2FF1 | Genus

Total Genus 112

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	112
sequence length	327
structure length	314
Chain Sequence	SAKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 314 atoms

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314 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis. pubmed doi rcsb
molecule keywords	IAG-nucleoside hydrolase
molecule tags	Hydrolase
source organism	Trypanosoma vivax
total genus	112
structure length	314
sequence length	327
chains with identical sequence	B
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2005-12-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	2ff1A00

3T8JA 3B9GA 3EPXA 1Q8FA 2YHGA 2FF2A 3MKMA 2MASA 1EZRA 3T8IA 1MASA 2FF1A 4I74A 4KPOA 3MKNA 4P5FA 5TSQA 2C40A 1R4FA 1KIEA 1YOEA 4KL0A 4I73A 3G5IA 1HOZA 3B9XA 4KPNA 1HP0A 3EPWA 3FZ0A 4I71A 1KICA 4I70A 4I75A 4WR2A 4I72A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3T8J A;  3B9G A;  3EPX A;  1Q8F A;  2YHG A;  2FF2 A;  3MKM A;  2MAS A;  1EZR A;  3T8I A;  1MAS A;  2FF1 A;  4I74 A;  4KPO A;  3MKN A;  4P5F A;  5TSQ A;  2C40 A;  1R4F A;  1KIE A;  1YOE A;  4KL0 A;  4I73 A;  3G5I A;  1HOZ A;  3B9X A;  4KPN A;  1HP0 A;  3EPW A;  3FZ0 A;  4I71 A;  1KIC A;  4I70 A;  4I75 A;  4WR2 A;  4I72 A; 
#chains in the Genus database with same CATH topology
 3T8J A;  3B9G A;  3EPX A;  1Q8F A;  2YHG A;  2FF2 A;  3MKM A;  2MAS A;  1EZR A;  3T8I A;  1MAS A;  2FF1 A;  4I74 A;  4KPO A;  3MKN A;  4P5F A;  5TSQ A;  2C40 A;  1R4F A;  1KIE A;  1YOE A;  4KL0 A;  4I73 A;  3G5I A;  1HOZ A;  3B9X A;  4KPN A;  1HP0 A;  3EPW A;  3FZ0 A;  4I71 A;  1KIC A;  4I70 A;  4I75 A;  4WR2 A;  4I72 A; 
#chains in the Genus database with same CATH homology
 3T8J A;  3B9G A;  3EPX A;  1Q8F A;  2YHG A;  2FF2 A;  3MKM A;  2MAS A;  1EZR A;  3T8I A;  1MAS A;  2FF1 A;  4I74 A;  4KPO A;  3MKN A;  4P5F A;  5TSQ A;  2C40 A;  1R4F A;  1KIE A;  1YOE A;  4KL0 A;  4I73 A;  3G5I A;  1HOZ A;  3B9X A;  4KPN A;  1HP0 A;  3EPW A;  3FZ0 A;  4I71 A;  1KIC A;  4I70 A;  4I75 A;  4WR2 A;  4I72 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2FF1A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations