4FAKA

Crystal structure of orfx in complex with s-adenosylmethionine
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
Knots found
sequence length
163
structure length
163
Chain Sequence
AAEFMKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site.
pubmed doi rcsb
molecule tags Transferase, ribosomal protein
source organism Staphylococcus aureus
molecule keywords Ribosomal RNA large subunit methyltransferase H
total genus 53
structure length 163
sequence length 163
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.177: 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase.
pdb deposition date 2012-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02590 SPOUT_MTase Predicted SPOUT methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4fakA00
2CX8A 4MCCA 1MXIA 3N4KA 1V6ZA 1ZJRA 4CNGA 3IC6A 4CNEA 5GM8A 3NK7A 4KGNA 1NXZA 5CO4A 3L8UA 2QWVA 4XBOA 4YVJA 1P9PA 4YQ1A 4CNFA 4MCBA 1GZ0A 1VH0A 4RG1A 1UALA 1UAKA 4IG6A 1OY5A 4YPZA 4YQIA 3E5YA 4X3MA 4YVKA 2HA8A 3OIJA 4YQDA 4YQOA 4YQ5A 4YQSA 2V3JA 4YPYA 3OIIA 4YPWA 4H3YA 3GYQA 4YVGA 2YY8A 4J3CA 3KTYA 4YQ9A 3KNUA 4YQJA 4L69A 1IPAA 1UAJA 3QUVA 4YQBA 1VHKA 4YQAA 4YQRA 4YPXA 5GMCA 2I6DA 4YQ7A 1K3RA 2Z0YA 4YQNA 4YVHA 4YQPA 5GMBA 1NS5A 4CNDA 4E8BA 4YQCA 4PZKA 4JAKA 4YQ4A 3O7BA 3AXZA 3ONPA 2EGWA 1Z85A 4YQKA 2EGVA 3BBHA 3AIAA 4JALA 4X3LA 3BBDA 4FAKA 2QMMA 1VHYA 4H3ZA 3KW2A 1TO0A 4MCDA 3AI9X 4YQLA 5D9FA 3KY7A 3N4JA 3BBEA 4YVIA 4YQ6A 4YQ8A 1O6DA 3DCMX 3IEFA 1X7OA 4YQTA 1V2XA 4KDZA 2V3KA 3ILKA 3OINA 4YQ0A 1UAMA 5FAIA 4YQ2A 1J85A 4YQGA 4YQQA 1X7PA 4YQ3A 3NK6A 2O3AA
chains in the Genus database with same CATH superfamily
2CX8A 4MCCA 1MXIA 3N4KA 1V6ZA 1ZJRA 4CNGA 3IC6A 4CNEA 5GM8A 3NK7A 4KGNA 1NXZA 5CO4A 3L8UA 2QWVA 4XBOA 4YVJA 1P9PA 4YQ1A 4CNFA 4MCBA 1GZ0A 1VH0A 1UALA 4IG6A 1UAKA 4RG1A 1OY5A 4YPZA 4YQIA 3E5YA 4X3MA 4YVKA 2HA8A 3OIJA 4YQDA 4YQOA 4YQ5A 4YQSA 2V3JA 4YPYA 3OIIA 4YPWA 4H3YA 3GYQA 4YVGA 2YY8A 4J3CA 3KTYA 4JWGA 4YQ9A 3KNUA 4YQJA 4L69A 1IPAA 1UAJA 3QUVA 4YQBA 1VHKA 4YQAA 4YQRA 4YPXA 5GMCA 2I6DA 4YQ7A 1K3RA 2Z0YA 4YQNA 4YVHA 4YQPA 5GMBA 1NS5A 4CNDA 4E8BA 4YQCA 4JWFA 4PZKA 4JAKA 4YQ4A 4FMWA 3O7BA 3AXZA 3ONPA 2EGWA 1Z85A 4YQKA 2EGVA 3BBHA 4JWHA 3AIAA 4JALA 4X3LA 3BBDA 4FAKA 2QMMA 1VHYA 4H3ZA 3KW2A 1TO0A 4JWJA 4MCDA 3AI9X 4YQLA 5D9FA 3KY7A 3N4JA 3BBEA 4YVIA 4YQ6A 4YQ8A 1O6DA 3DCMX 3IEFA 1X7OA 4YQTA 1V2XA 4KDZA 2V3KA 3ILKA 3OINA 4YQ0A 1UAMA 5FAIA 4YQ2A 1J85A 4YQGA 4YQQA 1X7PA 4YQ3A 3NK6A 2O3AA
chains in the Genus database with same CATH topology
2CX8A 4MCCA 1MXIA 3N4KA 1V6ZA 1ZJRA 4CNGA 3IC6A 4CNEA 5GM8A 3NK7A 4KGNA 1NXZA 5CO4A 3L8UA 2QWVA 4XBOA 4YVJA 1P9PA 4YQ1A 4CNFA 4MCBA 1GZ0A 1VH0A 1UALA 4IG6A 1UAKA 4RG1A 1OY5A 4YPZA 4YQIA 3E5YA 4X3MA 4YVKA 2HA8A 3OIJA 4YQDA 4YQOA 4YQ5A 4YQSA 2V3JA 4YPYA 3OIIA 4YPWA 4H3YA 3GYQA 4YVGA 2YY8A 4J3CA 3KTYA 4JWGA 4YQ9A 3KNUA 4YQJA 4L69A 1IPAA 1UAJA 3QUVA 4YQBA 1VHKA 4YQAA 4YQRA 4YPXA 5GMCA 2I6DA 4YQ7A 1K3RA 2Z0YA 4YQNA 4YVHA 4YQPA 5GMBA 1NS5A 4CNDA 4E8BA 4YQCA 4JWFA 4PZKA 4JAKA 4YQ4A 4FMWA 3O7BA 3AXZA 3ONPA 2EGWA 1Z85A 4YQKA 2EGVA 3BBHA 4JWHA 3AIAA 4JALA 4X3LA 3BBDA 4FAKA 2QMMA 1VHYA 4H3ZA 3KW2A 1TO0A 4JWJA 4MCDA 3AI9X 4YQLA 5D9FA 3KY7A 3N4JA 3BBEA 4YVIA 4YQ6A 4YQ8A 1O6DA 3DCMX 3IEFA 1X7OA 4YQTA 1V2XA 4KDZA 2V3KA 3ILKA 3OINA 4YQ0A 1UAMA 5FAIA 4YQ2A 1J85A 4YQGA 4YQQA 1X7PA 4YQ3A 3NK6A 2O3AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CX8 A;  4MCC A;  1MXI A;  3N4K A;  1V6Z A;  1ZJR A;  4CNG A;  3IC6 A;  4CNE A;  5GM8 A;  3NK7 A;  4KGN A;  1NXZ A;  5CO4 A;  3L8U A;  2QWV A;  4XBO A;  4YVJ A;  1P9P A;  4YQ1 A;  4CNF A;  4MCB A;  1GZ0 A;  1VH0 A;  4RG1 A;  1UAL A;  1UAK A;  4IG6 A;  1OY5 A;  4YPZ A;  4YQI A;  3E5Y A;  4X3M A;  4YVK A;  2HA8 A;  3OIJ A;  4YQD A;  4YQO A;  4YQ5 A;  4YQS A;  2V3J A;  4YPY A;  3OII A;  4YPW A;  4H3Y A;  3GYQ A;  4YVG A;  2YY8 A;  4J3C A;  3KTY A;  4YQ9 A;  3KNU A;  4YQJ A;  4L69 A;  1IPA A;  1UAJ A;  3QUV A;  4YQB A;  1VHK A;  4YQA A;  4YQR A;  4YPX A;  5GMC A;  2I6D A;  4YQ7 A;  1K3R A;  2Z0Y A;  4YQN A;  4YVH A;  4YQP A;  5GMB A;  1NS5 A;  4CND A;  4E8B A;  4YQC A;  4PZK A;  4JAK A;  4YQ4 A;  3O7B A;  3AXZ A;  3ONP A;  2EGW A;  1Z85 A;  4YQK A;  2EGV A;  3BBH A;  3AIA A;  4JAL A;  4X3L A;  3BBD A;  4FAK A;  2QMM A;  1VHY A;  4H3Z A;  3KW2 A;  1TO0 A;  4MCD A;  3AI9 X;  4YQL A;  5D9F A;  3KY7 A;  3N4J A;  3BBE A;  4YVI A;  4YQ6 A;  4YQ8 A;  1O6D A;  3DCM X;  3IEF A;  1X7O A;  4YQT A;  1V2X A;  4KDZ A;  2V3K A;  3ILK A;  3OIN A;  4YQ0 A;  1UAM A;  5FAI A;  4YQ2 A;  1J85 A;  4YQG A;  4YQQ A;  1X7P A;  4YQ3 A;  3NK6 A;  2O3A A; 
#chains in the Genus database with same CATH topology
 2CX8 A;  4MCC A;  1MXI A;  3N4K A;  1V6Z A;  1ZJR A;  4CNG A;  3IC6 A;  4CNE A;  5GM8 A;  3NK7 A;  4KGN A;  1NXZ A;  5CO4 A;  3L8U A;  2QWV A;  4XBO A;  4YVJ A;  1P9P A;  4YQ1 A;  4CNF A;  4MCB A;  1GZ0 A;  1VH0 A;  1UAL A;  4IG6 A;  1UAK A;  4RG1 A;  1OY5 A;  4YPZ A;  4YQI A;  3E5Y A;  4X3M A;  4YVK A;  2HA8 A;  3OIJ A;  4YQD A;  4YQO A;  4YQ5 A;  4YQS A;  2V3J A;  4YPY A;  3OII A;  4YPW A;  4H3Y A;  3GYQ A;  4YVG A;  2YY8 A;  4J3C A;  3KTY A;  4JWG A;  4YQ9 A;  3KNU A;  4YQJ A;  4L69 A;  1IPA A;  1UAJ A;  3QUV A;  4YQB A;  1VHK A;  4YQA A;  4YQR A;  4YPX A;  5GMC A;  2I6D A;  4YQ7 A;  1K3R A;  2Z0Y A;  4YQN A;  4YVH A;  4YQP A;  5GMB A;  1NS5 A;  4CND A;  4E8B A;  4YQC A;  4JWF A;  4PZK A;  4JAK A;  4YQ4 A;  4FMW A;  3O7B A;  3AXZ A;  3ONP A;  2EGW A;  1Z85 A;  4YQK A;  2EGV A;  3BBH A;  4JWH A;  3AIA A;  4JAL A;  4X3L A;  3BBD A;  4FAK A;  2QMM A;  1VHY A;  4H3Z A;  3KW2 A;  1TO0 A;  4JWJ A;  4MCD A;  3AI9 X;  4YQL A;  5D9F A;  3KY7 A;  3N4J A;  3BBE A;  4YVI A;  4YQ6 A;  4YQ8 A;  1O6D A;  3DCM X;  3IEF A;  1X7O A;  4YQT A;  1V2X A;  4KDZ A;  2V3K A;  3ILK A;  3OIN A;  4YQ0 A;  1UAM A;  5FAI A;  4YQ2 A;  1J85 A;  4YQG A;  4YQQ A;  1X7P A;  4YQ3 A;  3NK6 A;  2O3A A; 
#chains in the Genus database with same CATH homology
 2CX8 A;  4MCC A;  1MXI A;  3N4K A;  1V6Z A;  1ZJR A;  4CNG A;  3IC6 A;  4CNE A;  5GM8 A;  3NK7 A;  4KGN A;  1NXZ A;  5CO4 A;  3L8U A;  2QWV A;  4XBO A;  4YVJ A;  1P9P A;  4YQ1 A;  4CNF A;  4MCB A;  1GZ0 A;  1VH0 A;  1UAL A;  4IG6 A;  1UAK A;  4RG1 A;  1OY5 A;  4YPZ A;  4YQI A;  3E5Y A;  4X3M A;  4YVK A;  2HA8 A;  3OIJ A;  4YQD A;  4YQO A;  4YQ5 A;  4YQS A;  2V3J A;  4YPY A;  3OII A;  4YPW A;  4H3Y A;  3GYQ A;  4YVG A;  2YY8 A;  4J3C A;  3KTY A;  4JWG A;  4YQ9 A;  3KNU A;  4YQJ A;  4L69 A;  1IPA A;  1UAJ A;  3QUV A;  4YQB A;  1VHK A;  4YQA A;  4YQR A;  4YPX A;  5GMC A;  2I6D A;  4YQ7 A;  1K3R A;  2Z0Y A;  4YQN A;  4YVH A;  4YQP A;  5GMB A;  1NS5 A;  4CND A;  4E8B A;  4YQC A;  4JWF A;  4PZK A;  4JAK A;  4YQ4 A;  4FMW A;  3O7B A;  3AXZ A;  3ONP A;  2EGW A;  1Z85 A;  4YQK A;  2EGV A;  3BBH A;  4JWH A;  3AIA A;  4JAL A;  4X3L A;  3BBD A;  4FAK A;  2QMM A;  1VHY A;  4H3Z A;  3KW2 A;  1TO0 A;  4JWJ A;  4MCD A;  3AI9 X;  4YQL A;  5D9F A;  3KY7 A;  3N4J A;  3BBE A;  4YVI A;  4YQ6 A;  4YQ8 A;  1O6D A;  3DCM X;  3IEF A;  1X7O A;  4YQT A;  1V2X A;  4KDZ A;  2V3K A;  3ILK A;  3OIN A;  4YQ0 A;  1UAM A;  5FAI A;  4YQ2 A;  1J85 A;  4YQG A;  4YQQ A;  1X7P A;  4YQ3 A;  3NK6 A;  2O3A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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