4J0OA

Structure of the y246a mutant of the panton-valentine leucocidin s component from staphylococcus aureus
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
282
structure length
275
Chain Sequence
NIENIGDGAEVVKRTEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRWPFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGNGSFNYSKTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRDYFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTAGNSYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords LukS-PV
publication title Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
pubmed doi rcsb
source organism Staphylococcus phage pvl
total genus 72
structure length 275
sequence length 282
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-01-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4j0oA00
4IDJA 3O44A 1T5RA 3ANZA 3M4DA 2YGTA 4P1XB 4Q7GA 3B07B 4H56A 4P1XA 4P1YB 3B07A 3M3RA 2QK7B 4P1YA 4J0OA 1PVLA 2QK7A 4IZLA 4U6VA 3LKFA 4IYCA 7AHLA 5K59C 3M4EA 3ROHA 4I0NA 4YHDA 4TW1B 4IYAA 5K59A 2LKFA 4P24A 3M2LA 4TW1A 4IYTA 1LKFA
chains in the Genus database with same CATH superfamily
4IDJA 3O44A 1T5RA 3ANZA 3M4DA 2YGTA 4P1XB 4Q7GA 3B07B 4H56A 4P1XA 4P1YB 3B07A 3M3RA 2QK7B 4P1YA 4J0OA 1PVLA 2QK7A 4IZLA 1XEZA 4U6VA 3LKFA 4IYCA 7AHLA 5K59C 3M4EA 3ROHA 4I0NA 4YHDA 4TW1B 4IYAA 5K59A 2LKFA 4P24A 3M2LA 4TW1A 4IYTA 1LKFA
chains in the Genus database with same CATH topology
4IDJA 3O44A 1T5RA 3ANZA 3M4DA 2YGTA 4P1XB 4Q7GA 3B07B 4H56A 4P1XA 4P1YB 3B07A 3M3RA 2QK7B 4P1YA 4J0OA 1PVLA 2QK7A 4IZLA 4U6VA 3LKFA 4IYCA 7AHLA 5K59C 3M4EA 3ROHA 4I0NA 4YHDA 4TW1B 4IYAA 5K59A 2LKFA 4P24A 3M2LA 4TW1A 4IYTA 1LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IDJ A;  3O44 A;  1T5R A;  3ANZ A;  3M4D A;  2YGT A;  4P1X B;  4Q7G A;  3B07 B;  4H56 A;  4P1X A;  4P1Y B;  3B07 A;  3M3R A;  2QK7 B;  4P1Y A;  4J0O A;  1PVL A;  2QK7 A;  4IZL A;  4U6V A;  3LKF A;  4IYC A;  7AHL A;  5K59 C;  3M4E A;  3ROH A;  4I0N A;  4YHD A;  4TW1 B;  4IYA A;  5K59 A;  2LKF A;  4P24 A;  3M2L A;  4TW1 A;  4IYT A;  1LKF A; 
#chains in the Genus database with same CATH topology
 4IDJ A;  3O44 A;  1T5R A;  3ANZ A;  3M4D A;  2YGT A;  4P1X B;  4Q7G A;  3B07 B;  4H56 A;  4P1X A;  4P1Y B;  3B07 A;  3M3R A;  2QK7 B;  4P1Y A;  4J0O A;  1PVL A;  2QK7 A;  4IZL A;  1XEZ A;  4U6V A;  3LKF A;  4IYC A;  7AHL A;  5K59 C;  3M4E A;  3ROH A;  4I0N A;  4YHD A;  4TW1 B;  4IYA A;  5K59 A;  2LKF A;  4P24 A;  3M2L A;  4TW1 A;  4IYT A;  1LKF A; 
#chains in the Genus database with same CATH homology
 4IDJ A;  3O44 A;  1T5R A;  3ANZ A;  3M4D A;  2YGT A;  4P1X B;  4Q7G A;  3B07 B;  4H56 A;  4P1X A;  4P1Y B;  3B07 A;  3M3R A;  2QK7 B;  4P1Y A;  4J0O A;  1PVL A;  2QK7 A;  4IZL A;  4U6V A;  3LKF A;  4IYC A;  7AHL A;  5K59 C;  3M4E A;  3ROH A;  4I0N A;  4YHD A;  4TW1 B;  4IYA A;  5K59 A;  2LKF A;  4P24 A;  3M2L A;  4TW1 A;  4IYT A;  1LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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