2EXFA

Solution structure of the hiv-1 nucleocapsid (ncp7(12-55)) complexed with the dna (-) primer binding site
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
44
structure length
44
Chain Sequence
NVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQAN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription.
pubmed doi rcsb
molecule tags Viral protein/dna
molecule keywords 5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*C)-3'
total genus 6
structure length 44
sequence length 44
ec nomenclature ec 2.7.7.49: RNA-directed DNA polymerase.
pdb deposition date 2005-11-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00098 zf-CCHC Zinc knuckle
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.60.10 Few Secondary Structures Irregular HIV-1 Nucleocapsid Protein Zinc finger, CCHC-type 2exfA00
2EXFA 2LI8A 2IHXA 1A6BB 1Q3ZA 3TRZA 1ESKA 2L4LA 1A1TA 1AAFA 2YSAA 3TS2A 1WWGA 1Q3YA 1WWFA 1WWEA 3NYBB 2EC7A 1F6UA 1WWDA 2M3ZA 3TS0A 1U6PA 1BJ6A 2CQFA 2JZWA 1MFSA
chains in the Genus database with same CATH superfamily
2EXFA 2LI8A 2IHXA 1A6BB 1Q3ZA 3TRZA 1ESKA 2L4LA 1A1TA 1AAFA 2YSAA 3TS2A 1WWGA 1Q3YA 1WWFA 1WWEA 3NYBB 2EC7A 1F6UA 1WWDA 2M3ZA 3TS0A 1U6PA 1BJ6A 2CQFA 2JZWA 1MFSA
chains in the Genus database with same CATH topology
2EXFA 2LI8A 2IHXA 1A6BB 1Q3ZA 3TRZA 1ESKA 2L4LA 1A1TA 1AAFA 2YSAA 3TS2A 1WWGA 1Q3YA 1WWFA 1WWEA 3NYBB 2EC7A 1F6UA 1WWDA 2M3ZA 3TS0A 1U6PA 1BJ6A 2CQFA 2JZWA 1MFSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EXF A;  2LI8 A;  2IHX A;  1A6B B;  1Q3Z A;  3TRZ A;  1ESK A;  2L4L A;  1A1T A;  1AAF A;  2YSA A;  3TS2 A;  1WWG A;  1Q3Y A;  1WWF A;  1WWE A;  3NYB B;  2EC7 A;  1F6U A;  1WWD A;  2M3Z A;  3TS0 A;  1U6P A;  1BJ6 A;  2CQF A;  2JZW A;  1MFS A; 
#chains in the Genus database with same CATH topology
 2EXF A;  2LI8 A;  2IHX A;  1A6B B;  1Q3Z A;  3TRZ A;  1ESK A;  2L4L A;  1A1T A;  1AAF A;  2YSA A;  3TS2 A;  1WWG A;  1Q3Y A;  1WWF A;  1WWE A;  3NYB B;  2EC7 A;  1F6U A;  1WWD A;  2M3Z A;  3TS0 A;  1U6P A;  1BJ6 A;  2CQF A;  2JZW A;  1MFS A; 
#chains in the Genus database with same CATH homology
 2EXF A;  2LI8 A;  2IHX A;  1A6B B;  1Q3Z A;  3TRZ A;  1ESK A;  2L4L A;  1A1T A;  1AAF A;  2YSA A;  3TS2 A;  1WWG A;  1Q3Y A;  1WWF A;  1WWE A;  3NYB B;  2EC7 A;  1F6U A;  1WWD A;  2M3Z A;  3TS0 A;  1U6P A;  1BJ6 A;  2CQF A;  2JZW A;  1MFS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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