2FF1A

Crystal structure of trypanosoma vivax nucleoside hydrolase soaked with immucillinh
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
327
structure length
314
Chain Sequence
SAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
pubmed doi rcsb
molecule keywords IAG-nucleoside hydrolase
molecule tags Hydrolase
source organism Trypanosoma vivax
total genus 112
structure length 314
sequence length 327
chains with identical sequence B
ec nomenclature ec 3.2.2.1: Purine nucleosidase.
pdb deposition date 2005-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 2ff1A00
3MKMA 1Q8FA 4KL0A 2FF2A 1MASA 3EPWA 3T8IA 3EPXA 1EZRA 4I70A 3G5IA 4WR2A 4I72A 1HOZA 2YHGA 1HP0A 1R4FA 3FZ0A 1KIEA 4KPNA 1YOEA 2MASA 4I74A 2FF1A 4P5FA 3B9GA 5TSQA 3MKNA 2C40A 4I75A 3T8JA 4I71A 1KICA 3B9XA 4KPOA 4I73A
chains in the Genus database with same CATH superfamily
3MKMA 1Q8FA 4KL0A 2FF2A 1MASA 3EPWA 3T8IA 3EPXA 1EZRA 4I70A 3G5IA 4WR2A 4I72A 1HOZA 2YHGA 1HP0A 1R4FA 3FZ0A 1KIEA 4KPNA 1YOEA 2MASA 4I74A 2FF1A 4P5FA 3B9GA 5TSQA 3MKNA 2C40A 4I75A 3T8JA 4I71A 1KICA 3B9XA 4KPOA 4I73A
chains in the Genus database with same CATH topology
3MKMA 1Q8FA 4KL0A 2FF2A 1MASA 3EPWA 3T8IA 3EPXA 1EZRA 4I70A 3G5IA 4WR2A 4I72A 1HOZA 2YHGA 1HP0A 1R4FA 3FZ0A 1KIEA 4KPNA 1YOEA 2MASA 4I74A 2FF1A 4P5FA 3B9GA 5TSQA 3MKNA 2C40A 4I75A 3T8JA 4I71A 1KICA 3B9XA 4KPOA 4I73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MKM A;  1Q8F A;  4KL0 A;  2FF2 A;  1MAS A;  3EPW A;  3T8I A;  3EPX A;  1EZR A;  4I70 A;  3G5I A;  4WR2 A;  4I72 A;  1HOZ A;  2YHG A;  1HP0 A;  1R4F A;  3FZ0 A;  1KIE A;  4KPN A;  1YOE A;  2MAS A;  4I74 A;  2FF1 A;  4P5F A;  3B9G A;  5TSQ A;  3MKN A;  2C40 A;  4I75 A;  3T8J A;  4I71 A;  1KIC A;  3B9X A;  4KPO A;  4I73 A; 
#chains in the Genus database with same CATH topology
 3MKM A;  1Q8F A;  4KL0 A;  2FF2 A;  1MAS A;  3EPW A;  3T8I A;  3EPX A;  1EZR A;  4I70 A;  3G5I A;  4WR2 A;  4I72 A;  1HOZ A;  2YHG A;  1HP0 A;  1R4F A;  3FZ0 A;  1KIE A;  4KPN A;  1YOE A;  2MAS A;  4I74 A;  2FF1 A;  4P5F A;  3B9G A;  5TSQ A;  3MKN A;  2C40 A;  4I75 A;  3T8J A;  4I71 A;  1KIC A;  3B9X A;  4KPO A;  4I73 A; 
#chains in the Genus database with same CATH homology
 3MKM A;  1Q8F A;  4KL0 A;  2FF2 A;  1MAS A;  3EPW A;  3T8I A;  3EPX A;  1EZR A;  4I70 A;  3G5I A;  4WR2 A;  4I72 A;  1HOZ A;  2YHG A;  1HP0 A;  1R4F A;  3FZ0 A;  1KIE A;  4KPN A;  1YOE A;  2MAS A;  4I74 A;  2FF1 A;  4P5F A;  3B9G A;  5TSQ A;  3MKN A;  2C40 A;  4I75 A;  3T8J A;  4I71 A;  1KIC A;  3B9X A;  4KPO A;  4I73 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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