3V4XA

The biochemical and structural basis for inhibition of enterococcus faecalis hmg-coa synthase, mvas, by hymeglusin
Total Genus 125
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
387
structure length
387
Chain Sequence
STGSMTIGIDKISFFVPPYYIDMTALAEARNVDPGKFHIGIGQDQMAVNPISQDIVTFAANAAEAILTKEDKEAIDMVIVGTESSIDESKAAAVVLHRLMGIQPFARSFEIKEACYGATAGLQLAKNHVALHPDKKVLVVAADIAKYGLNSGGEPTQGAGAVAMLVSSEPRILALKEDNVMLTQDIYDFWRPTGHPYPMVDGPLSNETYIQSFAQVWDEHKKRTGLDFADYDALAFHIPYTKMGKKALLAKISDQTEAEQERILARYEESIIYSRRVGNLYTGSLYLGLISLLENATTLTAGNQIGLFSYGSGAVAEFFTGELVAGYQNHLQKETHLALLDNRTELSIAEYEAMFAETLDTDIDQTLEDELKYSISAINNTVRSYRN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and structural basis for inhibition of Enterococcus faecalis hydroxymethylglutaryl-CoA synthase, mvaS, by hymeglusin.
pubmed doi rcsb
molecule tags Transferase/inhibitor
source organism Enterococcus faecalis
molecule keywords HMG-CoA synthase
total genus 125
structure length 387
sequence length 387
chains with identical sequence B, C, D
ec nomenclature ec 2.3.3.10: Hydroxymethylglutaryl-CoA synthase.
pdb deposition date 2011-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01154 HMG_CoA_synt_N Hydroxymethylglutaryl-coenzyme A synthase N terminal
A PF08540 HMG_CoA_synt_C Hydroxymethylglutaryl-coenzyme A synthase C terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.47.10 Alpha Beta 3-Layer(aba) Sandwich Peroxisomal Thiolase; Chain A, domain 1 Peroxisomal Thiolase; Chain A, domain 1 3v4xA01
3.40.47.10 Alpha Beta 3-Layer(aba) Sandwich Peroxisomal Thiolase; Chain A, domain 1 Peroxisomal Thiolase; Chain A, domain 1 3v4xA02
4WUMA 3ZBNA 5BQSA 2WL4C 1D6IA 1J3NA 4UBWA 4XOXA 3ROWA 4JRMA 3WXZA 1XESA 2IWYA 1XPKC 3V4XA 2AQ7A 4C71A 5LOTA 3VS8A 3S3LA 1I86A 3GWEA 3SQZA 2AHBA 5SXOA 3IL7A 1HNKA 4YJYA 4O99A 2HDBA 4YUFA 4DFEA 5HWOA 4KU3A 3LEDA 1WL5A 2P8UA 1QLVA 2BZ4A 5AB6A 3V4NA 5AB5A 3S23A 2WL5A 2EBDA 5F38A 4JARA 4YXQA 2IIKA 1ZOWA 5LD8A 3S21A 5F38D 2C7YA 4X0OA 5CBQA 1D6HA 4F32A 5LNQA 1CMLA 4X0OD 2IBYA 3VS9A 2GFWA 2WKTA 2VU1A 1M4SA 3G11A 1DM3A 3GWAA 4XSAA 3OITA 2F82A 2WGDA 3EUQA 3H76A 2QNXA 1I89A 4JGAA 5BNSA 2WL4A 4JAPA 2QO3A 1M1TA 4YLTA 2D51A 5F38C 1U0WA 4UBTA 1XPKA 4KTMA 1M4TA 4E1LA 3ZBLA 1XPLA 4W61A 2BYWA 4YXTA 1H4FA 1FJ8A 3KZUA 2QNZA 1WL4A 1CGKA 2GP6A 2WKTC 2H84A 1WDKC 4RYBA 3IL6A 4N44A 4B3HC 4KU2A 4C72A 1MZSA 1KASA 2FA3A 4OPFA 2VBAA 1I88A 4LS5A 4B3JC 4C6ZA 4QAVA 1M1MA 4KC5A 2VB9A 4XL4A 4V2PA 1U6EA 2GFXA 3A5SA 2IB8A 4JD3A 2VU2A 4XS7A 1DD8A 2BYZA 3E1HA 5BNMA 1BQ6A 5KP5A 2WGGA 3WD7A 4JPFA 1CGZA 2VU0A 1WDMC 1M1OA 1TQYB 3IL9A 3V7IA 2QNYA 5KP8A 2C9HA 2GFYA 4JB6A 5HWRA 1OX0A 4JATA 1UB7A 3H78A 3ZBGA 4U4EA 2D3MA 1FJ4A 4NA3A 2VZ8A 2IB7A 4OQJA 4C2KA 1WDLC 2BYXA 2IB9A 3S1ZA 1EBLA 2F2SA 4XS9A 1XPMA 3WD8A 4EWGA 4C6XA 2QO0A 3IL5A 3SS6A 4C73A 2VTZA 4B3IC 1Z1EA 5AB7A 1AFWA 4Z8DA 4O9CA 1TEDA 1YSLA 3U0EA 1X9EA 3T5YB 1B3NA 2UV8A 2WU9A 4C6UA 2D3TC 4JAQA 4UBUA 4C6VA 2BYYA 5F0VA 2AJ9A 3EUOA 2HG4A 1M3KA 4KTIA 4B0NA 4XL3A 1W0IA 5DWZC 4NA2A 2VB8A 1EK4A 2QO1A 4QYRA 2X3EA 2WYAA 3HHDA 3FK5A 3EUTA 1EE0A 5HWPA 3O04A 3IL4A 2FA0A 2VB7A 3WXYA 1TQYA 2AQBA 4BIAA 1JWXA 2WL4B 1E5MA 4BI9A 1OU6A 4WKYA 4YZOA 2P0UA 1DLUA 1HN9A 1F91A 1Z1FA 1OXHA 1U0UA 5BNRA 5BZ4A 3HO2A 1U0VA 2GQDA 4NHDA 1HNJA 3A5RA 2ALMA 3HNZA 4EWPA 1D6FA 1DLVA 1PXTA 2C7ZA 4TKTA 2WKVA 4Z19A 2IX4A 4WYRA 2WGFA 4C2JA 2IBUA 3T6SB 2VB7C 2IBWA 3OYTA 2WGEA 2WKUA 3A5QA 4JRHA 4EGVA 4XL2A 1M3ZA 3G0YA 4R8EA 1U6SA 1MZJA 4NA1A 5AB4A 3AWJA 3T5YA 4LS8A 4N45A 2IWZA 3HO9A 2BUIA 4DDOA 3GOAA 1TXTA 4XSBA 4C6WA 2EFTA 1I8BA 3OV3A 4B7VA 4O9AA 2BUHA 4NZSA 4YUCA 2D52A 1HNDA 5LP7A 4JAOA 5KP7A 4X9KA 3WY0A 4EFIA 3IL3A 1HNHA 5BYVA 2RJTA 1TVZA 4KU5A 1G5XA 3TSYA 3MQDA 5E5NA 5TT4A 4ZDNA 2WUAA 4DD5A 1ULQA 3H77A 3LEHA 5F38B 1QFLA 2VZ9A 1U0MA 4LS7A 3U0FA 3ALEA 4JV3A 5KP2A 2WL5C 1TEEA 3AWKA 4YXVA 4X9OA 4LS6A 1XETA 4ZRCA 2QX1A 2WL4D 2WL6A 4OPEA 1CHWA 2GYOA 3ZBKA 1BI5A 3S20A 4C70A 5C1JA 1NL7A 3SVKA 5BY7A 4Z37A 2F9AA 5KP6A 3LRFA 1HZPA 2BZ3A 4WZUA 1YSLB 4WYSA 3T8EA 3OV2A 5HWQA 3T6SA 3I8PA 3E60A 4UBVA 2GFVA
chains in the Genus database with same CATH superfamily
4WUMA 3ZBNA 5BQSA 2WL4C 1D6IA 1J3NA 4UBWA 4XOXA 3ROWA 4JRMA 3WXZA 1XESA 2IWYA 1XPKC 3V4XA 2AQ7A 4C71A 5LOTA 3VS8A 3S3LA 1I86A 3GWEA 3SQZA 2AHBA 5SXOA 3IL7A 1HNKA 4YJYA 4O99A 2HDBA 4YUFA 4DFEA 5HWOA 4KU3A 3LEDA 1WL5A 2P8UA 1QLVA 2BZ4A 5AB6A 3V4NA 5AB5A 3S23A 2WL5A 2EBDA 5F38A 4JARA 4YXQA 2IIKA 1ZOWA 5LD8A 3S21A 5F38D 2C7YA 4X0OA 5CBQA 1D6HA 4F32A 5LNQA 1CMLA 4X0OD 2IBYA 3VS9A 2GFWA 2WKTA 2VU1A 1M4SA 3G11A 1DM3A 3GWAA 4XSAA 3OITA 2F82A 2WGDA 3EUQA 3H76A 2QNXA 1I89A 4JGAA 5BNSA 2WL4A 4JAPA 2QO3A 1M1TA 4YLTA 2D51A 5F38C 1U0WA 4UBTA 1XPKA 4KTMA 1M4TA 4E1LA 3ZBLA 1XPLA 4W61A 2BYWA 3LMAA 4YXTA 1H4FA 1FJ8A 3KZUA 2QNZA 1WL4A 1CGKA 2GP6A 2WKTC 2H84A 1WDKC 4RYBA 3IL6A 4N44A 4B3HC 4KU2A 4C72A 1MZSA 1KASA 2FA3A 4OPFA 2VBAA 1I88A 4LS5A 4B3JC 4C6ZA 4QAVA 1M1MA 4KC5A 2VB9A 4XL4A 4V2PA 1U6EA 2GFXA 3A5SA 2IB8A 4JD3A 2VU2A 4XS7A 1DD8A 2BYZA 3E1HA 5BNMA 1BQ6A 5KP5A 2WGGA 3WD7A 4JPFA 1CGZA 2VU0A 1WDMC 1M1OA 1TQYB 3IL9A 3V7IA 2QNYA 5KP8A 2C9HA 2GFYA 4JB6A 5HWRA 1OX0A 4JATA 1UB7A 3H78A 3ZBGA 4U4EA 2D3MA 1FJ4A 4NA3A 2VZ8A 2IB7A 4OQJA 4C2KA 1WDLC 2BYXA 2IB9A 3S1ZA 1EBLA 2F2SA 4XS9A 1XPMA 3WD8A 4EWGA 4C6XA 2QO0A 3IL5A 3SS6A 4C73A 2VTZA 4B3IC 1Z1EA 5AB7A 1AFWA 4Z8DA 4O9CA 1TEDA 1YSLA 3U0EA 1X9EA 3T5YB 1B3NA 2UV8A 2WU9A 4C6UA 2D3TC 4JAQA 4UBUA 4C6VA 2BYYA 5F0VA 2AJ9A 3EUOA 2HG4A 1M3KA 4KTIA 4B0NA 4XL3A 1W0IA 5DWZC 4NA2A 2VB8A 1EK4A 2QO1A 4QYRA 2X3EA 2WYAA 3LM6A 3HHDA 3FK5A 3EUTA 1EE0A 5HWPA 3O04A 3IL4A 2FA0A 2VB7A 3WXYA 1TQYA 2AQBA 4BIAA 1JWXA 2WL4B 1E5MA 4BI9A 1OU6A 4WKYA 4YZOA 2P0UA 1DLUA 1HN9A 1F91A 1Z1FA 1OXHA 1U0UA 5BNRA 5BZ4A 3HO2A 1U0VA 2GQDA 4NHDA 1HNJA 3A5RA 2ALMA 3HNZA 4EWPA 1D6FA 1DLVA 1PXTA 2C7ZA 4TKTA 2WKVA 4Z19A 2IX4A 4WYRA 2WGFA 4C2JA 2IBUA 3T6SB 2VB7C 2IBWA 3OYTA 2WGEA 2WKUA 3A5QA 4JRHA 4EGVA 4XL2A 1M3ZA 3G0YA 4R8EA 1U6SA 1MZJA 4NA1A 5AB4A 3AWJA 3T5YA 4LS8A 4N45A 2IWZA 3HO9A 2BUIA 4DDOA 3GOAA 1TXTA 4XSBA 4C6WA 2EFTA 1I8BA 3OV3A 4B7VA 4O9AA 2BUHA 4NZSA 4YUCA 2D52A 1HNDA 5LP7A 4JAOA 5KP7A 4X9KA 3WY0A 4EFIA 3IL3A 1HNHA 5BYVA 2RJTA 1TVZA 4KU5A 1G5XA 3TSYA 3MQDA 5E5NA 5TT4A 4ZDNA 2WUAA 4DD5A 1ULQA 3H77A 3LEHA 5F38B 1QFLA 2VZ9A 1U0MA 4LS7A 3U0FA 3ALEA 4JV3A 5KP2A 2WL5C 1TEEA 3AWKA 4YXVA 4X9OA 4LS6A 1XETA 4ZRCA 2QX1A 2WL4D 2WL6A 4OPEA 1CHWA 2GYOA 3ZBKA 1BI5A 3S20A 4C70A 5C1JA 1NL7A 3SVKA 5BY7A 4Z37A 2F9AA 5KP6A 3LRFA 1HZPA 2BZ3A 4WZUA 1YSLB 4WYSA 3T8EA 3OV2A 5HWQA 3T6SA 3I8PA 3E60A 4UBVA 2GFVA
chains in the Genus database with same CATH topology
4WUMA 3ZBNA 5BQSA 2WL4C 1D6IA 1J3NA 4UBWA 4XOXA 3ROWA 4JRMA 3WXZA 1XESA 2IWYA 1XPKC 3V4XA 2AQ7A 4C71A 5LOTA 3VS8A 3S3LA 1I86A 3GWEA 3SQZA 2AHBA 5SXOA 3IL7A 1HNKA 4YJYA 4O99A 2HDBA 4YUFA 4DFEA 5HWOA 4KU3A 3LEDA 1WL5A 2P8UA 1QLVA 2BZ4A 5AB6A 3V4NA 5AB5A 3S23A 2WL5A 2EBDA 5F38A 4JARA 4YXQA 2IIKA 1ZOWA 5LD8A 3S21A 5F38D 2C7YA 4X0OA 5CBQA 1D6HA 4F32A 5LNQA 1CMLA 4X0OD 2IBYA 3VS9A 2GFWA 2WKTA 2VU1A 1M4SA 3G11A 1DM3A 3GWAA 4XSAA 3OITA 2F82A 2WGDA 3EUQA 3H76A 2QNXA 1I89A 4JGAA 5BNSA 2WL4A 4JAPA 2QO3A 1M1TA 4YLTA 2D51A 5F38C 1U0WA 4UBTA 1XPKA 4KTMA 1M4TA 4E1LA 3ZBLA 1XPLA 4W61A 2BYWA 3LMAA 4YXTA 1H4FA 1FJ8A 3KZUA 2QNZA 1WL4A 1CGKA 2GP6A 2WKTC 2H84A 1WDKC 4RYBA 3IL6A 4N44A 4B3HC 4KU2A 4C72A 1MZSA 1KASA 2FA3A 4OPFA 2VBAA 1I88A 4LS5A 4B3JC 4C6ZA 4QAVA 1M1MA 4KC5A 2VB9A 4XL4A 4V2PA 1U6EA 2GFXA 3A5SA 2IB8A 4JD3A 2VU2A 4XS7A 1DD8A 2BYZA 3E1HA 5BNMA 1BQ6A 5KP5A 2WGGA 3WD7A 4JPFA 1CGZA 2VU0A 1WDMC 1M1OA 1TQYB 3IL9A 3V7IA 2QNYA 5KP8A 2C9HA 2GFYA 4JB6A 5HWRA 1OX0A 4JATA 1UB7A 3H78A 3ZBGA 4U4EA 2D3MA 1FJ4A 4NA3A 2VZ8A 2IB7A 4OQJA 4C2KA 1WDLC 2BYXA 2IB9A 3S1ZA 1EBLA 2F2SA 4XS9A 1XPMA 3WD8A 4EWGA 4C6XA 2QO0A 3IL5A 3SS6A 4C73A 2VTZA 4B3IC 1Z1EA 5AB7A 1AFWA 4Z8DA 4O9CA 1TEDA 1YSLA 3U0EA 1X9EA 3T5YB 1B3NA 2UV8A 2WU9A 4C6UA 2D3TC 4JAQA 4UBUA 4C6VA 2BYYA 5F0VA 2AJ9A 3EUOA 2HG4A 1M3KA 4KTIA 4B0NA 4XL3A 1W0IA 5DWZC 4NA2A 2VB8A 1EK4A 2QO1A 4QYRA 2X3EA 2WYAA 3LM6A 3HHDA 3FK5A 3EUTA 1EE0A 5HWPA 3O04A 3IL4A 2FA0A 2VB7A 3WXYA 1TQYA 2AQBA 4BIAA 1JWXA 2WL4B 1E5MA 4BI9A 1OU6A 4WKYA 4YZOA 2P0UA 1DLUA 1HN9A 1F91A 1Z1FA 1OXHA 1U0UA 5BNRA 5BZ4A 3HO2A 1U0VA 2GQDA 4NHDA 1HNJA 3A5RA 2ALMA 3HNZA 4EWPA 1D6FA 1DLVA 1PXTA 2C7ZA 4TKTA 2WKVA 4Z19A 2IX4A 4WYRA 2WGFA 4C2JA 2IBUA 3T6SB 2VB7C 2IBWA 3OYTA 2WGEA 2WKUA 3A5QA 4JRHA 4EGVA 4XL2A 1M3ZA 3G0YA 4R8EA 1U6SA 1MZJA 4NA1A 5AB4A 3AWJA 3T5YA 4LS8A 4N45A 2IWZA 3HO9A 2BUIA 4DDOA 3GOAA 1TXTA 4XSBA 4C6WA 2EFTA 1I8BA 3OV3A 4B7VA 4O9AA 2BUHA 4NZSA 4YUCA 2D52A 1HNDA 5LP7A 4JAOA 5KP7A 4X9KA 3WY0A 4EFIA 3IL3A 1HNHA 5BYVA 2RJTA 1TVZA 4KU5A 1G5XA 3TSYA 3MQDA 5E5NA 5TT4A 4ZDNA 2WUAA 4DD5A 1ULQA 3H77A 3LEHA 5F38B 1QFLA 2VZ9A 1U0MA 4LS7A 3U0FA 3ALEA 4JV3A 5KP2A 2WL5C 1TEEA 3AWKA 4YXVA 4X9OA 4LS6A 1XETA 4ZRCA 2QX1A 2WL4D 2WL6A 4OPEA 1CHWA 2GYOA 3ZBKA 1BI5A 3S20A 4C70A 5C1JA 1NL7A 3SVKA 5BY7A 4Z37A 2F9AA 5KP6A 3LRFA 1HZPA 2BZ3A 4WZUA 1YSLB 4WYSA 3T8EA 3OV2A 5HWQA 3T6SA 3I8PA 3E60A 4UBVA 2GFVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WUM A;  3ZBN A;  5BQS A;  2WL4 C;  1D6I A;  1J3N A;  4UBW A;  4XOX A;  3ROW A;  4JRM A;  3WXZ A;  1XES A;  2IWY A;  1XPK C;  3V4X A;  2AQ7 A;  4C71 A;  5LOT A;  3VS8 A;  3S3L A;  1I86 A;  3GWE A;  3SQZ A;  2AHB A;  5SXO A;  3IL7 A;  1HNK A;  4YJY A;  4O99 A;  2HDB A;  4YUF A;  4DFE A;  5HWO A;  4KU3 A;  3LED A;  1WL5 A;  2P8U A;  1QLV A;  2BZ4 A;  5AB6 A;  3V4N A;  5AB5 A;  3S23 A;  2WL5 A;  2EBD A;  5F38 A;  4JAR A;  4YXQ A;  2IIK A;  1ZOW A;  5LD8 A;  3S21 A;  5F38 D;  2C7Y A;  4X0O A;  5CBQ A;  1D6H A;  4F32 A;  5LNQ A;  1CML A;  4X0O D;  2IBY A;  3VS9 A;  2GFW A;  2WKT A;  2VU1 A;  1M4S A;  3G11 A;  1DM3 A;  3GWA A;  4XSA A;  3OIT A;  2F82 A;  2WGD A;  3EUQ A;  3H76 A;  2QNX A;  1I89 A;  4JGA A;  5BNS A;  2WL4 A;  4JAP A;  2QO3 A;  1M1T A;  4YLT A;  2D51 A;  5F38 C;  1U0W A;  4UBT A;  1XPK A;  4KTM A;  1M4T A;  4E1L A;  3ZBL A;  1XPL A;  4W61 A;  2BYW A;  4YXT A;  1H4F A;  1FJ8 A;  3KZU A;  2QNZ A;  1WL4 A;  1CGK A;  2GP6 A;  2WKT C;  2H84 A;  1WDK C;  4RYB A;  3IL6 A;  4N44 A;  4B3H C;  4KU2 A;  4C72 A;  1MZS A;  1KAS A;  2FA3 A;  4OPF A;  2VBA A;  1I88 A;  4LS5 A;  4B3J C;  4C6Z A;  4QAV A;  1M1M A;  4KC5 A;  2VB9 A;  4XL4 A;  4V2P A;  1U6E A;  2GFX A;  3A5S A;  2IB8 A;  4JD3 A;  2VU2 A;  4XS7 A;  1DD8 A;  2BYZ A;  3E1H A;  5BNM A;  1BQ6 A;  5KP5 A;  2WGG A;  3WD7 A;  4JPF A;  1CGZ A;  2VU0 A;  1WDM C;  1M1O A;  1TQY B;  3IL9 A;  3V7I A;  2QNY A;  5KP8 A;  2C9H A;  2GFY A;  4JB6 A;  5HWR A;  1OX0 A;  4JAT A;  1UB7 A;  3H78 A;  3ZBG A;  4U4E A;  2D3M A;  1FJ4 A;  4NA3 A;  2VZ8 A;  2IB7 A;  4OQJ A;  4C2K A;  1WDL C;  2BYX A;  2IB9 A;  3S1Z A;  1EBL A;  2F2S A;  4XS9 A;  1XPM A;  3WD8 A;  4EWG A;  4C6X A;  2QO0 A;  3IL5 A;  3SS6 A;  4C73 A;  2VTZ A;  4B3I C;  1Z1E A;  5AB7 A;  1AFW A;  4Z8D A;  4O9C A;  1TED A;  1YSL A;  3U0E A;  1X9E A;  3T5Y B;  1B3N A;  2UV8 A;  2WU9 A;  4C6U A;  2D3T C;  4JAQ A;  4UBU A;  4C6V A;  2BYY A;  5F0V A;  2AJ9 A;  3EUO A;  2HG4 A;  1M3K A;  4KTI A;  4B0N A;  4XL3 A;  1W0I A;  5DWZ C;  4NA2 A;  2VB8 A;  1EK4 A;  2QO1 A;  4QYR A;  2X3E A;  2WYA A;  3HHD A;  3FK5 A;  3EUT A;  1EE0 A;  5HWP A;  3O04 A;  3IL4 A;  2FA0 A;  2VB7 A;  3WXY A;  1TQY A;  2AQB A;  4BIA A;  1JWX A;  2WL4 B;  1E5M A;  4BI9 A;  1OU6 A;  4WKY A;  4YZO A;  2P0U A;  1DLU A;  1HN9 A;  1F91 A;  1Z1F A;  1OXH A;  1U0U A;  5BNR A;  5BZ4 A;  3HO2 A;  1U0V A;  2GQD A;  4NHD A;  1HNJ A;  3A5R A;  2ALM A;  3HNZ A;  4EWP A;  1D6F A;  1DLV A;  1PXT A;  2C7Z A;  4TKT A;  2WKV A;  4Z19 A;  2IX4 A;  4WYR A;  2WGF A;  4C2J A;  2IBU A;  3T6S B;  2VB7 C;  2IBW A;  3OYT A;  2WGE A;  2WKU A;  3A5Q A;  4JRH A;  4EGV A;  4XL2 A;  1M3Z A;  3G0Y A;  4R8E A;  1U6S A;  1MZJ A;  4NA1 A;  5AB4 A;  3AWJ A;  3T5Y A;  4LS8 A;  4N45 A;  2IWZ A;  3HO9 A;  2BUI A;  4DDO A;  3GOA A;  1TXT A;  4XSB A;  4C6W A;  2EFT A;  1I8B A;  3OV3 A;  4B7V A;  4O9A A;  2BUH A;  4NZS A;  4YUC A;  2D52 A;  1HND A;  5LP7 A;  4JAO A;  5KP7 A;  4X9K A;  3WY0 A;  4EFI A;  3IL3 A;  1HNH A;  5BYV A;  2RJT A;  1TVZ A;  4KU5 A;  1G5X A;  3TSY A;  3MQD A;  5E5N A;  5TT4 A;  4ZDN A;  2WUA A;  4DD5 A;  1ULQ A;  3H77 A;  3LEH A;  5F38 B;  1QFL A;  2VZ9 A;  1U0M A;  4LS7 A;  3U0F A;  3ALE A;  4JV3 A;  5KP2 A;  2WL5 C;  1TEE A;  3AWK A;  4YXV A;  4X9O A;  4LS6 A;  1XET A;  4ZRC A;  2QX1 A;  2WL4 D;  2WL6 A;  4OPE A;  1CHW A;  2GYO A;  3ZBK A;  1BI5 A;  3S20 A;  4C70 A;  5C1J A;  1NL7 A;  3SVK A;  5BY7 A;  4Z37 A;  2F9A A;  5KP6 A;  3LRF A;  1HZP A;  2BZ3 A;  4WZU A;  1YSL B;  4WYS A;  3T8E A;  3OV2 A;  5HWQ A;  3T6S A;  3I8P A;  3E60 A;  4UBV A;  2GFV A; 
