4CNF | Genus

Total Genus 47

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	47
Knots found	KnotProt 2.0: K +3₁
sequence length	157
structure length	155
Chain Sequence	MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKGSEVIEKMMKITNNFDDAIRDVDLKIATSSIADGDLLRKSIRPIDLERLIKDKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRNR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 155 atoms

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155 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates. pubmed doi rcsb
molecule keywords	SPOU RRNA METHYLASE
molecule tags	Transferase
source organism	Sulfolobus acidocaldarius
total genus	47
structure length	155
sequence length	157
chains with identical sequence	B
other databases	KnotProt 2.0: K +3₁
ec nomenclature	ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date	2014-01-22

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00588	SpoU_methylase	SpoU rRNA Methylase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1280.10	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	4cnfA00

1VHYA 4L69A 4YQ5A 1NS5A 1UAJA 1V2XA 4FAKA 3KNUA 2CX8A 2QMMA 3OIJA 3BBEA 4MCCA 5FAIA 3ILKA 2QWVA 3E5YA 4YQ2A 2V3JA 3O7BA 4JAKA 5CO4A 1NXZA 4YQQA 4YVGA 3ONPA 4J3CA 3AXZA 2YY8A 1UALA 4PZKA 4YQIA 4YPXA 4CNGA 3BBDA 4YQ1A 1X7PA 2I6DA 4YQ3A 3KTYA 4YQ4A 4XBOA 4IG6A 5GM8A 3DCMX 4YQLA 4X3LA 4CNFA 5GMBA 4H3ZA 4E8BA 1UAMA 1GZ0A 3N4JA 4YQGA 4YVKA 4H3YA 1K3RA 5GMCA 4YQAA 3OINA 3AIAA 4YQDA 1P9PA 1Z85A 2HA8A 4YPYA 4YQ9A 4CNDA 4YPZA 4JALA 2V3KA 3N4KA 4YQ6A 4YQTA 1J85A 4YQOA 1O6DA 1X7OA 4YQ8A 4YQSA 1UAKA 4YVIA 3KW2A 3OIIA 4YQRA 1ZJRA 2EGVA 4YQ7A 2Z0YA 4MCBA 4MCDA 1VHKA 2O3AA 3NK7A 4RG1A 1MXIA 4YQJA 1OY5A 4YQPA 3L8UA 4CNEA 4YQCA 3IC6A 3BBHA 3IEFA 1IPAA 4YQNA 4KGNA 1V6ZA 3NK6A 2EGWA 4YVJA 4YPWA 3KY7A 1VH0A 3QUVA 5D9FA 3AI9X 4X3MA 4YQBA 4KDZA 3GYQA 4YQ0A 4YQKA 4YVHA 1TO0A
chains in the Genus database with same CATH superfamily

1VHYA 4L69A 4YQ5A 1NS5A 1UAJA 1V2XA 4FAKA 3KNUA 2CX8A 2QMMA 3OIJA 3BBEA 4MCCA 5FAIA 3ILKA 2QWVA 3E5YA 4YQ2A 2V3JA 3O7BA 4JAKA 5CO4A 1NXZA 4YQQA 4YVGA 3ONPA 4J3CA 3AXZA 2YY8A 1UALA 4PZKA 4YQIA 4JWGA 4YPXA 4CNGA 3BBDA 4YQ1A 1X7PA 2I6DA 4YQ3A 3KTYA 4YQ4A 4XBOA 4IG6A 5GM8A 3DCMX 4YQLA 4X3LA 4CNFA 5GMBA 4H3ZA 4E8BA 1UAMA 1GZ0A 3N4JA 4YQGA 4YVKA 4H3YA 1K3RA 5GMCA 4YQAA 4FMWA 3OINA 3AIAA 4YQDA 1P9PA 1Z85A 2HA8A 4YPYA 4YQ9A 4CNDA 4YPZA 4JALA 2V3KA 3N4KA 4YQ6A 4YQTA 1J85A 4YQOA 1O6DA 1X7OA 4YQ8A 4JWFA 4YQSA 1UAKA 4YVIA 3KW2A 4JWHA 3OIIA 4YQRA 1ZJRA 2EGVA 4YQ7A 2Z0YA 4MCBA 4MCDA 1VHKA 2O3AA 3NK7A 4RG1A 1MXIA 4YQJA 1OY5A 4YQPA 3L8UA 4CNEA 4YQCA 3IC6A 3BBHA 3IEFA 1IPAA 4JWJA 4YQNA 4KGNA 1V6ZA 3NK6A 2EGWA 4YVJA 4YPWA 3KY7A 1VH0A 3QUVA 5D9FA 3AI9X 4X3MA 4YQBA 4KDZA 3GYQA 4YQ0A 4YQKA 4YVHA 1TO0A
chains in the Genus database with same CATH topology

