2AQBA

Structure-activity relationships at the 5-position of thiolactomycin: an intact 5(r)-isoprene unit is required for activity against the condensing enzymes from mycobacterium tuberculosis and escherchia coli
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
404
structure length
404
Chain Sequence
MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Relationships at the 5-Position of Thiolactomycin: An Intact (5R)-Isoprene Unit Is Required for Activity against the Condensing Enzymes from Mycobacterium tuberculosis and Escherichia coli
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords 3-oxoacyl-[acyl-carrier-protein] synthase I
total genus 143
structure length 404
sequence length 404
chains with identical sequence B, C, D
ec nomenclature ec 2.3.1.41: Beta-ketoacyl-[acyl-carrier-protein] synthase I.
pdb deposition date 2005-08-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00109 ketoacyl-synt Beta-ketoacyl synthase, N-terminal domain
A PF02801 Ketoacyl-synt_C Beta-ketoacyl synthase, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.47.10 Alpha Beta 3-Layer(aba) Sandwich Peroxisomal Thiolase; Chain A, domain 1 Peroxisomal Thiolase; Chain A, domain 1 2aqbA01
3.40.47.10 Alpha Beta 3-Layer(aba) Sandwich Peroxisomal Thiolase; Chain A, domain 1 Peroxisomal Thiolase; Chain A, domain 1 2aqbA02
5HWQA 3ZBGA 4JARA 4JRMA 4JV3A 3IL6A 3S1ZA 5BQSA 1FJ4A 2F82A 2WL4D 2IB7A 4OPFA 4QYRA 1UB7A 5BZ4A 3IL3A 4C2JA 3S20A 1WDKC 3LRFA 2QNXA 5LOTA 5E5NA 1B3NA 1EK4A 2GYOA 2D52A 4KC5A 3U0EA 1NL7A 3WXZA 4U4EA 2BUIA 2VTZA 1AFWA 4UBUA 2C7ZA 5C1JA 4NZSA 3TSYA 4LS5A 4DDOA 4DD5A 3IL5A 1WDLC 3OV3A 4C2KA 5BNSA 5HWRA 4TKTA 4B7VA 3OV2A 2BYWA 3ZBKA 5AB5A 1PXTA 4X9OA 2WL4A 1TEDA 1XPKC 3T6SB 3WY0A 2VU0A 2WKUA 3HHDA 4B3HC 4WUMA 4UBWA 2VBAA 4B3JC 1XESA 1EBLA 2VB7C 2FA0A 1CMLA 2WL5A 2IBUA 2D3MA 1OXHA 3OYTA 1EE0A 2BYZA 2X3EA 4JAQA 2VB8A 1WL4A 3U0FA 2P8UA 3S3LA 4XL3A 3T8EA 1W0IA 3IL7A 3E1HA 4B3IC 2WL6A 3S21A 2BYXA 3EUTA 1DLVA 4YXVA 4WYSA 1G5XA 4XL4A 5F38B 2IBWA 2VU2A 2GQDA 3AWKA 2IBYA 4LS7A 5CBQA 2IWYA 4C6XA 1J3NA 4X9KA 4XS7A 1FJ8A 1U0UA 4ZDNA 2D51A 3V4XA 1XETA 2VZ9A 4UBTA 2GFWA 1M1OA 2WGGA 1I8BA 4WZUA 1YSLA 1U6EA 3V4NA 3E60A 4YZOA 4F32A 1QFLA 3A5QA 3H77A 5F38C 1MZSA 1OU6A 5KP2A 4N45A 3SVKA 2IB8A 3IL4A 2RJTA 2QNZA 4LS8A 3GWEA 3VS9A 4UBVA 1U0WA 4C70A 2P0UA 3G11A 4EWGA 3A5RA 2EFTA 4JAPA 5AB7A 4XSBA 3H78A 4NA1A 1DLUA 1CGKA 1WDMC 1BQ6A 3ROWA 2H84A 4R8EA 4YUFA 4WKYA 3T5YA 1TQYA 1M1MA 2C7YA 5F0VA 5LP7A 2BYYA 4RYBA 2FA3A 4JAOA 5SXOA 3WD8A 2WGEA 1I89A 1TXTA 4WYRA 1M3ZA 4NA2A 2WKTC 1CHWA 3GOAA 3SS6A 4Z37A 5LNQA 5KP7A 2WUAA 2AQ7A 4JATA 5TT4A 1HNJA 4C72A 2ALMA 5LD8A 3KZUA 4YJYA 2AHBA 2QX1A 4YUCA 1D6IA 1HNHA 1Z1FA 4E1LA 5BNMA 2WU9A 4KTIA 5HWPA 2EBDA 3ZBNA 1XPMA 1XPKA 1U6SA 4XSAA 4JPFA 3WXYA 4JGAA 3VS8A 4C6UA 2VB7A 1I88A 1Z1EA 1DM3A 3ZBLA 2F9AA 1U0VA 4C6VA 1M3KA 2GFXA 3S23A 1TVZA 4XL2A 4JB6A 4NHDA 4KTMA 2HG4A 2GFVA 1BI5A 1TEEA 2AJ9A 1MZJA 1U0MA 4EFIA 5BY7A 2WYAA 5DWZC 4KU5A 2HDBA 3HO9A 3V7IA 3AWJA 4X0OA 4BI9A 2WL4B 2QO3A 3O04A 4EWPA 4QAVA 1D6HA 2IB9A 1OX0A 4N44A 4EGVA 4C73A 4O99A 4LS6A 3SQZA 4C71A 1ZOWA 5HWOA 2QO1A 2BZ3A 1CGZA 1D6FA 5BYVA 3HO2A 4JD3A 1HN9A 1HNDA 4OPEA 1E5MA 4JRHA 4YXTA 5F38A 3WD7A 5AB4A 2WL4C 4KU3A 5AB6A 3A5SA 2GP6A 1QLVA 2BUHA 2BZ4A 4DFEA 3H76A 1M4TA 2WL5C 2UV8A 5BNRA 2WKVA 3IL9A 4XOXA 2IIKA 2IX4A 3HNZA 4O9CA 2WGDA 4C6WA 3G0YA 4YXQA 1I86A 1HNKA 4XS9A 2D3TC 4C6ZA 1ULQA 1DD8A 4OQJA 1HZPA 2IWZA 5KP5A 4BIAA 1JWXA 2QO0A 5KP6A 2WGFA 4KU2A 4X0OD 3OITA 1YSLB 1X9EA 2WKTA 2VZ8A 3LEDA 4Z8DA 3I8PA 1XPLA 3EUQA 1WL5A 1F91A 3FK5A 4B0NA 2C9HA 3MQDA 4V2PA 4NA3A 4ZRCA 4Z19A 2AQBA 2GFYA 3EUOA 2F2SA 4YLTA 5F38D 2VU1A 1M1TA 3T6SA 1H4FA 4O9AA 2VB9A 3LEHA 3GWAA 1M4SA 4W61A 1KASA 5KP8A 3T5YB 1TQYB 2QNYA 3ALEA
chains in the Genus database with same CATH superfamily
5HWQA 3ZBGA 4JARA 4JRMA 4JV3A 3IL6A 3S1ZA 5BQSA 1FJ4A 2F82A 2WL4D 2IB7A 4OPFA 4QYRA 1UB7A 5BZ4A 3IL3A 4C2JA 3S20A 1WDKC 3LRFA 2QNXA 5LOTA 5E5NA 1B3NA 1EK4A 2GYOA 2D52A 4KC5A 3U0EA 1NL7A 3WXZA 4U4EA 2BUIA 2VTZA 1AFWA 4UBUA 2C7ZA 5C1JA 4NZSA 3TSYA 4LS5A 4DDOA 4DD5A 3IL5A 1WDLC 3OV3A 4C2KA 5BNSA 5HWRA 4TKTA 4B7VA 3OV2A 2BYWA 3ZBKA 5AB5A 1PXTA 4X9OA 2WL4A 1TEDA 1XPKC 3T6SB 3WY0A 2VU0A 2WKUA 3HHDA 4B3HC 4WUMA 4UBWA 2VBAA 4B3JC 1XESA 1EBLA 2VB7C 2FA0A 1CMLA 2WL5A 2IBUA 2D3MA 1OXHA 3OYTA 1EE0A 2BYZA 2X3EA 4JAQA 2VB8A 1WL4A 3U0FA 2P8UA 3S3LA 4XL3A 3T8EA 1W0IA 3IL7A 3E1HA 4B3IC 2WL6A 3S21A 2BYXA 3EUTA 1DLVA 4YXVA 4WYSA 1G5XA 4XL4A 5F38B 2IBWA 2VU2A 2GQDA 3AWKA 2IBYA 4LS7A 5CBQA 2IWYA 4C6XA 1J3NA 4X9KA 4XS7A 1FJ8A 1U0UA 4ZDNA 2D51A 3V4XA 1XETA 2VZ9A 4UBTA 2GFWA 1M1OA 2WGGA 1I8BA 4WZUA 1YSLA 1U6EA 3V4NA 3E60A 4YZOA 4F32A 1QFLA 3A5QA 3H77A 5F38C 1MZSA 1OU6A 5KP2A 4N45A 3SVKA 2IB8A 3IL4A 2RJTA 2QNZA 4LS8A 3GWEA 3VS9A 4UBVA 1U0WA 4C70A 2P0UA 3G11A 4EWGA 3A5RA 2EFTA 4JAPA 5AB7A 4XSBA 3H78A 4NA1A 1DLUA 1CGKA 1WDMC 1BQ6A 3ROWA 2H84A 4R8EA 4YUFA 4WKYA 3T5YA 1TQYA 1M1MA 2C7YA 5F0VA 5LP7A 2BYYA 4RYBA 2FA3A 4JAOA 5SXOA 3WD8A 2WGEA 1I89A 1TXTA 4WYRA 1M3ZA 4NA2A 2WKTC 1CHWA 3GOAA 3SS6A 4Z37A 5LNQA 5KP7A 2WUAA 2AQ7A 4JATA 5TT4A 1HNJA 4C72A 2ALMA 5LD8A 3KZUA 4YJYA 2AHBA 2QX1A 4YUCA 1D6IA 1HNHA 1Z1FA 4E1LA 5BNMA 2WU9A 4KTIA 5HWPA 2EBDA 3ZBNA 1XPMA 1XPKA 1U6SA 4XSAA 4JPFA 3WXYA 4JGAA 3VS8A 4C6UA 2VB7A 1I88A 1Z1EA 1DM3A 3ZBLA 2F9AA 1U0VA 4C6VA 1M3KA 2GFXA 3S23A 1TVZA 4XL2A 4JB6A 4NHDA 4KTMA 2HG4A 2GFVA 1BI5A 1TEEA 2AJ9A 1MZJA 1U0MA 4EFIA 5BY7A 2WYAA 5DWZC 4KU5A 2HDBA 3HO9A 3V7IA 3AWJA 4X0OA 4BI9A 2WL4B 2QO3A 3O04A 4EWPA 4QAVA 1D6HA 2IB9A 1OX0A 4N44A 4EGVA 4C73A 4O99A 4LS6A 3LMAA 3SQZA 4C71A 1ZOWA 5HWOA 2QO1A 2BZ3A 1CGZA 1D6FA 5BYVA 3HO2A 4JD3A 1HN9A 1HNDA 4OPEA 1E5MA 4JRHA 4YXTA 5F38A 3WD7A 5AB4A 2WL4C 4KU3A 5AB6A 3A5SA 2GP6A 1QLVA 2BUHA 2BZ4A 4DFEA 3H76A 1M4TA 2WL5C 2UV8A 5BNRA 2WKVA 3IL9A 4XOXA 2IIKA 2IX4A 3HNZA 4O9CA 2WGDA 4C6WA 3G0YA 4YXQA 1I86A 1HNKA 4XS9A 2D3TC 4C6ZA 1ULQA 1DD8A 4OQJA 1HZPA 2IWZA 5KP5A 4BIAA 1JWXA 2QO0A 5KP6A 2WGFA 4KU2A 4X0OD 3OITA 1YSLB 1X9EA 2WKTA 2VZ8A 3LEDA 4Z8DA 3I8PA 1XPLA 3EUQA 1WL5A 1F91A 3FK5A 4B0NA 2C9HA 3MQDA 4V2PA 4NA3A 3LM6A 4ZRCA 4Z19A 2AQBA 2GFYA 3EUOA 2F2SA 4YLTA 5F38D 2VU1A 1M1TA 3T6SA 1H4FA 4O9AA 2VB9A 3LEHA 3GWAA 1M4SA 4W61A 1KASA 5KP8A 3T5YB 1TQYB 2QNYA 3ALEA
chains in the Genus database with same CATH topology
5HWQA 3ZBGA 4JARA 4JRMA 4JV3A 3IL6A 3S1ZA 5BQSA 1FJ4A 2F82A 2WL4D 2IB7A 4OPFA 4QYRA 1UB7A 5BZ4A 3IL3A 4C2JA 3S20A 1WDKC 3LRFA 2QNXA 5LOTA 5E5NA 1B3NA 1EK4A 2GYOA 2D52A 4KC5A 3U0EA 1NL7A 3WXZA 4U4EA 2BUIA 2VTZA 1AFWA 4UBUA 2C7ZA 5C1JA 4NZSA 3TSYA 4LS5A 4DDOA 4DD5A 3IL5A 1WDLC 3OV3A 4C2KA 5BNSA 5HWRA 4TKTA 4B7VA 3OV2A 2BYWA 3ZBKA 5AB5A 1PXTA 4X9OA 2WL4A 1TEDA 1XPKC 3T6SB 3WY0A 2VU0A 2WKUA 3HHDA 4B3HC 4WUMA 4UBWA 2VBAA 4B3JC 1XESA 1EBLA 2VB7C 2FA0A 1CMLA 2WL5A 2IBUA 2D3MA 1OXHA 3OYTA 1EE0A 2BYZA 2X3EA 4JAQA 2VB8A 1WL4A 3U0FA 2P8UA 3S3LA 4XL3A 3T8EA 1W0IA 3IL7A 3E1HA 4B3IC 2WL6A 3S21A 2BYXA 3EUTA 1DLVA 4YXVA 4WYSA 1G5XA 4XL4A 5F38B 2IBWA 2VU2A 2GQDA 3AWKA 2IBYA 4LS7A 5CBQA 2IWYA 4C6XA 1J3NA 4X9KA 4XS7A 1FJ8A 1U0UA 4ZDNA 2D51A 3V4XA 1XETA 2VZ9A 4UBTA 2GFWA 1M1OA 2WGGA 1I8BA 4WZUA 1YSLA 1U6EA 3V4NA 3E60A 4YZOA 4F32A 1QFLA 3A5QA 3H77A 5F38C 1MZSA 1OU6A 5KP2A 4N45A 3SVKA 2IB8A 3IL4A 2RJTA 2QNZA 4LS8A 3GWEA 3VS9A 4UBVA 1U0WA 4C70A 2P0UA 3G11A 4EWGA 3A5RA 2EFTA 4JAPA 5AB7A 4XSBA 3H78A 4NA1A 1DLUA 1CGKA 1WDMC 1BQ6A 3ROWA 2H84A 4R8EA 4YUFA 4WKYA 3T5YA 1TQYA 1M1MA 2C7YA 5F0VA 5LP7A 2BYYA 4RYBA 2FA3A 4JAOA 5SXOA 3WD8A 2WGEA 1I89A 1TXTA 4WYRA 1M3ZA 4NA2A 2WKTC 1CHWA 3GOAA 3SS6A 4Z37A 5LNQA 5KP7A 2WUAA 2AQ7A 4JATA 5TT4A 1HNJA 4C72A 2ALMA 5LD8A 3KZUA 4YJYA 2AHBA 2QX1A 4YUCA 1D6IA 1HNHA 1Z1FA 4E1LA 5BNMA 2WU9A 4KTIA 5HWPA 2EBDA 3ZBNA 1XPMA 1XPKA 1U6SA 4XSAA 4JPFA 3WXYA 4JGAA 3VS8A 4C6UA 2VB7A 1I88A 1Z1EA 1DM3A 3ZBLA 2F9AA 1U0VA 4C6VA 1M3KA 2GFXA 3S23A 1TVZA 4XL2A 4JB6A 4NHDA 4KTMA 2HG4A 2GFVA 1BI5A 1TEEA 2AJ9A 1MZJA 1U0MA 4EFIA 5BY7A 2WYAA 5DWZC 4KU5A 2HDBA 3HO9A 3V7IA 3AWJA 4X0OA 4BI9A 2WL4B 2QO3A 3O04A 4EWPA 4QAVA 1D6HA 2IB9A 1OX0A 4N44A 4EGVA 4C73A 4O99A 4LS6A 3LMAA 3SQZA 4C71A 1ZOWA 5HWOA 2QO1A 2BZ3A 1CGZA 1D6FA 5BYVA 3HO2A 4JD3A 1HN9A 1HNDA 4OPEA 1E5MA 4JRHA 4YXTA 5F38A 3WD7A 5AB4A 2WL4C 4KU3A 5AB6A 3A5SA 2GP6A 1QLVA 2BUHA 2BZ4A 4DFEA 3H76A 1M4TA 2WL5C 2UV8A 5BNRA 2WKVA 3IL9A 4XOXA 2IIKA 2IX4A 3HNZA 4O9CA 2WGDA 4C6WA 3G0YA 4YXQA 1I86A 1HNKA 4XS9A 2D3TC 4C6ZA 1ULQA 1DD8A 4OQJA 1HZPA 2IWZA 5KP5A 4BIAA 1JWXA 2QO0A 5KP6A 2WGFA 4KU2A 4X0OD 3OITA 1YSLB 1X9EA 2WKTA 2VZ8A 3LEDA 4Z8DA 3I8PA 1XPLA 3EUQA 1WL5A 1F91A 3FK5A 4B0NA 2C9HA 3MQDA 4V2PA 4NA3A 3LM6A 4ZRCA 4Z19A 2AQBA 2GFYA 3EUOA 2F2SA 4YLTA 5F38D 2VU1A 1M1TA 3T6SA 1H4FA 4O9AA 2VB9A 3LEHA 3GWAA 1M4SA 4W61A 1KASA 5KP8A 3T5YB 1TQYB 2QNYA 3ALEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HWQ A;  3ZBG A;  4JAR A;  4JRM A;  4JV3 A;  3IL6 A;  3S1Z A;  5BQS A;  1FJ4 A;  2F82 A;  2WL4 D;  2IB7 A;  4OPF A;  4QYR A;  1UB7 A;  5BZ4 A;  3IL3 A;  4C2J A;  3S20 A;  1WDK C;  3LRF A;  2QNX A;  5LOT A;  5E5N A;  1B3N A;  1EK4 A;  2GYO A;  2D52 A;  4KC5 A;  3U0E A;  1NL7 A;  3WXZ A;  4U4E A;  2BUI A;  2VTZ A;  1AFW A;  4UBU A;  2C7Z A;  5C1J A;  4NZS A;  3TSY A;  4LS5 A;  4DDO A;  4DD5 A;  3IL5 A;  1WDL C;  3OV3 A;  4C2K A;  5BNS A;  5HWR A;  4TKT A;  4B7V A;  3OV2 A;  2BYW A;  3ZBK A;  5AB5 A;  1PXT A;  4X9O A;  2WL4 A;  1TED A;  1XPK C;  3T6S B;  3WY0 A;  2VU0 A;  2WKU A;  3HHD A;  4B3H C;  4WUM A;  4UBW A;  2VBA A;  4B3J C;  1XES A;  1EBL A;  2VB7 C;  2FA0 A;  1CML A;  2WL5 A;  2IBU A;  2D3M A;  1OXH A;  3OYT A;  1EE0 A;  2BYZ A;  2X3E A;  4JAQ A;  2VB8 A;  1WL4 A;  3U0F A;  2P8U A;  3S3L A;  4XL3 A;  3T8E A;  1W0I A;  3IL7 A;  3E1H A;  4B3I C;  2WL6 A;  3S21 A;  2BYX A;  3EUT A;  1DLV A;  4YXV A;  4WYS A;  1G5X A;  4XL4 A;  5F38 B;  2IBW A;  2VU2 A;  2GQD A;  3AWK A;  2IBY A;  4LS7 A;  5CBQ A;  2IWY A;  4C6X A;  1J3N A;  4X9K A;  4XS7 A;  1FJ8 A;  1U0U A;  4ZDN A;  2D51 