1AER | Genus

Total Genus 46

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	46
sequence length	211
structure length	205
Chain Sequence	AFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQSIVFGGVRAAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGALLRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEEGGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALPDYASQPGKPPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 205 atoms

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205 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Adp-ribosylation
source organism	Pseudomonas aeruginosa
publication title	Crystal structure of the catalytic domain of Pseudomonas exotoxin A complexed with a nicotinamide adenine dinucleotide analog: implications for the activation process and for ADP ribosylation pubmed doi rcsb
molecule keywords	EXOTOXIN A
total genus	46
structure length	205
sequence length	211
chains with identical sequence	B
ec nomenclature	ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date	1995-12-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF09009	Exotox-A_cataly	Exotoxin A catalytic

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.90.175.10	Alpha Beta	Alpha-Beta Complex	Diphtheria Toxin; domain 1	Diphtheria Toxin, domain 1	1aerA00

2Q6MA 1ZM3B 4AE0A 3B78B 1IKQA 1TOXA 1F0LA 3KI0A 3KI3A 3KI1A 1XK9A 1XDTT 3NY6A 1MDTA 3KI5A 1ZM2B 3B82B 1SGKA 3KI4A 1AERA 1DDTA 3ESSA 2ZITB 4OW6A 1DMAA 1ZM4B 1ZM9B 1IKPA 5I82A 3KI2A 2Q5TA 3KI7A 1DTPA 4AE1A 3KI6A 3B8HB 3Q9OA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 2Q6M A;  1ZM3 B;  4AE0 A;  3B78 B;  1IKQ A;  1TOX A;  1F0L A;  3KI0 A;  3KI3 A;  3KI1 A;  1XK9 A;  1XDT T;  3NY6 A;  1MDT A;  3KI5 A;  1ZM2 B;  3B82 B;  1SGK A;  3KI4 A;  1AER A;  1DDT A;  3ESS A;  2ZIT B;  4OW6 A;  1DMA A;  1ZM4 B;  1ZM9 B;  1IKP A;  5I82 A;  3KI2 A;  2Q5T A;  3KI7 A;  1DTP A;  4AE1 A;  3KI6 A;  3B8H B;  3Q9O A; 
#chains in the Genus database with same CATH topology
 2Q6M A;  1ZM3 B;  4AE0 A;  3B78 B;  1IKQ A;  1TOX A;  1F0L A;  3KI0 A;  3KI3 A;  3KI1 A;  1XK9 A;  1XDT T;  3NY6 A;  1MDT A;  3KI5 A;  1ZM2 B;  3B82 B;  1SGK A;  3KI4 A;  1AER A;  1DDT A;  3ESS A;  2ZIT B;  4OW6 A;  1DMA A;  1ZM4 B;  1ZM9 B;  1IKP A;  5I82 A;  3KI2 A;  2Q5T A;  3KI7 A;  1DTP A;  4AE1 A;  3KI6 A;  3B8H B;  3Q9O A; 
#chains in the Genus database with same CATH homology
 2Q6M A;  1ZM3 B;  4AE0 A;  3B78 B;  1IKQ A;  1TOX A;  1F0L A;  3KI0 A;  3KI3 A;  3KI1 A;  1XK9 A;  1XDT T;  3NY6 A;  1MDT A;  3KI5 A;  1ZM2 B;  3B82 B;  1SGK A;  3KI4 A;  1AER A;  1DDT A;  3ESS A;  2ZIT B;  4OW6 A;  1DMA A;  1ZM4 B;  1ZM9 B;  1IKP A;  5I82 A;  3KI2 A;  2Q5T A;  3KI7 A;  1DTP A;  4AE1 A;  3KI6 A;  3B8H B;  3Q9O A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AERA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations