7AHLA

Alpha-hemolysin from staphylococcus aureus
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cytolytic protein
molecule keywords ALPHA-HEMOLYSIN
publication title Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore.
pubmed doi rcsb
total genus 54
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 1996-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 7ahlA00
4U6VA 1T5RA 4IYTA 5K59A 4P24A 7AHLA 5K59C 3O44A 3LKFA 3M3RA 4I0NA 4J0OA 4Q7GA 4P1XB 2YGTA 3ANZA 3M2LA 1LKFA 4IDJA 4P1XA 4YHDA 4IYAA 1PVLA 4P1YB 4P1YA 3B07B 4H56A 3M4EA 4IYCA 4IZLA 4TW1B 2QK7B 3B07A 4TW1A 2LKFA 3ROHA 2QK7A 3M4DA
chains in the Genus database with same CATH superfamily
4U6VA 1T5RA 4IYTA 5K59A 4P24A 7AHLA 5K59C 3O44A 3LKFA 3M3RA 4I0NA 4J0OA 4Q7GA 4P1XB 2YGTA 3ANZA 3M2LA 1LKFA 4IDJA 4P1XA 4YHDA 4IYAA 1PVLA 4P1YB 1XEZA 4P1YA 3B07B 4H56A 3M4EA 4IYCA 4IZLA 4TW1B 2QK7B 3B07A 4TW1A 2LKFA 3ROHA 2QK7A 3M4DA
chains in the Genus database with same CATH topology
4U6VA 1T5RA 4IYTA 5K59A 4P24A 7AHLA 5K59C 3O44A 3LKFA 3M3RA 4I0NA 4J0OA 4Q7GA 4P1XB 2YGTA 3ANZA 3M2LA 1LKFA 4IDJA 4P1XA 4YHDA 4IYAA 1PVLA 4P1YB 4P1YA 3B07B 4H56A 3M4EA 4IYCA 4IZLA 4TW1B 2QK7B 3B07A 4TW1A 2LKFA 3ROHA 2QK7A 3M4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6V A;  1T5R A;  4IYT A;  5K59 A;  4P24 A;  7AHL A;  5K59 C;  3O44 A;  3LKF A;  3M3R A;  4I0N A;  4J0O A;  4Q7G A;  4P1X B;  2YGT A;  3ANZ A;  3M2L A;  1LKF A;  4IDJ A;  4P1X A;  4YHD A;  4IYA A;  1PVL A;  4P1Y B;  4P1Y A;  3B07 B;  4H56 A;  3M4E A;  4IYC A;  4IZL A;  4TW1 B;  2QK7 B;  3B07 A;  4TW1 A;  2LKF A;  3ROH A;  2QK7 A;  3M4D A; 
#chains in the Genus database with same CATH topology
 4U6V A;  1T5R A;  4IYT A;  5K59 A;  4P24 A;  7AHL A;  5K59 C;  3O44 A;  3LKF A;  3M3R A;  4I0N A;  4J0O A;  4Q7G A;  4P1X B;  2YGT A;  3ANZ A;  3M2L A;  1LKF A;  4IDJ A;  4P1X A;  4YHD A;  4IYA A;  1PVL A;  4P1Y B;  1XEZ A;  4P1Y A;  3B07 B;  4H56 A;  3M4E A;  4IYC A;  4IZL A;  4TW1 B;  2QK7 B;  3B07 A;  4TW1 A;  2LKF A;  3ROH A;  2QK7 A;  3M4D A; 
#chains in the Genus database with same CATH homology
 4U6V A;  1T5R A;  4IYT A;  5K59 A;  4P24 A;  7AHL A;  5K59 C;  3O44 A;  3LKF A;  3M3R A;  4I0N A;  4J0O A;  4Q7G A;  4P1X B;  2YGT A;  3ANZ A;  3M2L A;  1LKF A;  4IDJ A;  4P1X A;  4YHD A;  4IYA A;  1PVL A;  4P1Y B;  4P1Y A;  3B07 B;  4H56 A;  3M4E A;  4IYC A;  4IZL A;  4TW1 B;  2QK7 B;  3B07 A;  4TW1 A;  2LKF A;  3ROH A;  2QK7 A;  3M4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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