A;  3V4X A;  1XET A;  2VZ9 A;  4UBT A;  2GFW A;  1M1O A;  2WGG A;  1I8B A;  4WZU A;  1YSL A;  1U6E A;  3V4N A;  3E60 A;  4YZO A;  4F32 A;  1QFL A;  3A5Q A;  3H77 A;  5F38 C;  1MZS A;  1OU6 A;  5KP2 A;  4N45 A;  3SVK A;  2IB8 A;  3IL4 A;  2RJT A;  2QNZ A;  4LS8 A;  3GWE A;  3VS9 A;  4UBV A;  1U0W A;  4C70 A;  2P0U A;  3G11 A;  4EWG A;  3A5R A;  2EFT A;  4JAP A;  5AB7 A;  4XSB A;  3H78 A;  4NA1 A;  1DLU A;  1CGK A;  1WDM C;  1BQ6 A;  3ROW A;  2H84 A;  4R8E A;  4YUF A;  4WKY A;  3T5Y A;  1TQY A;  1M1M A;  2C7Y A;  5F0V A;  5LP7 A;  2BYY A;  4RYB A;  2FA3 A;  4JAO A;  5SXO A;  3WD8 A;  2WGE A;  1I89 A;  1TXT A;  4WYR A;  1M3Z A;  4NA2 A;  2WKT C;  1CHW A;  3GOA A;  3SS6 A;  4Z37 A;  5LNQ A;  5KP7 A;  2WUA A;  2AQ7 A;  4JAT A;  5TT4 A;  1HNJ A;  4C72 A;  2ALM A;  5LD8 A;  3KZU A;  4YJY A;  2AHB A;  2QX1 A;  4YUC A;  1D6I A;  1HNH A;  1Z1F A;  4E1L A;  5BNM A;  2WU9 A;  4KTI A;  5HWP A;  2EBD A;  3ZBN A;  1XPM A;  1XPK A;  1U6S A;  4XSA A;  4JPF A;  3WXY A;  4JGA A;  3VS8 A;  4C6U A;  2VB7 A;  1I88 A;  1Z1E A;  1DM3 A;  3ZBL A;  2F9A A;  1U0V A;  4C6V A;  1M3K A;  2GFX A;  3S23 A;  1TVZ A;  4XL2 A;  4JB6 A;  4NHD A;  4KTM A;  2HG4 A;  2GFV A;  1BI5 A;  1TEE A;  2AJ9 A;  1MZJ A;  1U0M A;  4EFI A;  5BY7 A;  2WYA A;  5DWZ C;  4KU5 A;  2HDB A;  3HO9 A;  3V7I A;  3AWJ A;  4X0O A;  4BI9 A;  2WL4 B;  2QO3 A;  3O04 A;  4EWP A;  4QAV A;  1D6H A;  2IB9 A;  1OX0 A;  4N44 A;  4EGV A;  4C73 A;  4O99 A;  4LS6 A;  3SQZ A;  4C71 A;  1ZOW A;  5HWO A;  2QO1 A;  2BZ3 A;  1CGZ A;  1D6F A;  5BYV A;  3HO2 A;  4JD3 A;  1HN9 A;  1HND A;  4OPE A;  1E5M A;  4JRH A;  4YXT A;  5F38 A;  3WD7 A;  5AB4 A;  2WL4 C;  4KU3 A;  5AB6 A;  3A5S A;  2GP6 A;  1QLV A;  2BUH A;  2BZ4 A;  4DFE A;  3H76 A;  1M4T A;  2WL5 C;  2UV8 A;  5BNR A;  2WKV A;  3IL9 A;  4XOX A;  2IIK A;  2IX4 A;  3HNZ A;  4O9C A;  2WGD A;  4C6W A;  3G0Y A;  4YXQ A;  1I86 A;  1HNK A;  4XS9 A;  2D3T C;  4C6Z A;  1ULQ A;  1DD8 A;  4OQJ A;  1HZP A;  2IWZ A;  5KP5 A;  4BIA A;  1JWX A;  2QO0 A;  5KP6 A;  2WGF A;  4KU2 A;  4X0O D;  3OIT A;  1YSL B;  1X9E A;  2WKT A;  2VZ8 A;  3LED A;  4Z8D A;  3I8P A;  1XPL A;  3EUQ A;  1WL5 A;  1F91 A;  3FK5 A;  4B0N A;  2C9H A;  3MQD A;  4V2P A;  4NA3 A;  4ZRC A;  4Z19 A;  2AQB A;  2GFY A;  3EUO A;  2F2S A;  4YLT A;  5F38 D;  2VU1 A;  1M1T A;  3T6S A;  1H4F A;  4O9A A;  2VB9 A;  3LEH A;  3GWA A;  1M4S A;  4W61 A;  1KAS A;  5KP8 A;  3T5Y B;  1TQY B;  2QNY A;  3ALE A; 
#chains in the Genus database with same CATH topology
 5HWQ A;  3ZBG A;  4JAR A;  4JRM A;  4JV3 A;  3IL6 A;  3S1Z A;  5BQS A;  1FJ4 A;  2F82 A;  2WL4 D;  2IB7 A;  4OPF A;  4QYR A;  1UB7 A;  5BZ4 A;  3IL3 A;  4C2J A;  3S20 A;  1WDK C;  3LRF A;  2QNX A;  5LOT A;  5E5N A;  1B3N A;  1EK4 A;  2GYO A;  2D52 A;  4KC5 A;  3U0E A;  1NL7 A;  3WXZ A;  4U4E A;  2BUI A;  2VTZ A;  1AFW A;  4UBU A;  2C7Z A;  5C1J A;  4NZS A;  3TSY A;  4LS5 A;  4DDO A;  4DD5 A;  3IL5 A;  1WDL C;  3OV3 A;  4C2K A;  5BNS A;  5HWR A;  4TKT A;  4B7V A;  3OV2 A;  2BYW A;  3ZBK A;  5AB5 A;  1PXT A;  4X9O A;  2WL4 A;  1TED A;  1XPK C;  3T6S B;  3WY0 A;  2VU0 A;  2WKU A;  3HHD A;  4B3H C;  4WUM A;  4UBW A;  2VBA A;  4B3J C;  1XES A;  1EBL A;  2VB7 C;  2FA0 A;  1CML A;  2WL5 A;  2IBU A;  2D3M A;  1OXH A;  3OYT A;  1EE0 A;  2BYZ A;  2X3E A;  4JAQ A;  2VB8 A;  1WL4 A;  3U0F A;  2P8U A;  3S3L A;  4XL3 A;  3T8E A;  1W0I A;  3IL7 A;  3E1H A;  4B3I C;  2WL6 A;  3S21 A;  2BYX A;  3EUT A;  1DLV A;  4YXV A;  4WYS A;  1G5X A;  4XL4 A;  5F38 B;  2IBW A;  2VU2 A;  2GQD A;  3AWK A;  2IBY A;  4LS7 A;  5CBQ A;  2IWY A;  4C6X A;  1J3N A;  4X9K A;  4XS7 A;  1FJ8 A;  1U0U A;  4ZDN A;  2D51 A;  3V4X A;  1XET A;  2VZ9 A;  4UBT A;  2GFW A;  1M1O A;  2WGG A;  1I8B A;  4WZU A;  1YSL A;  1U6E A;  3V4N A;  3E60 A;  4YZO A;  4F32 A;  1QFL A;  3A5Q A;  3H77 A;  5F38 C;  1MZS A;  1OU6 A;  5KP2 A;  4N45 A;  3SVK A;  2IB8 A;  3IL4 A;  2RJT A;  2QNZ A;  4LS8 A;  3GWE A;  3VS9 A;  4UBV A;  1U0W A;  4C70 A;  2P0U A;  3G11 A;  4EWG A;  3A5R A;  2EFT A;  4JAP A;  5AB7 A;  4XSB A;  3H78 A;  4NA1 A;  1DLU A;  1CGK A;  1WDM C;  1BQ6 A;  3ROW A;  2H84 A;  4R8E A;  4YUF A;  4WKY A;  3T5Y A;  1TQY A;  1M1M A;  2C7Y A;  5F0V A;  5LP7 A;  2BYY A;  4RYB A;  2FA3 A;  4JAO A;  5SXO A;  3WD8 A;  2WGE A;  1I89 A;  1TXT A;  4WYR A;  1M3Z A;  4NA2 A;  2WKT C;  1CHW A;  3GOA A;  3SS6 A;  4Z37 A;  5LNQ A;  5KP7 A;  2WUA A;  2AQ7 A;  4JAT A;  5TT4 A;  1HNJ A;  4C72 A;  2ALM A;  5LD8 A;  3KZU A;  4YJY A;  2AHB A;  2QX1 A;  4YUC A;  1D6I A;  1HNH A;  1Z1F A;  4E1L A;  5BNM A;  2WU9 A;  4KTI A;  5HWP A;  2EBD A;  3ZBN A;  1XPM A;  1XPK A;  1U6S A;  4XSA A;  4JPF A;  3WXY A;  4JGA A;  3VS8 A;  4C6U A;  2VB7 A;  1I88 A;  1Z1E A;  1DM3 A;  3ZBL A;  2F9A A;  1U0V A;  4C6V A;  1M3K A;  2GFX A;  3S23 A;  1TVZ A;  4XL2 A;  4JB6 A;  4NHD A;  4KTM A;  2HG4 A;  2GFV A;  1BI5 A;  1TEE A;  2AJ9 A;  1MZJ A;  1U0M A;  4EFI A;  5BY7 A;  2WYA A;  5DWZ C;  4KU5 A;  2HDB