#chains in the Genus database with same CATH topology
 4WUM A;  3ZBN A;  5BQS A;  2WL4 C;  1D6I A;  1J3N A;  4UBW A;  4XOX A;  3ROW A;  4JRM A;  3WXZ A;  1XES A;  2IWY A;  1XPK C;  3V4X A;  2AQ7 A;  4C71 A;  5LOT A;  3VS8 A;  3S3L A;  1I86 A;  3GWE A;  3SQZ A;  2AHB A;  5SXO A;  3IL7 A;  1HNK A;  4YJY A;  4O99 A;  2HDB A;  4YUF A;  4DFE A;  5HWO A;  4KU3 A;  3LED A;  1WL5 A;  2P8U A;  1QLV A;  2BZ4 A;  5AB6 A;  3V4N A;  5AB5 A;  3S23 A;  2WL5 A;  2EBD A;  5F38 A;  4JAR A;  4YXQ A;  2IIK A;  1ZOW A;  5LD8 A;  3S21 A;  5F38 D;  2C7Y A;  4X0O A;  5CBQ A;  1D6H A;  4F32 A;  5LNQ A;  1CML A;  4X0O D;  2IBY A;  3VS9 A;  2GFW A;  2WKT A;  2VU1 A;  1M4S A;  3G11 A;  1DM3 A;  3GWA A;  4XSA A;  3OIT A;  2F82 A;  2WGD A;  3EUQ A;  3H76 A;  2QNX A;  1I89 A;  4JGA A;  5BNS A;  2WL4 A;  4JAP A;  2QO3 A;  1M1T A;  4YLT A;  2D51 A;  5F38 C;  1U0W A;  4UBT A;  1XPK A;  4KTM A;  1M4T A;  4E1L A;  3ZBL A;  1XPL A;  4W61 A;  2BYW A;  3LMA A;  4YXT A;  1H4F A;  1FJ8 A;  3KZU A;  2QNZ A;  1WL4 A;  1CGK A;  2GP6 A;  2WKT C;  2H84 A;  1WDK C;  4RYB A;  3IL6 A;  4N44 A;  4B3H C;  4KU2 A;  4C72 A;  1MZS A;  1KAS A;  2FA3 A;  4OPF A;  2VBA A;  1I88 A;  4LS5 A;  4B3J C;  4C6Z A;  4QAV A;  1M1M A;  4KC5 A;  2VB9 A;  4XL4 A;  4V2P A;  1U6E A;  2GFX A;  3A5S A;  2IB8 A;  4JD3 A;  2VU2 A;  4XS7 A;  1DD8 A;  2BYZ A;  3E1H A;  5BNM A;  1BQ6 A;  5KP5 A;  2WGG A;  3WD7 A;  4JPF A;  1CGZ A;  2VU0 A;  1WDM C;  1M1O A;  1TQY B;  3IL9 A;  3V7I A;  2QNY A;  5KP8 A;  2C9H A;  2GFY A;  4JB6 A;  5HWR A;  1OX0 A;  4JAT A;  1UB7 A;  3H78 A;  3ZBG A;  4U4E A;  2D3M A;  1FJ4 A;  4NA3 A;  2VZ8 A;  2IB7 A;  4OQJ A;  4C2K A;  1WDL C;  2BYX A;  2IB9 A;  3S1Z A;  1EBL A;  2F2S A;  4XS9 A;  1XPM A;  3WD8 A;  4EWG A;  4C6X A;  2QO0 A;  3IL5 A;  3SS6 A;  4C73 A;  2VTZ A;  4B3I C;  1Z1E A;  5AB7 A;  1AFW A;  4Z8D A;  4O9C A;  1TED A;  1YSL A;  3U0E A;  1X9E A;  3T5Y B;  1B3N A;  2UV8 A;  2WU9 A;  4C6U A;  2D3T C;  4JAQ A;  4UBU A;  4C6V A;  2BYY A;  5F0V A;  2AJ9 A;  3EUO A;  2HG4 A;  1M3K A;  4KTI A;  4B0N A;  4XL3 A;  1W0I A;  5DWZ C;  4NA2 A;  2VB8 A;  1EK4 A;  2QO1 A;  4QYR A;  2X3E A;  2WYA A;  3LM6 A;  3HHD A;  3FK5 A;  3EUT A;  1EE0 A;  5HWP A;  3O04 A;  3IL4 A;  2FA0 A;  2VB7 A;  3WXY A;  1TQY A;  2AQB A;  4BIA A;  1JWX A;  2WL4 B;  1E5M A;  4BI9 A;  1OU6 A;  4WKY A;  4YZO A;  2P0U A;  1DLU A;  1HN9 A;  1F91 A;  1Z1F A;  1OXH A;  1U0U