4YHDA

Staphylococcal alpha-hemolysin h35a mutant monomer
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
290
structure length
281
Chain Sequence
INIKTGTTDIGSNTTVKTGDLVTYDKENGMAKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Alpha-hemolysin
publication title Structural basis for pore-forming mechanism of staphylococcal alpha-hemolysin
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 64
structure length 281
sequence length 290
chains with identical sequence B, C, D, E, G
ec nomenclature
pdb deposition date 2015-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4yhdA00
5K59A 3LKFA 1T5RA 2LKFA 4P1YB 4IYAA 2YGTA 4IZLA 4TW1A 4TW1B 4IDJA 4J0OA 4I0NA 4U6VA 3ROHA 4YHDA 5K59C 3M2LA 2QK7A 3M4DA 4IYTA 3M4EA 2QK7B 4P1XA 4P1XB 4Q7GA 3ANZA 1PVLA 4P24A 3M3RA 3O44A 4H56A 3B07A 4IYCA 3B07B 1LKFA 4P1YA 7AHLA
chains in the Genus database with same CATH superfamily
5K59A 3LKFA 1T5RA 2LKFA 4P1YB 4IYAA 2YGTA 4IZLA 4TW1A 4TW1B 4IDJA 4J0OA 4I0NA 4U6VA 3ROHA 4YHDA 5K59C 3M2LA 2QK7A 3M4DA 4IYTA 3M4EA 2QK7B 4P1XA 4P1XB 4Q7GA 3ANZA 1PVLA 4P24A 1XEZA 3M3RA 3O44A 4H56A 3B07A 4IYCA 3B07B 1LKFA 4P1YA 7AHLA
chains in the Genus database with same CATH topology
5K59A 3LKFA 1T5RA 2LKFA 4P1YB 4IYAA 2YGTA 4IZLA 4TW1A 4TW1B 4IDJA 4J0OA 4I0NA 4U6VA 3ROHA 4YHDA 5K59C 3M2LA 2QK7A 3M4DA 4IYTA 3M4EA 2QK7B 4P1XA 4P1XB 4Q7GA 3ANZA 1PVLA 4P24A 3M3RA 3O44A 4H56A 3B07A 4IYCA 3B07B 1LKFA 4P1YA 7AHLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5K59 A;  3LKF A;  1T5R A;  2LKF A;  4P1Y B;  4IYA A;  2YGT A;  4IZL A;  4TW1 A;  4TW1 B;  4IDJ A;  4J0O A;  4I0N A;  4U6V A;  3ROH A;  4YHD A;  5K59 C;  3M2L A;  2QK7 A;  3M4D A;  4IYT A;  3M4E A;  2QK7 B;  4P1X A;  4P1X B;  4Q7G A;  3ANZ A;  1PVL A;  4P24 A;  3M3R A;  3O44 A;  4H56 A;  3B07 A;  4IYC A;  3B07 B;  1LKF A;  4P1Y A;  7AHL A; 
#chains in the Genus database with same CATH topology
 5K59 A;  3LKF A;  1T5R A;  2LKF A;  4P1Y B;  4IYA A;  2YGT A;  4IZL A;  4TW1 A;  4TW1 B;  4IDJ A;  4J0O A;  4I0N A;  4U6V A;  3ROH A;  4YHD A;  5K59 C;  3M2L A;  2QK7 A;  3M4D A;  4IYT A;  3M4E A;  2QK7 B;  4P1X A;  4P1X B;  4Q7G A;  3ANZ A;  1PVL A;  4P24 A;  1XEZ A;  3M3R A;  3O44 A;  4H56 A;  3B07 A;  4IYC A;  3B07 B;  1LKF A;  4P1Y A;  7AHL A; 
#chains in the Genus database with same CATH homology
 5K59 A;  3LKF A;  1T5R A;  2LKF A;  4P1Y B;  4IYA A;  2YGT A;  4IZL A;  4TW1 A;  4TW1 B;  4IDJ A;  4J0O A;  4I0N A;  4U6V A;  3ROH A;  4YHD A;  5K59 C;  3M2L A;  2QK7 A;  3M4D A;  4IYT A;  3M4E A;  2QK7 B;  4P1X A;  4P1X B;  4Q7G A;  3ANZ A;  1PVL A;  4P24 A;  3M3R A;  3O44 A;  4H56 A;  3B07 A;  4IYC A;  3B07 B;  1LKF A;  4P1Y A;  7AHL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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