1CMXA

Structural basis for the specificity of ubiquitin c-terminal hydrolases
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
Knots found
sequence length
229
structure length
214
Chain Sequence
RAVVPIESNPEVFTNFAHKLGLKNEWAYFDIYSLTEPELLAFLPRPVKAIVLLFPINDVIWFKQSVKNACGLYAILHSLSNNQSLLEPGSDLDNFLKSQSDTSSSKNRFDDVTTDQFVLNVIKENVQTFSTGQSEAPEATADTNLHYITYVEENGGIFELDGRNLSGPLYLGKSDPTATDLIEQELVRVRVASYMENANEEDVLNFAMLGLGPN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the specificity of ubiquitin C-terminal hydrolases.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords PROTEIN (UBIQUITIN YUH1-UBAL)
total genus 69
structure length 214
sequence length 229
chains with identical sequence C
other databases KnotProt 2.0: K -31
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 1999-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01088 Peptidase_C12 Ubiquitin carboxyl-terminal hydrolase, family 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1cmxA00
3RIIA 2LENA 4UEMA 3IHRA 1XD3A 1CMXA 3A7SA 4JKJA 1UCHA 3KW5A 4IG7A 3IRTA 4UELA 3RISA 4DM9A 3KVFA 3TB3A 3IFWA 2ETLA 4I6NA
chains in the Genus database with same CATH superfamily
3RIIA 2LENA 4UEMA 3IHRA 1XD3A 1CMXA 3A7SA 4JKJA 1UCHA 3KW5A 4IG7A 3IRTA 4UELA 3RISA 4DM9A 3KVFA 3TB3A 3IFWA 2ETLA 4I6NA
chains in the Genus database with same CATH topology
3RIIA 2LENA 4UEMA 3IHRA 1XD3A 1CMXA 3A7SA 4JKJA 1UCHA 3KW5A 4IG7A 3IRTA 4UELA 3RISA 4DM9A 3KVFA 3TB3A 3IFWA 2ETLA 4I6NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RII A;  2LEN A;  4UEM A;  3IHR A;  1XD3 A;  1CMX A;  3A7S A;  4JKJ A;  1UCH A;  3KW5 A;  4IG7 A;  3IRT A;  4UEL A;  3RIS A;  4DM9 A;  3KVF A;  3TB3 A;  3IFW A;  2ETL A;  4I6N A; 
#chains in the Genus database with same CATH topology
 3RII A;  2LEN A;  4UEM A;  3IHR A;  1XD3 A;  1CMX A;  3A7S A;  4JKJ A;  1UCH A;  3KW5 A;  4IG7 A;  3IRT A;  4UEL A;  3RIS A;  4DM9 A;  3KVF A;  3TB3 A;  3IFW A;  2ETL A;  4I6N A; 
#chains in the Genus database with same CATH homology
 3RII A;  2LEN A;  4UEM A;  3IHR A;  1XD3 A;  1CMX A;  3A7S A;  4JKJ A;  1UCH A;  3KW5 A;  4IG7 A;  3IRT A;  4UEL A;  3RIS A;  4DM9 A;  3KVF A;  3TB3 A;  3IFW A;  2ETL A;  4I6N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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