2LI8A

The solution structure of the lin28-znf domains bound to aggagau of pre-let-7 mirna
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
63
Chain Sequence
PKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.
pubmed doi rcsb
molecule tags Transcription/rna
source organism Homo sapiens
molecule keywords Protein lin-28 homolog A
total genus 6
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2011-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00098 zf-CCHC Zinc knuckle
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.60.10 Few Secondary Structures Irregular HIV-1 Nucleocapsid Protein Zinc finger, CCHC-type 2li8A00
3TS2A 1Q3YA 1Q3ZA 1WWGA 2YSAA 2M3ZA 1F6UA 1AAFA 2JZWA 2CQFA 1MFSA 1ESKA 2LI8A 1WWDA 3NYBB 3TRZA 1WWEA 2L4LA 1A1TA 2EC7A 1WWFA 3TS0A 1BJ6A 2IHXA 2EXFA 1U6PA 1A6BB
chains in the Genus database with same CATH superfamily
3TS2A 1Q3YA 1Q3ZA 1WWGA 2YSAA 2M3ZA 1F6UA 1AAFA 2JZWA 2CQFA 1MFSA 1ESKA 2LI8A 1WWDA 3NYBB 3TRZA 1WWEA 2L4LA 1A1TA 2EC7A 1WWFA 3TS0A 1BJ6A 2IHXA 2EXFA 1U6PA 1A6BB
chains in the Genus database with same CATH topology
3TS2A 1Q3YA 1Q3ZA 1WWGA 2YSAA 2M3ZA 1F6UA 1AAFA 2JZWA 2CQFA 1MFSA 1ESKA 2LI8A 1WWDA 3NYBB 3TRZA 1WWEA 2L4LA 1A1TA 2EC7A 1WWFA 3TS0A 1BJ6A 2IHXA 2EXFA 1U6PA 1A6BB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3TS2 A;  1Q3Y A;  1Q3Z A;  1WWG A;  2YSA A;  2M3Z A;  1F6U A;  1AAF A;  2JZW A;  2CQF A;  1MFS A;  1ESK A;  2LI8 A;  1WWD A;  3NYB B;  3TRZ A;  1WWE A;  2L4L A;  1A1T A;  2EC7 A;  1WWF A;  3TS0 A;  1BJ6 A;  2IHX A;  2EXF A;  1U6P A;  1A6B B; 
#chains in the Genus database with same CATH topology
 3TS2 A;  1Q3Y A;  1Q3Z A;  1WWG A;  2YSA A;  2M3Z A;  1F6U A;  1AAF A;  2JZW A;  2CQF A;  1MFS A;  1ESK A;  2LI8 A;  1WWD A;  3NYB B;  3TRZ A;  1WWE A;  2L4L A;  1A1T A;  2EC7 A;  1WWF A;  3TS0 A;  1BJ6 A;  2IHX A;  2EXF A;  1U6P A;  1A6B B; 
#chains in the Genus database with same CATH homology
 3TS2 A;  1Q3Y A;  1Q3Z A;  1WWG A;  2YSA A;  2M3Z A;  1F6U A;  1AAF A;  2JZW A;  2CQF A;  1MFS A;  1ESK A;  2LI8 A;  1WWD A;  3NYB B;  3TRZ A;  1WWE A;  2L4L A;  1A1T A;  2EC7 A;  1WWF A;  3TS0 A;  1BJ6 A;  2IHX A;  2EXF A;  1U6P A;  1A6B B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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