3T8J | Genus

Total Genus 120

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	120
sequence length	311
structure length	311
Chain Sequence	MRHFIIDCDTAEDDVLSLYLLLKNNIDVVAVTIVEGNISYEQEVKNALWALEQVNREIPVYPGANKPLLKNYITVEKVHGKGGIGDVTVEPKRLKAQEKHAALAIIDLANEYAGELEFLAISPLTNLALAYLLDNSIVKKIKKVWVMGGAVFGIGNITPVAEFNIWVDPDAAKIVFNAGFDITMIPWDVIINYPVTDEEWNVIKNMKTRMSELYVSMYLHYRQYSSTVQKINGHPHPDAITTAIAIDGSIATRREKRFVVIDNTDNITRGMTLVDRFDADTSWSDKPNAEIVYEINKKSFMEKIYDLLNWF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	New Determinants in the Catalytic Mechanism of Nucleoside Hydrolases from the Structures of Two Isozymes from Sulfolobus solfataricus. pubmed doi rcsb
molecule keywords	Purine nucleosidase, (IunH-1)
molecule tags	Hydrolase
source organism	Sulfolobus solfataricus
total genus	120
structure length	311
sequence length	311
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2011-08-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	3t8jA00

1KIEA 3MKNA 1HOZA 1R4FA 2YHGA 3T8JA 3MKMA 4I73A 3G5IA 3EPWA 3B9GA 1YOEA 2C40A 3FZ0A 4KPNA 4KPOA 2FF2A 2MASA 1HP0A 3T8IA 3EPXA 2FF1A 4I74A 4I75A 4I72A 4P5FA 1Q8FA 1KICA 4KL0A 3B9XA 4I70A 1MASA 4WR2A 1EZRA 4I71A 5TSQA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1KIE A;  3MKN A;  1HOZ A;  1R4F A;  2YHG A;  3T8J A;  3MKM A;  4I73 A;  3G5I A;  3EPW A;  3B9G A;  1YOE A;  2C40 A;  3FZ0 A;  4KPN A;  4KPO A;  2FF2 A;  2MAS A;  1HP0 A;  3T8I A;  3EPX A;  2FF1 A;  4I74 A;  4I75 A;  4I72 A;  4P5F A;  1Q8F A;  1KIC A;  4KL0 A;  3B9X A;  4I70 A;  1MAS A;  4WR2 A;  1EZR A;  4I71 A;  5TSQ A; 
#chains in the Genus database with same CATH topology
 1KIE A;  3MKN A;  1HOZ A;  1R4F A;  2YHG A;  3T8J A;  3MKM A;  4I73 A;  3G5I A;  3EPW A;  3B9G A;  1YOE A;  2C40 A;  3FZ0 A;  4KPN A;  4KPO A;  2FF2 A;  2MAS A;  1HP0 A;  3T8I A;  3EPX A;  2FF1 A;  4I74 A;  4I75 A;  4I72 A;  4P5F A;  1Q8F A;  1KIC A;  4KL0 A;  3B9X A;  4I70 A;  1MAS A;  4WR2 A;  1EZR A;  4I71 A;  5TSQ A; 
#chains in the Genus database with same CATH homology
 1KIE A;  3MKN A;  1HOZ A;  1R4F A;  2YHG A;  3T8J A;  3MKM A;  4I73 A;  3G5I A;  3EPW A;  3B9G A;  1YOE A;  2C40 A;  3FZ0 A;  4KPN A;  4KPO A;  2FF2 A;  2MAS A;  1HP0 A;  3T8I A;  3EPX A;  2FF1 A;  4I74 A;  4I75 A;  4I72 A;  4P5F A;  1Q8F A;  1KIC A;  4KL0 A;  3B9X A;  4I70 A;  1MAS A;  4WR2 A;  1EZR A;  4I71 A;  5TSQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3T8JA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations