3ANZA

Crystal structure of alpha-hemolysin
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
295
structure length
295
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Alpha-hemolysin
publication title 2-Methyl-2,4-pentanediol induces spontaneous assembly of staphylococcal alpha-hemolysin into heptameric pore structure
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 63
structure length 295
sequence length 295
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b
ec nomenclature
pdb deposition date 2010-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3anzA00
4IYAA 3M4EA 4P1YA 3B07A 4TW1B 5K59A 3ROHA 4H56A 2QK7A 2YGTA 3ANZA 4IYTA 4YHDA 1LKFA 3O44A 3M3RA 4IZLA 5K59C 2LKFA 4P1XB 4TW1A 3LKFA 4J0OA 4P24A 4Q7GA 1T5RA 3M4DA 4IYCA 4IDJA 4U6VA 7AHLA 3B07B 4P1XA 4P1YB 1PVLA 3M2LA 2QK7B 4I0NA
chains in the Genus database with same CATH superfamily
4IYAA 3M4EA 4P1YA 3B07A 1XEZA 4TW1B 5K59A 3ROHA 4H56A 2QK7A 2YGTA 3ANZA 4IYTA 4YHDA 1LKFA 3O44A 3M3RA 4IZLA 5K59C 2LKFA 4P1XB 4TW1A 3LKFA 4J0OA 4P24A 4Q7GA 1T5RA 3M4DA 4IYCA 4IDJA 4U6VA 7AHLA 3B07B 4P1XA 4P1YB 1PVLA 3M2LA 2QK7B 4I0NA
chains in the Genus database with same CATH topology
4IYAA 3M4EA 4P1YA 3B07A 4TW1B 5K59A 3ROHA 4H56A 2QK7A 2YGTA 3ANZA 4IYTA 4YHDA 1LKFA 3O44A 3M3RA 4IZLA 5K59C 2LKFA 4P1XB 4TW1A 3LKFA 4J0OA 4P24A 4Q7GA 1T5RA 3M4DA 4IYCA 4IDJA 4U6VA 7AHLA 3B07B 4P1XA 4P1YB 1PVLA 3M2LA 2QK7B 4I0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYA A;  3M4E A;  4P1Y A;  3B07 A;  4TW1 B;  5K59 A;  3ROH A;  4H56 A;  2QK7 A;  2YGT A;  3ANZ A;  4IYT A;  4YHD A;  1LKF A;  3O44 A;  3M3R A;  4IZL A;  5K59 C;  2LKF A;  4P1X B;  4TW1 A;  3LKF A;  4J0O A;  4P24 A;  4Q7G A;  1T5R A;  3M4D A;  4IYC A;  4IDJ A;  4U6V A;  7AHL A;  3B07 B;  4P1X A;  4P1Y B;  1PVL A;  3M2L A;  2QK7 B;  4I0N A; 
#chains in the Genus database with same CATH topology
 4IYA A;  3M4E A;  4P1Y A;  3B07 A;  1XEZ A;  4TW1 B;  5K59 A;  3ROH A;  4H56 A;  2QK7 A;  2YGT A;  3ANZ A;  4IYT A;  4YHD A;  1LKF A;  3O44 A;  3M3R A;  4IZL A;  5K59 C;  2LKF A;  4P1X B;  4TW1 A;  3LKF A;  4J0O A;  4P24 A;  4Q7G A;  1T5R A;  3M4D A;  4IYC A;  4IDJ A;  4U6V A;  7AHL A;  3B07 B;  4P1X A;  4P1Y B;  1PVL A;  3M2L A;  2QK7 B;  4I0N A; 
#chains in the Genus database with same CATH homology
 4IYA A;  3M4E A;  4P1Y A;  3B07 A;  4TW1 B;  5K59 A;  3ROH A;  4H56 A;  2QK7 A;  2YGT A;  3ANZ A;  4IYT A;  4YHD A;  1LKF A;  3O44 A;  3M3R A;  4IZL A;  5K59 C;  2LKF A;  4P1X B;  4TW1 A;  3LKF A;  4J0O A;  4P24 A;  4Q7G A;  1T5R A;  3M4D A;  4IYC A;  4IDJ A;  4U6V A;  7AHL A;  3B07 B;  4P1X A;  4P1Y B;  1PVL A;  3M2L A;  2QK7 B;  4I0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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