1AER | Genus

Total Genus 46

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	46
sequence length	211
structure length	205
Chain Sequence	AFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRAAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQPGKPPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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Time for openFile(/file/5cfab4bf8d8b5dc9a8ec236b/pdb.gz): 1316 ms

reading 205 atoms

ModelSet: haveSymmetry:false haveUnitcells:false haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

205 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically

Time for creating model: 21 ms

Adding embedded #jmolscript: select ({0:204});backbone only;select *;

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Adp-ribosylation
source organism	Pseudomonas aeruginosa
publication title	Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation pubmed doi rcsb
molecule keywords	EXOTOXIN A
total genus	46
structure length	205
sequence length	211
chains with identical sequence	B
ec nomenclature	ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date	1995-12-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF09009	Exotox-A_cataly	Exotoxin A catalytic

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.175.10	Alpha Beta	Alpha-Beta Complex	Diphtheria Toxin; domain 1	Diphtheria Toxin, domain 1	1aerA00

5I82A 3KI1A 1IKPA 1DDTA 1ZM3B 1XDTT 3B78B 3KI4A 4OW6A 1IKQA 3KI7A 2Q6MA 3ESSA 1ZM9B 3KI5A 4AE0A 1MDTA 3B8HB 1DMAA 3KI6A 1TOXA 1ZM4B 3KI2A 1SGKA 4AE1A 1XK9A 3KI0A 3KI3A 3Q9OA 2Q5TA 1F0LA 1AERA 3NY6A 2ZITB 1DTPA 3B82B 1ZM2B
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5I82 A;  3KI1 A;  1IKP A;  1DDT A;  1ZM3 B;  1XDT T;  3B78 B;  3KI4 A;  4OW6 A;  1IKQ A;  3KI7 A;  2Q6M A;  3ESS A;  1ZM9 B;  3KI5 A;  4AE0 A;  1MDT A;  3B8H B;  1DMA A;  3KI6 A;  1TOX A;  1ZM4 B;  3KI2 A;  1SGK A;  4AE1 A;  1XK9 A;  3KI0 A;  3KI3 A;  3Q9O A;  2Q5T A;  1F0L A;  1AER A;  3NY6 A;  2ZIT B;  1DTP A;  3B82 B;  1ZM2 B; 
#chains in the Genus database with same CATH topology
 5I82 A;  3KI1 A;  1IKP A;  1DDT A;  1ZM3 B;  1XDT T;  3B78 B;  3KI4 A;  4OW6 A;  1IKQ A;  3KI7 A;  2Q6M A;  3ESS A;  1ZM9 B;  3KI5 A;  4AE0 A;  1MDT A;  3B8H B;  1DMA A;  3KI6 A;  1TOX A;  1ZM4 B;  3KI2 A;  1SGK A;  4AE1 A;  1XK9 A;  3KI0 A;  3KI3 A;  3Q9O A;  2Q5T A;  1F0L A;  1AER A;  3NY6 A;  2ZIT B;  1DTP A;  3B82 B;  1ZM2 B; 
#chains in the Genus database with same CATH homology
 5I82 A;  3KI1 A;  1IKP A;  1DDT A;  1ZM3 B;  1XDT T;  3B78 B;  3KI4 A;  4OW6 A;  1IKQ A;  3KI7 A;  2Q6M A;  3ESS A;  1ZM9 B;  3KI5 A;  4AE0 A;  1MDT A;  3B8H B;  1DMA A;  3KI6 A;  1TOX A;  1ZM4 B;  3KI2 A;  1SGK A;  4AE1 A;  1XK9 A;  3KI0 A;  3KI3 A;  3Q9O A;  2Q5T A;  1F0L A;  1AER A;  3NY6 A;  2ZIT B;  1DTP A;  3B82 B;  1ZM2 B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AERA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations