4FMW | Genus

Total Genus 58

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	58
Knots found	KnotProt 2.0: K +3₁
sequence length	182
structure length	178
Chain Sequence	RDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVRKVLAVNHVFEIILEYLETRDWQEAFFTILPQR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 178 atoms

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178 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2 rcsb
molecule keywords	RNA (guanine-9-)-methyltransferase domain-containing protein
molecule tags	Transferase
source organism	Homo sapiens
total genus	58
structure length	178
sequence length	182
chains with identical sequence	B
other databases	KnotProt 2.0: K +3₁
ec nomenclature	ec 2.1.1.221: tRNA (guanine(9)-N(1))-methyltransferase.
pdb deposition date	2012-06-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01746	tRNA_m1G_MT	tRNA (Guanine-1)-methyltransferase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.1280.30	Alpha Beta	3-Layer(aba) Sandwich	Alpha/beta knot	Alpha/beta knot	4fmwA00

4JWFA 4JWHA 4JWJA 4JWGA 4FMWA
chains in the Genus database with same CATH superfamily

4YPZA 1NS5A 2V3KA 1OY5A 4JWFA 3O7BA 3OINA 4YQ6A 2EGVA 3N4JA 3QUVA 1K3RA 4YQIA 1VHYA 3KW2A 4YVJA 2CX8A 4L69A 4XBOA 3BBEA 4YPXA 4YPWA 4YQ2A 3BBDA 5D9FA 5GMCA 4CNEA 4H3YA 3E5YA 4X3MA 4JWHA 4KGNA 4YQGA 3N4KA 4YQSA 2V3JA 3ILKA 3KY7A 4YVGA 1O6DA 4J3CA 4JAKA 1IPAA 4YVHA 1X7PA 2O3AA 1TO0A 1J85A 4H3ZA 1V2XA 1UAKA 1X7OA 4YQ9A 4CNFA 4YQJA 1Z85A 1UAJA 2HA8A 4YQRA 4KDZA 4YQQA 4CNGA 1VHKA 4YQ4A 4MCBA 3KNUA 3IC6A 1UAMA 4YQCA 4YQDA 4YVIA 3AIAA 4YQKA 3DCMX 4X3LA 4YQ5A 4YQ7A 4CNDA 3OIJA 4YQ0A 3BBHA 3GYQA 3OIIA 1VH0A 1V6ZA 4IG6A 3L8UA 4YQTA 4E8BA 1UALA 2QWVA 3AI9X 5GMBA 1NXZA 1P9PA 4MCCA 5CO4A 1ZJRA 3NK7A 2Z0YA 4YQLA 4YPYA 3AXZA 4FAKA 3KTYA 3ONPA 4YQOA 4YQNA 4JALA 2YY8A 1GZ0A 4YQ1A 4RG1A 4PZKA 4MCDA 4YQBA 4YQ3A 3IEFA 4YQAA 2I6DA 4JWGA 4YQPA 2EGWA 4YVKA 4YQ8A 3NK6A 4JWJA 1MXIA 5FAIA 2QMMA 5GM8A 4FMWA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4JWF A;  4JWH A;  4JWJ A;  4JWG A;  4FMW A; 
#chains in the Genus database with same CATH topology
 4YPZ A;  1NS5 A;  2V3K A;  1OY5 A;  4JWF A;  3O7B A;  3OIN A;  4YQ6 A;  2EGV A;  3N4J A;  3QUV A;  1K3R A;  4YQI A;  1VHY A;  3KW2 A;  4YVJ A;  2CX8 A;  4L69 A;  4XBO A;  3BBE A;  4YPX A;  4YPW A;  4YQ2 A;  3BBD A;  5D9F A;  5GMC A;  4CNE A;  4H3Y A;  3E5Y A;  4X3M A;  4JWH A;  4KGN A;  4YQG A;  3N4K A;  4YQS A;  2V3J A;  3ILK A;  3KY7 A;  4YVG A;  1O6D A;  4J3C A;  4JAK A;  1IPA A;  4YVH A;  1X7P A;  2O3A A;  1TO0 A;  1J85 A;  4H3Z A;  1V2X A;  1UAK A;  1X7O A;  4YQ9 A;  4CNF A;  4YQJ A;  1Z85 A;  1UAJ A;  2HA8 A;  4YQR A;  4KDZ A;  4YQQ A;  4CNG A;  1VHK A;  4YQ4 A;  4MCB A;  3KNU A;  3IC6 A;  1UAM A;  4YQC A;  4YQD A;  4YVI A;  3AIA A;  4YQK A;  3DCM X;  4X3L A;  4YQ5 A;  4YQ7 A;  4CND A;  3OIJ A;  4YQ0 A;  3BBH A;  3GYQ A;  3OII A;  1VH0 A;  1V6Z A;  4IG6 A;  3L8U A;  4YQT A;  4E8B A;  1UAL A;  2QWV A;  3AI9 X;  5GMB A;  1NXZ A;  1P9P A;  4MCC A;  5CO4 A;  1ZJR A;  3NK7 A;  2Z0Y A;  4YQL A;  4YPY A;  3AXZ A;  4FAK A;  3KTY A;  3ONP A;  4YQO A;  4YQN A;  4JAL A;  2YY8 A;  1GZ0 A;  4YQ1 A;  4RG1 A;  4PZK A;  4MCD A;  4YQB A;  4YQ3 A;  3IEF A;  4YQA A;  2I6D A;  4JWG A;  4YQP A;  2EGW A;  4YVK A;  4YQ8 A;  3NK6 A;  4JWJ A;  1MXI A;  5FAI A;  2QMM A;  5GM8 A;  4FMW A; 
#chains in the Genus database with same CATH homology
 4YPZ A;  1NS5 A;  2V3K A;  1OY5 A;  4JWF A;  3O7B A;  3OIN A;  4YQ6 A;  2EGV A;  3N4J A;  3QUV A;  1K3R A;  4YQI A;  1VHY A;  3KW2 A;  4YVJ A;  2CX8 A;  4L69 A;  4XBO A;  3BBE A;  4YPX A;  4YPW A;  4YQ2 A;  3BBD A;  5D9F A;  5GMC A;  4CNE A;  4H3Y A;  3E5Y A;  4X3M A;  4JWH A;  4KGN A;  4YQG A;  3N4K A;  4YQS A;  2V3J A;  3ILK A;  3KY7 A;  4YVG A;  1O6D A;  4J3C A;  4JAK A;  1IPA A;  4YVH A;  1X7P A;  2O3A A;  1TO0 A;  1J85 A;  4H3Z A;  1V2X A;  1UAK A;  1X7O A;  4YQ9 A;  4CNF A;  4YQJ A;  1Z85 A;  1UAJ A;  2HA8 A;  4YQR A;  4KDZ A;  4YQQ A;  4CNG A;  1VHK A;  4YQ4 A;  4MCB A;  3KNU A;  3IC6 A;  1UAM A;  4YQC A;  4YQD A;  4YVI A;  3AIA A;  4YQK A;  3DCM X;  4X3L A;  4YQ5 A;  4YQ7 A;  4CND A;  3OIJ A;  4YQ0 A;  3BBH A;  3GYQ A;  3OII A;  1VH0 A;  1V6Z A;  4IG6 A;  3L8U A;  4YQT A;  4E8B A;  1UAL A;  2QWV A;  3AI9 X;  5GMB A;  1NXZ A;  1P9P A;  4MCC A;  5CO4 A;  1ZJR A;  3NK7 A;  2Z0Y A;  4YQL A;  4YPY A;  3AXZ A;  4FAK A;  3KTY A;  3ONP A;  4YQO A;  4YQN A;  4JAL A;  2YY8 A;  1GZ0 A;  4YQ1 A;  4RG1 A;  4PZK A;  4MCD A;  4YQB A;  4YQ3 A;  3IEF A;  4YQA A;  2I6D A;  4JWG A;  4YQP A;  2EGW A;  4YVK A;  4YQ8 A;  3NK6 A;  4JWJ A;  1MXI A;  5FAI A;  2QMM A;  5GM8 A;  4FMW A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4FMWA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations