1Q8F | Genus

Total Genus 108

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	108
sequence length	308
structure length	308
Chain Sequence	KRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGDTGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFTPSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDTDWFWGLVEECVRGYI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 308 atoms

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308 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy. pubmed doi rcsb
molecule keywords	Pyrimidine nucleoside hydrolase
molecule tags	Hydrolase
source organism	Escherichia coli
total genus	108
structure length	308
sequence length	308
chains with identical sequence	B, C, D
ec nomenclature	ec 3.2.2.8: Ribosylpyrimidine nucleosidase.
pdb deposition date	2003-08-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	1q8fA00

3EPXA 1EZRA 1YOEA 4I70A 3MKNA 2MASA 2FF1A 3T8JA 2FF2A 1Q8FA 1KICA 4KPNA 3B9XA 1MASA 4I75A 4I72A 5TSQA 1HP0A 4WR2A 4I73A 4P5FA 4KPOA 4I71A 2YHGA 3B9GA 4I74A 1HOZA 3MKMA 1KIEA 3T8IA 2C40A 3G5IA 3EPWA 3FZ0A 4KL0A 1R4FA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3EPX A;  1EZR A;  1YOE A;  4I70 A;  3MKN A;  2MAS A;  2FF1 A;  3T8J A;  2FF2 A;  1Q8F A;  1KIC A;  4KPN A;  3B9X A;  1MAS A;  4I75 A;  4I72 A;  5TSQ A;  1HP0 A;  4WR2 A;  4I73 A;  4P5F A;  4KPO A;  4I71 A;  2YHG A;  3B9G A;  4I74 A;  1HOZ A;  3MKM A;  1KIE A;  3T8I A;  2C40 A;  3G5I A;  3EPW A;  3FZ0 A;  4KL0 A;  1R4F A; 
#chains in the Genus database with same CATH topology
 3EPX A;  1EZR A;  1YOE A;  4I70 A;  3MKN A;  2MAS A;  2FF1 A;  3T8J A;  2FF2 A;  1Q8F A;  1KIC A;  4KPN A;  3B9X A;  1MAS A;  4I75 A;  4I72 A;  5TSQ A;  1HP0 A;  4WR2 A;  4I73 A;  4P5F A;  4KPO A;  4I71 A;  2YHG A;  3B9G A;  4I74 A;  1HOZ A;  3MKM A;  1KIE A;  3T8I A;  2C40 A;  3G5I A;  3EPW A;  3FZ0 A;  4KL0 A;  1R4F A; 
#chains in the Genus database with same CATH homology
 3EPX A;  1EZR A;  1YOE A;  4I70 A;  3MKN A;  2MAS A;  2FF1 A;  3T8J A;  2FF2 A;  1Q8F A;  1KIC A;  4KPN A;  3B9X A;  1MAS A;  4I75 A;  4I72 A;  5TSQ A;  1HP0 A;  4WR2 A;  4I73 A;  4P5F A;  4KPO A;  4I71 A;  2YHG A;  3B9G A;  4I74 A;  1HOZ A;  3MKM A;  1KIE A;  3T8I A;  2C40 A;  3G5I A;  3EPW A;  3FZ0 A;  4KL0 A;  1R4F A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1Q8FA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations