3G5IA

Crystal structure of the e.coli riha pyrimidine nucleosidase bound to a iminoribitol-based inhibitor
Total Genus 100
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
100
sequence length
310
structure length
305
Chain Sequence
ALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the RihA nucleoside hydrolase bound to a competitive inhibitor
rcsb
molecule keywords Pyrimidine-specific ribonucleoside hydrolase rihA
molecule tags Hydrolase
source organism Escherichia coli
total genus 100
structure length 305
sequence length 310
chains with identical sequence B, C, D
ec nomenclature ec 3.2.2.8: Ribosylpyrimidine nucleosidase.
pdb deposition date 2009-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01156 IU_nuc_hydro Inosine-uridine preferring nucleoside hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.245.10 Alpha Beta Alpha-Beta Complex Inosine-uridine Nucleoside N-ribohydrolase; Chain A Ribonucleoside hydrolase-like 3g5iA00
4I74A 3FZ0A 1MASA 4KL0A 4KPOA 4I75A 1YOEA 3EPXA 2FF1A 3T8JA 3B9GA 1HP0A 2MASA 4KPNA 1R4FA 4I72A 3G5IA 3EPWA 4I73A 1Q8FA 3B9XA 1HOZA 4P5FA 4I71A 2C40A 4I70A 1EZRA 2YHGA 5TSQA 2FF2A 3T8IA 3MKNA 4WR2A 3MKMA 1KIEA 1KICA
chains in the Genus database with same CATH superfamily
4I74A 3FZ0A 1MASA 4KL0A 4KPOA 4I75A 1YOEA 3EPXA 2FF1A 3T8JA 3B9GA 1HP0A 2MASA 4KPNA 1R4FA 4I72A 3G5IA 3EPWA 4I73A 1Q8FA 3B9XA 1HOZA 4P5FA 4I71A 2C40A 4I70A 1EZRA 2YHGA 5TSQA 2FF2A 3T8IA 3MKNA 4WR2A 3MKMA 1KIEA 1KICA
chains in the Genus database with same CATH topology
4I74A 3FZ0A 1MASA 4KL0A 4KPOA 4I75A 1YOEA 3EPXA 2FF1A 3T8JA 3B9GA 1HP0A 2MASA 4KPNA 1R4FA 4I72A 3G5IA 3EPWA 4I73A 1Q8FA 3B9XA 1HOZA 4P5FA 4I71A 2C40A 4I70A 1EZRA 2YHGA 5TSQA 2FF2A 3T8IA 3MKNA 4WR2A 3MKMA 1KIEA 1KICA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I74 A;  3FZ0 A;  1MAS A;  4KL0 A;  4KPO A;  4I75 A;  1YOE A;  3EPX A;  2FF1 A;  3T8J A;  3B9G A;  1HP0 A;  2MAS A;  4KPN A;  1R4F A;  4I72 A;  3G5I A;  3EPW A;  4I73 A;  1Q8F A;  3B9X A;  1HOZ A;  4P5F A;  4I71 A;  2C40 A;  4I70 A;  1EZR A;  2YHG A;  5TSQ A;  2FF2 A;  3T8I A;  3MKN A;  4WR2 A;  3MKM A;  1KIE A;  1KIC A; 
#chains in the Genus database with same CATH topology
 4I74 A;  3FZ0 A;  1MAS A;  4KL0 A;  4KPO A;  4I75 A;  1YOE A;  3EPX A;  2FF1 A;  3T8J A;  3B9G A;  1HP0 A;  2MAS A;  4KPN A;  1R4F A;  4I72 A;  3G5I A;  3EPW A;  4I73 A;  1Q8F A;  3B9X A;  1HOZ A;  4P5F A;  4I71 A;  2C40 A;  4I70 A;  1EZR A;  2YHG A;  5TSQ A;  2FF2 A;  3T8I A;  3MKN A;  4WR2 A;  3MKM A;  1KIE A;  1KIC A; 
#chains in the Genus database with same CATH homology
 4I74 A;  3FZ0 A;  1MAS A;  4KL0 A;  4KPO A;  4I75 A;  1YOE A;  3EPX A;  2FF1 A;  3T8J A;  3B9G A;  1HP0 A;  2MAS A;  4KPN A;  1R4F A;  4I72 A;  3G5I A;  3EPW A;  4I73 A;  1Q8F A;  3B9X A;  1HOZ A;  4P5F A;  4I71 A;  2C40 A;  4I70 A;  1EZR A;  2YHG A;  5TSQ A;  2FF2 A;  3T8I A;  3MKN A;  4WR2 A;  3MKM A;  1KIE A;  1KIC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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