1EYSL

Crystal structure of photosynthetic reaction center from a thermophilic bacterium, thermochromatium tepidum
Total Genus 99
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
99
sequence length
280
structure length
280
Chain Sequence
AMLSFEKKYRVRGGTLIGGDLFDFWVGPFYVGFFGVVGFCFTLLGVLLIVWGATIGPTGPTSDLQTYNLWRISIAPPDLSYGLRMAPLTEGGLWQIITICAAGAFISWALREVEICRKLGIGFHVPFAFSFAIGAYLVLVFVRPLLMGAWGHGFPYGILSHLDWVSNVGYQFLHFHYNPAHMLAISFFFTNCLALSMHGSLILSVTNPQRGEPVKTSEHENTFFRDIVGYSIGALAIHRLGLFLALSAAFWSAVCILISGPFWTRGWPEWWNWWLELPLW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of photosynthetic reaction center and high-potential iron-sulfur protein from Thermochromatium tepidum: thermostability and electron transfer.
pubmed doi rcsb
molecule keywords PHOTOSYNTHETIC REACTION CENTER
molecule tags Electron transport
total genus 99
structure length 280
sequence length 280
ec nomenclature
pdb deposition date 2000-05-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.85.10 Mainly Alpha Up-down Bundle Photosynthetic Reaction Center, subunit M; domain 1 Photosystem II protein D1-like 1eysL01
1.20.85.10 Mainly Alpha Up-down Bundle Photosynthetic Reaction Center, subunit M; domain 1 Photosystem II protein D1-like 1eysL02
2BOZL 2GMRM 4HBJM 1YF6L 2UX5L 3WMMM 3DUQM 1L9BL 1UMXM 2WX5L 1OGVM 3ZUWL 3T6DM 2UWWL 4TQQL 4HBHL 1E14L 2HITM 5PRCM 1F6NM 2HJ6L 1DXRM 2JIYL 1L9JL 1RG5M 1EYSL 1QOVL 1JGXM 1JH0M 3DU3M 2UXJL 2BNSB 4CASB 1JGZL 1DS8L 1DV3L 1KBYM 4HBHM 4N7KL 7PRCM 4IN5L 1JGYL 1PCRM 2BNPA 1AIJL 1RQKL 2J8DL 1FNQM 2PRCM 2RCRM 1K6LL 4H9LM 2J8CM 2HG9M 1EYSM 1PSSM 2UXKL 2UWTM 1RGNM 1JGWL 3PRCL 1RVJL 2I5NL 3D38L 2JBLL 1R2CM 2HH1M 3V3ZM 2UWUL 3DSYL 1DS8M 5LSEM 2UWVL 1PSTL 1RZZL 2HHKM 2WJNL 2X5UM 1AIGL 2UXLL 2HG3L 1E6DL 1M3XL 2I5NM 1DV6M 2WJMM 5LRIL 1FNPM 2BOZM 3DTSL 1YF6M 2UX5M 3G7FL 3I4DL 2X5VL 3DTRL 1L9BM 2WX5M 1S00L 4RCRL 6PRCL 3ZUWM 2UWWM 3V3YL 2BNSA 4TQQM 4LWYL 1YSTL 1RZHL 1RY5L 1E14M 1MPSL 2UWSL 3DTAL 1VRNL 2HJ6M 3I4DM 2JIYM 1L9JM 1QOVM 2UX4L 3DU2L 2UXJM 4IN6L 3T6EL 4N7LL 1JGZM 1DV3M 4N7KM 4CASC 4IN5M 1JGYM 1K6NL 2J8DM 1AIJM 1RQKM 1K6LM 2GNUL 2UXKM 1JGWM 4IN7L 3PRCM 1RVJM 2JJ0L 4N7LM 3D38M 2JBLM 2UX3L 2UXML 2GMRL 2UWUM 3DSYM 4HBJL 3WMML 2UWVM 3DUQL 1PSTM 1RZZM 2WJNM 1OGVL 3T6DL 1AIGM 2UXLM 2HG3M 1E6DM 1M3XM 5LRIM 2HITL 3DTSM 1F6NL 3ZUML 1DXRL 3G7FM 2X5VM 3DTRM 1RG5L 1JH0L 1JGXL 1S00M 3DU3L 1PRCL 4H99L 4RCRM 6PRCM 3V3YM 4LWYM 1KBYL 1RZHM 1YSTM 1RY5M 1MPSM 7PRCL 2UWSM 1PCRL 2RCRL 1VRNM 3DTAM 5PRCL 4H9LL 1FNQL 2PRCL 3ZUMM 2J8CL 2HG9L 1PSSL 2UWTL 2UX4M 1RGNL 3DU2M 4H99M 4IN6M 1PRCM 3T6EM 1R2CL 2HH1L 3V3ZL 2BNPB 5LSEL 1UMXL 1K6NM 2HHKL 2GNUM 2X5UL 4IN7M 2JJ0M 2UX3M 1DV6L 2WJML 2UXMM 1FNPL
chains in the Genus database with same CATH superfamily
2BOZL 2GMRM 4HBJM 1YF6L 2UX5L 3WMMM 3DUQM 1L9BL 1UMXM 2WX5L 1OGVM 3ZUWL 3T6DM 3VKWA 2UWWL 4TQQL 4HBHL 1E14L 2HITM 5PRCM 1F6NM 2HJ6L 1DXRM 2JIYL 1L9JL 1RG5M 1EYSL 1QOVL 1JGXM 1JH0M 3DU3M 2UXJL 2BNSB 4CASB 1JGZL 1DS8L 1DV3L 1KBYM 4HBHM 4N7KL 7PRCM 4IN5L 1JGYL 1PCRM 2BNPA 1AIJL 1RQKL 2J8DL 1FNQM 2PRCM 2RCRM 1K6LL 4H9LM 2J8CM 2HG9M 1EYSM 1PSSM 2UXKL 2UWTM 1RGNM 1JGWL 3PRCL 1RVJL 2I5NL 3D38L 2JBLL 1R2CM 2HH1M 3V3ZM 2UWUL 3DSYL 1DS8M 5LSEM 2UWVL 1PSTL 1RZZL 2HHKM 2WJNL 2X5UM 1AIGL 2UXLL 2HG3L 1E6DL 1M3XL 2I5NM 1DV6M 2WJMM 5LRIL 1FNPM 2BOZM 3DTSL 1YF6M 2UX5M 3G7FL 3I4DL 2X5VL 3DTRL 1L9BM 2WX5M 1S00L 4RCRL 6PRCL 3ZUWM 2UWWM 3V3YL 2BNSA 4TQQM 4LWYL 3WRYC 1YSTL 1RZHL 1RY5L 1E14M 1MPSL 2UWSL 3DTAL 1VRNL 2HJ6M 3I4DM 2JIYM 1L9JM 1QOVM 2UX4L 3DU2L 2UXJM 4IN6L 3T6EL 4N7LL 1JGZM 1DV3M 4N7KM 4CASC 4IN5M 1JGYM 1K6NL 2J8DM 1AIJM 1RQKM 1K6LM 2GNUL 2UXKM 1JGWM 4IN7L 3PRCM 1RVJM 2JJ0L 4N7LM 3D38M 2JBLM 2UX3L 2UXML 2GMRL 2UWUM 3DSYM 4HBJL 3WMML 2UWVM 3DUQL 1PSTM 1RZZM 2WJNM 1OGVL 3T6DL 1AIGM 2UXLM 2HG3M 1E6DM 1M3XM 5LRIM 2HITL 3DTSM 1F6NL 3ZUML 1DXRL 3G7FM 2X5VM 3DTRM 1RG5L 1JH0L 1JGXL 1S00M 3DU3L 1PRCL 4H99L 4RCRM 6PRCM 3V3YM 4LWYM 1KBYL 1RZHM 1YSTM 1RY5M 1MPSM 7PRCL 2UWSM 1PCRL 2RCRL 1VRNM 3DTAM 5PRCL 4H9LL 1FNQL 2PRCL 3ZUMM 2J8CL 2HG9L 1PSSL 2UWTL 2UX4M 3WRXC 1RGNL 3DU2M 4H99M 4IN6M 1PRCM 3T6EM 1R2CL 2HH1L 3V3ZL 2BNPB 5LSEL 1UMXL 1K6NM 2HHKL 2GNUM 2X5UL 4IN7M 2JJ0M 2UX3M 1DV6L 2WJML 2UXMM 1FNPL
chains in the Genus database with same CATH topology
2BOZL 2GMRM 4HBJM 1YF6L 2UX5L 3WMMM 3DUQM 1L9BL 1UMXM 2WX5L 1OGVM 3ZUWL 3T6DM 2UWWL 4TQQL 4HBHL 1E14L 2HITM 5PRCM 1F6NM 2HJ6L 1DXRM 2JIYL 1L9JL 1RG5M 1EYSL 1QOVL 1JGXM 1JH0M 3DU3M 2UXJL 2BNSB 4CASB 1JGZL 1DS8L 1DV3L 1KBYM 4HBHM 4N7KL 7PRCM 4IN5L 1JGYL 1PCRM 2BNPA 1AIJL 1RQKL 2J8DL 1FNQM 2PRCM 2RCRM 1K6LL 4H9LM 2J8CM 2HG9M 1EYSM 1PSSM 2UXKL 2UWTM 1RGNM 1JGWL 3PRCL 1RVJL 2I5NL 3D38L 2JBLL 1R2CM 2HH1M 3V3ZM 2UWUL 3DSYL 1DS8M 5LSEM 2UWVL 1PSTL 1RZZL 2HHKM 2WJNL 2X5UM 1AIGL 2UXLL 2HG3L 1E6DL 1M3XL 2I5NM 1DV6M 2WJMM 5LRIL 1FNPM 2BOZM 3DTSL 1YF6M 2UX5M 3G7FL 3I4DL 2X5VL 3DTRL 1L9BM 2WX5M 1S00L 4RCRL 6PRCL 3ZUWM 2UWWM 3V3YL 2BNSA 4TQQM 4LWYL 1YSTL 1RZHL 1RY5L 1E14M 1MPSL 2UWSL 3DTAL 1VRNL 2HJ6M 3I4DM 2JIYM 1L9JM 1QOVM 2UX4L 3DU2L 2UXJM 4IN6L 3T6EL 4N7LL 1JGZM 1DV3M 4N7KM 4CASC 4IN5M 1JGYM 1K6NL 2J8DM 1AIJM 1RQKM 1K6LM 2GNUL 2UXKM 1JGWM 4IN7L 3PRCM 1RVJM 2JJ0L 4N7LM 3D38M 2JBLM 2UX3L 2UXML 2GMRL 2UWUM 3DSYM 4HBJL 3WMML 2UWVM 3DUQL 1PSTM 1RZZM 2WJNM 1OGVL 3T6DL 1AIGM 2UXLM 2HG3M 1E6DM 1M3XM 5LRIM 2HITL 3DTSM 1F6NL 3ZUML 1DXRL 3G7FM 2X5VM 3DTRM 1RG5L 1JH0L 1JGXL 1S00M 3DU3L 1PRCL 4H99L 4RCRM 6PRCM 3V3YM 4LWYM 1KBYL 1RZHM 1YSTM 1RY5M 1MPSM 7PRCL 2UWSM 1PCRL 2RCRL 1VRNM 3DTAM 5PRCL 4H9LL 1FNQL 2PRCL 3ZUMM 2J8CL 2HG9L 1PSSL 2UWTL 2UX4M 1RGNL 3DU2M 4H99M 4IN6M 1PRCM 3T6EM 1R2CL 2HH1L 3V3ZL 2BNPB 5LSEL 1UMXL 1K6NM 2HHKL 2GNUM 2X5UL 4IN7M 2JJ0M 2UX3M 1DV6L 2WJML 2UXMM 1FNPL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BOZ L;  2GMR M;  4HBJ M;  1YF6 L;  2UX5 L;  3WMM M;  3DUQ M;  1L9B L;  1UMX M;  2WX5 L;  1OGV M;  3ZUW L;  3T6D M;  2UWW L;  4TQQ L;  4HBH L;  1E14 L;  2HIT M;  5PRC M;  1F6N M;  2HJ6 L;  1DXR M;  2JIY L;  1L9J L;  1RG5 M;  1EYS L;  1QOV L;  1JGX M;  1JH0 M;  3DU3 M;  2UXJ L;  2BNS B;  4CAS B;  1JGZ L;  1DS8 L;  1DV3 L;  1KBY M;  4HBH M;  4N7K L;  7PRC M;  4IN5 L;  1JGY L;  1PCR M;  2BNP A;  1AIJ L;  1RQK L;  2J8D L;  1FNQ M;  2PRC M;  2RCR M;  1K6L