3EPX | Genus

Total Genus 119

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	119
sequence length	326
structure length	322
Chain Sequence	AKNVVLDHDGNLDDFVAMVLLASNTEKVRLIGALCTDADCFVENGFNVTGKIMCLMHNNMNLPLFPIGKSAATAVNPFPKEWRCLAKNMDDMPILNIPENVELWDKIKAENEKYEGQQLLADLVMNSEEKVTICVTGPLSNVAWCIDKYGEKFTSKVEECVIMGGAVDVRGNVFLPSTDGTAEWNIYWDPASAKTVFGCPGLRRIMFSLDSTNTVPVRSPYVQRFGEQTNFLLSILVGTMWAMCTHCEGDGYYAWDALTAAYVVDQKVANVDPVPIDVVVDKQPNEGATVRTDAENYPLTFVARNPEAEFFLDMLLRSARAC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 322 atoms

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322 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors. pubmed doi rcsb
molecule keywords	IAG-nucleoside hydrolase
molecule tags	Hydrolase
source organism	Trypanosoma vivax
total genus	119
structure length	322
sequence length	326
chains with identical sequence	B
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2008-09-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	3epxA00

1HOZA 4I72A 1MASA 3B9XA 1HP0A 1KIEA 3FZ0A 2FF1A 2C40A 3B9GA 3T8JA 4I74A 3G5IA 4KL0A 3EPXA 4WR2A 1YOEA 3MKNA 3T8IA 1EZRA 5TSQA 2FF2A 4P5FA 4I75A 3MKMA 4I71A 1R4FA 2MASA 3EPWA 4KPOA 1KICA 2YHGA 4I70A 1Q8FA 4I73A 4KPNA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1HOZ A;  4I72 A;  1MAS A;  3B9X A;  1HP0 A;  1KIE A;  3FZ0 A;  2FF1 A;  2C40 A;  3B9G A;  3T8J A;  4I74 A;  3G5I A;  4KL0 A;  3EPX A;  4WR2 A;  1YOE A;  3MKN A;  3T8I A;  1EZR A;  5TSQ A;  2FF2 A;  4P5F A;  4I75 A;  3MKM A;  4I71 A;  1R4F A;  2MAS A;  3EPW A;  4KPO A;  1KIC A;  2YHG A;  4I70 A;  1Q8F A;  4I73 A;  4KPN A; 
#chains in the Genus database with same CATH topology
 1HOZ A;  4I72 A;  1MAS A;  3B9X A;  1HP0 A;  1KIE A;  3FZ0 A;  2FF1 A;  2C40 A;  3B9G A;  3T8J A;  4I74 A;  3G5I A;  4KL0 A;  3EPX A;  4WR2 A;  1YOE A;  3MKN A;  3T8I A;  1EZR A;  5TSQ A;  2FF2 A;  4P5F A;  4I75 A;  3MKM A;  4I71 A;  1R4F A;  2MAS A;  3EPW A;  4KPO A;  1KIC A;  2YHG A;  4I70 A;  1Q8F A;  4I73 A;  4KPN A; 
#chains in the Genus database with same CATH homology
 1HOZ A;  4I72 A;  1MAS A;  3B9X A;  1HP0 A;  1KIE A;  3FZ0 A;  2FF1 A;  2C40 A;  3B9G A;  3T8J A;  4I74 A;  3G5I A;  4KL0 A;  3EPX A;  4WR2 A;  1YOE A;  3MKN A;  3T8I A;  1EZR A;  5TSQ A;  2FF2 A;  4P5F A;  4I75 A;  3MKM A;  4I71 A;  1R4F A;  2MAS A;  3EPW A;  4KPO A;  1KIC A;  2YHG A;  4I70 A;  1Q8F A;  4I73 A;  4KPN A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3EPXA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations