2MAS | Genus

Total Genus 104

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	104
sequence length	313
structure length	313
Chain Sequence	AKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITGVPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKTITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVFNESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAVHDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKFWGLVLDALERIGDP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Trypanosomal nucleoside hydrolase. A novel mechanism from the structure with a transition-state inhibitor. pubmed doi rcsb
molecule keywords	INOSINE-URIDINE NUCLEOSIDE N-RIBOHYDROLASE
molecule tags	Hydrolase
source organism	Crithidia fasciculata
total genus	104
structure length	313
sequence length	313
chains with identical sequence	B, C, D
ec nomenclature	ec 3.2.2.2: Inosine nucleosidase.
pdb deposition date	1996-10-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	2masA00

4I70A 2C40A 3FZ0A 2FF1A 3B9XA 4KL0A 1KIEA 1Q8FA 5TSQA 4I72A 1YOEA 3MKMA 4WR2A 2MASA 1R4FA 3EPWA 2YHGA 3B9GA 1EZRA 1HOZA 1MASA 4KPOA 4P5FA 4I75A 4KPNA 1KICA 4I71A 4I73A 2FF2A 3G5IA 3T8IA 3T8JA 3EPXA 4I74A 1HP0A 3MKNA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4I70 A;  2C40 A;  3FZ0 A;  2FF1 A;  3B9X A;  4KL0 A;  1KIE A;  1Q8F A;  5TSQ A;  4I72 A;  1YOE A;  3MKM A;  4WR2 A;  2MAS A;  1R4F A;  3EPW A;  2YHG A;  3B9G A;  1EZR A;  1HOZ A;  1MAS A;  4KPO A;  4P5F A;  4I75 A;  4KPN A;  1KIC A;  4I71 A;  4I73 A;  2FF2 A;  3G5I A;  3T8I A;  3T8J A;  3EPX A;  4I74 A;  1HP0 A;  3MKN A; 
#chains in the Genus database with same CATH topology
 4I70 A;  2C40 A;  3FZ0 A;  2FF1 A;  3B9X A;  4KL0 A;  1KIE A;  1Q8F A;  5TSQ A;  4I72 A;  1YOE A;  3MKM A;  4WR2 A;  2MAS A;  1R4F A;  3EPW A;  2YHG A;  3B9G A;  1EZR A;  1HOZ A;  1MAS A;  4KPO A;  4P5F A;  4I75 A;  4KPN A;  1KIC A;  4I71 A;  4I73 A;  2FF2 A;  3G5I A;  3T8I A;  3T8J A;  3EPX A;  4I74 A;  1HP0 A;  3MKN A; 
#chains in the Genus database with same CATH homology
 4I70 A;  2C40 A;  3FZ0 A;  2FF1 A;  3B9X A;  4KL0 A;  1KIE A;  1Q8F A;  5TSQ A;  4I72 A;  1YOE A;  3MKM A;  4WR2 A;  2MAS A;  1R4F A;  3EPW A;  2YHG A;  3B9G A;  1EZR A;  1HOZ A;  1MAS A;  4KPO A;  4P5F A;  4I75 A;  4KPN A;  1KIC A;  4I71 A;  4I73 A;  2FF2 A;  3G5I A;  3T8I A;  3T8J A;  3EPX A;  4I74 A;  1HP0 A;  3MKN A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2MASA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations