3RII | Genus

Total Genus 68

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	68
Knots found	KnotProt 2.0: K -5₂ -3₁ -3₁
sequence length	222
structure length	212
Chain Sequence	GEWCLMESDPGVFTELIKGFGCRGAQVEEIWSLEPENFEKLKPVHGLIFLFKWQPGEEPAGSVVQDSRLDTIFFAKQVINNASATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQAKEEDAFHFVSYVPVNGRLYELDGLREGPIDLGACNQDDWISAVRPVIEKRIQKYSEGEIRFNLMAIVSDR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 212 atoms

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212 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Homo sapiens
publication title	Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme. pubmed doi rcsb
molecule keywords	Ubiquitin carboxyl-terminal hydrolase isozyme L5
total genus	68
structure length	212
sequence length	222
chains with identical sequence	B
other databases	KnotProt 2.0: K -5₂ -3₁ -3₁
ec nomenclature	ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date	2011-04-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01088	Peptidase_C12	Ubiquitin carboxyl-terminal hydrolase, family 1

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.40.532.10	Alpha Beta	3-Layer(aba) Sandwich	Ubiquitin C-terminal Hydrolase UCH-l3	Peptidase C12, ubiquitin carboxyl-terminal hydrolase	3riiA00

4IG7A 3IFWA 4JKJA 2ETLA 2LENA 3KVFA 3IHRA 4UEMA 1CMXA 3A7SA 3KW5A 1UCHA 4I6NA 4DM9A 1XD3A 4UELA 3TB3A 3IRTA 3RISA 3RIIA
chains in the Genus database with same CATH superfamily

4IG7A 3IFWA 4JKJA 2ETLA 2LENA 3KVFA 3IHRA 4UEMA 1CMXA 3A7SA 3KW5A 1UCHA 4I6NA 4DM9A 1XD3A 4UELA 3TB3A 3IRTA 3RISA 3RIIA
chains in the Genus database with same CATH topology

4IG7A 3IFWA 4JKJA 2ETLA 2LENA 3KVFA 3IHRA 4UEMA 1CMXA 3A7SA 3KW5A 1UCHA 4I6NA 4DM9A 1XD3A 4UELA 3TB3A 3IRTA 3RISA 3RIIA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4IG7 A;  3IFW A;  4JKJ A;  2ETL A;  2LEN A;  3KVF A;  3IHR A;  4UEM A;  1CMX A;  3A7S A;  3KW5 A;  1UCH A;  4I6N A;  4DM9 A;  1XD3 A;  4UEL A;  3TB3 A;  3IRT A;  3RIS A;  3RII A; 
#chains in the Genus database with same CATH topology
 4IG7 A;  3IFW A;  4JKJ A;  2ETL A;  2LEN A;  3KVF A;  3IHR A;  4UEM A;  1CMX A;  3A7S A;  3KW5 A;  1UCH A;  4I6N A;  4DM9 A;  1XD3 A;  4UEL A;  3TB3 A;  3IRT A;  3RIS A;  3RII A; 
#chains in the Genus database with same CATH homology
 4IG7 A;  3IFW A;  4JKJ A;  2ETL A;  2LEN A;  3KVF A;  3IHR A;  4UEM A;  1CMX A;  3A7S A;  3KW5 A;  1UCH A;  4I6N A;  4DM9 A;  1XD3 A;  4UEL A;  3TB3 A;  3IRT A;  3RIS A;  3RII A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3RIIA

Total Genus

Knots found

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations