1KICA

Inosine-adenosine-guanosine preferring nucleoside hydrolase from trypanosoma vivax: asp10ala mutant in complex with inosine
Total Genus 122
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
327
structure length
317
Chain Sequence
SAKNVVLDHAGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma vivax
molecule keywords inosine-adenosine-guanosine preferring nucleoside hydrolase
total genus 122
structure length 317
sequence length 327
chains with identical sequence B
ec nomenclature ec 3.2.2.1: Purine nucleosidase.
pdb deposition date 2001-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 1kicA00
3T8IA 2FF1A 1HOZA 3B9GA 3MKMA 1MASA 4I70A 4KL0A 1HP0A 3MKNA 2YHGA 1KICA 1Q8FA 2FF2A 3B9XA 4I74A 4I72A 3FZ0A 1R4FA 2MASA 3G5IA 4I71A 5TSQA 2C40A 3EPWA 1EZRA 1YOEA 4I73A 4KPNA 3EPXA 4I75A 4KPOA 1KIEA 4P5FA 3T8JA 4WR2A
chains in the Genus database with same CATH superfamily
3T8IA 2FF1A 1HOZA 3B9GA 3MKMA 1MASA 4I70A 4KL0A 1HP0A 3MKNA 2YHGA 1KICA 1Q8FA 2FF2A 3B9XA 4I74A 4I72A 3FZ0A 1R4FA 2MASA 3G5IA 4I71A 5TSQA 2C40A 3EPWA 1EZRA 1YOEA 4I73A 4KPNA 3EPXA 4I75A 4KPOA 1KIEA 4P5FA 3T8JA 4WR2A
chains in the Genus database with same CATH topology
3T8IA 2FF1A 1HOZA 3B9GA 3MKMA 1MASA 4I70A 4KL0A 1HP0A 3MKNA 2YHGA 1KICA 1Q8FA 2FF2A 3B9XA 4I74A 4I72A 3FZ0A 1R4FA 2MASA 3G5IA 4I71A 5TSQA 2C40A 3EPWA 1EZRA 1YOEA 4I73A 4KPNA 3EPXA 4I75A 4KPOA 1KIEA 4P5FA 3T8JA 4WR2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3T8I A;  2FF1 A;  1HOZ A;  3B9G A;  3MKM A;  1MAS A;  4I70 A;  4KL0 A;  1HP0 A;  3MKN A;  2YHG A;  1KIC A;  1Q8F A;  2FF2 A;  3B9X A;  4I74 A;  4I72 A;  3FZ0 A;  1R4F A;  2MAS A;  3G5I A;  4I71 A;  5TSQ A;  2C40 A;  3EPW A;  1EZR A;  1YOE A;  4I73 A;  4KPN A;  3EPX A;  4I75 A;  4KPO A;  1KIE A;  4P5F A;  3T8J A;  4WR2 A; 
#chains in the Genus database with same CATH topology
 3T8I A;  2FF1 A;  1HOZ A;  3B9G A;  3MKM A;  1MAS A;  4I70 A;  4KL0 A;  1HP0 A;  3MKN A;  2YHG A;  1KIC A;  1Q8F A;  2FF2 A;  3B9X A;  4I74 A;  4I72 A;  3FZ0 A;  1R4F A;  2MAS A;  3G5I A;  4I71 A;  5TSQ A;  2C40 A;  3EPW A;  1EZR A;  1YOE A;  4I73 A;  4KPN A;  3EPX A;  4I75 A;  4KPO A;  1KIE A;  4P5F A;  3T8J A;  4WR2 A; 
#chains in the Genus database with same CATH homology
 3T8I A;  2FF1 A;  1HOZ A;  3B9G A;  3MKM A;  1MAS A;  4I70 A;  4KL0 A;  1HP0 A;  3MKN A;  2YHG A;  1KIC A;  1Q8F A;  2FF2 A;  3B9X A;  4I74 A;  4I72 A;  3FZ0 A;  1R4F A;  2MAS A;  3G5I A;  4I71 A;  5TSQ A;  2C40 A;  3EPW A;  1EZR A;  1YOE A;  4I73 A;  4KPN A;  3EPX A;  4I75 A;  4KPO A;  1KIE A;  4P5F A;  3T8J A;  4WR2 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...