A;  5BNR A;  5BZ4 A;  3HO2 A;  1U0V A;  2GQD A;  4NHD A;  1HNJ A;  3A5R A;  2ALM A;  3HNZ A;  4EWP A;  1D6F A;  1DLV A;  1PXT A;  2C7Z A;  4TKT A;  2WKV A;  4Z19 A;  2IX4 A;  4WYR A;  2WGF A;  4C2J A;  2IBU A;  3T6S B;  2VB7 C;  2IBW A;  3OYT A;  2WGE A;  2WKU A;  3A5Q A;  4JRH A;  4EGV A;  4XL2 A;  1M3Z A;  3G0Y A;  4R8E A;  1U6S A;  1MZJ A;  4NA1 A;  5AB4 A;  3AWJ A;  3T5Y A;  4LS8 A;  4N45 A;  2IWZ A;  3HO9 A;  2BUI A;  4DDO A;  3GOA A;  1TXT A;  4XSB A;  4C6W A;  2EFT A;  1I8B A;  3OV3 A;  4B7V A;  4O9A A;  2BUH A;  4NZS A;  4YUC A;  2D52 A;  1HND A;  5LP7 A;  4JAO A;  5KP7 A;  4X9K A;  3WY0 A;  4EFI A;  3IL3 A;  1HNH A;  5BYV A;  2RJT A;  1TVZ A;  4KU5 A;  1G5X A;  3TSY A;  3MQD A;  5E5N A;  5TT4 A;  4ZDN A;  2WUA A;  4DD5 A;  1ULQ A;  3H77 A;  3LEH A;  5F38 B;  1QFL A;  2VZ9 A;  1U0M A;  4LS7 A;  3U0F A;  3ALE A;  4JV3 A;  5KP2 A;  2WL5 C;  1TEE A;  3AWK A;  4YXV A;  4X9O A;  4LS6 A;  1XET A;  4ZRC A;  2QX1 A;  2WL4 D;  2WL6 A;  4OPE A;  1CHW A;  2GYO A;  3ZBK A;  1BI5 A;  3S20 A;  4C70 A;  5C1J A;  1NL7 A;  3SVK A;  5BY7 A;  4Z37 A;  2F9A A;  5KP6 A;  3LRF A;  1HZP A;  2BZ3 A;  4WZU A;  1YSL B;  4WYS A;  3T8E A;  3OV2 A;  5HWQ A;  3T6S A;  3I8P A;  3E60 A;  4UBV A;  2GFV A; 
#chains in the Genus database with same CATH homology
 4WUM A;  3ZBN A;  5BQS A;  2WL4 C;  1D6I A;  1J3N A;  4UBW A;  4XOX A;  3ROW A;  4JRM A;  3WXZ A;  1XES A;  2IWY A;  1XPK C;  3V4X A;  2AQ7 A;  4C71 A;  5LOT A;  3VS8 A;  3S3L A;  1I86 A;  3GWE A;  3SQZ A;  2AHB A;  5SXO A;  3IL7 A;  1HNK A;  4YJY A;  4O99 A;  2HDB A;  4YUF A;  4DFE A;  5HWO A;  4KU3 A;  3LED A;  1WL5 A;  2P8U A;  1QLV A;  2BZ4 A;  5AB6 A;  3V4N A;  5AB5 A;  3S23 A;  2WL5 A;  2EBD A;  5F38 A;  4JAR A;  4YXQ A;  2IIK A;  1ZOW A;  5LD8 A;  3S21 A;  5F38 D;  2C7Y A;  4X0O A;  5CBQ A;  1D6H A;  4F32 A;  5LNQ A;  1CML A;  4X0O D;  2IBY A;  3VS9 A;  2GFW A;  2WKT A;  2VU1 A;  1M4S A;  3G11 A;  1DM3 A;  3GWA A;  4XSA A;  3OIT A;  2F82 A;  2WGD A;  3EUQ A;  3H76 A;  2QNX A;  1I89 A;  4JGA A;  5BNS A;  2WL4 A;  4JAP A;  2QO3 A;  1M1T A;  4YLT A;  2D51 A;  5F38 C;  1U0W A;  4UBT A;  1XPK A;  4KTM A;  1M4T A;  4E1L A;  3ZBL A;  1XPL A;  4W61 A;  2BYW A;  3LMA A;  4YXT A;  1H4F A;  1FJ8 A;  3KZU A;  2QNZ A;  1WL4 A;  1CGK A;  2GP6 A;  2WKT C;  2H84 A;  1WDK C;  4RYB A;  3IL6 A;  4N44 A;  4B3H C;  4KU2 A;  4C72 A;  1MZS A;  1KAS A;  2FA3 A;  4OPF A;  2VBA A;  1I88 A;  4LS5 A;  4B3J C;  4C6Z A;  4QAV A;  1M1M A;  4KC5 A;  2VB9 A;  4XL4 A;  4V2P A;  1U6E A;  2GFX A;  3A5S A;  2IB8 A;  4JD3 A;  2VU2 A;  4XS7 A;  1DD8 A;  2BYZ A;  3E1H A;  5BNM A;  1BQ6 A;  5KP5 A;  2WGG A;  3WD7 A;  4JPF A;  1CGZ A;  2VU0 A;  1WDM C;  1M1O A;  1TQY B;  3IL9 A;  3V7I A;  2QNY A;  5KP8 A;  2C9H A;  2GFY A;  4JB6 A;  5HWR A;  1OX0 A;  4JAT A;  1UB7 A;  3H78 A;  3ZBG A;  4U4E A;  2D3M A;  1FJ4 A;  4NA3 A;  2VZ8 A;  2IB7 A;  4OQJ A;  4C2K A;  1WDL C;  2BYX A;  2IB9 A;  3S1Z A;  1EBL A;  2F2S A;  4XS9 A;  1XPM A;  3WD8 A;  4EWG A;  4C6X A;  2QO0 A;  3IL5 A;  3SS6 A;  4C73 A;  2VTZ A;  4B3I C;  1Z1E A;  5AB7 A;  1AFW A;  4Z8D A;  4O9C A;  1TED A;  1YSL A;  3U0E A;  1X9E A;  3T5Y B;  1B3N A;  2UV8 A;  2WU9 A;  4C6U A;  2D3T C;  4JAQ A;  4UBU A;  4C6V A;  2BYY A;  5F0V A;  2AJ9 A;  3EUO A;  2HG4 A;  1M3K A;  4KTI A;  4B0N A;  4XL3 A;  1W0I A;  5DWZ C;  4NA2 A;  2VB8 A;  1EK4 A;  2QO1 A;  4QYR A;  2X3E A;  2WYA A;  3LM6 A;  3HHD A;  3FK5 A;  3EUT A;  1EE0 A;  5HWP A;  3O04 A;  3IL4 A;  2FA0 A;  2VB7 A;  3WXY A;  1TQY A;  2AQB A;  4BIA A;  1JWX A;  2WL4 B;  1E5M A;  4BI9 A;  1OU6 A;  4WKY A;  4YZO A;  2P0U A;  1DLU A;  1HN9 A;  1F91 A;  1Z1F A;  1OXH A;  1U0U A;  5BNR A;  5BZ4 A;  3HO2 A;  1U0V A;  2GQD A;  4NHD A;  1HNJ A;  3A5R A;  2ALM A;  3HNZ A;  4EWP A;  1D6F A;  1DLV A;  1PXT A;  2C7Z A;  4TKT A;  2WKV A;  4Z19 A;  2IX4 A;  4WYR A;  2WGF A;  4C2J A;  2IBU A;  3T6S B;  2VB7 C;  2IBW A;  3OYT A;  2WGE A;  2WKU A;  3A5Q A;  4JRH A;  4EGV A;  4XL2 A;  1M3Z A;  3G0Y A;  4R8E A;  1U6S A;  1MZJ A;  4NA1 A;  5AB4 A;  3AWJ A;  3T5Y A;  4LS8 A;  4N45 A;  2IWZ A;  3HO9 A;  2BUI A;  4DDO A;  3GOA A;  1TXT A;  4XSB A;  4C6W A;  2EFT A;  1I8B A;  3OV3 A;  4B7V A;  4O9A A;  2BUH A;  4NZS A;  4YUC A;  2D52 A;  1HND A;  5LP7 A;  4JAO A;  5KP7 A;  4X9K A;  3WY0 A;  4EFI A;  3IL3 A;  1HNH A;  5BYV A;  2RJT A;  1TVZ A;  4KU5 A;  1G5X A;  3TSY A;  3MQD A;  5E5N A;  5TT4 A;  4ZDN A;  2WUA A;  4DD5 A;  1ULQ A;  3H77 A;  3LEH A;  5F38 B;  1QFL A;  2VZ9 A;  1U0M A;  4LS7 A;  3U0F A;  3ALE A;  4JV3 A;  5KP2 A;  2WL5 C;  1TEE A;  3AWK A;  4YXV A;  4X9O A;  4LS6 A;  1XET A;  4ZRC A;  2QX1 A;  2WL4 D;  2WL6 A;  4OPE A;  1CHW A;  2GYO A;  3ZBK A;  1BI5 A;  3S20 A;  4C70 A;  5C1J A;  1NL7 A;  3SVK A;  5BY7 A;  4Z37 A;  2F9A A;  5KP6 A;  3LRF A;  1HZP A;  2BZ3 A;  4WZU A;  1YSL B;  4WYS A;  3T8E A;  3OV2 A;  5HWQ A;  3T6S A;  3I8P A;  3E60 A;  4UBV A;  2GFV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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