4TW1A

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
290
structure length
281
Chain Sequence
GDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Possible leukocidin subunit
publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 59
structure length 281
sequence length 290
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1A00
4IYAA 4U6VA 4TW1A 4Q7GA 4P1YA 4P1XA 3M3RA 3B07B 5K59A 2QK7B 1PVLA 3ANZA 3O44A 5K59C 3M4DA 4YHDA 4IDJA 3LKFA 3ROHA 3M2LA 4J0OA 4IYTA 4P24A 2LKFA 3B07A 4IZLA 2QK7A 4TW1B 7AHLA 4H56A 4IYCA 3M4EA 4P1YB 1LKFA 4P1XB 4I0NA 2YGTA 1T5RA
chains in the Genus database with same CATH superfamily
4IYAA 4U6VA 4TW1A 4Q7GA 1XEZA 4P1YA 4P1XA 3M3RA 3B07B 5K59A 1PVLA 2QK7B 3ANZA 3O44A 5K59C 3M4DA 4YHDA 3LKFA 4IDJA 3ROHA 3M2LA 4J0OA 4IYTA 4P24A 2LKFA 3B07A 4IZLA 2QK7A 4TW1B 7AHLA 4H56A 4IYCA 3M4EA 4P1YB 1LKFA 4P1XB 4I0NA 2YGTA 1T5RA
chains in the Genus database with same CATH topology
4IYAA 4U6VA 4TW1A 4Q7GA 4P1YA 4P1XA 3M3RA 3B07B 5K59A 2QK7B 1PVLA 3ANZA 3O44A 5K59C 3M4DA 4YHDA 4IDJA 3LKFA 3ROHA 3M2LA 4J0OA 4IYTA 4P24A 2LKFA 3B07A 4IZLA 2QK7A 4TW1B 7AHLA 4H56A 4IYCA 3M4EA 4P1YB 1LKFA 4P1XB 4I0NA 2YGTA 1T5RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYA A;  4U6V A;  4TW1 A;  4Q7G A;  4P1Y A;  4P1X A;  3M3R A;  3B07 B;  5K59 A;  2QK7 B;  1PVL A;  3ANZ A;  3O44 A;  5K59 C;  3M4D A;  4YHD A;  4IDJ A;  3LKF A;  3ROH A;  3M2L A;  4J0O A;  4IYT A;  4P24 A;  2LKF A;  3B07 A;  4IZL A;  2QK7 A;  4TW1 B;  7AHL A;  4H56 A;  4IYC A;  3M4E A;  4P1Y B;  1LKF A;  4P1X B;  4I0N A;  2YGT A;  1T5R A; 
#chains in the Genus database with same CATH topology
 4IYA A;  4U6V A;  4TW1 A;  4Q7G A;  1XEZ A;  4P1Y A;  4P1X A;  3M3R A;  3B07 B;  5K59 A;  1PVL A;  2QK7 B;  3ANZ A;  3O44 A;  5K59 C;  3M4D A;  4YHD A;  3LKF A;  4IDJ A;  3ROH A;  3M2L A;  4J0O A;  4IYT A;  4P24 A;  2LKF A;  3B07 A;  4IZL A;  2QK7 A;  4TW1 B;  7AHL A;  4H56 A;  4IYC A;  3M4E A;  4P1Y B;  1LKF A;  4P1X B;  4I0N A;  2YGT A;  1T5R A; 
#chains in the Genus database with same CATH homology
 4IYA A;  4U6V A;  4TW1 A;  4Q7G A;  4P1Y A;  4P1X A;  3M3R A;  3B07 B;  5K59 A;  2QK7 B;  1PVL A;  3ANZ A;  3O44 A;  5K59 C;  3M4D A;  4YHD A;  4IDJ A;  3LKF A;  3ROH A;  3M2L A;  4J0O A;  4IYT A;  4P24 A;  2LKF A;  3B07 A;  4IZL A;  2QK7 A;  4TW1 B;  7AHL A;  4H56 A;  4IYC A;  3M4E A;  4P1Y B;  1LKF A;  4P1X B;  4I0N A;  2YGT A;  1T5R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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