4CNGA

Crystal structure of sulfolobus acidocaldarius trmj in complex with s-adenosyl-l-homocysteine
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
Knots found
sequence length
156
structure length
156
Chain Sequence
MTIRLVIVEPEGAYNLGFIARLVKNFLIDEFYVVNPKADINEAIKFSAKGSEVIEKMMKITNNFDDAIRDVDLKIATSSIADIKGDLLRKSIRPIDLERLIKDKKVAFIFGRESVGLTREEIAKSDFLLFIPANPEYPVLNLSHAVGIVLYELWRN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of Two Homologous 2'-O-Methyltransferases Showing Different Specificities for Their tRNA Substrates.
pubmed doi rcsb
molecule tags Transferase
source organism Sulfolobus acidocaldarius
molecule keywords SPOU RRNA METHYLASE
total genus 51
structure length 156
sequence length 156
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.200: tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00588 SpoU_methylase SpoU rRNA Methylase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4cngA00
3KNUA 1OY5A 4YQLA 3ILKA 4YQJA 1IPAA 4YQTA 3AXZA 4JAKA 2Z0YA 4YVIA 3OIJA 4YVJA 1MXIA 2QWVA 4L69A 1UAJA 2O3AA 4KGNA 4YQNA 4YQRA 1ZJRA 5FAIA 1UAKA 4YQ5A 2CX8A 5GMBA 4YQBA 4YQAA 4YQ2A 3NK7A 4YPXA 1VH0A 2V3KA 3E5YA 4CNFA 4X3MA 4YQ9A 4YQCA 4YQGA 5D9FA 1Z85A 4YPZA 3IC6A 4YQ7A 1J85A 5CO4A 1UAMA 1GZ0A 2EGWA 1TO0A 1NXZA 2I6DA 4H3YA 1O6DA 4YQ0A 4YVKA 1V2XA 5GMCA 3AIAA 3N4JA 3ONPA 4CNEA 3BBEA 1K3RA 2V3JA 4JALA 5GM8A 3L8UA 2HA8A 3KY7A 4YQSA 4YQIA 4IG6A 1X7OA 3AI9X 3DCMX 2EGVA 3BBDA 4YQPA 4RG1A 4J3CA 1X7PA 1NS5A 4MCBA 4CNGA 4YQ3A 1V6ZA 4YQDA 4FAKA 4YQ6A 2QMMA 3O7BA 4YPYA 4KDZA 3N4KA 4YQ4A 4YQKA 4YPWA 4H3ZA 4XBOA 3OINA 3KTYA 4MCDA 4YQ1A 3IEFA 3NK6A 4YQQA 3GYQA 4YQ8A 1P9PA 1VHYA 3OIIA 4X3LA 3KW2A 4YQOA 3BBHA 3QUVA 4PZKA 4YVGA 4E8BA 2YY8A 4YVHA 1VHKA 4CNDA 1UALA 4MCCA
chains in the Genus database with same CATH superfamily
3KNUA 1OY5A 4YQLA 3ILKA 4YQJA 1IPAA 4YQTA 3AXZA 4JAKA 2Z0YA 4YVIA 3OIJA 4YVJA 1MXIA 2QWVA 4L69A 1UAJA 2O3AA 4KGNA 4YQNA 4YQRA 1ZJRA 4JWFA 5FAIA 1UAKA 4YQ5A 2CX8A 5GMBA 4YQBA 4YQAA 4YQ2A 3NK7A 4YPXA 1VH0A 4JWHA 2V3KA 3E5YA 4CNFA 4X3MA 4YQ9A 4YQCA 4YQGA 5D9FA 1Z85A 4YPZA 3IC6A 4YQ7A 1J85A 5CO4A 1UAMA 1GZ0A 2EGWA 1TO0A 1NXZA 2I6DA 4H3YA 1O6DA 4YQ0A 4YVKA 1V2XA 5GMCA 3AIAA 3N4JA 3ONPA 4CNEA 3BBEA 1K3RA 2V3JA 4JALA 5GM8A 3L8UA 2HA8A 3KY7A 4YQSA 4YQIA 4IG6A 4JWJA 1X7OA 3AI9X 3DCMX 4JWGA 2EGVA 3BBDA 4YQPA 4RG1A 4J3CA 1X7PA 1NS5A 4MCBA 4CNGA 4YQ3A 1V6ZA 4YQDA 4FAKA 4YQ6A 2QMMA 3O7BA 4YPYA 4KDZA 3N4KA 4YQ4A 4YQKA 4YPWA 4H3ZA 4XBOA 3OINA 3KTYA 4MCDA 4YQ1A 3IEFA 3NK6A 4YQQA 3GYQA 4YQ8A 1P9PA 4MCCA 1VHYA 3OIIA 4X3LA 3KW2A 4YQOA 3BBHA 3QUVA 4PZKA 4YVGA 4E8BA 2YY8A 4YVHA 1VHKA 4CNDA 1UALA 4FMWA
chains in the Genus database with same CATH topology
3KNUA 1OY5A 4YQLA 3ILKA 4YQJA 1IPAA 4YQTA 3AXZA 4JAKA 2Z0YA 4YVIA 3OIJA 4YVJA 1MXIA 2QWVA 4L69A 1UAJA 2O3AA 4KGNA 4YQNA 4YQRA 1ZJRA 4JWFA 5FAIA 1UAKA 4YQ5A 2CX8A 5GMBA 4YQBA 4YQAA 4YQ2A 3NK7A 4YPXA 1VH0A 4JWHA 2V3KA 3E5YA 4CNFA 4X3MA 4YQ9A 4YQCA 4YQGA 5D9FA 1Z85A 4YPZA 3IC6A 4YQ7A 1J85A 5CO4A 1UAMA 1GZ0A 2EGWA 1TO0A 1NXZA 2I6DA 4H3YA 1O6DA 4YQ0A 4YVKA 1V2XA 5GMCA 3AIAA 3N4JA 3ONPA 4CNEA 3BBEA 1K3RA 2V3JA 4JALA 5GM8A 3L8UA 2HA8A 3KY7A 4YQSA 4YQIA 4IG6A 4JWJA 1X7OA 3AI9X 3DCMX 4JWGA 2EGVA 3BBDA 4YQPA 4RG1A 4J3CA 1X7PA 1NS5A 4MCBA 4CNGA 4YQ3A 1V6ZA 4YQDA 4FAKA 4YQ6A 2QMMA 3O7BA 4YPYA 4KDZA 3N4KA 4YQ4A 4YQKA 4YPWA 4H3ZA 4XBOA 3OINA 3KTYA 4MCDA 4YQ1A 3IEFA 3NK6A 4YQQA 3GYQA 4YQ8A 1P9PA 4MCCA 1VHYA 3OIIA 4X3LA 3KW2A 4YQOA 3BBHA 3QUVA 4PZKA 4YVGA 4E8BA 2YY8A 4YVHA 1VHKA 4CNDA 1UALA 4FMWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KNU A;  1OY5 A;  4YQL A;  3ILK A;  4YQJ A;  1IPA A;  4YQT A;  3AXZ A;  4JAK A;  2Z0Y A;  4YVI A;  3OIJ A;  4YVJ A;  1MXI A;  2QWV A;  4L69 A;  1UAJ A;  2O3A A;  4KGN A;  4YQN A;  4YQR A;  1ZJR A;  5FAI A;  1UAK A;  4YQ5 A;  2CX8 A;  5GMB A;  4YQB A;  4YQA A;  4YQ2 A;  3NK7 A;  4YPX A;  1VH0 A;  2V3K A;  3E5Y A;  4CNF A;  4X3M A;  4YQ9 A;  4YQC A;  4YQG A;  5D9F A;  1Z85 A;  4YPZ A;  3IC6 A;  4YQ7 A;  1J85 A;  5CO4 A;  1UAM A;  1GZ0 A;  2EGW A;  1TO0 A;  1NXZ A;  2I6D A;  4H3Y A;  1O6D A;  4YQ0 A;  4YVK A;  1V2X A;  5GMC A;  3AIA A;  3N4J A;  3ONP A;  4CNE A;  3BBE A;  1K3R A;  2V3J A;  4JAL A;  5GM8 A;  3L8U A;  2HA8 A;  3KY7 A;  4YQS A;  4YQI A;  4IG6 A;  1X7O A;  3AI9 X;  3DCM X;  2EGV A;  3BBD A;  4YQP A;  4RG1 A;  4J3C A;  1X7P A;  1NS5 A;  4MCB A;  4CNG A;  4YQ3 A;  1V6Z A;  4YQD A;  4FAK A;  4YQ6 A;  2QMM A;  3O7B A;  4YPY A;  4KDZ A;  3N4K A;  4YQ4 A;  4YQK A;  4YPW A;  4H3Z A;  4XBO A;  3OIN A;  3KTY A;  4MCD A;  4YQ1 A;  3IEF A;  3NK6 A;  4YQQ A;  3GYQ A;  4YQ8 A;  1P9P A;  1VHY A;  3OII A;  4X3L A;  3KW2 A;  4YQO A;  3BBH A;  3QUV A;  4PZK A;  4YVG A;  4E8B A;  2YY8 A;  4YVH A;  1VHK A;  4CND A;  1UAL A;  4MCC A; 
#chains in the Genus database with same CATH topology
 3KNU A;  1OY5 A;  4YQL A;  3ILK A;  4YQJ A;  1IPA A;  4YQT A;  3AXZ A;  4JAK A;  2Z0Y A;  4YVI A;  3OIJ A;  4YVJ A;  1MXI A;  2QWV A;  4L69 A;  1UAJ A;  2O3A A;  4KGN A;  4YQN A;  4YQR A;  1ZJR A;  4JWF A;  5FAI A;  1UAK A;  4YQ5 A;  2CX8 A;  5GMB A;  4YQB A;  4YQA A;  4YQ2 A;  3NK7 A;  4YPX A;  1VH0 A;  4JWH A;  2V3K A;  3E5Y A;  4CNF A;  4X3M A;  4YQ9 A;  4YQC A;  4YQG A;  5D9F A;  1Z85 A;  4YPZ A;  3IC6 A;  4YQ7 A;  1J85 A;  5CO4 A;  1UAM A;  1GZ0 A;  2EGW A;  1TO0 A;  1NXZ A;  2I6D A;  4H3Y A;  1O6D A;  4YQ0 A;  4YVK A;  1V2X A;  5GMC A;  3AIA A;  3N4J A;  3ONP A;  4CNE A;  3BBE A;  1K3R A;  2V3J A;  4JAL A;  5GM8 A;  3L8U A;  2HA8 A;  3KY7 A;  4YQS A;  4YQI A;  4IG6 A;  4JWJ A;  1X7O A;  3AI9 X;  3DCM X;  4JWG A;  2EGV A;  3BBD A;  4YQP A;  4RG1 A;  4J3C A;  1X7P A;  1NS5 A;  4MCB A;  4CNG A;  4YQ3 A;  1V6Z A;  4YQD A;  4FAK A;  4YQ6 A;  2QMM A;  3O7B A;  4YPY A;  4KDZ A;  3N4K A;  4YQ4 A;  4YQK A;  4YPW A;  4H3Z A;  4XBO A;  3OIN A;  3KTY A;  4MCD A;  4YQ1 A;  3IEF A;  3NK6 A;  4YQQ A;  3GYQ A;  4YQ8 A;  1P9P A;  4MCC A;  1VHY A;  3OII A;  4X3L A;  3KW2 A;  4YQO A;  3BBH A;  3QUV A;  4PZK A;  4YVG A;  4E8B A;  2YY8 A;  4YVH A;  1VHK A;  4CND A;  1UAL A;  4FMW A; 
#chains in the Genus database with same CATH homology
 3KNU A;  1OY5 A;  4YQL A;  3ILK A;  4YQJ A;  1IPA A;  4YQT A;  3AXZ A;  4JAK A;  2Z0Y A;  4YVI A;  3OIJ A;  4YVJ A;  1MXI A;  2QWV A;  4L69 A;  1UAJ A;  2O3A A;  4KGN A;  4YQN A;  4YQR A;  1ZJR A;  4JWF A;  5FAI A;  1UAK A;  4YQ5 A;  2CX8 A;  5GMB A;  4YQB A;  4YQA A;  4YQ2 A;  3NK7 A;  4YPX A;  1VH0 A;  4JWH A;  2V3K A;  3E5Y A;  4CNF A;  4X3M A;  4YQ9 A;  4YQC A;  4YQG A;  5D9F A;  1Z85 A;  4YPZ A;  3IC6 A;  4YQ7 A;  1J85 A;  5CO4 A;  1UAM A;  1GZ0 A;  2EGW A;  1TO0 A;  1NXZ A;  2I6D A;  4H3Y A;  1O6D A;  4YQ0 A;  4YVK A;  1V2X A;  5GMC A;  3AIA A;  3N4J A;  3ONP A;  4CNE A;  3BBE A;  1K3R A;  2V3J A;  4JAL A;  5GM8 A;  3L8U A;  2HA8 A;  3KY7 A;  4YQS A;  4YQI A;  4IG6 A;  4JWJ A;  1X7O A;  3AI9 X;  3DCM X;  4JWG A;  2EGV A;  3BBD A;  4YQP A;  4RG1 A;  4J3C A;  1X7P A;  1NS5 A;  4MCB A;  4CNG A;  4YQ3 A;  1V6Z A;  4YQD A;  4FAK A;  4YQ6 A;  2QMM A;  3O7B A;  4YPY A;  4KDZ A;  3N4K A;  4YQ4 A;  4YQK A;  4YPW A;  4H3Z A;  4XBO A;  3OIN A;  3KTY A;  4MCD A;  4YQ1 A;  3IEF A;  3NK6 A;  4YQQ A;  3GYQ A;  4YQ8 A;  1P9P A;  4MCC A;  1VHY A;  3OII A;  4X3L A;  3KW2 A;  4YQO A;  3BBH A;  3QUV A;  4PZK A;  4YVG A;  4E8B A;  2YY8 A;  4YVH A;  1VHK A;  4CND A;  1UAL A;  4FMW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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