L;  4H9L M;  2J8C M;  2HG9 M;  1EYS M;  1PSS M;  2UXK L;  2UWT M;  1RGN M;  1JGW L;  3PRC L;  1RVJ L;  2I5N L;  3D38 L;  2JBL L;  1R2C M;  2HH1 M;  3V3Z M;  2UWU L;  3DSY L;  1DS8 M;  5LSE M;  2UWV L;  1PST L;  1RZZ L;  2HHK M;  2WJN L;  2X5U M;  1AIG L;  2UXL L;  2HG3 L;  1E6D L;  1M3X L;  2I5N M;  1DV6 M;  2WJM M;  5LRI L;  1FNP M;  2BOZ M;  3DTS L;  1YF6 M;  2UX5 M;  3G7F L;  3I4D L;  2X5V L;  3DTR L;  1L9B M;  2WX5 M;  1S00 L;  4RCR L;  6PRC L;  3ZUW M;  2UWW M;  3V3Y L;  2BNS A;  4TQQ M;  4LWY L;  1YST L;  1RZH L;  1RY5 L;  1E14 M;  1MPS L;  2UWS L;  3DTA L;  1VRN L;  2HJ6 M;  3I4D M;  2JIY M;  1L9J M;  1QOV M;  2UX4 L;  3DU2 L;  2UXJ M;  4IN6 L;  3T6E L;  4N7L L;  1JGZ M;  1DV3 M;  4N7K M;  4CAS C;  4IN5 M;  1JGY M;  1K6N L;  2J8D M;  1AIJ M;  1RQK M;  1K6L M;  2GNU L;  2UXK M;  1JGW M;  4IN7 L;  3PRC M;  1RVJ M;  2JJ0 L;  4N7L M;  3D38 M;  2JBL M;  2UX3 L;  2UXM L;  2GMR L;  2UWU M;  3DSY M;  4HBJ L;  3WMM L;  2UWV M;  3DUQ L;  1PST M;  1RZZ M;  2WJN M;  1OGV L;  3T6D L;  1AIG M;  2UXL M;  2HG3 M;  1E6D M;  1M3X M;  5LRI M;  2HIT L;  3DTS M;  1F6N L;  3ZUM L;  1DXR L;  3G7F M;  2X5V M;  3DTR M;  1RG5 L;  1JH0 L;  1JGX L;  1S00 M;  3DU3 L;  1PRC L;  4H99 L;  4RCR M;  6PRC M;  3V3Y M;  4LWY M;  1KBY L;  1RZH M;  1YST M;  1RY5 M;  1MPS M;  7PRC L;  2UWS M;  1PCR L;  2RCR L;  1VRN M;  3DTA M;  5PRC L;  4H9L L;  1FNQ L;  2PRC L;  3ZUM M;  2J8C L;  2HG9 L;  1PSS L;  2UWT L;  2UX4 M;  1RGN L;  3DU2 M;  4H99 M;  4IN6 M;  1PRC M;  3T6E M;  1R2C L;  2HH1 L;  3V3Z L;  2BNP B;  5LSE L;  1UMX L;  1K6N M;  2HHK L;  2GNU M;  2X5U L;  4IN7 M;  2JJ0 M;  2UX3 M;  1DV6 L;  2WJM L;  2UXM M;  1FNP L; 
#chains in the Genus database with same CATH topology
 2BOZ L;  2GMR M;  4HBJ M;  1YF6 L;  2UX5 L;  3WMM M;  3DUQ M;  1L9B L;  1UMX M;  2WX5 L;  1OGV M;  3ZUW L;  3T6D M;  3VKW A;  2UWW L;  4TQQ L;  4HBH L;  1E14 L;  2HIT M;  5PRC M;  1F6N M;  2HJ6 L;  1DXR M;  2JIY L;  1L9J L;  1RG5 M;  1EYS L;  1QOV L;  1JGX M;  1JH0 M;  3DU3 M;  2UXJ L;  2BNS B;  4CAS B;  1JGZ L;  1DS8 L;  1DV3 L;  1KBY M;  4HBH M;  4N7K L;  7PRC M;  4IN5 L;  1JGY L;  1PCR M;  2BNP A;  1AIJ L;  1RQK L;  2J8D L;  1FNQ M;  2PRC M;  2RCR M;  1K6L L;  4H9L M;  2J8C M;  2HG9 M;  1EYS M;  1PSS M;  2UXK L;  2UWT M;  1RGN M;  1JGW L;  3PRC L;  1RVJ L;  2I5N L;  3D38 L;  2JBL L;  1R2C M;  2HH1 M;  3V3Z M;  2UWU L;  3DSY L;  1DS8 M;  5LSE M;  2UWV L;  1PST L;  1RZZ L;  2HHK M;  2WJN L;  2X5U M;  1AIG L;  2UXL L;  2HG3 L;  1E6D L;  1M3X L;  2I5N M;  1DV6 M;  2WJM M;  5LRI L;  1FNP M;  2BOZ M;  3DTS L;  1YF6 M;  2UX5 M;  3G7F L;  3I4D L;  2X5V L;  3DTR L;  1L9B M;  2WX5 M;  1S00 L;  4RCR L;  6PRC L;  3ZUW M;  2UWW M;  3V3Y L;  2BNS A;  4TQQ M;  4LWY L;  3WRY C;  1YST L;  1RZH L;  1RY5 L;  1E14 M;  1MPS L;  2UWS L;  3DTA L;  1VRN L;  2HJ6 M;  3I4D M;  2JIY M;  1L9J M;  1QOV M;  2UX4 L;  3DU2 L;  2UXJ M;  4IN6 L;  3T6E L;  4N7L L;  1JGZ M;  1DV3 M;  4N7K M;  4CAS C;  4IN5 M;  1JGY M;  1K6N L;  2J8D M;  1AIJ M;  1RQK M;  1K6L M;  2GNU L;  2UXK M;  1JGW M;  4IN7 L;  3PRC M;  1RVJ M;  2JJ0 L;  4N7L M;  3D38 M;  2JBL M;  2UX3 L;  2UXM L;  2GMR L;  2UWU M;  3DSY M;  4HBJ L;  3WMM L;  2UWV M;  3DUQ L;  1PST M;  1RZZ M;  2WJN M;  1OGV L;  3T6D L;  1AIG M;  2UXL M;  2HG3 M;  1E6D M;  1M3X M;  5LRI M;  2HIT L;  3DTS M;  1F6N L;  3ZUM L;  1DXR L;  3G7F M;  2X5V M;  3DTR M;  1RG5 L;  1JH0 L;  1JGX L;  1S00 M;  3DU3 L;  1PRC L;  4H99 L;  4RCR M;  6PRC M;  3V3Y M;  4LWY M;  1KBY L;  1RZH M;  1YST M;  1RY5 M;  1MPS M;  7PRC L;  2UWS M;  1PCR L;  2RCR L;  1VRN M;  3DTA M;  5PRC L;  4H9L L;  1FNQ L;  2PRC L;  3ZUM M;  2J8C L;  2HG9 L;  1PSS L;  2UWT L;  2UX4 M;  3WRX C;  1RGN L;  3DU2 M;  4H99 M;  4IN6 M;  1PRC M;  3T6E M;  1R2C L;  2HH1 L;  3V3Z L;  2BNP B;  5LSE L;  1UMX L;  1K6N M;  2HHK L;  2GNU M;  2X5U L;  4IN7 M;  2JJ0 M;  2UX3 M;  1DV6 L;  2WJM L;  2UXM M;  1FNP L; 
#chains in the Genus database with same CATH homology
 2BOZ L;  2GMR M;  4HBJ M;  1YF6 L;  2UX5 L;  3WMM M;  3DUQ M;  1L9B L;  1UMX M;  2WX5 L;  1OGV M;  3ZUW L;  3T6D M;  2UWW L;  4TQQ L;  4HBH L;  1E14 L;  2HIT M;  5PRC M;  1F6N M;  2HJ6 L;  1DXR M;  2JIY L;  1L9J L;  1RG5 M;  1EYS L;  1QOV L;  1JGX M;  1JH0 M;  3DU3 M;  2UXJ L;  2BNS B;  4CAS B;  1JGZ L;  1DS8 L;  1DV3 L;  1KBY M;  4HBH M;  4N7K L;  7PRC M;  4IN5 L;  1JGY L;  1PCR M;  2BNP A;  1AIJ L;  1RQK L;  2J8D L;  1FNQ M;  2PRC M;  2RCR M;  1K6L L;  4H9L M;  2J8C M;  2HG9 M;  1EYS M;  1PSS M;  2UXK L;  2UWT M;  1RGN M;  1JGW L;  3PRC L;  1RVJ L;  2I5N L;  3D38 L;  2JBL L;  1R2C M;  2HH1 M;  3V3Z M;  2UWU L;  3DSY L;  1DS8 M;  5LSE M;  2UWV L;  1PST L;  1RZZ L;  2HHK M;  2WJN L;  2X5U M;  1AIG L;  2UXL L;  2HG3 L;  1E6D L;  1M3X L;  2I5N M;  1DV6 M;  2WJM M;  5LRI L;  1FNP M;  2BOZ M;  3DTS L;  1YF6 M;  2UX5 M;  3G7F L;  3I4D L;  2X5V L;  3DTR L;  1L9B M;  2WX5 M;  1S00 L;  4RCR L;  6PRC L;  3ZUW M;  2UWW M;  3V3Y L;  2BNS A;  4TQQ M;  4LWY L;  1YST L;  1RZH L;  1RY5 L;  1E14 M;  1MPS L;  2UWS L;  3DTA L;  1VRN L;  2HJ6 M;  3I4D M;  2JIY M;  1L9J M;  1QOV M;  2UX4 L;  3DU2 L;  2UXJ M;  4IN6 L;  3T6E L;  4N7L L;  1JGZ M;  1DV3 M;  4N7K M;  4CAS C;  4IN5 M;  1JGY M;  1K6N L;  2J8D M;  1AIJ M;  1RQK M;  1K6L M;  2GNU L;  2UXK M;  1JGW M;  4IN7 L;  3PRC M;  1RVJ M;  2JJ0 L;  4N7L M;  3D38 M;  2JBL M;  2UX3 L;  2UXM L;  2GMR L;  2UWU M;  3DSY M;  4HBJ L;  3WMM L;  2UWV M;  3DUQ L;  1PST M;  1RZZ M;  2WJN M;  1OGV L;  3T6D L;  1AIG M;  2UXL M;  2HG3 M;  1E6D M;  1M3X M;  5LRI M;  2HIT L;  3DTS M;  1F6N L;  3ZUM L;  1DXR L;  3G7F M;  2X5V M;  3DTR M;  1RG5 L;  1JH0 L;  1JGX L;  1S00 M;  3DU3 L;  1PRC L;  4H99 L;  4RCR M;  6PRC M;  3V3Y M;  4LWY M;  1KBY L;  1RZH M;  1YST M;  1RY5 M;  1MPS M;  7PRC L;  2UWS M;  1PCR L;  2RCR L;  1VRN M;  3DTA M;  5PRC L;  4H9L L;  1FNQ L;  2PRC L;  3ZUM M;  2J8C L;  2HG9 L;  1PSS L;  2UWT L;  2UX4 M;  1RGN L;  3DU2 M;  4H99 M;  4IN6 M;  1PRC M;  3T6E M;  1R2C L;  2HH1 L;  3V3Z L;  2BNP B;  5LSE L;  1UMX L;  1K6N M;  2HHK L;  2GNU M;  2X5U L;  4IN7 M;  2JJ0 M;  2UX3 M;  1DV6 L;  2WJM L;  2UXM M;  1FNP L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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