A;  3HO9 A;  3V7I A;  3AWJ A;  4X0O A;  4BI9 A;  2WL4 B;  2QO3 A;  3O04 A;  4EWP A;  4QAV A;  1D6H A;  2IB9 A;  1OX0 A;  4N44 A;  4EGV A;  4C73 A;  4O99 A;  4LS6 A;  3LMA A;  3SQZ A;  4C71 A;  1ZOW A;  5HWO A;  2QO1 A;  2BZ3 A;  1CGZ A;  1D6F A;  5BYV A;  3HO2 A;  4JD3 A;  1HN9 A;  1HND A;  4OPE A;  1E5M A;  4JRH A;  4YXT A;  5F38 A;  3WD7 A;  5AB4 A;  2WL4 C;  4KU3 A;  5AB6 A;  3A5S A;  2GP6 A;  1QLV A;  2BUH A;  2BZ4 A;  4DFE A;  3H76 A;  1M4T A;  2WL5 C;  2UV8 A;  5BNR A;  2WKV A;  3IL9 A;  4XOX A;  2IIK A;  2IX4 A;  3HNZ A;  4O9C A;  2WGD A;  4C6W A;  3G0Y A;  4YXQ A;  1I86 A;  1HNK A;  4XS9 A;  2D3T C;  4C6Z A;  1ULQ A;  1DD8 A;  4OQJ A;  1HZP A;  2IWZ A;  5KP5 A;  4BIA A;  1JWX A;  2QO0 A;  5KP6 A;  2WGF A;  4KU2 A;  4X0O D;  3OIT A;  1YSL B;  1X9E A;  2WKT A;  2VZ8 A;  3LED A;  4Z8D A;  3I8P A;  1XPL A;  3EUQ A;  1WL5 A;  1F91 A;  3FK5 A;  4B0N A;  2C9H A;  3MQD A;  4V2P A;  4NA3 A;  3LM6 A;  4ZRC A;  4Z19 A;  2AQB A;  2GFY A;  3EUO A;  2F2S A;  4YLT A;  5F38 D;  2VU1 A;  1M1T A;  3T6S A;  1H4F A;  4O9A A;  2VB9 A;  3LEH A;  3GWA A;  1M4S A;  4W61 A;  1KAS A;  5KP8 A;  3T5Y B;  1TQY B;  2QNY A;  3ALE A; 
#chains in the Genus database with same CATH homology
 5HWQ A;  3ZBG A;  4JAR A;  4JRM A;  4JV3 A;  3IL6 A;  3S1Z A;  5BQS A;  1FJ4 A;  2F82 A;  2WL4 D;  2IB7 A;  4OPF A;  4QYR A;  1UB7 A;  5BZ4 A;  3IL3 A;  4C2J A;  3S20 A;  1WDK C;  3LRF A;  2QNX A;  5LOT A;  5E5N A;  1B3N A;  1EK4 A;  2GYO A;  2D52 A;  4KC5 A;  3U0E A;  1NL7 A;  3WXZ A;  4U4E A;  2BUI A;  2VTZ A;  1AFW A;  4UBU A;  2C7Z A;  5C1J A;  4NZS A;  3TSY A;  4LS5 A;  4DDO A;  4DD5 A;  3IL5 A;  1WDL C;  3OV3 A;  4C2K A;  5BNS A;  5HWR A;  4TKT A;  4B7V A;  3OV2 A;  2BYW A;  3ZBK A;  5AB5 A;  1PXT A;  4X9O A;  2WL4 A;  1TED A;  1XPK C;  3T6S B;  3WY0 A;  2VU0 A;  2WKU A;  3HHD A;  4B3H C;  4WUM A;  4UBW A;  2VBA A;  4B3J C;  1XES A;  1EBL A;  2VB7 C;  2FA0 A;  1CML A;  2WL5 A;  2IBU A;  2D3M A;  1OXH A;  3OYT A;  1EE0 A;  2BYZ A;  2X3E A;  4JAQ A;  2VB8 A;  1WL4 A;  3U0F A;  2P8U A;  3S3L A;  4XL3 A;  3T8E A;  1W0I A;  3IL7 A;  3E1H A;  4B3I C;  2WL6 A;  3S21 A;  2BYX A;  3EUT A;  1DLV A;  4YXV A;  4WYS A;  1G5X A;  4XL4 A;  5F38 B;  2IBW A;  2VU2 A;  2GQD A;  3AWK A;  2IBY A;  4LS7 A;  5CBQ A;  2IWY A;  4C6X A;  1J3N A;  4X9K A;  4XS7 A;  1FJ8 A;  1U0U A;  4ZDN A;  2D51 A;  3V4X A;  1XET A;  2VZ9 A;  4UBT A;  2GFW A;  1M1O A;  2WGG A;  1I8B A;  4WZU A;  1YSL A;  1U6E