2NPEA

An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
385
structure length
367
Chain Sequence
PAVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTLSYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLPHNLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRDPCDVFGVAGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLADLTVGLRVP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
molecule keywords Ammonia channel
publication title An unusual twin-his arrangement in the pore of ammonia channels is essential for substrate conductance
pubmed doi rcsb
source organism Escherichia coli
total genus 151
structure length 367
sequence length 385
ec nomenclature
pdb deposition date 2006-10-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00909 Ammonium_transp Ammonium Transporter Family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.3430.10 Mainly Alpha Orthogonal Bundle Ammonium transporter fold Ammonium transporter AmtB like domains 2npeA00
4NH2A 2NUUA 5AEZA 2NPCA 3B9ZA 3C1IA 2B2IA 2NPGA 4EZDA 3ME1A 5AEXA 5FUFA 3C1GA 3B9YA 2B2JA 3HD6A 2B2HA 4EZCA 2NPEA 1U7CA 5AH3A 2NMRA 3K3GA 2NPDA 3C1JA 3K3FA 2NOWA 2NS1A 1U7GA 2NPKA 2NPJA 1XQFA 1U77A 1XQEA 3B9WA 3BHSA 5AF1A 5AIDA 3M6EA 2B2FA 2NOPA 3C1HA
chains in the Genus database with same CATH superfamily
4NH2A 2NUUA 5AEZA 2NPCA 3B9ZA 3C1IA 2B2IA 2NPGA 4EZDA 3ME1A 5AEXA 5FUFA 3C1GA 3B9YA 2B2JA 3HD6A 2B2HA 4EZCA 2NPEA 1U7CA 5AH3A 2NMRA 3K3GA 2NPDA 3C1JA 3K3FA 2NOWA 2NS1A 1U7GA 2NPKA 2NPJA 1XQFA 1U77A 1XQEA 3B9WA 3BHSA 5AF1A 5AIDA 3M6EA 2B2FA 2NOPA 3C1HA
chains in the Genus database with same CATH topology
4NH2A 2NUUA 5AEZA 2NPCA 3B9ZA 3C1IA 2B2IA 2NPGA 4EZDA 3ME1A 5AEXA 5FUFA 3C1GA 3B9YA 2B2JA 3HD6A 2B2HA 4EZCA 2NPEA 1U7CA 5AH3A 2NMRA 3K3GA 2NPDA 3C1JA 3K3FA 2NOWA 2NS1A 1U7GA 2NPKA 2NPJA 1XQFA 1U77A 1XQEA 3B9WA 3BHSA 5AF1A 5AIDA 3M6EA 2B2FA 2NOPA 3C1HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NH2 A;  2NUU A;  5AEZ A;  2NPC A;  3B9Z A;  3C1I A;  2B2I A;  2NPG A;  4EZD A;  3ME1 A;  5AEX A;  5FUF A;  3C1G A;  3B9Y A;  2B2J A;  3HD6 A;  2B2H A;  4EZC A;  2NPE A;  1U7C A;  5AH3 A;  2NMR A;  3K3G A;  2NPD A;  3C1J A;  3K3F A;  2NOW A;  2NS1 A;  1U7G A;  2NPK A;  2NPJ A;  1XQF A;  1U77 A;  1XQE A;  3B9W A;  3BHS A;  5AF1 A;  5AID A;  3M6E A;  2B2F A;  2NOP A;  3C1H A; 
#chains in the Genus database with same CATH topology
 4NH2 A;  2NUU A;  5AEZ A;  2NPC A;  3B9Z A;  3C1I A;  2B2I A;  2NPG A;  4EZD A;  3ME1 A;  5AEX A;  5FUF A;  3C1G A;  3B9Y A;  2B2J A;  3HD6 A;  2B2H A;  4EZC A;  2NPE A;  1U7C A;  5AH3 A;  2NMR A;  3K3G A;  2NPD A;  3C1J A;  3K3F A;  2NOW A;  2NS1 A;  1U7G A;  2NPK A;  2NPJ A;  1XQF A;  1U77 A;  1XQE A;  3B9W A;  3BHS A;  5AF1 A;  5AID A;  3M6E A;  2B2F A;  2NOP A;  3C1H A; 
#chains in the Genus database with same CATH homology
 4NH2 A;  2NUU A;  5AEZ A;  2NPC A;  3B9Z A;  3C1I A;  2B2I A;  2NPG A;  4EZD A;  3ME1 A;  5AEX A;  5FUF A;  3C1G A;  3B9Y A;  2B2J A;  3HD6 A;  2B2H A;  4EZC A;  2NPE A;  1U7C A;  5AH3 A;  2NMR A;  3K3G A;  2NPD A;  3C1J A;  3K3F A;  2NOW A;  2NS1 A;  1U7G A;  2NPK A;  2NPJ A;  1XQF A;  1U77 A;  1XQE A;  3B9W A;  3BHS A;  5AF1 A;  5AID A;  3M6E A;  2B2F A;  2NOP A;  3C1H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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