2NOWA

An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
Total Genus 155
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
155
sequence length
385
structure length
368
Chain Sequence
PAVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVEINAAIAGLVGAYLIPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKDDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Ammonia channel
publication title An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
pubmed doi rcsb
source organism Escherichia coli
total genus 155
structure length 368
sequence length 385
ec nomenclature
pdb deposition date 2006-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00909 Ammonium_transp Ammonium Transporter Family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3430.10 Mainly Alpha Orthogonal Bundle Ammonium transporter fold Ammonium transporter AmtB like domains 2nowA00
2NPEA 1XQFA 5FUFA 2NOPA 3K3FA 3C1HA 3ME1A 3B9YA 2NPJA 5AEZA 1U77A 2NOWA 2NMRA 2NPKA 3C1IA 3C1GA 5AEXA 2B2HA 1U7CA 5AH3A 2B2FA 3K3GA 2NPDA 2NUUA 2NS1A 4EZDA 3B9ZA 3M6EA 1XQEA 2B2JA 2NPGA 4NH2A 1U7GA 3BHSA 5AIDA 2B2IA 3HD6A 4EZCA 3C1JA 3B9WA 5AF1A 2NPCA
chains in the Genus database with same CATH superfamily
2NPEA 1XQFA 5FUFA 2NOPA 3K3FA 3C1HA 3ME1A 3B9YA 2NPJA 5AEZA 1U77A 2NOWA 2NMRA 2NPKA 3C1IA 3C1GA 5AEXA 2B2HA 1U7CA 5AH3A 2B2FA 3K3GA 2NPDA 2NUUA 2NS1A 4EZDA 3B9ZA 3M6EA 1XQEA 2B2JA 2NPGA 4NH2A 1U7GA 3BHSA 5AIDA 2B2IA 3HD6A 4EZCA 3C1JA 3B9WA 5AF1A 2NPCA
chains in the Genus database with same CATH topology
2NPEA 1XQFA 5FUFA 2NOPA 3K3FA 3C1HA 3ME1A 3B9YA 2NPJA 5AEZA 1U77A 2NOWA 2NMRA 2NPKA 3C1IA 3C1GA 5AEXA 2B2HA 1U7CA 5AH3A 2B2FA 3K3GA 2NPDA 2NUUA 2NS1A 4EZDA 3B9ZA 3M6EA 1XQEA 2B2JA 2NPGA 4NH2A 1U7GA 3BHSA 5AIDA 2B2IA 3HD6A 4EZCA 3C1JA 3B9WA 5AF1A 2NPCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NPE A;  1XQF A;  5FUF A;  2NOP A;  3K3F A;  3C1H A;  3ME1 A;  3B9Y A;  2NPJ A;  5AEZ A;  1U77 A;  2NOW A;  2NMR A;  2NPK A;  3C1I A;  3C1G A;  5AEX A;  2B2H A;  1U7C A;  5AH3 A;  2B2F A;  3K3G A;  2NPD A;  2NUU A;  2NS1 A;  4EZD A;  3B9Z A;  3M6E A;  1XQE A;  2B2J A;  2NPG A;  4NH2 A;  1U7G A;  3BHS A;  5AID A;  2B2I A;  3HD6 A;  4EZC A;  3C1J A;  3B9W A;  5AF1 A;  2NPC A; 
#chains in the Genus database with same CATH topology
 2NPE A;  1XQF A;  5FUF A;  2NOP A;  3K3F A;  3C1H A;  3ME1 A;  3B9Y A;  2NPJ A;  5AEZ A;  1U77 A;  2NOW A;  2NMR A;  2NPK A;  3C1I A;  3C1G A;  5AEX A;  2B2H A;  1U7C A;  5AH3 A;  2B2F A;  3K3G A;  2NPD A;  2NUU A;  2NS1 A;  4EZD A;  3B9Z A;  3M6E A;  1XQE A;  2B2J A;  2NPG A;  4NH2 A;  1U7G A;  3BHS A;  5AID A;  2B2I A;  3HD6 A;  4EZC A;  3C1J A;  3B9W A;  5AF1 A;  2NPC A; 
#chains in the Genus database with same CATH homology
 2NPE A;  1XQF A;  5FUF A;  2NOP A;  3K3F A;  3C1H A;  3ME1 A;  3B9Y A;  2NPJ A;  5AEZ A;  1U77 A;  2NOW A;  2NMR A;  2NPK A;  3C1I A;  3C1G A;  5AEX A;  2B2H A;  1U7C A;  5AH3 A;  2B2F A;  3K3G A;  2NPD A;  2NUU A;  2NS1 A;  4EZD A;  3B9Z A;  3M6E A;  1XQE A;  2B2J A;  2NPG A;  4NH2 A;  1U7G A;  3BHS A;  5AID A;  2B2I A;  3HD6 A;  4EZC A;  3C1J A;  3B9W A;  5AF1 A;  2NPC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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