3FZ0A

Inosine-guanosine nucleoside hydrolase (ig-nh)
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
356
structure length
327
Chain Sequence
VHRKLIIDTDCGGDDAIAIMLAMTQPDVEVIAITVVWGNVEVNQGMENIGKLLDLYDADIPFFRGAEGPLVGERETVQWGGFGSDGFGDAGFPPSQRVALQPKRHAALEILKILEEAEPSDDVVYQLVALGPLTNVALALRLNPDLFSKLGTDTIPGIVIMNGTSESKGNSNMAAEFNSHCDPEAGVVVLQHKGWKCPVQLVNWEVTVNSPMTWGFYDKLVNRQNKWQEFIEKLFQRLEAFTRVTCVVPDAVAVLVAIRPESVLDSFLTYVTVELHGRETRGATCIDWYGTEQSMAKKGRWRNCNVITKVDNEMFLKALRDIVEYVA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei
molecule keywords Nucleoside hydrolase, putative
total genus 115
structure length 327
sequence length 356
chains with identical sequence B, C, D
ec nomenclature ec 3.2.2.1: Purine nucleosidase.
pdb deposition date 2009-01-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 3fz0A00
1EZRA 4I74A 2MASA 4I70A 4P5FA 1YOEA 3FZ0A 4I75A 3T8JA 4I71A 4KL0A 2FF2A 3MKNA 1R4FA 1MASA 1KIEA 3T8IA 1HOZA 4I72A 1HP0A 1Q8FA 3B9GA 2C40A 3G5IA 4KPOA 4KPNA 1KICA 4WR2A 3EPXA 5TSQA 3B9XA 2YHGA 4I73A 2FF1A 3MKMA 3EPWA
chains in the Genus database with same CATH superfamily
1EZRA 4I74A 2MASA 4I70A 4P5FA 1YOEA 3FZ0A 4I75A 3T8JA 4I71A 4KL0A 2FF2A 3MKNA 1R4FA 1MASA 1KIEA 3T8IA 1HOZA 4I72A 1HP0A 1Q8FA 3B9GA 2C40A 3G5IA 4KPOA 4KPNA 1KICA 4WR2A 3EPXA 5TSQA 3B9XA 2YHGA 4I73A 2FF1A 3MKMA 3EPWA
chains in the Genus database with same CATH topology
1EZRA 4I74A 2MASA 4I70A 4P5FA 1YOEA 3FZ0A 4I75A 3T8JA 4I71A 4KL0A 2FF2A 3MKNA 1R4FA 1MASA 1KIEA 3T8IA 1HOZA 4I72A 1HP0A 1Q8FA 3B9GA 2C40A 3G5IA 4KPOA 4KPNA 1KICA 4WR2A 3EPXA 5TSQA 3B9XA 2YHGA 4I73A 2FF1A 3MKMA 3EPWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EZR A;  4I74 A;  2MAS A;  4I70 A;  4P5F A;  1YOE A;  3FZ0 A;  4I75 A;  3T8J A;  4I71 A;  4KL0 A;  2FF2 A;  3MKN A;  1R4F A;  1MAS A;  1KIE A;  3T8I A;  1HOZ A;  4I72 A;  1HP0 A;  1Q8F A;  3B9G A;  2C40 A;  3G5I A;  4KPO A;  4KPN A;  1KIC A;  4WR2 A;  3EPX A;  5TSQ A;  3B9X A;  2YHG A;  4I73 A;  2FF1 A;  3MKM A;  3EPW A; 
#chains in the Genus database with same CATH topology
 1EZR A;  4I74 A;  2MAS A;  4I70 A;  4P5F A;  1YOE A;  3FZ0 A;  4I75 A;  3T8J A;  4I71 A;  4KL0 A;  2FF2 A;  3MKN A;  1R4F A;  1MAS A;  1KIE A;  3T8I A;  1HOZ A;  4I72 A;  1HP0 A;  1Q8F A;  3B9G A;  2C40 A;  3G5I A;  4KPO A;  4KPN A;  1KIC A;  4WR2 A;  3EPX A;  5TSQ A;  3B9X A;  2YHG A;  4I73 A;  2FF1 A;  3MKM A;  3EPW A; 
#chains in the Genus database with same CATH homology
 1EZR A;  4I74 A;  2MAS A;  4I70 A;  4P5F A;  1YOE A;  3FZ0 A;  4I75 A;  3T8J A;  4I71 A;  4KL0 A;  2FF2 A;  3MKN A;  1R4F A;  1MAS A;  1KIE A;  3T8I A;  1HOZ A;  4I72 A;  1HP0 A;  1Q8F A;  3B9G A;  2C40 A;  3G5I A;  4KPO A;  4KPN A;  1KIC A;  4WR2 A;  3EPX A;  5TSQ A;  3B9X A;  2YHG A;  4I73 A;  2FF1 A;  3MKM A;  3EPW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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