4FMWA

Crystal structure of methyltransferase domain of human rna (guanine-9-) methyltransferase domain containing protein 2
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
Knots found
sequence length
182
structure length
178
Chain Sequence
RDVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLTSHGGQLKKNMDENDKGWVNWKDIHIKPEHYSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVRKVLAVNHVFEIILEYLETRDWQEAFFTILPQR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of methyltransferase domain of human RNA (guanine-9-) methyltransferase domain containing protein 2
rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords RNA (guanine-9-)-methyltransferase domain-containing protein
total genus 58
structure length 178
sequence length 182
chains with identical sequence B
other databases KnotProt 2.0: K +31
ec nomenclature ec 2.1.1.221: tRNA (guanine(9)-N(1))-methyltransferase.
pdb deposition date 2012-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1280.30 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4fmwA00
4FMWA 4JWGA 4JWHA 4JWJA 4JWFA
chains in the Genus database with same CATH superfamily
4JALA 4YPWA 4X3MA 3IEFA 3QUVA 4YQ2A 1VHKA 3OINA 1NXZA 1TO0A 4YQDA 4YQIA 4YQ1A 4YVGA 4YQBA 4YPZA 3BBHA 3N4JA 4YQNA 4YQTA 3ONPA 1GZ0A 4JWJA 4YVHA 2CX8A 3KW2A 4IG6A 4JWFA 5CO4A 4MCDA 4YQPA 2V3JA 1J85A 4YQJA 3AXZA 2I6DA 4YVKA 4KGNA 1OY5A 5GMCA 4YQKA 4YQLA 4CNDA 4FAKA 1X7PA 2V3KA 4YVJA 1NS5A 4YQ3A 4PZKA 4CNFA 4X3LA 4YQ5A 4CNEA 2QMMA 4YQ9A 3OIIA 3KNUA 4YPYA 1V6ZA 1O6DA 4YQ4A 1UALA 3ILKA 3E5YA 1MXIA 4YPXA 4YQ7A 4KDZA 4E8BA 3AI9X 4YVIA 1V2XA 1VHYA 3BBEA 4YQCA 4YQ6A 3DCMX 2QWVA 5FAIA 2O3AA 4YQRA 3L8UA 3OIJA 3N4KA 1VH0A 5D9FA 4MCCA 4YQGA 4JAKA 4YQ8A 3NK7A 1UAMA 3GYQA 4J3CA 4JWHA 4YQQA 5GM8A 3KTYA 3NK6A 5GMBA 4L69A 4CNGA 1UAKA 3KY7A 1K3RA 3BBDA 4RG1A 2YY8A 4XBOA 3AIAA 2EGVA 1UAJA 4YQSA 1IPAA 4JWGA 4YQAA 1Z85A 1P9PA 4H3ZA 4YQOA 3IC6A 4MCBA 4FMWA 4YQ0A 2EGWA 1ZJRA 4H3YA 1X7OA 2HA8A 2Z0YA 3O7BA
chains in the Genus database with same CATH topology
4JALA 4YPWA 4X3MA 3IEFA 3QUVA 4YQ2A 1VHKA 3OINA 1NXZA 1TO0A 4YQDA 4YQIA 4YQ1A 4YVGA 4YQBA 4YPZA 3BBHA 3N4JA 4YQNA 4YQTA 3ONPA 1GZ0A 4JWJA 4YVHA 2CX8A 3KW2A 4IG6A 4JWFA 5CO4A 4MCDA 4YQPA 2V3JA 1J85A 4YQJA 3AXZA 2I6DA 4YVKA 4KGNA 1OY5A 5GMCA 4YQKA 4YQLA 4CNDA 4FAKA 1X7PA 2V3KA 4YVJA 1NS5A 4YQ3A 4PZKA 4CNFA 4X3LA 4YQ5A 4CNEA 2QMMA 4YQ9A 3OIIA 3KNUA 4YPYA 1V6ZA 1O6DA 4YQ4A 1UALA 3ILKA 3E5YA 1MXIA 4YPXA 4YQ7A 4KDZA 4E8BA 3AI9X 4YVIA 1V2XA 1VHYA 3BBEA 4YQCA 4YQ6A 3DCMX 2QWVA 5FAIA 2O3AA 4YQRA 3L8UA 3OIJA 3N4KA 1VH0A 5D9FA 4MCCA 4YQGA 4JAKA 4YQ8A 3NK7A 1UAMA 3GYQA 4J3CA 4JWHA 4YQQA 5GM8A 3KTYA 3NK6A 5GMBA 4L69A 4CNGA 1UAKA 3KY7A 1K3RA 3BBDA 4RG1A 2YY8A 4XBOA 3AIAA 2EGVA 1UAJA 4YQSA 1IPAA 4JWGA 4YQAA 1Z85A 1P9PA 4H3ZA 4YQOA 3IC6A 4MCBA 4FMWA 4YQ0A 2EGWA 1ZJRA 4H3YA 1X7OA 2HA8A 2Z0YA 3O7BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FMW A;  4JWG A;  4JWH A;  4JWJ A;  4JWF A; 
#chains in the Genus database with same CATH topology
 4JAL A;  4YPW A;  4X3M A;  3IEF A;  3QUV A;  4YQ2 A;  1VHK A;  3OIN A;  1NXZ A;  1TO0 A;  4YQD A;  4YQI A;  4YQ1 A;  4YVG A;  4YQB A;  4YPZ A;  3BBH A;  3N4J A;  4YQN A;  4YQT A;  3ONP A;  1GZ0 A;  4JWJ A;  4YVH A;  2CX8 A;  3KW2 A;  4IG6 A;  4JWF A;  5CO4 A;  4MCD A;  4YQP A;  2V3J A;  1J85 A;  4YQJ A;  3AXZ A;  2I6D A;  4YVK A;  4KGN A;  1OY5 A;  5GMC A;  4YQK A;  4YQL A;  4CND A;  4FAK A;  1X7P A;  2V3K A;  4YVJ A;  1NS5 A;  4YQ3 A;  4PZK A;  4CNF A;  4X3L A;  4YQ5 A;  4CNE A;  2QMM A;  4YQ9 A;  3OII A;  3KNU A;  4YPY A;  1V6Z A;  1O6D A;  4YQ4 A;  1UAL A;  3ILK A;  3E5Y A;  1MXI A;  4YPX A;  4YQ7 A;  4KDZ A;  4E8B A;  3AI9 X;  4YVI A;  1V2X A;  1VHY A;  3BBE A;  4YQC A;  4YQ6 A;  3DCM X;  2QWV A;  5FAI A;  2O3A A;  4YQR A;  3L8U A;  3OIJ A;  3N4K A;  1VH0 A;  5D9F A;  4MCC A;  4YQG A;  4JAK A;  4YQ8 A;  3NK7 A;  1UAM A;  3GYQ A;  4J3C A;  4JWH A;  4YQQ A;  5GM8 A;  3KTY A;  3NK6 A;  5GMB A;  4L69 A;  4CNG A;  1UAK A;  3KY7 A;  1K3R A;  3BBD A;  4RG1 A;  2YY8 A;  4XBO A;  3AIA A;  2EGV A;  1UAJ A;  4YQS A;  1IPA A;  4JWG A;  4YQA A;  1Z85 A;  1P9P A;  4H3Z A;  4YQO A;  3IC6 A;  4MCB A;  4FMW A;  4YQ0 A;  2EGW A;  1ZJR A;  4H3Y A;  1X7O A;  2HA8 A;  2Z0Y A;  3O7B A; 
#chains in the Genus database with same CATH homology
 4JAL A;  4YPW A;  4X3M A;  3IEF A;  3QUV A;  4YQ2 A;  1VHK A;  3OIN A;  1NXZ A;  1TO0 A;  4YQD A;  4YQI A;  4YQ1 A;  4YVG A;  4YQB A;  4YPZ A;  3BBH A;  3N4J A;  4YQN A;  4YQT A;  3ONP A;  1GZ0 A;  4JWJ A;  4YVH A;  2CX8 A;  3KW2 A;  4IG6 A;  4JWF A;  5CO4 A;  4MCD A;  4YQP A;  2V3J A;  1J85 A;  4YQJ A;  3AXZ A;  2I6D A;  4YVK A;  4KGN A;  1OY5 A;  5GMC A;  4YQK A;  4YQL A;  4CND A;  4FAK A;  1X7P A;  2V3K A;  4YVJ A;  1NS5 A;  4YQ3 A;  4PZK A;  4CNF A;  4X3L A;  4YQ5 A;  4CNE A;  2QMM A;  4YQ9 A;  3OII A;  3KNU A;  4YPY A;  1V6Z A;  1O6D A;  4YQ4 A;  1UAL A;  3ILK A;  3E5Y A;  1MXI A;  4YPX A;  4YQ7 A;  4KDZ A;  4E8B A;  3AI9 X;  4YVI A;  1V2X A;  1VHY A;  3BBE A;  4YQC A;  4YQ6 A;  3DCM X;  2QWV A;  5FAI A;  2O3A A;  4YQR A;  3L8U A;  3OIJ A;  3N4K A;  1VH0 A;  5D9F A;  4MCC A;  4YQG A;  4JAK A;  4YQ8 A;  3NK7 A;  1UAM A;  3GYQ A;  4J3C A;  4JWH A;  4YQQ A;  5GM8 A;  3KTY A;  3NK6 A;  5GMB A;  4L69 A;  4CNG A;  1UAK A;  3KY7 A;  1K3R A;  3BBD A;  4RG1 A;  2YY8 A;  4XBO A;  3AIA A;  2EGV A;  1UAJ A;  4YQS A;  1IPA A;  4JWG A;  4YQA A;  1Z85 A;  1P9P A;  4H3Z A;  4YQO A;  3IC6 A;  4MCB A;  4FMW A;  4YQ0 A;  2EGW A;  1ZJR A;  4H3Y A;  1X7O A;  2HA8 A;  2Z0Y A;  3O7B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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