords TRNA (CYTIDINE/URIDINE-2'-O-)-METHYLTRANSFERASE TRMJ
total genus 56
structure length 169
sequence length 169
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cneA01
2HA8A 2EGWA 1NXZA 4E8BA 1O6DA 4YQ2A 4YQ0A 2V3KA 4MCDA 4YPZA 4YVHA 1NS5A 2YY8A 3AXZA 1UAMA 4IG6A 3NK6A 2I6DA 3IC6A 4YQ9A 3L8UA 4CNDA 3OIIA 4YQ1A 3IEFA 4YQ5A 2V3JA 1MXIA 1J85A 4YPXA 4J3CA 1X7OA 5CO4A 4XBOA 4YQKA 4KGNA 5GMCA 3E5YA 4YQLA 1V6ZA 4YQ7A 3GYQA 3QUVA 4YQBA 4YQNA 4YVJA 4YQTA 4YQ3A 2Z0YA 4YQGA 3OINA 4L69A 1GZ0A 3OIJA 4YVGA 1ZJRA 3NK7A 3N4KA 3BBHA 2QWVA 4YPYA 3AIAA 4H3ZA 2O3AA 3BBDA 4YQSA 1TO0A 4MCCA 3AI9X 1X7PA 3DCMX 4YVIA 4PZKA 3N4JA 5FAIA 4YQ4A 1P9PA 1Z85A 4YQ6A 4YQJA 3KW2A 4CNFA 5GM8A 4CNGA 4YQ8A 2EGVA 4YVKA 2CX8A 4X3LA 4KDZA 1VHYA 4X3MA 4YQDA 3ILKA 4YQCA 3O7BA 1K3RA 4YQOA 3BBEA 4CNEA 3ONPA 1V2XA 3KNUA 1UAJA 1IPAA 4MCBA 4YPWA 1OY5A 1VHKA 3KTYA 4YQIA 3KY7A 4YQAA 4YQPA 4RG1A 5GMBA 1UALA 4JAKA 5D9FA 1VH0A 4H3YA 4FAKA 4YQRA 4YQQA 2QMMA 1UAKA 4JALA
chains in the Genus database with same CATH superfamily
2HA8A 2EGWA 1NXZA 4E8BA 1O6DA 4YQ2A 4YQ0A 2V3KA 4MCDA 4YPZA 4YVHA 1NS5A 2YY8A 3AXZA 1UAMA 4IG6A 3NK6A 2I6DA 3IC6A 4YQ9A 3L8UA 4CNDA 3OIIA 4YQ1A 3IEFA 4YQ5A 2V3JA 1MXIA 1J85A 4YPXA 4J3CA 1X7OA 5CO4A 4XBOA 4YQKA 4KGNA 5GMCA 3E5YA 4JWJA 4YQLA 1V6ZA 4YQ7A 3GYQA 3QUVA 4YQBA 4YQNA 4YVJA 4YQTA 4YQ3A 2Z0YA 4YQGA 3OINA 4L69A 1GZ0A 3OIJA 4YVGA 1ZJRA 3NK7A 4JWGA 3N4KA 3BBHA 2QWVA 4YPYA 3AIAA 4H3ZA 2O3AA 3BBDA 4YQSA 1TO0A 4MCCA 3AI9X 1X7PA 3DCMX 4YVIA 4PZKA 3N4JA 5FAIA 4YQ4A 1P9PA 1Z85A 4YQ6A 4YQJA 3KW2A 4CNFA 5GM8A 4CNGA 4YQ8A 2EGVA 4YVKA 2CX8A 4X3LA 4KDZA 1VHYA 4X3MA 4YQDA 3ILKA 4YQCA 3O7BA 1K3RA 4JWFA 4YQOA 3BBEA 4CNEA 3ONPA 1V2XA 3KNUA 1UAJA 1IPAA 4MCBA 4YPWA 1OY5A 1VHKA 3KTYA 4YQIA 3KY7A 4YQAA 4YQPA 4JWHA 4RG1A 5GMBA 1UALA 4JAKA 5D9FA 4FMWA 1VH0A 4H3YA 4FAKA 4YQRA 4YQQA 2QMMA 1UAKA 4JALA
chains in the Genus database with same CATH topology
2HA8A 2EGWA 1NXZA 4E8BA 1O6DA 4YQ2A 4YQ0A 2V3KA 4MCDA 4YPZA 4YVHA 1NS5A 2YY8A 3AXZA 1UAMA 4IG6A 3NK6A 2I6DA 3IC6A 4YQ9A 3L8UA 4CNDA 3OIIA 4YQ1A 3IEFA 4YQ5A 2V3JA 1MXIA 1J85A 4YPXA 4J3CA 1X7OA 5CO4A 4XBOA 4YQKA 4KGNA 5GMCA 3E5YA 4JWJA 4YQLA 1V6ZA 4YQ7A 3GYQA 3QUVA 4YQBA 4YQNA 4YVJA 4YQTA 4YQ3A 2Z0YA 4YQGA 3OINA 4L69A 1GZ0A 3OIJA 4YVGA 1ZJRA 3NK7A 4JWGA 3N4KA 3BBHA 2QWVA 4YPYA 3AIAA 4H3ZA 2O3AA 3BBDA 4YQSA 1TO0A 4MCCA 3AI9X 1X7PA 3DCMX 4YVIA 4PZKA 3N4JA 5FAIA 4YQ4A 1P9PA 1Z85A 4YQ6A 4YQJA 3KW2A 4CNFA 5GM8A 4CNGA 4YQ8A 2EGVA 4YVKA 2CX8A 4X3LA 4KDZA 1VHYA 4X3MA 4YQDA 3ILKA 4YQCA 3O7BA 1K3RA 4JWFA 4YQOA 3BBEA 4CNEA 3ONPA 1V2XA 3KNUA 1UAJA 1IPAA 4MCBA 4YPWA 1OY5A 1VHKA 3KTYA 4YQIA 3KY7A 4YQAA 4YQPA 4JWHA 4RG1A 5GMBA 1UALA 4JAKA 5D9FA 4FMWA 1VH0A 4H3YA 4FAKA 4YQRA 4YQQA 2QMMA 1UAKA 4JALA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HA8 A;  2EGW A;  1NXZ A;  4E8B A;  1O6D A;  4YQ2 A;  4YQ0 A;  2V3K A;  4MCD A;  4YPZ A;  4YVH A;  1NS5 A;  2YY8 A;  3AXZ A;  1UAM A;  4IG6 A;  3NK6 A;  2I6D A;  3IC6 A;  4YQ9 A;  3L8U A;  4CND A;  3OII A;  4YQ1 A;  3IEF A;  4YQ5 A;  2V3J A;  1MXI A;  1J85 A;  4YPX A;  4J3C A;  1X7O A;  5CO4 A;  4XBO A;  4YQK A;  4KGN A;  5GMC A;  3E5Y A;  4YQL A;  1V6Z A;  4YQ7 A;  3GYQ A;  3QUV A;  4YQB A;  4YQN A;  4YVJ A;  4YQT A;  4YQ3 A;  2Z0Y A;  4YQG A;  3OIN A;  4L69 A;  1GZ0 A;  3OIJ A;  4YVG A;  1ZJR A;  3NK7 A;  3N4K A;  3BBH A;  2QWV A;  4YPY A;  3AIA A;  4H3Z A;  2O3A A;  3BBD A;  4YQS A;  1TO0 A;  4MCC A;  3AI9 X;  1X7P A;  3DCM X;  4YVI A;  4PZK A;  3N4J A;  5FAI A;  4YQ4 A;  1P9P A;  1Z85 A;  4YQ6 A;  4YQJ A;  3KW2 A;  4CNF A;  5GM8 A;  4CNG A;  4YQ8 A;  2EGV A;  4YVK A;  2CX8 A;  4X3L A;  4KDZ A;  1VHY A;  4X3M A;  4YQD A;  3ILK A;  4YQC A;  3O7B A;  1K3R A;  4YQO A;  3BBE A;  4CNE A;  3ONP A;  1V2X A;  3KNU A;  1UAJ A;  1IPA A;  4MCB A;  4YPW A;  1OY5 A;  1VHK A;  3KTY A;  4YQI A;  3KY7 A;  4YQA A;  4YQP A;  4RG1 A;  5GMB A;  1UAL A;  4JAK A;  5D9F A;  1VH0 A;  4H3Y A;  4FAK A;  4YQR A;  4YQQ A;  2QMM A;  1UAK A;  4JAL A; 
#chains in the Genus database with same CATH topology
 2HA8 A;  2EGW A;  1NXZ A;  4E8B A;  1O6D A;  4YQ2 A;  4YQ0 A;  2V3K A;  4MCD A;  4YPZ A;  4YVH A;  1NS5 A;  2YY8 A;  3AXZ A;  1UAM A;  4IG6 A;  3NK6 A;  2I6D A;  3IC6 A;  4YQ9 A;  3L8U A;  4CND A;  3OII A;  4YQ1 A;  3IEF A;  4YQ5 A;  2V3J A;  1MXI A;  1J85 A;  4YPX A;  4J3C A;  1X7O A;  5CO4 A;  4XBO A;  4YQK A;  4KGN A;  5GMC A;  3E5Y A;  4JWJ A;  4YQL A;  1V6Z A;  4YQ7 A;  3GYQ A;  3QUV A;  4YQB A;  4YQN A;  4YVJ A;  4YQT A;  4YQ3 A;  2Z0Y A;  4YQG A;  3OIN A;  4L69 A;  1GZ0 A;  3OIJ A;  4YVG A;  1ZJR A;  3NK7 A;  4JWG A;  3N4K A;  3BBH A;  2QWV A;  4YPY A;  3AIA A;  4H3Z A;  2O3A A;  3BBD A;  4YQS A;  1TO0 A;  4MCC A;  3AI9 X;  1X7P A;  3DCM X;  4YVI A;  4PZK A;  3N4J A;  5FAI A;  4YQ4 A;  1P9P A;  1Z85 A;  4YQ6 A;  4YQJ A;  3KW2 A;  4CNF A;  5GM8 A;  4CNG A;  4YQ8 A;  2EGV A;  4YVK A;  2CX8 A;  4X3L A;  4KDZ A;  1VHY A;  4X3M A;  4YQD A;  3ILK A;  4YQC A;  3O7B A;  1K3R A;  4JWF A;  4YQO A;  3BBE A;  4CNE A;  3ONP A;  1V2X A;  3KNU A;  1UAJ A;  1IPA A;  4MCB A;  4YPW A;  1OY5 A;  1VHK A;  3KTY A;  4YQI A;  3KY7 A;  4YQA A;  4YQP A;  4JWH A;  4RG1 A;  5GMB A;  1UAL A;  4JAK A;  5D9F A;  4FMW A;  1VH0 A;  4H3Y A;  4FAK A;  4YQR A;  4YQQ A;  2QMM A;  1UAK A;  4JAL A; 
#chains in the Genus database with same CATH homology
 2HA8 A;  2EGW A;  1NXZ A;  4E8B A;  1O6D A;  4YQ2 A;  4YQ0 A;  2V3K A;  4MCD A;  4YPZ A;  4YVH A;  1NS5 A;  2YY8 A;  3AXZ A;  1UAM A;  4IG6 A;  3NK6 A;  2I6D A;  3IC6 A;  4YQ9 A;  3L8U A;  4CND A;  3OII A;  4YQ1 A;  3IEF A;  4YQ5 A;  2V3J A;  1MXI A;  1J85 A;  4YPX A;  4J3C A;  1X7O A;  5CO4 A;  4XBO A;  4YQK A;  4KGN A;  5GMC A;  3E5Y A;  4JWJ A;  4YQL A;  1V6Z A;  4YQ7 A;  3GYQ A;  3QUV A;  4YQB A;  4YQN A;  4YVJ A;  4YQT A;  4YQ3 A;  2Z0Y A;  4YQG A;  3OIN A;  4L69 A;  1GZ0 A;  3OIJ A;  4YVG A;  1ZJR A;  3NK7 A;  4JWG A;  3N4K A;  3BBH A;  2QWV A;  4YPY A;  3AIA A;  4H3Z A;  2O3A A;  3BBD A;  4YQS A;  1TO0 A;  4MCC A;  3AI9 X;  1X7P A;  3DCM X;  4YVI A;  4PZK A;  3N4J A;  5FAI A;  4YQ4 A;  1P9P A;  1Z85 A;  4YQ6 A;  4YQJ A;  3KW2 A;  4CNF A;  5GM8 A;  4CNG A;  4YQ8 A;  2EGV A;  4YVK A;  2CX8 A;  4X3L A;  4KDZ A;  1VHY A;  4X3M A;  4YQD A;  3ILK A;  4YQC A;  3O7B A;  1K3R A;  4JWF A;  4YQO A;  3BBE A;  4CNE A;  3ONP A;  1V2X A;  3KNU A;  1UAJ A;  1IPA A;  4MCB A;  4YPW A;  1OY5 A;  1VHK A;  3KTY A;  4YQI A;  3KY7 A;  4YQA A;  4YQP A;  4JWH A;  4RG1 A;  5GMB A;  1UAL A;  4JAK A;  5D9F A;  4FMW A;  1VH0 A;  4H3Y A;  4FAK A;  4YQR A;  4YQQ A;  2QMM A;  1UAK A;  4JAL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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