2NPGA

An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
Total Genus 155
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
155
sequence length
385
structure length
366
Chain Sequence
PAVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKDPCDVFGVFGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRVP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transport protein
molecule keywords Ammonia channel
publication title An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
pubmed doi rcsb
source organism Escherichia coli
total genus 155
structure length 366
sequence length 385
ec nomenclature
pdb deposition date 2006-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00909 Ammonium_transp Ammonium Transporter Family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3430.10 Mainly Alpha Orthogonal Bundle Ammonium transporter fold Ammonium transporter AmtB like domains 2npgA00
5FUFA 3BHSA 3C1IA 5AF1A 2NUUA 2NOWA 3K3GA 2NPGA 2NPEA 2B2FA 5AEXA 2NPJA 2NPKA 3C1JA 5AIDA 2NS1A 2NPDA 1U7CA 2NMRA 2B2IA 3C1HA 3K3FA 1U7GA 3B9ZA 2B2JA 3B9YA 1U77A 4NH2A 3HD6A 1XQEA 1XQFA 3B9WA 4EZCA 5AEZA 5AH3A 2NOPA 3C1GA 2B2HA 4EZDA 3ME1A 3M6EA 2NPCA
chains in the Genus database with same CATH superfamily
5FUFA 3BHSA 3C1IA 5AF1A 2NUUA 2NOWA 3K3GA 2NPGA 2NPEA 2B2FA 5AEXA 2NPJA 2NPKA 3C1JA 5AIDA 2NS1A 2NPDA 1U7CA 2NMRA 2B2IA 3C1HA 3K3FA 1U7GA 3B9ZA 2B2JA 3B9YA 1U77A 4NH2A 3HD6A 1XQEA 1XQFA 3B9WA 4EZCA 5AEZA 5AH3A 2NOPA 3C1GA 2B2HA 4EZDA 3ME1A 3M6EA 2NPCA
chains in the Genus database with same CATH topology
5FUFA 3BHSA 3C1IA 5AF1A 2NUUA 2NOWA 3K3GA 2NPGA 2NPEA 2B2FA 5AEXA 2NPJA 2NPKA 3C1JA 5AIDA 2NS1A 2NPDA 1U7CA 2NMRA 2B2IA 3C1HA 3K3FA 1U7GA 3B9ZA 2B2JA 3B9YA 1U77A 4NH2A 3HD6A 1XQEA 1XQFA 3B9WA 4EZCA 5AEZA 5AH3A 2NOPA 3C1GA 2B2HA 4EZDA 3ME1A 3M6EA 2NPCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FUF A;  3BHS A;  3C1I A;  5AF1 A;  2NUU A;  2NOW A;  3K3G A;  2NPG A;  2NPE A;  2B2F A;  5AEX A;  2NPJ A;  2NPK A;  3C1J A;  5AID A;  2NS1 A;  2NPD A;  1U7C A;  2NMR A;  2B2I A;  3C1H A;  3K3F A;  1U7G A;  3B9Z A;  2B2J A;  3B9Y A;  1U77 A;  4NH2 A;  3HD6 A;  1XQE A;  1XQF A;  3B9W A;  4EZC A;  5AEZ A;  5AH3 A;  2NOP A;  3C1G A;  2B2H A;  4EZD A;  3ME1 A;  3M6E A;  2NPC A; 
#chains in the Genus database with same CATH topology
 5FUF A;  3BHS A;  3C1I A;  5AF1 A;  2NUU A;  2NOW A;  3K3G A;  2NPG A;  2NPE A;  2B2F A;  5AEX A;  2NPJ A;  2NPK A;  3C1J A;  5AID A;  2NS1 A;  2NPD A;  1U7C A;  2NMR A;  2B2I A;  3C1H A;  3K3F A;  1U7G A;  3B9Z A;  2B2J A;  3B9Y A;  1U77 A;  4NH2 A;  3HD6 A;  1XQE A;  1XQF A;  3B9W A;  4EZC A;  5AEZ A;  5AH3 A;  2NOP A;  3C1G A;  2B2H A;  4EZD A;  3ME1 A;  3M6E A;  2NPC A; 
#chains in the Genus database with same CATH homology
 5FUF A;  3BHS A;  3C1I A;  5AF1 A;  2NUU A;  2NOW A;  3K3G A;  2NPG A;  2NPE A;  2B2F A;  5AEX A;  2NPJ A;  2NPK A;  3C1J A;  5AID A;  2NS1 A;  2NPD A;  1U7C A;  2NMR A;  2B2I A;  3C1H A;  3K3F A;  1U7G A;  3B9Z A;  2B2J A;  3B9Y A;  1U77 A;  4NH2 A;  3HD6 A;  1XQE A;  1XQF A;  3B9W A;  4EZC A;  5AEZ A;  5AH3 A;  2NOP A;  3C1G A;  2B2H A;  4EZD A;  3ME1 A;  3M6E A;  2NPC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...