The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
129
|
sequence length |
330
|
structure length |
327
|
Chain Sequence |
GSHMAKTVILDHDGNKDDFVAMILLLSNPKKVNLIGCICTDADCFVENGFDVTGKIMCAMHRLIKTPLFPIGKSTATAVNAFPTEWRFSAKNLDDMPFLNIVEDVALWEKLKPENEAHNGQQLLADLVMKSKEKVTVCVTGPLSNMAWCIEKYGEAFTSKVEECVIMGGAVDVGGNVFLPTTDGSAEWNIYWDPPAAKKVLCCPNIRCVLFSLDATNTVPVRSVDVKGFGAQNQYLLSQMVGTMWAMSTHEEILRDGDAYYAWDALTAAYILEPTIATLEPVALDVDVSKGKSEGRTPRASGPCVHVARNPSKQMFHDLVFASTRVC
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor
pubmed doi rcsb |
| molecule tags |
Hydrolase/hydrolase inhibitor
|
| source organism |
Trypanosoma brucei brucei
|
| molecule keywords |
Inosine-adenosine-guanosine-nucleoside hydrolase
|
| total genus |
129
|
| structure length |
327
|
| sequence length |
330
|
| ec nomenclature |
ec
3.2.2.1: Purine nucleosidase. |
| pdb deposition date | 2012-11-30 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF01156 | IU_nuc_hydro | Inosine-uridine preferring nucleoside hydrolase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | Alpha-Beta Complex | Inosine-uridine Nucleoside N-ribohydrolase; Chain A | Ribonucleoside hydrolase-like |
#chains in the Genus database with same CATH superfamily 2FF1 A; 1KIE A; 3EPX A; 1EZR A; 3MKM A; 4I75 A; 1MAS A; 4I70 A; 2YHG A; 3B9X A; 1KIC A; 2C40 A; 4I71 A; 4I74 A; 3EPW A; 1Q8F A; 1YOE A; 4KPO A; 2FF2 A; 1R4F A; 4I73 A; 3B9G A; 5TSQ A; 3T8I A; 1HOZ A; 2MAS A; 3FZ0 A; 4KPN A; 4I72 A; 3T8J A; 3G5I A; 1HP0 A; 4KL0 A; 4WR2 A; 3MKN A; 4P5F A; #chains in the Genus database with same CATH topology 2FF1 A; 1KIE A; 3EPX A; 1EZR A; 3MKM A; 4I75 A; 1MAS A; 4I70 A; 2YHG A; 3B9X A; 1KIC A; 2C40 A; 4I71 A; 4I74 A; 3EPW A; 1Q8F A; 1YOE A; 4KPO A; 2FF2 A; 1R4F A; 4I73 A; 3B9G A; 5TSQ A; 3T8I A; 1HOZ A; 2MAS A; 3FZ0 A; 4KPN A; 4I72 A; 3T8J A; 3G5I A; 1HP0 A; 4KL0 A; 4WR2 A; 3MKN A; 4P5F A; #chains in the Genus database with same CATH homology 2FF1 A; 1KIE A; 3EPX A; 1EZR A; 3MKM A; 4I75 A; 1MAS A; 4I70 A; 2YHG A; 3B9X A; 1KIC A; 2C40 A; 4I71 A; 4I74 A; 3EPW A; 1Q8F A; 1YOE A; 4KPO A; 2FF2 A; 1R4F A; 4I73 A; 3B9G A; 5TSQ A; 3T8I A; 1HOZ A; 2MAS A; 3FZ0 A; 4KPN A; 4I72 A; 3T8J A; 3G5I A; 1HP0 A; 4KL0 A; 4WR2 A; 3MKN A; 4P5F A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
