2LI8A

The solution structure of the lin28-znf domains bound to aggagau of pre-let-7 mirna
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
63
structure length
63
Chain Sequence
PKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSAQG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.
pubmed doi rcsb
molecule keywords Protein lin-28 homolog A
molecule tags Transcription/rna
source organism Homo sapiens
total genus 6
structure length 63
sequence length 63
ec nomenclature
pdb deposition date 2011-08-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00098 zf-CCHC Zinc knuckle
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.60.10 Few Secondary Structures Irregular HIV-1 Nucleocapsid Protein Zinc finger, CCHC-type 2li8A00
1A1TA 2EC7A 1WWGA 2IHXA 1A6BB 1WWDA 1Q3ZA 1AAFA 1Q3YA 2M3ZA 2CQFA 2EXFA 1BJ6A 2LI8A 1U6PA 2L4LA 1WWFA 2JZWA 3TS2A 3NYBB 3TS0A 1ESKA 2YSAA 1WWEA 1MFSA 3TRZA 1F6UA
chains in the Genus database with same CATH superfamily
1A1TA 2EC7A 1WWGA 2IHXA 1A6BB 1WWDA 1Q3ZA 1AAFA 1Q3YA 2M3ZA 2CQFA 2EXFA 1BJ6A 2LI8A 1U6PA 2L4LA 1WWFA 2JZWA 3TS2A 3NYBB 3TS0A 1ESKA 2YSAA 1WWEA 1MFSA 3TRZA 1F6UA
chains in the Genus database with same CATH topology
1A1TA 2EC7A 1WWGA 2IHXA 1A6BB 1WWDA 1Q3ZA 1AAFA 1Q3YA 2M3ZA 2CQFA 2EXFA 1BJ6A 2LI8A 1U6PA 2L4LA 1WWFA 2JZWA 3TS2A 3NYBB 3TS0A 1ESKA 2YSAA 1WWEA 1MFSA 3TRZA 1F6UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A1T A;  2EC7 A;  1WWG A;  2IHX A;  1A6B B;  1WWD A;  1Q3Z A;  1AAF A;  1Q3Y A;  2M3Z A;  2CQF A;  2EXF A;  1BJ6 A;  2LI8 A;  1U6P A;  2L4L A;  1WWF A;  2JZW A;  3TS2 A;  3NYB B;  3TS0 A;  1ESK A;  2YSA A;  1WWE A;  1MFS A;  3TRZ A;  1F6U A; 
#chains in the Genus database with same CATH topology
 1A1T A;  2EC7 A;  1WWG A;  2IHX A;  1A6B B;  1WWD A;  1Q3Z A;  1AAF A;  1Q3Y A;  2M3Z A;  2CQF A;  2EXF A;  1BJ6 A;  2LI8 A;  1U6P A;  2L4L A;  1WWF A;  2JZW A;  3TS2 A;  3NYB B;  3TS0 A;  1ESK A;  2YSA A;  1WWE A;  1MFS A;  3TRZ A;  1F6U A; 
#chains in the Genus database with same CATH homology
 1A1T A;  2EC7 A;  1WWG A;  2IHX A;  1A6B B;  1WWD A;  1Q3Z A;  1AAF A;  1Q3Y A;  2M3Z A;  2CQF A;  2EXF A;  1BJ6 A;  2LI8 A;  1U6P A;  2L4L A;  1WWF A;  2JZW A;  3TS2 A;  3NYB B;  3TS0 A;  1ESK A;  2YSA A;  1WWE A;  1MFS A;  3TRZ A;  1F6U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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