4I70 | Genus

Total Genus 123

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	123
sequence length	327
structure length	316
Chain Sequence	MAKTVILDHDGNKDDFVAMILLLSNPKKVNLIGCICTDADCFVENGFDVTGKIMCAMHRLIKTPLFPIGKSTATAVNAFPTEWRFSAKNLDDMPFLNIVEDVALWEKLKPENEAHNGQQLLADLVMKSKEKVTVCVTGPLSNMAWCIEKYGEAFTSKVEECVIMGGAVDVGGNVFLPTTDGSAEWNIYWDPPAAKKVLCCPNIRCVLFSLDATNTVPVRSVDVKGFGAQNQYLLSQMVGTMWAMAYYAWDALTAAYILEPTIATLEPVALDVDVSKGKSEGRTPRASGEGKPCVHVARNPSKQMFHDLVFASTRVC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 316 atoms

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316 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor pubmed doi rcsb
molecule keywords	Inosine-adenosine-guanosine-nucleoside hydrolase
molecule tags	Hydrolase
source organism	Trypanosoma brucei brucei
total genus	123
structure length	316
sequence length	327
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2012-11-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	4i70A00

4I75A 1R4FA 1KICA 2FF2A 1HOZA 3T8JA 4KL0A 4I74A 4I72A 4KPOA 3B9GA 3B9XA 2C40A 2FF1A 4I71A 2YHGA 3T8IA 1HP0A 1EZRA 1MASA 4I70A 1Q8FA 4KPNA 3MKMA 3EPXA 4WR2A 3MKNA 4P5FA 2MASA 5TSQA 1KIEA 3FZ0A 3G5IA 4I73A 3EPWA 1YOEA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4I75 A;  1R4F A;  1KIC A;  2FF2 A;  1HOZ A;  3T8J A;  4KL0 A;  4I74 A;  4I72 A;  4KPO A;  3B9G A;  3B9X A;  2C40 A;  2FF1 A;  4I71 A;  2YHG A;  3T8I A;  1HP0 A;  1EZR A;  1MAS A;  4I70 A;  1Q8F A;  4KPN A;  3MKM A;  3EPX A;  4WR2 A;  3MKN A;  4P5F A;  2MAS A;  5TSQ A;  1KIE A;  3FZ0 A;  3G5I A;  4I73 A;  3EPW A;  1YOE A; 
#chains in the Genus database with same CATH topology
 4I75 A;  1R4F A;  1KIC A;  2FF2 A;  1HOZ A;  3T8J A;  4KL0 A;  4I74 A;  4I72 A;  4KPO A;  3B9G A;  3B9X A;  2C40 A;  2FF1 A;  4I71 A;  2YHG A;  3T8I A;  1HP0 A;  1EZR A;  1MAS A;  4I70 A;  1Q8F A;  4KPN A;  3MKM A;  3EPX A;  4WR2 A;  3MKN A;  4P5F A;  2MAS A;  5TSQ A;  1KIE A;  3FZ0 A;  3G5I A;  4I73 A;  3EPW A;  1YOE A; 
#chains in the Genus database with same CATH homology
 4I75 A;  1R4F A;  1KIC A;  2FF2 A;  1HOZ A;  3T8J A;  4KL0 A;  4I74 A;  4I72 A;  4KPO A;  3B9G A;  3B9X A;  2C40 A;  2FF1 A;  4I71 A;  2YHG A;  3T8I A;  1HP0 A;  1EZR A;  1MAS A;  4I70 A;  1Q8F A;  4KPN A;  3MKM A;  3EPX A;  4WR2 A;  3MKN A;  4P5F A;  2MAS A;  5TSQ A;  1KIE A;  3FZ0 A;  3G5I A;  4I73 A;  3EPW A;  1YOE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4I70A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations