2FF2A

Crystal structure of trypanosoma vivax nucleoside hydrolase co-crystallized with immucillinh
Total Genus 122
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
326
structure length
326
Chain Sequence
AKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCELLRDGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma vivax
molecule keywords IAG-nucleoside hydrolase
total genus 122
structure length 326
sequence length 326
chains with identical sequence B
ec nomenclature ec 3.2.2.1: Purine nucleosidase.
pdb deposition date 2005-12-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 2ff2A00
1HP0A 4WR2A 1HOZA 2FF2A 3FZ0A 1R4FA 3MKNA 4I73A 5TSQA 1Q8FA 1KIEA 2MASA 3B9GA 1YOEA 4I74A 4KPOA 3T8IA 1KICA 2C40A 4I71A 2YHGA 3MKMA 3EPWA 3B9XA 4P5FA 4KPNA 3G5IA 3EPXA 4KL0A 1EZRA 4I72A 1MASA 2FF1A 3T8JA 4I75A 4I70A
chains in the Genus database with same CATH superfamily
1HP0A 4WR2A 1HOZA 2FF2A 3FZ0A 1R4FA 3MKNA 4I73A 5TSQA 1Q8FA 1KIEA 2MASA 3B9GA 1YOEA 4I74A 4KPOA 3T8IA 1KICA 2C40A 4I71A 2YHGA 3MKMA 3EPWA 3B9XA 4P5FA 4KPNA 3G5IA 3EPXA 4KL0A 1EZRA 4I72A 1MASA 2FF1A 3T8JA 4I75A 4I70A
chains in the Genus database with same CATH topology
1HP0A 4WR2A 1HOZA 2FF2A 3FZ0A 1R4FA 3MKNA 4I73A 5TSQA 1Q8FA 1KIEA 2MASA 3B9GA 1YOEA 4I74A 4KPOA 3T8IA 1KICA 2C40A 4I71A 2YHGA 3MKMA 3EPWA 3B9XA 4P5FA 4KPNA 3G5IA 3EPXA 4KL0A 1EZRA 4I72A 1MASA 2FF1A 3T8JA 4I75A 4I70A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HP0 A;  4WR2 A;  1HOZ A;  2FF2 A;  3FZ0 A;  1R4F A;  3MKN A;  4I73 A;  5TSQ A;  1Q8F A;  1KIE A;  2MAS A;  3B9G A;  1YOE A;  4I74 A;  4KPO A;  3T8I A;  1KIC A;  2C40 A;  4I71 A;  2YHG A;  3MKM A;  3EPW A;  3B9X A;  4P5F A;  4KPN A;  3G5I A;  3EPX A;  4KL0 A;  1EZR A;  4I72 A;  1MAS A;  2FF1 A;  3T8J A;  4I75 A;  4I70 A; 
#chains in the Genus database with same CATH topology
 1HP0 A;  4WR2 A;  1HOZ A;  2FF2 A;  3FZ0 A;  1R4F A;  3MKN A;  4I73 A;  5TSQ A;  1Q8F A;  1KIE A;  2MAS A;  3B9G A;  1YOE A;  4I74 A;  4KPO A;  3T8I A;  1KIC A;  2C40 A;  4I71 A;  2YHG A;  3MKM A;  3EPW A;  3B9X A;  4P5F A;  4KPN A;  3G5I A;  3EPX A;  4KL0 A;  1EZR A;  4I72 A;  1MAS A;  2FF1 A;  3T8J A;  4I75 A;  4I70 A; 
#chains in the Genus database with same CATH homology
 1HP0 A;  4WR2 A;  1HOZ A;  2FF2 A;  3FZ0 A;  1R4F A;  3MKN A;  4I73 A;  5TSQ A;  1Q8F A;  1KIE A;  2MAS A;  3B9G A;  1YOE A;  4I74 A;  4KPO A;  3T8I A;  1KIC A;  2C40 A;  4I71 A;  2YHG A;  3MKM A;  3EPW A;  3B9X A;  4P5F A;  4KPN A;  3G5I A;  3EPX A;  4KL0 A;  1EZR A;  4I72 A;  1MAS A;  2FF1 A;  3T8J A;  4I75 A;  4I70 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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