2NPJA

An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
Total Genus 152
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
152
sequence length
384
structure length
363
Chain Sequence
AVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLPCDVFGVFGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Ammonia channel
publication title An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
pubmed doi rcsb
source organism Escherichia coli
total genus 152
structure length 363
sequence length 384
ec nomenclature
pdb deposition date 2006-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00909 Ammonium_transp Ammonium Transporter Family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3430.10 Mainly Alpha Orthogonal Bundle Ammonium transporter fold Ammonium transporter AmtB like domains 2npjA00
5AIDA 2NPDA 2NOWA 5AEZA 2NPEA 5AH3A 1U7CA 4EZDA 2B2HA 2NUUA 3C1HA 3M6EA 2B2JA 4NH2A 2NS1A 5FUFA 2NPJA 3C1GA 2NMRA 2NOPA 3K3FA 1U77A 5AEXA 1U7GA 4EZCA 2B2IA 5AF1A 3ME1A 3B9WA 3K3GA 3C1IA 3B9YA 1XQFA 3BHSA 3HD6A 2NPKA 2NPCA 2NPGA 3B9ZA 2B2FA 1XQEA 3C1JA
chains in the Genus database with same CATH superfamily
5AIDA 2NPDA 2NOWA 5AEZA 2NPEA 5AH3A 1U7CA 4EZDA 2B2HA 2NUUA 3C1HA 3M6EA 2B2JA 4NH2A 2NS1A 5FUFA 2NPJA 3C1GA 2NMRA 2NOPA 3K3FA 1U77A 5AEXA 1U7GA 4EZCA 2B2IA 5AF1A 3ME1A 3B9WA 3K3GA 3C1IA 3B9YA 1XQFA 3BHSA 3HD6A 2NPKA 2NPCA 2NPGA 3B9ZA 2B2FA 1XQEA 3C1JA
chains in the Genus database with same CATH topology
5AIDA 2NPDA 2NOWA 5AEZA 2NPEA 5AH3A 1U7CA 4EZDA 2B2HA 2NUUA 3C1HA 3M6EA 2B2JA 4NH2A 2NS1A 5FUFA 2NPJA 3C1GA 2NMRA 2NOPA 3K3FA 1U77A 5AEXA 1U7GA 4EZCA 2B2IA 5AF1A 3ME1A 3B9WA 3K3GA 3C1IA 3B9YA 1XQFA 3BHSA 3HD6A 2NPKA 2NPCA 2NPGA 3B9ZA 2B2FA 1XQEA 3C1JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AID A;  2NPD A;  2NOW A;  5AEZ A;  2NPE A;  5AH3 A;  1U7C A;  4EZD A;  2B2H A;  2NUU A;  3C1H A;  3M6E A;  2B2J A;  4NH2 A;  2NS1 A;  5FUF A;  2NPJ A;  3C1G A;  2NMR A;  2NOP A;  3K3F A;  1U77 A;  5AEX A;  1U7G A;  4EZC A;  2B2I A;  5AF1 A;  3ME1 A;  3B9W A;  3K3G A;  3C1I A;  3B9Y A;  1XQF A;  3BHS A;  3HD6 A;  2NPK A;  2NPC A;  2NPG A;  3B9Z A;  2B2F A;  1XQE A;  3C1J A; 
#chains in the Genus database with same CATH topology
 5AID A;  2NPD A;  2NOW A;  5AEZ A;  2NPE A;  5AH3 A;  1U7C A;  4EZD A;  2B2H A;  2NUU A;  3C1H A;  3M6E A;  2B2J A;  4NH2 A;  2NS1 A;  5FUF A;  2NPJ A;  3C1G A;  2NMR A;  2NOP A;  3K3F A;  1U77 A;  5AEX A;  1U7G A;  4EZC A;  2B2I A;  5AF1 A;  3ME1 A;  3B9W A;  3K3G A;  3C1I A;  3B9Y A;  1XQF A;  3BHS A;  3HD6 A;  2NPK A;  2NPC A;  2NPG A;  3B9Z A;  2B2F A;  1XQE A;  3C1J A; 
#chains in the Genus database with same CATH homology
 5AID A;  2NPD A;  2NOW A;  5AEZ A;  2NPE A;  5AH3 A;  1U7C A;  4EZD A;  2B2H A;  2NUU A;  3C1H A;  3M6E A;  2B2J A;  4NH2 A;  2NS1 A;  5FUF A;  2NPJ A;  3C1G A;  2NMR A;  2NOP A;  3K3F A;  1U77 A;  5AEX A;  1U7G A;  4EZC A;  2B2I A;  5AF1 A;  3ME1 A;  3B9W A;  3K3G A;  3C1I A;  3B9Y A;  1XQF A;  3BHS A;  3HD6 A;  2NPK A;  2NPC A;  2NPG A;  3B9Z A;  2B2F A;  1XQE A;  3C1J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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