4CNGA

Crystal structure of sulfolobus acidocaldarius trmj in complex with s-adenosyl-l-homocysteine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
Knots found
sequence length
156
structure length
156
Chain Sequence
MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKGSEVIEKMMKITNNFDDAIRDVDLKIATSSIADIKGDLLRKSIRPIDLERLIKDKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus acidocaldarius
molecule keywords SPOU RRNA METHYLASE
total genus 51
structure length 156
sequence length 156
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cngA00
2Z0YA 1UAJA 4KDZA 1J85A 4YQ1A 4YQOA 4CNEA 4YQ4A 4H3YA 1GZ0A 3OIJA 3KTYA 4YQSA 4YQGA 4YQKA 4YQLA 2QMMA 4YVJA 4YVGA 2O3AA 4YQ2A 4YQCA 1V2XA 3GYQA 4YQAA 1X7PA 2YY8A 1TO0A 3L8UA 1P9PA 4YQPA 5GM8A 4X3MA 4XBOA 3BBEA 2QWVA 2EGWA 4KGNA 3BBHA 1ZJRA 3ILKA 4YQ9A 4CNFA 2V3JA 1VHKA 5CO4A 1VHYA 3AIAA 3OIIA 3E5YA 5FAIA 5D9FA 4MCDA 4MCBA 3ONPA 4YQIA 3QUVA 1K3RA 3N4JA 1MXIA 1OY5A 4YQBA 4CNDA 2CX8A 3KY7A 4J3CA 4YQ0A 1V6ZA 1VH0A 3DCMX 3IC6A 4YQDA 4YQ7A 4YQ6A 2HA8A 4YQ8A 4YPZA 1X7OA 4YQRA 4X3LA 1UAKA 4YQJA 3BBDA 4RG1A 1Z85A 3AXZA 3IEFA 4CNGA 4YQNA 4YVKA 4YQQA 1NXZA 3OINA 4YVHA 1NS5A 3AI9X 4JAKA 4YQ3A 3NK6A 4YPXA 4FAKA 4YPYA 3KW2A 4E8BA 4YPWA 1IPAA 4YQTA 1UAMA 4JALA 1UALA 3KNUA 2EGVA 4L69A 5GMCA 4YQ5A 4YVIA 4H3ZA 3N4KA 1O6DA 4MCCA 2I6DA 4IG6A 4PZKA 3NK7A 3O7BA 5GMBA 2V3KA
chains in the Genus database with same CATH superfamily
2Z0YA 1UAJA 4JWGA 4KDZA 1J85A 4YQ1A 4YQOA 4CNEA 4YQ4A 4H3YA 1GZ0A 3OIJA 3KTYA 4JWHA 4YQSA 4YQGA 4YQKA 4YQLA 2QMMA 4YVJA 4YVGA 2O3AA 4YQ2A 4YQCA 1V2XA 3GYQA 4YQAA 1X7PA 2YY8A 1TO0A 3L8UA 1P9PA 4YQPA 5GM8A 4JWJA 4X3MA 3BBEA 4XBOA 2QWVA 2EGWA 4KGNA 3BBHA 1ZJRA 3ILKA 4YQ9A 4CNFA 2V3JA 1VHKA 5CO4A 1VHYA 3AIAA 3OIIA 3E5YA 5FAIA 5D9FA 4MCDA 4MCBA 3ONPA 4YQIA 3QUVA 1K3RA 3N4JA 1MXIA 1OY5A 4YQBA 4CNDA 2CX8A 3KY7A 4J3CA 4YQ0A 1V6ZA 1VH0A 3DCMX 3IC6A 4YQDA 4YQ7A 4YQ6A 2HA8A 4YQ8A 4YPZA 1X7OA 4YQRA 4X3LA 1UAKA 4YQJA 3BBDA 4RG1A 1Z85A 3AXZA 3IEFA 4CNGA 4YQNA 4YVKA 4YQQA 4JWFA 4FMWA 1NXZA 3OINA 4YVHA 1NS5A 3AI9X 4JAKA 4YQ3A 3NK6A 4YPXA 4FAKA 4YPYA 3KW2A 4E8BA 4YPWA 1IPAA 4YQTA 1UAMA 4JALA 1UALA 3KNUA 2EGVA 4L69A 5GMCA 4YQ5A 4YVIA 4H3ZA 3N4KA 1O6DA 4MCCA 2I6DA 4IG6A 4PZKA 3NK7A 3O7BA 5GMBA 2V3KA
chains in the Genus database with same CATH topology
2Z0YA 1UAJA 4JWGA 4KDZA 1J85A 4YQ1A 4YQOA 4CNEA 4YQ4A 4H3YA 1GZ0A 3OIJA 3KTYA 4JWHA 4YQSA 4YQGA 4YQKA 4YQLA 2QMMA 4YVJA 4YVGA 2O3AA 4YQ2A 4YQCA 1V2XA 3GYQA 4YQAA 1X7PA 2YY8A 1TO0A 3L8UA 1P9PA 4YQPA 5GM8A 4JWJA 4X3MA 3BBEA 4XBOA 2QWVA 2EGWA 4KGNA 3BBHA 1ZJRA 3ILKA 4YQ9A 4CNFA 2V3JA 1VHKA 5CO4A 1VHYA 3AIAA 3OIIA 3E5YA 5FAIA 5D9FA 4MCDA 4MCBA 3ONPA 4YQIA 3QUVA 1K3RA 3N4JA 1MXIA 1OY5A 4YQBA 4CNDA 2CX8A 3KY7A 4J3CA 4YQ0A 1V6ZA 1VH0A 3DCMX 3IC6A 4YQDA 4YQ7A 4YQ6A 2HA8A 4YQ8A 4YPZA 1X7OA 4YQRA 4X3LA 1UAKA 4YQJA 3BBDA 4RG1A 1Z85A 3AXZA 3IEFA 4CNGA 4YQNA 4YVKA 4YQQA 4JWFA 4FMWA 1NXZA 3OINA 4YVHA 1NS5A 3AI9X 4JAKA 4YQ3A 3NK6A 4YPXA 4FAKA 4YPYA 3KW2A 4E8BA 4YPWA 1IPAA 4YQTA 1UAMA 4JALA 1UALA 3KNUA 2EGVA 4L69A 5GMCA 4YQ5A 4YVIA 4H3ZA 3N4KA 1O6DA 4MCCA 2I6DA 4IG6A 4PZKA 3NK7A 3O7BA 5GMBA 2V3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z0Y A;  1UAJ A;  4KDZ A;  1J85 A;  4YQ1 A;  4YQO A;  4CNE A;  4YQ4 A;  4H3Y A;  1GZ0 A;  3OIJ A;  3KTY A;  4YQS A;  4YQG A;  4YQK A;  4YQL A;  2QMM A;  4YVJ A;  4YVG A;  2O3A A;  4YQ2 A;  4YQC A;  1V2X A;  3GYQ A;  4YQA A;  1X7P A;  2YY8 A;  1TO0 A;  3L8U A;  1P9P A;  4YQP A;  5GM8 A;  4X3M A;  4XBO A;  3BBE A;  2QWV A;  2EGW A;  4KGN A;  3BBH A;  1ZJR A;  3ILK A;  4YQ9 A;  4CNF A;  2V3J A;  1VHK A;  5CO4 A;  1VHY A;  3AIA A;  3OII A;  3E5Y A;  5FAI A;  5D9F A;  4MCD A;  4MCB A;  3ONP A;  4YQI A;  3QUV A;  1K3R A;  3N4J A;  1MXI A;  1OY5 A;  4YQB A;  4CND A;  2CX8 A;  3KY7 A;  4J3C A;  4YQ0 A;  1V6Z A;  1VH0 A;  3DCM X;  3IC6 A;  4YQD A;  4YQ7 A;  4YQ6 A;  2HA8 A;  4YQ8 A;  4YPZ A;  1X7O A;  4YQR A;  4X3L A;  1UAK A;  4YQJ A;  3BBD A;  4RG1 A;  1Z85 A;  3AXZ A;  3IEF A;  4CNG A;  4YQN A;  4YVK A;  4YQQ A;  1NXZ A;  3OIN A;  4YVH A;  1NS5 A;  3AI9 X;  4JAK A;  4YQ3 A;  3NK6 A;  4YPX A;  4FAK A;  4YPY A;  3KW2 A;  4E8B A;  4YPW A;  1IPA A;  4YQT A;  1UAM A;  4JAL A;  1UAL A;  3KNU A;  2EGV A;  4L69 A;  5GMC A;  4YQ5 A;  4YVI A;  4H3Z A;  3N4K A;  1O6D A;  4MCC A;  2I6D A;  4IG6 A;  4PZK A;  3NK7 A;  3O7B A;  5GMB A;  2V3K A; 
#chains in the Genus database with same CATH topology
 2Z0Y A;  1UAJ A;  4JWG A;  4KDZ A;  1J85 A;  4YQ1 A;  4YQO A;  4CNE A;  4YQ4 A;  4H3Y A;  1GZ0 A;  3OIJ A;  3KTY A;  4JWH A;  4YQS A;  4YQG A;  4YQK A;  4YQL A;  2QMM A;  4YVJ A;  4YVG A;  2O3A A;  4YQ2 A;  4YQC A;  1V2X A;  3GYQ A;  4YQA A;  1X7P A;  2YY8 A;  1TO0 A;  3L8U A;  1P9P A;  4YQP A;  5GM8 A;  4JWJ A;  4X3M A;  3BBE A;  4XBO A;  2QWV A;  2EGW A;  4KGN A;  3BBH A;  1ZJR A;  3ILK A;  4YQ9 A;  4CNF A;  2V3J A;  1VHK A;  5CO4 A;  1VHY A;  3AIA A;  3OII A;  3E5Y A;  5FAI A;  5D9F A;  4MCD A;  4MCB A;  3ONP A;  4YQI A;  3QUV A;  1K3R A;  3N4J A;  1MXI A;  1OY5 A;  4YQB A;  4CND A;  2CX8 A;  3KY7 A;  4J3C A;  4YQ0 A;  1V6Z A;  1VH0 A;  3DCM X;  3IC6 A;  4YQD A;  4YQ7 A;  4YQ6 A;  2HA8 A;  4YQ8 A;  4YPZ A;  1X7O A;  4YQR A;  4X3L A;  1UAK A;  4YQJ A;  3BBD A;  4RG1 A;  1Z85 A;  3AXZ A;  3IEF A;  4CNG A;  4YQN A;  4YVK A;  4YQQ A;  4JWF A;  4FMW A;  1NXZ A;  3OIN A;  4YVH A;  1NS5 A;  3AI9 X;  4JAK A;  4YQ3 A;  3NK6 A;  4YPX A;  4FAK A;  4YPY A;  3KW2 A;  4E8B A;  4YPW A;  1IPA A;  4YQT A;  1UAM A;  4JAL A;  1UAL A;  3KNU A;  2EGV A;  4L69 A;  5GMC A;  4YQ5 A;  4YVI A;  4H3Z A;  3N4K A;  1O6D A;  4MCC A;  2I6D A;  4IG6 A;  4PZK A;  3NK7 A;  3O7B A;  5GMB A;  2V3K A; 
#chains in the Genus database with same CATH homology
 2Z0Y A;  1UAJ A;  4JWG A;  4KDZ A;  1J85 A;  4YQ1 A;  4YQO A;  4CNE A;  4YQ4 A;  4H3Y A;  1GZ0 A;  3OIJ A;  3KTY A;  4JWH A;  4YQS A;  4YQG A;  4YQK A;  4YQL A;  2QMM A;  4YVJ A;  4YVG A;  2O3A A;  4YQ2 A;  4YQC A;  1V2X A;  3GYQ A;  4YQA A;  1X7P A;  2YY8 A;  1TO0 A;  3L8U A;  1P9P A;  4YQP A;  5GM8 A;  4JWJ A;  4X3M A;  3BBE A;  4XBO A;  2QWV A;  2EGW A;  4KGN A;  3BBH A;  1ZJR A;  3ILK A;  4YQ9 A;  4CNF A;  2V3J A;  1VHK A;  5CO4 A;  1VHY A;  3AIA A;  3OII A;  3E5Y A;  5FAI A;  5D9F A;  4MCD A;  4MCB A;  3ONP A;  4YQI A;  3QUV A;  1K3R A;  3N4J A;  1MXI A;  1OY5 A;  4YQB A;  4CND A;  2CX8 A;  3KY7 A;  4J3C A;  4YQ0 A;  1V6Z A;  1VH0 A;  3DCM X;  3IC6 A;  4YQD A;  4YQ7 A;  4YQ6 A;  2HA8 A;  4YQ8 A;  4YPZ A;  1X7O A;  4YQR A;  4X3L A;  1UAK A;  4YQJ A;  3BBD A;  4RG1 A;  1Z85 A;  3AXZ A;  3IEF A;  4CNG A;  4YQN A;  4YVK A;  4YQQ A;  4JWF A;  4FMW A;  1NXZ A;  3OIN A;  4YVH A;  1NS5 A;  3AI9 X;  4JAK A;  4YQ3 A;  3NK6 A;  4YPX A;  4FAK A;  4YPY A;  3KW2 A;  4E8B A;  4YPW A;  1IPA A;  4YQT A;  1UAM A;  4JAL A;  1UAL A;  3KNU A;  2EGV A;  4L69 A;  5GMC A;  4YQ5 A;  4YVI A;  4H3Z A;  3N4K A;  1O6D A;  4MCC A;  2I6D A;  4IG6 A;  4PZK A;  3NK7 A;  3O7B A;  5GMB A;  2V3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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