2RT5A

Structural insights into the recruitment of smrt by the co-repressor sharp under phosphorylative regulation
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
169
structure length
169
Chain Sequence
VDMVQLLKKYPIVWQGLLALKNDTAAVQLHFVSGNNVLAHRSLPLSEGGPPLRIAQRMRLEATQLEGVARRMTVETDYCLLLALPCGRDQEDVVSQTESLKAAFITYLQAKQAAGIINVPNPGSNQPAYVLQIFPPCEFSESHLSRLAPDLLASISNISPHLMIVIASV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into the Recruitment of SMRT by the Corepressor SHARP under Phosphorylative Regulation
pubmed doi rcsb
molecule keywords Msx2-interacting protein
molecule tags Transcription regulator
source organism Homo sapiens
total genus 43
structure length 169
sequence length 169
ec nomenclature
pdb deposition date 2013-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07744 SPOC SPOC domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.290.10 Mainly Beta Beta Barrel Ku70; Chain: A; Domain 2 Ku70; Chain: A; Domain 2 2rt5A00
1JEQA 1JEYA 1JEQB 1OW1A 1JEYB 2RT5A
chains in the Genus database with same CATH superfamily
3TIXB 1JEQA 2L6UA 1JEYA 1JEQB 2L23A 1OW1A 2XNFA 2RT5A 1JEYB 2KY6A
chains in the Genus database with same CATH topology
3TIXB 1JEQA 2L6UA 1JEYA 1JEQB 2L23A 1OW1A 2XNFA 2RT5A 1JEYB 2KY6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JEQ A;  1JEY A;  1JEQ B;  1OW1 A;  1JEY B;  2RT5 A; 
#chains in the Genus database with same CATH topology
 3TIX B;  1JEQ A;  2L6U A;  1JEY A;  1JEQ B;  2L23 A;  1OW1 A;  2XNF A;  2RT5 A;  1JEY B;  2KY6 A; 
#chains in the Genus database with same CATH homology
 3TIX B;  1JEQ A;  2L6U A;  1JEY A;  1JEQ B;  2L23 A;  1OW1 A;  2XNF A;  2RT5 A;  1JEY B;  2KY6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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