2HPRA

Histidine-containing phosphocarrier protein hpr mutant with met 51 replaced by val and ser 83 replaced by cys (m51v, s83c)
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
87
structure length
86
Chain Sequence
AQKTFKVTADSGIHARPATVLVQTASKYDADVNLEYNGKTVNLKSIMGVVSLGIAKGAEITISASGADENDALNALEETMKEGLGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined structures of the active Ser83-->Cys and impaired Ser46-->Asp histidine-containing phosphocarrier proteins.
pubmed doi rcsb
molecule tags Phosphotransferase
source organism Bacillus subtilis
molecule keywords HISTIDINE-CONTAINING PHOSPHOCARRIER PROTEIN HPR
total genus 27
structure length 86
sequence length 87
ec nomenclature
pdb deposition date 1992-09-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00381 PTS-HPr PTS HPr component phosphorylation site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1340.10 Alpha Beta 2-Layer Sandwich Histidine-containing Protein; Chain: A; HPr-like 2hprA00
3EZAB 1KA5A 1GGRB 2LRKD 3LE5A 1PTFA 2XDFC 3EZBB 2AK7A 1K1CA 3OQOD 1J6TB 1MO1B 3CCDA 3OQMD 2HIDA 1Y50A 3EZEB 1TXEA 2LRLD 1CM3A 1QR5A 1SPHA 1Y51A 1MO1A 1PFHA 2FEPS 2NZUL 4XWJB 1OPDA 5T17A 1FU0A 5T1OA 1KKMH 3OQND 2RLZA 3LFGA 1HDNA 3LE3A 1MU4A 1JEMA 1QFRA 1Y4YA 1CM2A 3IHSA 1RZRL 2HPRA 2OENL 1POHA 2JELP 1PCHA 3LE1A 2NZVL 1KKLH 3LNWA 1ZVVJ 5T1NA 1VRCC
chains in the Genus database with same CATH superfamily
3EZAB 1KA5A 1GGRB 2LRKD 3LE5A 1PTFA 2XDFC 3EZBB 2AK7A 1K1CA 3OQOD 1J6TB 1MO1B 3CCDA 3OQMD 2HIDA 1Y50A 3EZEB 1TXEA 2LRLD 1CM3A 1QR5A 1SPHA 1MO1A 1J5YA 1PFHA 1Y51A 2FEPS 2NZUL 1OPDA 4XWJB 1FU0A 5T17A 5T1OA 1KKMH 3OQND 2RLZA 3LFGA 1HDNA 3LE3A 1MU4A 1JEMA 1QFRA 1Y4YA 1CM2A 3IHSA 1RZRL 2HPRA 2OENL 1POHA 2JELP 1PCHA 3LE1A 2NZVL 1KKLH 3LNWA 1ZVVJ 5T1NA 1VRCC
chains in the Genus database with same CATH topology
3EZAB 1KA5A 1GGRB 2LRKD 3LE5A 1PTFA 2XDFC 3EZBB 2AK7A 1K1CA 3OQOD 1J6TB 1MO1B 3CCDA 3OQMD 2HIDA 1Y50A 3EZEB 1TXEA 2LRLD 1CM3A 1QR5A 1SPHA 1Y51A 1MO1A 1PFHA 2FEPS 2NZUL 4XWJB 1OPDA 5T17A 1FU0A 5T1OA 1KKMH 3OQND 2RLZA 3LFGA 1HDNA 3LE3A 1MU4A 1JEMA 1QFRA 1Y4YA 1CM2A 3IHSA 1RZRL 2HPRA 2OENL 1POHA 2JELP 1PCHA 3LE1A 2NZVL 1KKLH 3LNWA 1ZVVJ 5T1NA 1VRCC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EZA B;  1KA5 A;  1GGR B;  2LRK D;  3LE5 A;  1PTF A;  2XDF C;  3EZB B;  2AK7 A;  1K1C A;  3OQO D;  1J6T B;  1MO1 B;  3CCD A;  3OQM D;  2HID A;  1Y50 A;  3EZE B;  1TXE A;  2LRL D;  1CM3 A;  1QR5 A;  1SPH A;  1Y51 A;  1MO1 A;  1PFH A;  2FEP S;  2NZU L;  4XWJ B;  1OPD A;  5T17 A;  1FU0 A;  5T1O A;  1KKM H;  3OQN D;  2RLZ A;  3LFG A;  1HDN A;  3LE3 A;  1MU4 A;  1JEM A;  1QFR A;  1Y4Y A;  1CM2 A;  3IHS A;  1RZR L;  2HPR A;  2OEN L;  1POH A;  2JEL P;  1PCH A;  3LE1 A;  2NZV L;  1KKL H;  3LNW A;  1ZVV J;  5T1N A;  1VRC C; 
#chains in the Genus database with same CATH topology
 3EZA B;  1KA5 A;  1GGR B;  2LRK D;  3LE5 A;  1PTF A;  2XDF C;  3EZB B;  2AK7 A;  1K1C A;  3OQO D;  1J6T B;  1MO1 B;  3CCD A;  3OQM D;  2HID A;  1Y50 A;  3EZE B;  1TXE A;  2LRL D;  1CM3 A;  1QR5 A;  1SPH A;  1MO1 A;  1J5Y A;  1PFH A;  1Y51 A;  2FEP S;  2NZU L;  1OPD A;  4XWJ B;  1FU0 A;  5T17 A;  5T1O A;  1KKM H;  3OQN D;  2RLZ A;  3LFG A;  1HDN A;  3LE3 A;  1MU4 A;  1JEM A;  1QFR A;  1Y4Y A;  1CM2 A;  3IHS A;  1RZR L;  2HPR A;  2OEN L;  1POH A;  2JEL P;  1PCH A;  3LE1 A;  2NZV L;  1KKL H;  3LNW A;  1ZVV J;  5T1N A;  1VRC C; 
#chains in the Genus database with same CATH homology
 3EZA B;  1KA5 A;  1GGR B;  2LRK D;  3LE5 A;  1PTF A;  2XDF C;  3EZB B;  2AK7 A;  1K1C A;  3OQO D;  1J6T B;  1MO1 B;  3CCD A;  3OQM D;  2HID A;  1Y50 A;  3EZE B;  1TXE A;  2LRL D;  1CM3 A;  1QR5 A;  1SPH A;  1Y51 A;  1MO1 A;  1PFH A;  2FEP S;  2NZU L;  4XWJ B;  1OPD A;  5T17 A;  1FU0 A;  5T1O A;  1KKM H;  3OQN D;  2RLZ A;  3LFG A;  1HDN A;  3LE3 A;  1MU4 A;  1JEM A;  1QFR A;  1Y4Y A;  1CM2 A;  3IHS A;  1RZR L;  2HPR A;  2OEN L;  1POH A;  2JEL P;  1PCH A;  3LE1 A;  2NZV L;  1KKL H;  3LNW A;  1ZVV J;  5T1N A;  1VRC C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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