3T8J | Genus

Total Genus 120

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	120
sequence length	311
structure length	311
Chain Sequence	MRHFIIDCDTAEDDVLSLYLLLKNNIDVVAVTIVEGNISYEQEVKNALWALEQVNREIPVYPGANKPLLKNYITVEKVHGKGGIGDVTVEPKRLKAQEKHAALAIIDLANEYAGELEFLAISPLTNLALAYLLDNSIVKKIKKVWVMGGAVFGIGNITPVAEFNIWVDPDAAKIVFNAGFDITMIPWDVIINYPVTDEEWNVIKNMKTRMSELYVSMYLHYRQYSSTVQKINGHPHPDAITTAIAIDGSIATRREKRFVVIDNTDNITRGMTLVDRFDADTSWSDKPNAEIVYEINKKSFMEKIYDLLNWF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__4612975002741555__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__4612975002741555__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/3T8J/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__4612975002741555__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"4612975002741555","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/3T8J/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__4612975002741555__ ready

script 1 started

platformSpeed = 8

Viewer cachePut cache://localLOAD_/file/5d030611bd81710f1c8220a0/pdb.gz

Viewer cachePut https://genus.fuw.edu.pl/file/5d030611bd81710f1c8220a0/pdb.gz

FileManager.getAtomSetCollectionFromFile(/file/5d030611bd81710f1c8220a0/pdb.gz)

loadScript /static/js/j2s/core/corezip.z.js

The Resolver thinks Pdb

loadScript /static/js/j2s/core/corebio.z.js

Time for openFile(/file/5d030611bd81710f1c8220a0/pdb.gz): 290 ms

reading 311 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

311 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 38 ms

Adding embedded #jmolscript: select ({0:310});backbone only;select *;

platformSpeed = 8

cartoonsFancy = true

sheetSmoothing = 1.0

traceAlpha = true

loadScript /static/js/j2s/core/corescriptcmd.z.js

specularPower = 9

ambientPercent = 20

antialiasDisplay = true

Script completed

Jmol script terminated

loadScript /static/js/j2s/J/g3d/HermiteRenderer.js

loadScript /static/js/j2s/J/renderbio/BioMeshRenderer.js

loadScript /static/js/j2s/J/render/MeshRenderer.js

loadScript /static/js/j2s/J/shape/Mesh.js

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	New Determinants in the Catalytic Mechanism of Nucleoside Hydrolases from the Structures of Two Isozymes from Sulfolobus solfataricus. pubmed doi rcsb
molecule keywords	Purine nucleosidase, (IunH-1)
molecule tags	Hydrolase
source organism	Sulfolobus solfataricus
total genus	120
structure length	311
sequence length	311
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2011-08-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	3t8jA00

2C40A 1HOZA 4KPOA 4P5FA 1KICA 3MKMA 3EPXA 2FF2A 3FZ0A 5TSQA 1R4FA 3T8IA 4I72A 4WR2A 2FF1A 3G5IA 3EPWA 1HP0A 3MKNA 4KL0A 1Q8FA 1EZRA 2MASA 4I70A 3B9GA 3T8JA 2YHGA 1KIEA 1MASA 4I71A 3B9XA 4I73A 4KPNA 4I75A 4I74A 1YOEA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2C40 A;  1HOZ A;  4KPO A;  4P5F A;  1KIC A;  3MKM A;  3EPX A;  2FF2 A;  3FZ0 A;  5TSQ A;  1R4F A;  3T8I A;  4I72 A;  4WR2 A;  2FF1 A;  3G5I A;  3EPW A;  1HP0 A;  3MKN A;  4KL0 A;  1Q8F A;  1EZR A;  2MAS A;  4I70 A;  3B9G A;  3T8J A;  2YHG A;  1KIE A;  1MAS A;  4I71 A;  3B9X A;  4I73 A;  4KPN A;  4I75 A;  4I74 A;  1YOE A; 
#chains in the Genus database with same CATH topology
 2C40 A;  1HOZ A;  4KPO A;  4P5F A;  1KIC A;  3MKM A;  3EPX A;  2FF2 A;  3FZ0 A;  5TSQ A;  1R4F A;  3T8I A;  4I72 A;  4WR2 A;  2FF1 A;  3G5I A;  3EPW A;  1HP0 A;  3MKN A;  4KL0 A;  1Q8F A;  1EZR A;  2MAS A;  4I70 A;  3B9G A;  3T8J A;  2YHG A;  1KIE A;  1MAS A;  4I71 A;  3B9X A;  4I73 A;  4KPN A;  4I75 A;  4I74 A;  1YOE A; 
#chains in the Genus database with same CATH homology
 2C40 A;  1HOZ A;  4KPO A;  4P5F A;  1KIC A;  3MKM A;  3EPX A;  2FF2 A;  3FZ0 A;  5TSQ A;  1R4F A;  3T8I A;  4I72 A;  4WR2 A;  2FF1 A;  3G5I A;  3EPW A;  1HP0 A;  3MKN A;  4KL0 A;  1Q8F A;  1EZR A;  2MAS A;  4I70 A;  3B9G A;  3T8J A;  2YHG A;  1KIE A;  1MAS A;  4I71 A;  3B9X A;  4I73 A;  4KPN A;  4I75 A;  4I74 A;  1YOE A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

3T8JA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations