1DTPA

The structure of the isolated catalytic domain of diphtheria toxin
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
190
structure length
190
Chain Sequence
GADDVVDSSKSFVMENFSSYHGTKPGYVDSIQKGIQKPKSGTQGNYDDDWKGFYSTDNKYDAAGYSVDNENPLSGKAGGVVKVTYPGLTKVLALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLPFAEGSSSVEYINNWEQAKALSVELEINFETRGKRGQDAMYEYMAQACAGNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
source organism Corynephage beta
publication title Structure of the isolated catalytic domain of diphtheria toxin.
pubmed doi rcsb
molecule keywords DIPHTHERIA TOXIN
total genus 50
structure length 190
sequence length 190
ec nomenclature ec 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
pdb deposition date 1994-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02763 Diphtheria_C Diphtheria toxin, C domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.175.10 Alpha Beta Alpha-Beta Complex Diphtheria Toxin; domain 1 Diphtheria Toxin, domain 1 1dtpA00
5I82A 1ZM4B 2ZITB 1IKQA 1DTPA 3KI1A 1F0LA 4AE0A 3NY6A 3KI2A 1SGKA 1IKPA 1TOXA 3KI7A 3ESSA 3B78B 3KI3A 1ZM2B 3Q9OA 3KI6A 2Q5TA 4AE1A 1AERA 2Q6MA 1XK9A 1ZM9B 1DDTA 3KI5A 1ZM3B 3KI0A 1DMAA 1MDTA 3B82B 3KI4A 3B8HB 1XDTT 4OW6A
chains in the Genus database with same CATH superfamily
5I82A 1ZM4B 2ZITB 1IKQA 1DTPA 3KI1A 1F0LA 4AE0A 3NY6A 3KI2A 1SGKA 1IKPA 1TOXA 3KI7A 3ESSA 3B78B 3KI3A 1ZM2B 3Q9OA 3KI6A 2Q5TA 4AE1A 1AERA 2Q6MA 1XK9A 1ZM9B 1DDTA 3KI5A 1ZM3B 3KI0A 1DMAA 1MDTA 3B82B 3KI4A 3B8HB 1XDTT 4OW6A
chains in the Genus database with same CATH topology
5I82A 1ZM4B 2ZITB 1IKQA 1DTPA 3KI1A 1F0LA 4AE0A 3NY6A 3KI2A 1SGKA 1IKPA 1TOXA 3KI7A 3ESSA 3B78B 3KI3A 1ZM2B 3Q9OA 3KI6A 2Q5TA 4AE1A 1AERA 2Q6MA 1XK9A 1ZM9B 1DDTA 3KI5A 1ZM3B 3KI0A 1DMAA 1MDTA 3B82B 3KI4A 3B8HB 1XDTT 4OW6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5I82 A;  1ZM4 B;  2ZIT B;  1IKQ A;  1DTP A;  3KI1 A;  1F0L A;  4AE0 A;  3NY6 A;  3KI2 A;  1SGK A;  1IKP A;  1TOX A;  3KI7 A;  3ESS A;  3B78 B;  3KI3 A;  1ZM2 B;  3Q9O A;  3KI6 A;  2Q5T A;  4AE1 A;  1AER A;  2Q6M A;  1XK9 A;  1ZM9 B;  1DDT A;  3KI5 A;  1ZM3 B;  3KI0 A;  1DMA A;  1MDT A;  3B82 B;  3KI4 A;  3B8H B;  1XDT T;  4OW6 A; 
#chains in the Genus database with same CATH topology
 5I82 A;  1ZM4 B;  2ZIT B;  1IKQ A;  1DTP A;  3KI1 A;  1F0L A;  4AE0 A;  3NY6 A;  3KI2 A;  1SGK A;  1IKP A;  1TOX A;  3KI7 A;  3ESS A;  3B78 B;  3KI3 A;  1ZM2 B;  3Q9O A;  3KI6 A;  2Q5T A;  4AE1 A;  1AER A;  2Q6M A;  1XK9 A;  1ZM9 B;  1DDT A;  3KI5 A;  1ZM3 B;  3KI0 A;  1DMA A;  1MDT A;  3B82 B;  3KI4 A;  3B8H B;  1XDT T;  4OW6 A; 
#chains in the Genus database with same CATH homology
 5I82 A;  1ZM4 B;  2ZIT B;  1IKQ A;  1DTP A;  3KI1 A;  1F0L A;  4AE0 A;  3NY6 A;  3KI2 A;  1SGK A;  1IKP A;  1TOX A;  3KI7 A;  3ESS A;  3B78 B;  3KI3 A;  1ZM2 B;  3Q9O A;  3KI6 A;  2Q5T A;  4AE1 A;  1AER A;  2Q6M A;  1XK9 A;  1ZM9 B;  1DDT A;  3KI5 A;  1ZM3 B;  3KI0 A;  1DMA A;  1MDT A;  3B82 B;  3KI4 A;  3B8H B;  1XDT T;  4OW6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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