3M4DA

Crystal structure of the m113n mutant of alpha-hemolysin
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
293
structure length
293
Chain Sequence
ADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYNSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Alpha-hemolysin
publication title Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 61
structure length 293
sequence length 293
chains with identical sequence B, C, D, E, F, G
ec nomenclature
pdb deposition date 2010-03-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 3m4dA00
4J0OA 5K59C 4P24A 4Q7GA 3ANZA 3M4EA 3LKFA 4IYTA 5K59A 4P1XA 2LKFA 3M4DA 2YGTA 4I0NA 1PVLA 4P1YB 3M2LA 2QK7B 4P1YA 7AHLA 4IYAA 3ROHA 4IYCA 2QK7A 1T5RA 3B07B 4IDJA 3O44A 3M3RA 4TW1B 3B07A 4IZLA 4H56A 1LKFA 4YHDA 4P1XB 4U6VA 4TW1A
chains in the Genus database with same CATH superfamily
4J0OA 5K59C 4P24A 4Q7GA 3ANZA 3M4EA 3LKFA 4IYTA 5K59A 4P1XA 2LKFA 3M4DA 2YGTA 4I0NA 1PVLA 4P1YB 3M2LA 1XEZA 2QK7B 4P1YA 7AHLA 4IYAA 3ROHA 4IYCA 2QK7A 1T5RA 3B07B 4IDJA 3O44A 3M3RA 4TW1B 3B07A 4IZLA 4H56A 1LKFA 4YHDA 4P1XB 4U6VA 4TW1A
chains in the Genus database with same CATH topology
4J0OA 5K59C 4P24A 4Q7GA 3ANZA 3M4EA 3LKFA 4IYTA 5K59A 4P1XA 2LKFA 3M4DA 2YGTA 4I0NA 1PVLA 4P1YB 3M2LA 2QK7B 4P1YA 7AHLA 4IYAA 3ROHA 4IYCA 2QK7A 1T5RA 3B07B 4IDJA 3O44A 3M3RA 4TW1B 3B07A 4IZLA 4H56A 1LKFA 4YHDA 4P1XB 4U6VA 4TW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J0O A;  5K59 C;  4P24 A;  4Q7G A;  3ANZ A;  3M4E A;  3LKF A;  4IYT A;  5K59 A;  4P1X A;  2LKF A;  3M4D A;  2YGT A;  4I0N A;  1PVL A;  4P1Y B;  3M2L A;  2QK7 B;  4P1Y A;  7AHL A;  4IYA A;  3ROH A;  4IYC A;  2QK7 A;  1T5R A;  3B07 B;  4IDJ A;  3O44 A;  3M3R A;  4TW1 B;  3B07 A;  4IZL A;  4H56 A;  1LKF A;  4YHD A;  4P1X B;  4U6V A;  4TW1 A; 
#chains in the Genus database with same CATH topology
 4J0O A;  5K59 C;  4P24 A;  4Q7G A;  3ANZ A;  3M4E A;  3LKF A;  4IYT A;  5K59 A;  4P1X A;  2LKF A;  3M4D A;  2YGT A;  4I0N A;  1PVL A;  4P1Y B;  3M2L A;  1XEZ A;  2QK7 B;  4P1Y A;  7AHL A;  4IYA A;  3ROH A;  4IYC A;  2QK7 A;  1T5R A;  3B07 B;  4IDJ A;  3O44 A;  3M3R A;  4TW1 B;  3B07 A;  4IZL A;  4H56 A;  1LKF A;  4YHD A;  4P1X B;  4U6V A;  4TW1 A; 
#chains in the Genus database with same CATH homology
 4J0O A;  5K59 C;  4P24 A;  4Q7G A;  3ANZ A;  3M4E A;  3LKF A;  4IYT A;  5K59 A;  4P1X A;  2LKF A;  3M4D A;  2YGT A;  4I0N A;  1PVL A;  4P1Y B;  3M2L A;  2QK7 B;  4P1Y A;  7AHL A;  4IYA A;  3ROH A;  4IYC A;  2QK7 A;  1T5R A;  3B07 B;  4IDJ A;  3O44 A;  3M3R A;  4TW1 B;  3B07 A;  4IZL A;  4H56 A;  1LKF A;  4YHD A;  4P1X B;  4U6V A;  4TW1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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