4IDJA

S.aureus a-hemolysin monomer in complex with fab
Total Genus 63
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
287
structure length
276
Chain Sequence
IKTGTTDIGSNTTVKTGDLVTYDKENGMLKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Immune system
molecule keywords Alpha-hemolysin
publication title Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus alpha-Hemolysin.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 63
structure length 276
sequence length 287
ec nomenclature
pdb deposition date 2012-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4idjA00
3M3RA 3O44A 2QK7A 2YGTA 4TW1B 1LKFA 4Q7GA 3ROHA 4P1YA 3B07B 4I0NA 4IDJA 4IZLA 3M2LA 4IYCA 4IYAA 4P1XB 4YHDA 3M4DA 2QK7B 3ANZA 4TW1A 4H56A 3LKFA 1PVLA 4U6VA 3M4EA 4J0OA 4P1YB 2LKFA 5K59A 4P24A 1T5RA 3B07A 4P1XA 4IYTA 7AHLA 5K59C
chains in the Genus database with same CATH superfamily
3M3RA 3O44A 2QK7A 2YGTA 4TW1B 1LKFA 4Q7GA 3ROHA 4P1YA 3B07B 4I0NA 4IDJA 4IZLA 3M2LA 4IYCA 4IYAA 4P1XB 4YHDA 3M4DA 2QK7B 3ANZA 4TW1A 4H56A 3LKFA 1PVLA 4U6VA 3M4EA 4J0OA 4P1YB 2LKFA 5K59A 4P24A 1T5RA 3B07A 1XEZA 4IYTA 4P1XA 7AHLA 5K59C
chains in the Genus database with same CATH topology
3M3RA 3O44A 2QK7A 2YGTA 4TW1B 1LKFA 4Q7GA 3ROHA 4P1YA 3B07B 4I0NA 4IDJA 4IZLA 3M2LA 4IYCA 4IYAA 4P1XB 4YHDA 3M4DA 2QK7B 3ANZA 4TW1A 4H56A 3LKFA 1PVLA 4U6VA 3M4EA 4J0OA 4P1YB 2LKFA 5K59A 4P24A 1T5RA 3B07A 4P1XA 4IYTA 7AHLA 5K59C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M3R A;  3O44 A;  2QK7 A;  2YGT A;  4TW1 B;  1LKF A;  4Q7G A;  3ROH A;  4P1Y A;  3B07 B;  4I0N A;  4IDJ A;  4IZL A;  3M2L A;  4IYC A;  4IYA A;  4P1X B;  4YHD A;  3M4D A;  2QK7 B;  3ANZ A;  4TW1 A;  4H56 A;  3LKF A;  1PVL A;  4U6V A;  3M4E A;  4J0O A;  4P1Y B;  2LKF A;  5K59 A;  4P24 A;  1T5R A;  3B07 A;  4P1X A;  4IYT A;  7AHL A;  5K59 C; 
#chains in the Genus database with same CATH topology
 3M3R A;  3O44 A;  2QK7 A;  2YGT A;  4TW1 B;  1LKF A;  4Q7G A;  3ROH A;  4P1Y A;  3B07 B;  4I0N A;  4IDJ A;  4IZL A;  3M2L A;  4IYC A;  4IYA A;  4P1X B;  4YHD A;  3M4D A;  2QK7 B;  3ANZ A;  4TW1 A;  4H56 A;  3LKF A;  1PVL A;  4U6V A;  3M4E A;  4J0O A;  4P1Y B;  2LKF A;  5K59 A;  4P24 A;  1T5R A;  3B07 A;  1XEZ A;  4IYT A;  4P1X A;  7AHL A;  5K59 C; 
#chains in the Genus database with same CATH homology
 3M3R A;  3O44 A;  2QK7 A;  2YGT A;  4TW1 B;  1LKF A;  4Q7G A;  3ROH A;  4P1Y A;  3B07 B;  4I0N A;  4IDJ A;  4IZL A;  3M2L A;  4IYC A;  4IYA A;  4P1X B;  4YHD A;  3M4D A;  2QK7 B;  3ANZ A;  4TW1 A;  4H56 A;  3LKF A;  1PVL A;  4U6V A;  3M4E A;  4J0O A;  4P1Y B;  2LKF A;  5K59 A;  4P24 A;  1T5R A;  3B07 A;  4P1X A;  4IYT A;  7AHL A;  5K59 C; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...