A;  3V4N A;  3E60 A;  4YZO A;  4F32 A;  1QFL A;  3A5Q A;  3H77 A;  5F38 C;  1MZS A;  1OU6 A;  5KP2 A;  4N45 A;  3SVK A;  2IB8 A;  3IL4 A;  2RJT A;  2QNZ A;  4LS8 A;  3GWE A;  3VS9 A;  4UBV A;  1U0W A;  4C70 A;  2P0U A;  3G11 A;  4EWG A;  3A5R A;  2EFT A;  4JAP A;  5AB7 A;  4XSB A;  3H78 A;  4NA1 A;  1DLU A;  1CGK A;  1WDM C;  1BQ6 A;  3ROW A;  2H84 A;  4R8E A;  4YUF A;  4WKY A;  3T5Y A;  1TQY A;  1M1M A;  2C7Y A;  5F0V A;  5LP7 A;  2BYY A;  4RYB A;  2FA3 A;  4JAO A;  5SXO A;  3WD8 A;  2WGE A;  1I89 A;  1TXT A;  4WYR A;  1M3Z A;  4NA2 A;  2WKT C;  1CHW A;  3GOA A;  3SS6 A;  4Z37 A;  5LNQ A;  5KP7 A;  2WUA A;  2AQ7 A;  4JAT A;  5TT4 A;  1HNJ A;  4C72 A;  2ALM A;  5LD8 A;  3KZU A;  4YJY A;  2AHB A;  2QX1 A;  4YUC A;  1D6I A;  1HNH A;  1Z1F A;  4E1L A;  5BNM A;  2WU9 A;  4KTI A;  5HWP A;  2EBD A;  3ZBN A;  1XPM A;  1XPK A;  1U6S A;  4XSA A;  4JPF A;  3WXY A;  4JGA A;  3VS8 A;  4C6U A;  2VB7 A;  1I88 A;  1Z1E A;  1DM3 A;  3ZBL A;  2F9A A;  1U0V A;  4C6V A;  1M3K A;  2GFX A;  3S23 A;  1TVZ A;  4XL2 A;  4JB6 A;  4NHD A;  4KTM A;  2HG4 A;  2GFV A;  1BI5 A;  1TEE A;  2AJ9 A;  1MZJ A;  1U0M A;  4EFI A;  5BY7 A;  2WYA A;  5DWZ C;  4KU5 A;  2HDB A;  3HO9 A;  3V7I A;  3AWJ A;  4X0O A;  4BI9 A;  2WL4 B;  2QO3 A;  3O04 A;  4EWP A;  4QAV A;  1D6H A;  2IB9 A;  1OX0 A;  4N44 A;  4EGV A;  4C73 A;  4O99 A;  4LS6 A;  3LMA A;  3SQZ A;  4C71 A;  1ZOW A;  5HWO A;  2QO1 A;  2BZ3 A;  1CGZ A;  1D6F A;  5BYV A;  3HO2 A;  4JD3 A;  1HN9 A;  1HND A;  4OPE A;  1E5M A;  4JRH A;  4YXT A;  5F38 A;  3WD7 A;  5AB4 A;  2WL4 C;  4KU3 A;  5AB6 A;  3A5S A;  2GP6 A;  1QLV A;  2BUH A;  2BZ4 A;  4DFE A;  3H76 A;  1M4T A;  2WL5 C;  2UV8 A;  5BNR A;  2WKV A;  3IL9 A;  4XOX A;  2IIK A;  2IX4 A;  3HNZ A;  4O9C A;  2WGD A;  4C6W A;  3G0Y A;  4YXQ A;  1I86 A;  1HNK A;  4XS9 A;  2D3T C;  4C6Z A;  1ULQ A;  1DD8 A;  4OQJ A;  1HZP A;  2IWZ A;  5KP5 A;  4BIA A;  1JWX A;  2QO0 A;  5KP6 A;  2WGF A;  4KU2 A;  4X0O D;  3OIT A;  1YSL B;  1X9E A;  2WKT A;  2VZ8 A;  3LED A;  4Z8D A;  3I8P A;  1XPL A;  3EUQ A;  1WL5 A;  1F91 A;  3FK5 A;  4B0N A;  2C9H A;  3MQD A;  4V2P A;  4NA3 A;  3LM6 A;  4ZRC A;  4Z19 A;  2AQB A;  2GFY A;  3EUO A;  2F2S A;  4YLT A;  5F38 D;  2VU1 A;  1M1T A;  3T6S A;  1H4F A;  4O9A A;  2VB9 A;  3LEH A;  3GWA A;  1M4S A;  4W61 A;  1KAS A;  5KP8 A;  3T5Y B;  1TQY B;  2QNY A;  3ALE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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