4I6NA

Crystal structure of trichinella spiralis uch37 catalytic domain bound to ubiquitin vinyl methyl ester
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
Knots found
sequence length
229
structure length
219
Chain Sequence
PLGSMAEGNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLDESIEHLKPIHGFIFLFRWLKKEMRKEVDDSPQTCTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDSASRGLCLTNSEKIRAVHNSFGQKLDEEDVFHFVTYVPVNDGVYELDGLRAAPLRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C-Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
pubmed doi rcsb
molecule tags Hydrolase/signaling protein
source organism Trichinella spiralis
molecule keywords Ubiquitin carboxyl-hydrolase
total genus 64
structure length 219
sequence length 229
chains with identical sequence C
other databases KnotProt 2.0: K -52 -31 -31
ec nomenclature
pdb deposition date 2012-11-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 4i6nA00
3KVFA 4JKJA 1XD3A 3KW5A 1UCHA 3TB3A 3RISA 3IFWA 2ETLA 1CMXA 4I6NA 3IHRA 4UEMA 4UELA 4DM9A 3IRTA 4IG7A 3RIIA 3A7SA 2LENA
chains in the Genus database with same CATH superfamily
3KVFA 4JKJA 1XD3A 3KW5A 1UCHA 3TB3A 3RISA 3IFWA 2ETLA 1CMXA 4I6NA 3IHRA 4UEMA 4UELA 4DM9A 3IRTA 4IG7A 3RIIA 3A7SA 2LENA
chains in the Genus database with same CATH topology
3KVFA 4JKJA 1XD3A 3KW5A 1UCHA 3TB3A 3RISA 3IFWA 2ETLA 1CMXA 4I6NA 3IHRA 4UEMA 4UELA 4DM9A 3IRTA 4IG7A 3RIIA 3A7SA 2LENA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KVF A;  4JKJ A;  1XD3 A;  3KW5 A;  1UCH A;  3TB3 A;  3RIS A;  3IFW A;  2ETL A;  1CMX A;  4I6N A;  3IHR A;  4UEM A;  4UEL A;  4DM9 A;  3IRT A;  4IG7 A;  3RII A;  3A7S A;  2LEN A; 
#chains in the Genus database with same CATH topology
 3KVF A;  4JKJ A;  1XD3 A;  3KW5 A;  1UCH A;  3TB3 A;  3RIS A;  3IFW A;  2ETL A;  1CMX A;  4I6N A;  3IHR A;  4UEM A;  4UEL A;  4DM9 A;  3IRT A;  4IG7 A;  3RII A;  3A7S A;  2LEN A; 
#chains in the Genus database with same CATH homology
 3KVF A;  4JKJ A;  1XD3 A;  3KW5 A;  1UCH A;  3TB3 A;  3RIS A;  3IFW A;  2ETL A;  1CMX A;  4I6N A;  3IHR A;  4UEM A;  4UEL A;  4DM9 A;  3IRT A;  4IG7 A;  3RII A;  3A7S A;  2LEN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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