1VHYA 4L69A 4YQ5A 1NS5A 1UAJA 1V2XA 4FAKA 3KNUA 2CX8A 2QMMA 3OIJA 3BBEA 4MCCA 5FAIA 3ILKA 2QWVA 3E5YA 4YQ2A 2V3JA 3O7BA 4JAKA 5CO4A 1NXZA 4YQQA 4YVGA 3ONPA 4J3CA 3AXZA 2YY8A 1UALA 4PZKA 4YQIA 4JWGA 4YPXA 4CNGA 3BBDA 4YQ1A 1X7PA 2I6DA 4YQ3A 3KTYA 4YQ4A 4XBOA 4IG6A 5GM8A 3DCMX 4YQLA 4X3LA 4CNFA 5GMBA 4H3ZA 4E8BA 1UAMA 1GZ0A 3N4JA 4YQGA 4YVKA 4H3YA 1K3RA 5GMCA 4YQAA 4FMWA 3OINA 3AIAA 4YQDA 1P9PA 1Z85A 2HA8A 4YPYA 4YQ9A 4CNDA 4YPZA 4JALA 2V3KA 3N4KA 4YQ6A 4YQTA 1J85A 4YQOA 1O6DA 1X7OA 4YQ8A 4JWFA 4YQSA 1UAKA 4YVIA 3KW2A 4JWHA 3OIIA 4YQRA 1ZJRA 2EGVA 4YQ7A 2Z0YA 4MCBA 4MCDA 1VHKA 2O3AA 3NK7A 4RG1A 1MXIA 4YQJA 1OY5A 4YQPA 3L8UA 4CNEA 4YQCA 3IC6A 3BBHA 3IEFA 1IPAA 4JWJA 4YQNA 4KGNA 1V6ZA 3NK6A 2EGWA 4YVJA 4YPWA 3KY7A 1VH0A 3QUVA 5D9FA 3AI9X 4X3MA 4YQBA 4KDZA 3GYQA 4YQ0A 4YQKA 4YVHA 1TO0A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1VHY A;  4L69 A;  4YQ5 A;  1NS5 A;  1UAJ A;  1V2X A;  4FAK A;  3KNU A;  2CX8 A;  2QMM A;  3OIJ A;  3BBE A;  4MCC A;  5FAI A;  3ILK A;  2QWV A;  3E5Y A;  4YQ2 A;  2V3J A;  3O7B A;  4JAK A;  5CO4 A;  1NXZ A;  4YQQ A;  4YVG A;  3ONP A;  4J3C A;  3AXZ A;  2YY8 A;  1UAL A;  4PZK A;  4YQI A;  4YPX A;  4CNG A;  3BBD A;  4YQ1 A;  1X7P A;  2I6D A;  4YQ3 A;  3KTY A;  4YQ4 A;  4XBO A;  4IG6 A;  5GM8 A;  3DCM X;  4YQL A;  4X3L A;  4CNF A;  5GMB A;  4H3Z A;  4E8B A;  1UAM A;  1GZ0 A;  3N4J A;  4YQG A;  4YVK A;  4H3Y A;  1K3R A;  5GMC A;  4YQA A;  3OIN A;  3AIA A;  4YQD A;  1P9P A;  1Z85 A;  2HA8 A;  4YPY A;  4YQ9 A;  4CND A;  4YPZ A;  4JAL A;  2V3K A;  3N4K A;  4YQ6 A;  4YQT A;  1J85 A;  4YQO A;  1O6D A;  1X7O A;  4YQ8 A;  4YQS A;  1UAK A;  4YVI A;  3KW2 A;  3OII A;  4YQR A;  1ZJR A;  2EGV A;  4YQ7 A;  2Z0Y A;  4MCB A;  4MCD A;  1VHK A;  2O3A A;  3NK7 A;  4RG1 A;  1MXI A;  4YQJ A;  1OY5 A;  4YQP A;  3L8U A;  4CNE A;  4YQC A;  3IC6 A;  3BBH A;  3IEF A;  1IPA A;  4YQN A;  4KGN A;  1V6Z A;  3NK6 A;  2EGW A;  4YVJ A;  4YPW A;  3KY7 A;  1VH0 A;  3QUV A;  5D9F A;  3AI9 X;  4X3M A;  4YQB A;  4KDZ A;  3GYQ A;  4YQ0 A;  4YQK A;  4YVH A;  1TO0 A; 
#chains in the Genus database with same CATH topology
 1VHY A;  4L69 A;  4YQ5 A;  1NS5 A;  1UAJ A;  1V2X A;  4FAK A;  3KNU A;  2CX8 A;  2QMM A;  3OIJ A;  3BBE A;  4MCC A;  5FAI A;  3ILK A;  2QWV A;  3E5Y A;  4YQ2 A;  2V3J A;  3O7B A;  4JAK A;  5CO4 A;  1NXZ A;  4YQQ A;  4YVG A;  3ONP A;  4J3C A;  3AXZ A;  2YY8 A;  1UAL A;  4PZK A;  4YQI A;  4JWG A;  4YPX A;  4CNG A;  3BBD A;  4YQ1 A;  1X7P A;  2I6D A;  4YQ3 A;  3KTY A;  4YQ4 A;  4XBO A;  4IG6 A;  5GM8 A;  3DCM X;  4YQL A;  4X3L A;  4CNF A;  5GMB A;  4H3Z A;  4E8B A;  1UAM A;  1GZ0 A;  3N4J A;  4YQG A;  4YVK A;  4H3Y A;  1K3R A;  5GMC A;  4YQA A;  4FMW A;  3OIN A;  3AIA A;  4YQD A;  1P9P A;  1Z85 A;  2HA8 A;  4YPY A;  4YQ9 A;  4CND A;  4YPZ A;  4JAL A;  2V3K A;  3N4K A;  4YQ6 A;  4YQT A;  1J85 A;  4YQO A;  1O6D A;  1X7O A;  4YQ8 A;  4JWF A;  4YQS A;  1UAK A;  4YVI A;  3KW2 A;  4JWH A;  3OII A;  4YQR A;  1ZJR A;  2EGV A;  4YQ7 A;  2Z0Y A;  4MCB A;  4MCD A;  1VHK A;  2O3A A;  3NK7 A;  4RG1 A;  1MXI A;  4YQJ A;  1OY5 A;  4YQP A;  3L8U A;  4CNE A;  4YQC A;  3IC6 A;  3BBH A;  3IEF A;  1IPA A;  4JWJ A;  4YQN A;  4KGN A;  1V6Z A;  3NK6 A;  2EGW A;  4YVJ A;  4YPW A;  3KY7 A;  1VH0 A;  3QUV A;  5D9F A;  3AI9 X;  4X3M A;  4YQB A;  4KDZ A;  3GYQ A;  4YQ0 A;  4YQK A;  4YVH A;  1TO0 A; 
#chains in the Genus database with same CATH homology
 1VHY A;  4L69 A;  4YQ5 A;  1NS5 A;  1UAJ A;  1V2X A;  4FAK A;  3KNU A;  2CX8 A;  2QMM A;  3OIJ A;  3BBE A;  4MCC A;  5FAI A;  3ILK A;  2QWV A;  3E5Y A;  4YQ2 A;  2V3J A;  3O7B A;  4JAK A;  5CO4 A;  1NXZ A;  4YQQ A;  4YVG A;  3ONP A;  4J3C A;  3AXZ A;  2YY8 A;  1UAL A;  4PZK A;  4YQI A;  4JWG A;  4YPX A;  4CNG A;  3BBD A;  4YQ1 A;  1X7P A;  2I6D A;  4YQ3 A;  3KTY A;  4YQ4 A;  4XBO A;  4IG6 A;  5GM8 A;  3DCM X;  4YQL A;  4X3L A;  4CNF A;  5GMB A;  4H3Z A;  4E8B A;  1UAM A;  1GZ0 A;  3N4J A;  4YQG A;  4YVK A;  4H3Y A;  1K3R A;  5GMC A;  4YQA A;  4FMW A;  3OIN A;  3AIA A;  4YQD A;  1P9P A;  1Z85 A;  2HA8 A;  4YPY A;  4YQ9 A;  4CND A;  4YPZ A;  4JAL A;  2V3K A;  3N4K A;  4YQ6 A;  4YQT A;  1J85 A;  4YQO A;  1O6D A;  1X7O A;  4YQ8 A;  4JWF A;  4YQS A;  1UAK A;  4YVI A;  3KW2 A;  4JWH A;  3OII A;  4YQR A;  1ZJR A;  2EGV A;  4YQ7 A;  2Z0Y A;  4MCB A;  4MCD A;  1VHK A;  2O3A A;  3NK7 A;  4RG1 A;  1MXI A;  4YQJ A;  1OY5 A;  4YQP A;  3L8U A;  4CNE A;  4YQC A;  3IC6 A;  3BBH A;  3IEF A;  1IPA A;  4JWJ A;  4YQN A;  4KGN A;  1V6Z A;  3NK6 A;  2EGW A;  4YVJ A;  4YPW A;  3KY7 A;  1VH0 A;  3QUV A;  5D9F A;  3AI9 X;  4X3M A;  4YQB A;  4KDZ A;  3GYQ A;  4YQ0 A;  4YQK A;  4YVH A;  1TO0 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4CNFA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations