|
19
|
99
|
5uovA |
Hiv-1 wild type protease with grl-1118a , an isophthalamide-derived p2-p3 ligand with the sulfonamide isostere as the p2' group |
|
18
|
99
|
5upjA |
Hiv-2 protease/u99283 complex |
|
18
|
99
|
5ultA |
Hiv-1 wild type protease with grl-100-13a (a crown-like oxotricyclic core as the p2-ligand with the sulfonamide isostere as the p2' group) |
|
16
|
99
|
5ufzA |
Hiv-1 protease complexed with inhibitor: (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl [(1s,2s)-1-(1-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}cyclopropyl)-1-hydroxy-3-phenylpropan-2-yl]carbamate |
|
20
|
99
|
5tysA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-142 |
|
20
|
99
|
5tyrA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-121 |
|
19
|
99
|
5t8hA |
Joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with amprenavir at ph 6.0 |
|
18
|
99
|
5t84A |
Hiv-1 protease, unbound subtype b l63p construct |
|
18
|
99
|
5kaoA |
Crystal structure of wild type hiv-1 protease in complex with grl-10413 |
|
18
|
99
|
5kr2A |
Protease pr5-sqv |
|
19
|
99
|
5jg1A |
Hiv-1 wild type protease with grl-031-14a (a adamantane p1-ligand with tetrahydropyrano-tetrahydrofuran in p2 and isobutylamine in p1') |
|
18
|
99
|
5kqyA |
Protease e35d-drv |
|
18
|
99
|
5ivsA |
Crystal structure of hiv protease complexed with methyl n-[(1s)-1-benzhydryl-2-[2-[2-[(2r,5s)-5-(benzylcarbamoyloxymethyl)morpholin-2-yl]ethyl]anilino]-2-oxo-ethyl]carbamate |
|
27
|
112
|
5fivA |
Structural studies of hiv and fiv proteases complexed with an efficient inhibitor of fiv pr |
|
19
|
99
|
5e5jA |
Joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with darunavir at ph 6.0 |
|
18
|
99
|
5e5kA |
Joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i,i47v,v82i) with darunavir at ph 4.3 |
|
18
|
99
|
5dguA |
Crystal structure of hiv-1 protease inhibitors containing substituted fused-tetrahydropyranyl tetrahydrofuran as p2-ligand grl-004-11a |
|
18
|
99
|
5dgwA |
Crystal structure of hiv-1 protease inhibitor grl-105-11a containing substituted fused-tetrahydropyranyl tetrahydrofuran as p2-ligand |
|
16
|
99
|
4yoaA |
Crsystal structure hiv-1 protease mdr769 l33f complexed with darunavir |
|
20
|
99
|
4yhqA |
Crystal structure of multidrug resistant clinical isolate pr20 with grl-5010a |
|
17
|
99
|
4yobA |
Crystal structure of apo hiv-1 protease mdr769 l33f |
|
17
|
99
|
5ahaA |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
17
|
99
|
5cooA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-085 |
|
17
|
99
|
5ahbA |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
16
|
99
|
5ahcA |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
16
|
99
|
5ah6A |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
19
|
99
|
5copA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-097 |
|
19
|
99
|
4ye3A |
Crystal structure of multidrug resistant hiv-1 protease clinical isolate pr20 with inhibitor grl-4410a |
|
16
|
99
|
5agzA |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
16
|
99
|
5ah8A |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
20
|
116
|
4ydfA |
Crystal structure of compound 9 in complex with htlv-1 protease |
|
16
|
99
|
5ah7A |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
21
|
116
|
4ydgA |
Crystal structure of compound 10 in complex with htlv-1 protease |
|
18
|
99
|
5conA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-015 |
|
19
|
99
|
5cokA |
X-ray crystal structure of wild type hiv-1 protease in complex with grl-0476 |
|
18
|
99
|
5ah9A |
Disubstituted bis-thf moieties as new p2 ligands in non-peptidal hiv- 1 protease inhibitors (ii) |
|
17
|
99
|
4upjA |
Human immunodeficiency virus type 2 protease mutant with lys 57 replaced by leu (k57l) complex with u097410 [4-hydroxy-3-[1-[3-[[[[(tert-butyloxycarbonyl) aminomethyl]carbonyl]amino]phenyl]propyl]coumarin |
|
18
|
99
|
4u7vA |
Structure of wild-type hiv protease in complex with degraded photosensitive inhibitor |
|
18
|
99
|
4tvhA |
Hiv protease (pr) dimer in closed form with tl-3 in active site and fragment ak-2097 in the outside/top of flap |
|
16
|
99
|
4tvgA |
Hiv protease (pr) dimer in closed form with pepstatin in active site and fragment ak-2097 in the outside/top of flap |
|
18
|
99
|
4u7qA |
Structure of wild-type hiv protease in complex with photosensitive inhibitor pdi-6 |
|
19
|
99
|
4u8wA |
Hiv-1 wild type protease with grl-050-10a (a gem-difluoro-bis-tetrahydrofuran as p2-ligand) |
|
17
|
99
|
4qj8A |
Crystal structure of inactive hiv-1 protease variant (i50v/a71v) in complex with p1-p6 substrate variant (p453l) |
|
20
|
99
|
4qj9A |
Crystal structure of inactive hiv-1 protease in complex with p1-p6 substrate variant (r452s) |
|
19
|
99
|
4rvxA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with non-peptidic inhibitor, grl079 |
|
18
|
99
|
4qj2A |
Crystal structure of inactive hiv-1 protease variant (i50v/a71v) in complex with wt p1-p6 substrate |
|
18
|
99
|
4rvjA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with amprenavir |
|
17
|
99
|
4rviA |
Crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with non-peptidic inhibitor, grl0519 |
|
18
|
99
|
4qj7A |
Crystal structure of inactive hiv-1 protease variant (i50v/a71v) in complex with p1-p6 substrate variant (r452s) |
|
17
|
99
|
4qj6A |
Crystal structure of inactive hiv-1 protease variant (i50v/a71v) in complex with p1-p6 substrate variant (l449f) |
