5K59C

Crystal structure of lukgh from staphylococcus aureus in complex with a neutralising antibody
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
282
structure length
276
Chain Sequence
KNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
molecule keywords Uncharacterized leukocidin-like protein 2
publication title Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies.
pubmed doi rcsb
source organism Staphylococcus aureus (strain usa300)
total genus 79
structure length 276
sequence length 282
chains with identical sequence D
ec nomenclature
pdb deposition date 2016-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 5k59C00
1PVLA 4U6VA 4IDJA 1T5RA 7AHLA 3M3RA 3ANZA 3M2LA 4P1YA 4TW1A 4H56A 4IYTA 3B07A 4IYCA 2YGTA 3LKFA 4J0OA 4IZLA 4P1XA 3O44A 2LKFA 1LKFA 4P24A 2QK7B 4I0NA 4IYAA 5K59A 3M4DA 3M4EA 4TW1B 2QK7A 5K59C 3ROHA 3B07B 4P1YB 4YHDA 4Q7GA 4P1XB
chains in the Genus database with same CATH superfamily
1PVLA 4U6VA 4IDJA 1T5RA 7AHLA 3M3RA 3ANZA 3M2LA 4P1YA 4TW1A 4H56A 4IYTA 3B07A 4IYCA 2YGTA 3LKFA 4J0OA 4IZLA 4P1XA 3O44A 2LKFA 1LKFA 4P24A 2QK7B 4I0NA 4IYAA 5K59A 1XEZA 3M4DA 3M4EA 4TW1B 2QK7A 5K59C 3ROHA 3B07B 4P1YB 4YHDA 4Q7GA 4P1XB
chains in the Genus database with same CATH topology
1PVLA 4U6VA 4IDJA 1T5RA 7AHLA 3M3RA 3ANZA 3M2LA 4P1YA 4TW1A 4H56A 4IYTA 3B07A 4IYCA 2YGTA 3LKFA 4J0OA 4IZLA 4P1XA 3O44A 2LKFA 1LKFA 4P24A 2QK7B 4I0NA 4IYAA 5K59A 3M4DA 3M4EA 4TW1B 2QK7A 5K59C 3ROHA 3B07B 4P1YB 4YHDA 4Q7GA 4P1XB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PVL A;  4U6V A;  4IDJ A;  1T5R A;  7AHL A;  3M3R A;  3ANZ A;  3M2L A;  4P1Y A;  4TW1 A;  4H56 A;  4IYT A;  3B07 A;  4IYC A;  2YGT A;  3LKF A;  4J0O A;  4IZL A;  4P1X A;  3O44 A;  2LKF A;  1LKF A;  4P24 A;  2QK7 B;  4I0N A;  4IYA A;  5K59 A;  3M4D A;  3M4E A;  4TW1 B;  2QK7 A;  5K59 C;  3ROH A;  3B07 B;  4P1Y B;  4YHD A;  4Q7G A;  4P1X B; 
#chains in the Genus database with same CATH topology
 1PVL A;  4U6V A;  4IDJ A;  1T5R A;  7AHL A;  3M3R A;  3ANZ A;  3M2L A;  4P1Y A;  4TW1 A;  4H56 A;  4IYT A;  3B07 A;  4IYC A;  2YGT A;  3LKF A;  4J0O A;  4IZL A;  4P1X A;  3O44 A;  2LKF A;  1LKF A;  4P24 A;  2QK7 B;  4I0N A;  4IYA A;  5K59 A;  1XEZ A;  3M4D A;  3M4E A;  4TW1 B;  2QK7 A;  5K59 C;  3ROH A;  3B07 B;  4P1Y B;  4YHD A;  4Q7G A;  4P1X B; 
#chains in the Genus database with same CATH homology
 1PVL A;  4U6V A;  4IDJ A;  1T5R A;  7AHL A;  3M3R A;  3ANZ A;  3M2L A;  4P1Y A;  4TW1 A;  4H56 A;  4IYT A;  3B07 A;  4IYC A;  2YGT A;  3LKF A;  4J0O A;  4IZL A;  4P1X A;  3O44 A;  2LKF A;  1LKF A;  4P24 A;  2QK7 B;  4I0N A;  4IYA A;  5K59 A;  3M4D A;  3M4E A;  4TW1 B;  2QK7 A;  5K59 C;  3ROH A;  3B07 B;  4P1Y B;  4YHD A;  4Q7G A;  4P1X B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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