4I72 | Genus

Total Genus 132

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	132
sequence length	330
structure length	328
Chain Sequence	GSHMAKTVILDHDGNKDDFVAMILLLSNPKKVNLIGCICTDADCFVENGFDVTGKIMCAMHRLIKTPLFPIGKSTATAVNAFPTEWRFSAKNLDDMPFLNIVEDVALWEKLKPENEAHNGQQLLADLVMKSKEKVTVCVTGPLSNMAWCIEKYGEAFTSKVEECVIMGGAVDVGGNVFLPTTDGSAEWNIYWDPPAAKKVLCCPNIRCVLFSLDATNTVPVRSVDVKGFGAQNQYLLSQMVGTMWAMSTHEEILRDGDAYYAWDALTAAYILEPTIATLEPVALDVDVSKGKSEGRTPRASGKPCVHVARNPSKQMFHDLVFASTRVC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 328 atoms

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328 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor pubmed doi rcsb
molecule keywords	Inosine-adenosine-guanosine-nucleoside hydrolase
molecule tags	Hydrolase/hydrolase inhibitor
source organism	Trypanosoma brucei brucei
total genus	132
structure length	328
sequence length	330
chains with identical sequence	B
ec nomenclature	ec 3.2.2.1: Purine nucleosidase.
pdb deposition date	2012-11-30

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01156	IU_nuc_hydro	Inosine-uridine preferring nucleoside hydrolase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase; Chain A	Ribonucleoside hydrolase-like	4i72A00

2MASA 4I75A 2FF2A 4KPOA 4I70A 3EPXA 4I71A 5TSQA 3G5IA 2FF1A 4I72A 2C40A 3FZ0A 4P5FA 1HOZA 3EPWA 1R4FA 1MASA 1HP0A 3B9XA 2YHGA 3MKNA 1EZRA 4WR2A 3B9GA 3T8JA 1KIEA 4I74A 3T8IA 1Q8FA 3MKMA 1YOEA 1KICA 4KL0A 4KPNA 4I73A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2MAS A;  4I75 A;  2FF2 A;  4KPO A;  4I70 A;  3EPX A;  4I71 A;  5TSQ A;  3G5I A;  2FF1 A;  4I72 A;  2C40 A;  3FZ0 A;  4P5F A;  1HOZ A;  3EPW A;  1R4F A;  1MAS A;  1HP0 A;  3B9X A;  2YHG A;  3MKN A;  1EZR A;  4WR2 A;  3B9G A;  3T8J A;  1KIE A;  4I74 A;  3T8I A;  1Q8F A;  3MKM A;  1YOE A;  1KIC A;  4KL0 A;  4KPN A;  4I73 A; 
#chains in the Genus database with same CATH topology
 2MAS A;  4I75 A;  2FF2 A;  4KPO A;  4I70 A;  3EPX A;  4I71 A;  5TSQ A;  3G5I A;  2FF1 A;  4I72 A;  2C40 A;  3FZ0 A;  4P5F A;  1HOZ A;  3EPW A;  1R4F A;  1MAS A;  1HP0 A;  3B9X A;  2YHG A;  3MKN A;  1EZR A;  4WR2 A;  3B9G A;  3T8J A;  1KIE A;  4I74 A;  3T8I A;  1Q8F A;  3MKM A;  1YOE A;  1KIC A;  4KL0 A;  4KPN A;  4I73 A; 
#chains in the Genus database with same CATH homology
 2MAS A;  4I75 A;  2FF2 A;  4KPO A;  4I70 A;  3EPX A;  4I71 A;  5TSQ A;  3G5I A;  2FF1 A;  4I72 A;  2C40 A;  3FZ0 A;  4P5F A;  1HOZ A;  3EPW A;  1R4F A;  1MAS A;  1HP0 A;  3B9X A;  2YHG A;  3MKN A;  1EZR A;  4WR2 A;  3B9G A;  3T8J A;  1KIE A;  4I74 A;  3T8I A;  1Q8F A;  3MKM A;  1YOE A;  1KIC A;  4KL0 A;  4KPN A;  4I73 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4I72A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations