4IG7A

Crystal structure of trichinella spiralis uch37 bound to ubiquitin vinyl methyl ester
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
Knots found
sequence length
260
structure length
231
Chain Sequence
GNWCLIESDPGIFTEMIHGFGCTGLQVEELVVLDESIEHLKPIHGFIFLFRWLKTDVYFSQQVIQNACASQALINLLLNCDHPDVDLGPTLKEFKDFTYDLDSASRGLCLTNSEKIRAVHNSFGEDVFHFVTYVPVNDGVYELDGLRAAPLRLGTVASDGDWTEVAIKAIKEKIKNYGESEVRFNLMAVISDQKLKYEREMEKFAQAGDSAEVDRLVALIAAEDAKRERYA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C‑Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
pubmed doi rcsb
molecule keywords Ubiquitin C-terminal hydrolase 37
molecule tags Hydrolase/signaling protein
source organism Trichinella spiralis
total genus 79
structure length 231
sequence length 260
other databases KnotProt 2.0: K -52 -31 -31
ec nomenclature
pdb deposition date 2012-12-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.532.10 Alpha Beta 3-Layer(aba) Sandwich Ubiquitin C-terminal Hydrolase UCH-l3 Peptidase C12, ubiquitin carboxyl-terminal hydrolase 4ig7A00
4I6NA 1CMXA 4JKJA 1XD3A 3A7SA 2LENA 1UCHA 3RIIA 3RISA 2ETLA 3IHRA 3KVFA 4UEMA 4IG7A 3IFWA 3TB3A 4DM9A 3KW5A 3IRTA 4UELA
chains in the Genus database with same CATH superfamily
4I6NA 1CMXA 4JKJA 1XD3A 3A7SA 2LENA 1UCHA 3RIIA 3RISA 2ETLA 3IHRA 3KVFA 4UEMA 4IG7A 3IFWA 3TB3A 4DM9A 3KW5A 3IRTA 4UELA
chains in the Genus database with same CATH topology
4I6NA 1CMXA 4JKJA 1XD3A 3A7SA 2LENA 1UCHA 3RIIA 3RISA 2ETLA 3IHRA 3KVFA 4UEMA 4IG7A 3IFWA 3TB3A 4DM9A 3KW5A 3IRTA 4UELA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4I6N A;  1CMX A;  4JKJ A;  1XD3 A;  3A7S A;  2LEN A;  1UCH A;  3RII A;  3RIS A;  2ETL A;  3IHR A;  3KVF A;  4UEM A;  4IG7 A;  3IFW A;  3TB3 A;  4DM9 A;  3KW5 A;  3IRT A;  4UEL A; 
#chains in the Genus database with same CATH topology
 4I6N A;  1CMX A;  4JKJ A;  1XD3 A;  3A7S A;  2LEN A;  1UCH A;  3RII A;  3RIS A;  2ETL A;  3IHR A;  3KVF A;  4UEM A;  4IG7 A;  3IFW A;  3TB3 A;  4DM9 A;  3KW5 A;  3IRT A;  4UEL A; 
#chains in the Genus database with same CATH homology
 4I6N A;  1CMX A;  4JKJ A;  1XD3 A;  3A7S A;  2LEN A;  1UCH A;  3RII A;  3RIS A;  2ETL A;  3IHR A;  3KVF A;  4UEM A;  4IG7 A;  3IFW A;  3TB3 A;  4DM9 A;  3KW5 A;  3IRT A;  4UEL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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