1UCH | Genus

Total Genus 69

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	69
Knots found	KnotProt 2.0: K -5₂ -3₁ -3₁
sequence length	226
structure length	206
Chain Sequence	RWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESVSMSPEERARYLENYDAIRVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 206 atoms

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206 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Cysteine protease
source organism	Homo sapiens
publication title	Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution. pubmed doi rcsb
molecule keywords	UBIQUITIN C-TERMINAL HYDROLASE UCH-L3
total genus	69
structure length	206
sequence length	226
other databases	KnotProt 2.0: K -5₂ -3₁ -3₁
ec nomenclature	ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date	1997-10-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01088	Peptidase_C12	Ubiquitin carboxyl-terminal hydrolase, family 1

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.532.10	Alpha Beta	3-Layer(aba) Sandwich	Ubiquitin C-terminal Hydrolase UCH-l3	Peptidase C12, ubiquitin carboxyl-terminal hydrolase	1uchA00

3IFWA 3IHRA 4I6NA 3KW5A 3IRTA 3A7SA 4UELA 4UEMA 3RISA 2LENA 3TB3A 1UCHA 3RIIA 4IG7A 1XD3A 3KVFA 4JKJA 2ETLA 4DM9A 1CMXA
chains in the Genus database with same CATH superfamily

3IFWA 3IHRA 4I6NA 3KW5A 3IRTA 3A7SA 4UELA 4UEMA 3RISA 2LENA 3TB3A 1UCHA 3RIIA 4IG7A 1XD3A 3KVFA 4JKJA 2ETLA 4DM9A 1CMXA
chains in the Genus database with same CATH topology

3IFWA 3IHRA 4I6NA 3KW5A 3IRTA 3A7SA 4UELA 4UEMA 3RISA 2LENA 3TB3A 1UCHA 3RIIA 4IG7A 1XD3A 3KVFA 4JKJA 2ETLA 4DM9A 1CMXA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3IFW A;  3IHR A;  4I6N A;  3KW5 A;  3IRT A;  3A7S A;  4UEL A;  4UEM A;  3RIS A;  2LEN A;  3TB3 A;  1UCH A;  3RII A;  4IG7 A;  1XD3 A;  3KVF A;  4JKJ A;  2ETL A;  4DM9 A;  1CMX A; 
#chains in the Genus database with same CATH topology
 3IFW A;  3IHR A;  4I6N A;  3KW5 A;  3IRT A;  3A7S A;  4UEL A;  4UEM A;  3RIS A;  2LEN A;  3TB3 A;  1UCH A;  3RII A;  4IG7 A;  1XD3 A;  3KVF A;  4JKJ A;  2ETL A;  4DM9 A;  1CMX A; 
#chains in the Genus database with same CATH homology
 3IFW A;  3IHR A;  4I6N A;  3KW5 A;  3IRT A;  3A7S A;  4UEL A;  4UEM A;  3RIS A;  2LEN A;  3TB3 A;  1UCH A;  3RII A;  4IG7 A;  1XD3 A;  3KVF A;  4JKJ A;  2ETL A;  4DM9 A;  1CMX A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1UCHA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations