2KY6A

Structure of arc92vbd/med25acid
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
166
structure length
166
Chain Sequence
GEFGQQSVSNKLLAWSGVLEWQEKPKPASVDANTKLTRSLPCQVYVNHGENLKTEQWPQKLIMQLIPQQLLTTLGPLFRNSRMVQFHFTNKDLESLKGLYRIMGNGFAGCVHFPHTAPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVNGIRQVITNHKQVQQQKLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the VP16 transactivator target in the Mediator.
pubmed doi rcsb
molecule keywords Mediator of RNA polymerase II transcription subunit 25
molecule tags Transcription regulator
source organism Homo sapiens
total genus 44
structure length 166
sequence length 166
ec nomenclature
pdb deposition date 2010-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF11232 Med25 Mediator complex subunit 25 PTOV activation and synapsin 2
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.290.30 Mainly Beta Beta Barrel Ku70; Chain: A; Domain 2 Ku70; Chain: A; Domain 2 2ky6A00
2KY6A 2L23A 2L6UA 2XNFA
chains in the Genus database with same CATH superfamily
2XNFA 1OW1A 2L23A 2L6UA 1JEYB 1JEYA 1JEQB 1JEQA 2RT5A 2KY6A 3TIXB
chains in the Genus database with same CATH topology
2XNFA 1OW1A 2L23A 2L6UA 1JEYB 1JEYA 1JEQB 1JEQA 2RT5A 2KY6A 3TIXB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KY6 A;  2L23 A;  2L6U A;  2XNF A; 
#chains in the Genus database with same CATH topology
 2XNF A;  1OW1 A;  2L23 A;  2L6U A;  1JEY B;  1JEY A;  1JEQ B;  1JEQ A;  2RT5 A;  2KY6 A;  3TIX B; 
#chains in the Genus database with same CATH homology
 2XNF A;  1OW1 A;  2L23 A;  2L6U A;  1JEY B;  1JEY A;  1JEQ B;  1JEQ A;  2RT5 A;  2KY6 A;  3TIX B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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